tbx-8 (Caenorhabditis elegans)
T-box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00907 (T-box) IPR001699 WBGene00006545 T340935_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in embryonic body morphogenesis. Located in nucleus. Is expressed in several structures, including Ea; Eal; Ear; Ep; and Epl. Human ortholog(s) of this gene implicated in asthma, nasal polyps, and aspirin intolerance and autistic disorder. Orthologous to several human genes including TBR1 (T-box brain transcription factor 1) and EOMES (eomesodermin). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
T07C4.2 T-box 7 195

Links

Other T-box family TFs
Other Caenorhabditis elegans TFs

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5 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action