TCF7 (Bos taurus)
Sox

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00505 (HMG_box) IPR000910 ENSBTAG00000001002 T327614_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Tcf7
M00193_2.00 		Mus musculus
HNHNNNNNN
NNNNNNDND		 PBM
Badis et al.(2009)
Tcf7_0950 		0.741 1.000
Tcf7
M03532_2.00 		Mus musculus
AAASATCAAAGV
BCTTTGATSTTT		 SELEX
Jolma et al.(2013)
Tcf7_1 		0.741 1.000
TCF7
M05755_2.00 		Homo sapiens
DSATCAAWS
SWTTGATSH		 SELEX
Yin et al.(2017)
TCF7_eDBD_HT-SELEX_1 		0.741 1.000
TCF7
M05756_2.00 		Homo sapiens
WCWKCGYCYCGWTGW
WCAWCGRGRCGMWGW		 SELEX
Yin et al.(2017)
TCF7_eDBD_HT-SELEX_2 		0.741 1.000
TCF7
M05890_2.00 		Homo sapiens
NNASATCAAASNN
NNSTTTGATSTNN		 SMiLE-seq
Isakova et al.(2017)
TCF7 		0.741 1.000
TCF7
M09386_2.00 		Homo sapiens
NBBCTTTSAWSTBNBN
NVNVASWTSAAAGVVN		 Misc
Kulakovskiy et al.(2013)
TCF7_HUMAN.H11MO.0.A 		0.741 1.000
Tcf7
M09400_2.00 		Mus musculus
VVRVADSAAARVVVNV
BNBBBYTTTSHTBYBB		 Misc
Kulakovskiy et al.(2013)
TCF7_MOUSE.H11MO.0.A 		0.741 1.000
TCF7
M11294_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TCF1_Q5_01 		0.741 1.000
TCF7
M11295_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TCF1_Q5 		0.741 1.000
TCF7
M05757_2.00 		Homo sapiens
RSATCAAAS
STTTGATSY		 SELEX
Yin et al.(2017)
TCF7_eDBD_Methyl-HT-SELEX_1 		0.741 1.000
TCF7
M05758_2.00 		Homo sapiens
WCAWCGRGRCGMWGW
WCWKCGYCYCGWTGW		 SELEX
Yin et al.(2017)
TCF7_eDBD_Methyl-HT-SELEX_2 		0.741 1.000
Tcf7l2
M00198_2.00 		Mus musculus
NSWTCAAAVN
NBTTTGAWSN		 PBM
Badis et al.(2009)
Tcf7l2_3461 		0.716 0.986
Tcf7l2
M02646_2.00 		Mus musculus
SATCAAAGN
NCTTTGATS		 SELEX
Hallikas et al.(2006)
Tcf4 		0.716 0.986
TCF7L2
M08167_2.00 		Homo sapiens
NVASWTCAAAGVVN
NBBCTTTGAWSTBN		 ChIP-seq
Mathelier et al.(2014)
MA0523.1 		0.716 0.986
TCF7L2
M09393_2.00 		Homo sapiens
DGCAGSTGKS
SMCASCTGCH		 Misc
Kulakovskiy et al.(2013)
ITF2_HUMAN.H11MO.0.C 		0.716 0.986
TCF7L2
M09394_2.00 		Homo sapiens
VVASWTCAAAGVV
BBCTTTGAWSTBB		 Misc
Kulakovskiy et al.(2013)
TF7L2_HUMAN.H11MO.0.A 		0.716 0.986
Tcf7l2
M09401_2.00 		Mus musculus
VVASWTCAAAGVV
BBCTTTGAWSTBB		 Misc
Kulakovskiy et al.(2013)
TF7L2_MOUSE.H11MO.0.A 		0.716 0.986
TCF7L2
M09638_2.00 		Homo sapiens
CCTTTGAWST
ASWTCAAAGG		 Misc
Heinz et al.(2010)
K562-TCF7L2_GSE29196 		0.716 0.986
TCF7L2
M11316_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TCF4_Q5_01 		0.716 0.986
TCF7L2
M11317_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TCF4_Q5_02 		0.716 0.986
TCF7L2
M11318_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TCF4_Q5 		0.716 0.986
TCF7L2
M11319_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TCF7L2_06 		0.716 0.986
Lef1
