NCBI Gene Info:Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in embryonic body morphogenesis. Located in nucleus. Is expressed in several structures, including Ea; Eal; Ear; Ep; and Epl. Human ortholog(s) of this gene implicated in asthma, nasal polyps, and aspirin intolerance and autistic disorder. Orthologous to several human genes including TBR1 (T-box brain transcription factor 1) and EOMES (eomesodermin). [provided by Alliance of Genome Resources, Apr 2022] |