| NCBI Gene Info:Predicted to enable DNA binding activity. Predicted to contribute to nucleosome binding activity. Involved in gonad development; nematode larval development; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including excretory cell; gonad; intestine; tail precursor cell; and vulva. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in several diseases, including Coffin-Siris syndrome (multiple); breast cancer; carcinoma (multiple); gastrointestinal system cancer (multiple); and neuroblastoma. Orthologous to human ARID1A (AT-rich interaction domain 1A) and ARID1B (AT-rich interaction domain 1B). [provided by Alliance of Genome Resources, Apr 2022] |