M00200_2.00 		Mus musculus
NSWTCAAAVN
NBTTTGAWSN		 PBM
Badis et al.(2009)
Lef1_3504 		0.716 0.971
LEF1
M03511_2.00 		Homo sapiens
NRAGATCAAAGRVWW
WWBYCTTTGATCTYN		 SELEX
Jolma et al.(2013)
LEF1_1 		0.716 0.971
LEF1
M05771_2.00 		Homo sapiens
NSATCAAAS
STTTGATSN		 SELEX
Yin et al.(2017)
LEF1_eDBD_HT-SELEX_1 		0.716 0.971
LEF1
M05772_2.00 		Homo sapiens
WCATCGRGRCGCTGW
WCAGCGYCYCGATGW		 SELEX
Yin et al.(2017)
LEF1_eDBD_HT-SELEX_2 		0.716 0.971
LEF1
M05775_2.00 		Homo sapiens
ASATCAAAG
CTTTGATST		 SELEX
Yin et al.(2017)
LEF1_FL_HT-SELEX_1 		0.716 0.971
LEF1
M05776_2.00 		Homo sapiens
ACATCGRGRCGCTGW
WCAGCGYCYCGATGT		 SELEX
Yin et al.(2017)
LEF1_FL_HT-SELEX_2 		0.716 0.971
LEF1
M05895_2.00 		Homo sapiens
WTCAAAGNNN
NNNCTTTGAW		 SMiLE-seq
Isakova et al.(2017)
LEF1 		0.716 0.971
LEF1
M09392_2.00 		Homo sapiens
BSYTTTSWNNTBYH
DRVANNWSAAARSV		 Misc
Kulakovskiy et al.(2013)
LEF1_HUMAN.H11MO.0.A 		0.716 0.971
Lef1
M09402_2.00 		Mus musculus
BSYTTTSWNNTBYH
DRVANNWSAAARSV		 Misc
Kulakovskiy et al.(2013)
LEF1_MOUSE.H11MO.0.B 		0.716 0.971
LEF1
M11311_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$LEF1_Q2_01 		0.716 0.971
LEF1
M11312_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$LEF1_Q3 		0.716 0.971
LEF1
M11313_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$LEF1_Q4 		0.716 0.971
LEF1
M11314_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$LEF1_Q5_01 		0.716 0.971
LEF1
M11315_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$LEF1_Q5 		0.716 0.971
LEF1
M05773_2.00 		Homo sapiens
ASATCAAAG
CTTTGATST		 SELEX
Yin et al.(2017)
LEF1_eDBD_Methyl-HT-SELEX_1 		0.716 0.971
LEF1
M05774_2.00 		Homo sapiens
WCATCGRGGCGCTGW
WCAGCGCCYCGATGW		 SELEX
Yin et al.(2017)
LEF1_eDBD_Methyl-HT-SELEX_2 		0.716 0.971
LEF1
M05777_2.00 		Homo sapiens
ASATCAAAG
CTTTGATST		 SELEX
Yin et al.(2017)
LEF1_FL_Methyl-HT-SELEX_1 		0.716 0.971
LEF1
M05778_2.00 		Homo sapiens
ACATCGRGRCGCTGW
WCAGCGYCYCGATGT		 SELEX
Yin et al.(2017)
LEF1_FL_Methyl-HT-SELEX_2 		0.716 0.971
Tcf7l1
M00207_2.00 		Mus musculus
NNNNWWDN
NHWWNNNN		 PBM
Badis et al.(2009)
Tcf3_3787 		0.715 0.913
TCF7L1
M03512_2.00 		Homo sapiens
AAAGATCAAAGG
CCTTTGATCTTT		 SELEX
Jolma et al.(2013)
TCF7L1_1 		0.715 0.913
TCF7L1
M05779_2.00 		Homo sapiens
RSATCAAAG
CTTTGATSY		 SELEX
Yin et al.(2017)
TCF7L1_eDBD_HT-SELEX_1 		0.715 0.913
TCF7L1
M05780_2.00 		Homo sapiens
ACATCGRGRCGCTGW
WCAGCGYCYCGATGT		 SELEX
Yin et al.(2017)
TCF7L1_eDBD_HT-SELEX_2 		0.715 0.913
TCF7L1
M09395_2.00 		Homo sapiens
NBBCTTTGAWSTB
VASWTCAAAGVVN		 Misc
Kulakovskiy et al.(2013)
TF7L1_HUMAN.H11MO.0.B 		0.715 0.913
Tcf7l1
M09406_2.00 		Mus musculus
BBCTTTGAWST
ASWTCAAAGVV		 Misc
Kulakovskiy et al.(2013)
TF7L1_MOUSE.H11MO.0.A 		0.715 0.913
Tcf7l1
M09407_2.00 		Mus musculus
NDGCAGSTGBB
VVCASCTGCHN		 Misc
Kulakovskiy et al.(2013)
TFE2_MOUSE.H11MO.0.A 		0.715 0.913
TCF7L1
M11320_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TCF3_01 		0.715 0.913
TCF7L1
M11321_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TCF3_Q6_01 		0.715 0.913
TCF7L1
M11322_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TCF3_Q6 		0.715 0.913
TCF7L1
M05781_2.00 		Homo sapiens
CTTTGATSY
RSATCAAAG		 SELEX
Yin et al.(2017)
TCF7L1_eDBD_Methyl-HT-SELEX_1 		0.715 0.913
TCF7L1
M05782_2.00 		Homo sapiens
ACATCGRGRCGCTGW
WCAGCGYCYCGATGT		 SELEX
Yin et al.(2017)
TCF7L1_eDBD_Methyl-HT-SELEX_2 		0.715 0.913
pan
M06451_2.00 		Drosophila melanogaster
DWYCAAAD
HTTTGRWH		 B1H
Zhu et al.(2011)
pan_FlyReg_FBgn0085432 		0.695 0.913
pan
M08428_2.00 		Drosophila melanogaster
WHNAAAVRNRSCGM
KCGSYNYBTTTNDW		 ChIP-chip
Mathelier et al.(2014)
MA0237.2 		0.695 0.913
pan
M11337_2.00 		Drosophila melanogaster
AAGATCAAAGG
CCTTTGATCTT		 Transfac
Matys et al.(2006)
I$TCF_1 		0.695 0.913
pan
M11338_2.00 		Drosophila melanogaster Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
I$TCF_Q6 		0.695 0.913
pop-1
M00712_2.00 		Caenorhabditis elegans
NNHDWVNNNN
NNNNBWHDNN		 PBM
Narasimhan et al.(2015)
pTH9135 		0.515 0.551
For this family, TFs with SR scores > 0.415 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSBTAP00000001327 Sox 273 341
ENSBTAP00000001328 Sox 138 206
ENSBTAP00000001329 Sox 304 372

Links

Other Sox family TFs
Other Bos taurus TFs

512 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
FKH1 Saccharomyces cerevisiae YIL131C D
FKH2 Saccharomyces cerevisiae YNL068C D
CIMG_03727 Coccidioides immitis CIMG_03727 I
CLUG_01333 Candida lusitaniae CLUG_01333 I
CPAG_03572 Candida parapsilosis CPAG_03572 I
MCYG_01013 Microsporum canis MCYG_01013 I
PGUG_02044 Candida guilliermondii PGUG_02044 I
RO3G_14601 Rhizopus oryzae RO3G_14601 I
SNOG_11882 Stagonospora nodorum SNOG_11882 I
A1O1_05934 Capronia coronata A1O1_05934 I
A1O3_01051 Capronia epimyces A1O3_01051 I
A1O5_06245 Cladophialophora psammophila A1O5_06245 I
A1O9_06637 Exophiala aquamarina A1O9_06637 I
AGOS_AER369C Ashbya gossypii AGOS_AER369C I
ARB_07826 Arthroderma benhamiae ARB_07826 I
BDDG_09123 Blastomyces dermatitidis BDDG_09123 I
BN7_2053 Wickerhamomyces ciferrii BN7_2053 I
ACLA_039840 Aspergillus clavatus CADACLAG00004044 I
CADAFLAG00002435 Aspergillus flavus CADAFLAG00002435 I
AFUA_3G11960 Aspergillus fumigatus CADAFUAG00005312 I
CADANGAG00002306 Aspergillus niger CADANGAG00002306 I
ANIA_02854 Aspergillus nidulans CADANIAG00010236 I
CADAORAG00001350 Aspergillus oryzae CADAORAG00001350 I
ATEG_04739 Aspergillus terreus CADATEAG00006672 I
NFIA_065340 Neosartorya fischeri CADNFIAG00005675 I
CAGL0J10120g Candida glabrata CAGL0J10120g I
CANTEDRAFT_130674 Candida tenuis CANTEDRAFT_130674 I
CaO19.12844 Candida albicans CaO19.12844 I
CaO19.5389 Candida albicans CaO19.5389 I
CD36_80620 Candida dubliniensis CD36_80620 I
CLUG_01333 Clavispora lusitaniae CLUG_01333 I
CORT_0D07370 Candida orthopsilosis CORT_0D07370 I
CPC735_005630 Coccidioides posadasii CPC735_005630 I
CTRG_05718 Candida tropicalis CTRG_05718 I
DEHA2A08910g Debaryomyces hansenii DEHA2A08910g I
Ecym_5396 Eremothecium cymbalariae Ecym_5396 I
ENSAMXG00000015869 Astyanax mexicanus ENSAMXG00000015869 I
foxj2 Danio rerio ENSDARG00000057680 I
foxj2 Gasterosteus aculeatus ENSGACG00000010572 I
ENSGMOG00000004406 Gadus morhua ENSGMOG00000004406 I
ENSONIG00000012813 Oreochromis niloticus ENSONIG00000012813 I
ENSORLG00000011631 Oryzias latipes ENSORLG00000011631 I
ENSPFOG00000011037 Poecilia formosa ENSPFOG00000011037 I
foxj2 Tetraodon nigroviridis ENSTNIG00000008113 I
foxj2 Takifugu rubripes ENSTRUG00000006168 I
EPUS_04989 Endocarpon pusillum EPUS_04989 I
EURHEDRAFT_84089 Aspergillus ruber EURHEDRAFT_84089 I
G210_3526 Candida maltosa G210_3526 I
GNLVRS01_PISO0E05328g Millerozyma farinosa GNLVRS01_PISO0E05328g I
GNLVRS01_PISO0F06649g Millerozyma farinosa GNLVRS01_PISO0F06649g I
H101_06966 Trichophyton interdigitale H101_06966 I
H102_08252 Trichophyton rubrum H102_08252 I
H105_08280 Trichophyton soudanense H105_08280 I
HCBG_07375 Histoplasma capsulatum HCBG_07375 I
HMPREF1120_02814 Exophiala dermatitidis HMPREF1120_02814 I
HMPREF1541_00364 Cyphellophora europaea HMPREF1541_00364 I
HPODL_02534 Ogataea parapolymorpha HPODL_02534 I
JL09_g1492 Pichia kudriavzevii JL09_g1492 I
KAFR_0J00890 Kazachstania africana KAFR_0J00890 I
KAFR_0J01720 Kazachstania africana KAFR_0J01720 I
KLLA0_F04631g Kluyveromyces lactis KLLA0_F04631g I
KLTH0G09086g Lachancea thermotolerans KLTH0G09086g I
KNAG_0M01920 Kazachstania naganishii KNAG_0M01920 I
Kpol_1003p6 Vanderwaltozyma polyspora Kpol_1003p6 I
Kpol_1039p10 Vanderwaltozyma polyspora Kpol_1039p10 I
KUCA_T00002120001 Kuraishia capsulata KUCA_T00002120001 I
LALA0_S04e08592g Lachancea lanzarotensis LALA0_S04e08592g I
LELG_02201 Lodderomyces elongisporus LELG_02201 I
MCYG_01013 Arthroderma otae MCYG_01013 I
MGYG_00973 Microsporum gypseum MGYG_00973 I
NCAS_0B06560 Naumovozyma castellii NCAS_0B06560 I
NCAS_0G02930 Naumovozyma castellii NCAS_0G02930 I
NDAI_0F02370 Naumovozyma dairenensis NDAI_0F02370 I
NEPG_01226 Nematocida parisii ertm1 NEPG_01226 I
NERG_01460 Nematocida sp NERG_01460 I
PCH_Pc18g00430 Penicillium rubens PCH_Pc18g00430 I
PDE_05162 Penicillium oxalicum PDE_05162 I
PDIP_75040 Penicillium digitatum PDIP_75040 I
PEX1_059580 Penicillium expansum PEX1_059580 I
PGUG_02044 Meyerozyma guilliermondii PGUG_02044 I
PICST_82259 Scheffersomyces stipitis PICST_82259 I
PITC_013300 Penicillium italicum PITC_013300 I
PMAA_023910 Talaromyces marneffei PMAA_023910 I
PNEG_01242 Pneumocystis murina PNEG_01242 I
PV05_11650 Exophiala xenobiotica PV05_11650 I
PV06_03424 Exophiala oligosperma PV06_03424 I
PV07_01813 Cladophialophora immunda PV07_01813 I
PV08_05339 Exophiala spinifera PV08_05339 I
PV10_08910 Exophiala mesophila PV10_08910 I
PV11_07398 Exophiala sideris PV11_07398 I
PVAR5_5344 Byssochlamys spectabilis PVAR5_5344 I
SNOG_11882 Phaeosphaeria nodorum SNOG_11882 I
SPAPADRAFT_141274 Spathaspora passalidarum SPAPADRAFT_141274 I
SU7_2990 Saccharomyces arboricola SU7_2990 I
TBLA_0E03730 Tetrapisispora blattae TBLA_0E03730 I
TBLA_0G02620 Tetrapisispora blattae TBLA_0G02620 I
TDEL_0C04470 Torulaspora delbrueckii TDEL_0C04470 I
TEQG_01043 Trichophyton equinum TEQG_01043 I
TESG_04573 Trichophyton tonsurans TESG_04573 I
TPHA_0F01390 Tetrapisispora phaffii TPHA_0F01390 I
TRV_05777 Trichophyton verrucosum TRV_05777 I
TSTA_032340 Talaromyces stipitatus TSTA_032340 I
U727_00433931341 Penicillium solitum U727_00433931341 I
UREG_07540 Uncinocarpus reesii UREG_07540 I
YALI0_C09185g Yarrowia lipolytica YALI0_C09185g I
Z517_08036 Fonsecaea pedrosoi Z517_08036 I
Z518_04151 Rhinocladiella mackenziei Z518_04151 I
Z519_10766 Cladophialophora bantiana Z519_10766 I
ZYRO0A01254g Zygosaccharomyces rouxii ZYRO0A01254g I
e_gw1.4.1134.1 Mucor circinelloides e_gw1.4.1134.1 I
estExt_fgeneshPB_pg.C_490005 Phycomyces blakesleeanus estExt_fgeneshPB_pg.C_490005 I
estExt_gwp_genewisePlus_worm.C_chr_2.12159 Pichia stipitis estExt_gwp_genewisePlus_worm.C_chr_2.12159 I
gw1.4.1133.1 Mucor circinelloides gw1.4.1133.1 I
PredSwiss_CON2884.2 Pneumocystis carinii PredSwiss_CON2884.2 I
Scas_Contig662.9 Saccharomyces castellii Scas_Contig662.9 I
Scas_Contig694.13 Saccharomyces castellii Scas_Contig694.13 I
10722_YIL131C Saccharomyces paradoxus 10722_YIL131C I
18607_YNL068C Saccharomyces mikatae 18607_YNL068C I
19078_YNL068C Saccharomyces paradoxus 19078_YNL068C I
fgenesh1_pm.00866_#_484 Aspergillus carbonarius fgenesh1_pm.00866_#_484 I
KLTH0G09086g Kluyveromyces thermotolerans KLTH0G09086g I
Kwal_4740 Kluyveromyces waltii Kwal_4740 I
Pc18g00430 Penicillium chrysogenum Pc18g00430 I
PMAA_023910 Penicillium marneffei PMAA_023910 I
SAKL0E09020g Lachancea kluyveri SAKL0E09020g I
XP_002493610.1 Pichia pastoris XP_002493610.1 I