CIS-BP Database: Catalog of Inferred Sequence Binding Preferences

TF Information

KLF3 *(Canis familiaris)* C2H2 ZF
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF00096 (zf-C2H2)	IPR007087	ENSCAFG00000016180	T088403_2.00	Ensembl (2018-Dec-8)	Link out
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
KLF3 M04418_2.00	Homo sapiens	RRCCRCGCCCH	DGGGCGYGGYY	SELEX Yin et al.(2017) KLF3_FL_HT-SELEX	0.827	1.000
KLF3 M08876_2.00	Homo sapiens	NSNNVCCMCRCCCHBBBBN	NVVVVDGGGYGKGGBNNSN	Misc Kulakovskiy et al.(2013) KLF3_HUMAN.H11MO.0.B	0.827	1.000
Klf3 M08982_2.00	Mus musculus	NSNNVCCMCRCCCHBBBBN	NVVVVDGGGYGKGGBNNSN	Misc Kulakovskiy et al.(2013) KLF3_MOUSE.H11MO.0.A	0.827	1.000
KLF3 M10172_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$KLF3_Q3_01	0.827	1.000
KLF3 M10173_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$KLF3_Q3	0.827	1.000
KLF3 M04419_2.00	Homo sapiens	DRCCACGCCCH	DGGGCGTGGYH	SELEX Yin et al.(2017) KLF3_FL_Methyl-HT-SELEX_1	0.827	1.000
KLF3 M04420_2.00	Homo sapiens	RRSCGCARCCCN	NGGGYTGCGSYY	SELEX Yin et al.(2017) KLF3_FL_Methyl-HT-SELEX_2	0.827	1.000
KLF5 M04410_2.00	Homo sapiens	NMCACRCCCH	DGGGYGTGKN	SELEX Yin et al.(2017) KLF5_eDBD_HT-SELEX	0.804	0.855
KLF5 M08086_2.00	Homo sapiens	BCCMCDCCCH	DGGGHGKGGV	ChIP-seq Mathelier et al.(2014) MA0599.1	0.804	0.855
KLF5 M08868_2.00	Homo sapiens	NHVNRCCMCDCCCH	DGGGHGKGGYNBDN	Misc Kulakovskiy et al.(2013) KLF5_HUMAN.H11MO.0.A	0.804	0.855
Klf5 M08965_2.00	Mus musculus	KCCMCDCCCHBBBCH	DGVVVDGGGHGKGGM	Misc Kulakovskiy et al.(2013) KLF5_MOUSE.H11MO.0.A	0.804	0.855
KLF5 M09502_2.00	Homo sapiens	GCCMCRCCCH	DGGGYGKGGC	Misc Heinz et al.(2010) LoVo-KLF5_GSE49402	0.804	0.855
KLF5 M10149_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$BTEB2_Q3_01	0.804	0.855
KLF5 M10150_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$BTEB2_Q3	0.804	0.855
KLF5 M04411_2.00	Homo sapiens	NMCACRCCYH	DRGGYGTGKN	SELEX Yin et al.(2017) KLF5_eDBD_Methyl-HT-SELEX	0.804	0.855
Klf12 M00787_2.00	Mus musculus	NNHMCRCCCH	DGGGYGKDNN	PBM Weirauch et al.(2013) pTH0977	0.801	0.942
Klf12 M02937_2.00	Mus musculus	GRCCACGCCCWHHHN	NDDDWGGGCGTGGYC	SELEX Jolma et al.(2013) Klf12_1	0.801	0.942
KLF12 M04430_2.00	Homo sapiens	DRCCACGCCCH	DGGGCGTGGYH	SELEX Yin et al.(2017) KLF12_FL_HT-SELEX	0.801	0.942
KLF12 M08299_2.00	Homo sapiens	SBNVGCCMCGCCCHB	VDGGGCGKGGCBNVS	ChIP-seq Schmitges et al.(2016) Q9Y4X4.MEME	0.801	0.942
KLF12 M08879_2.00	Homo sapiens	GCCCCGCCCYB	VRGGGCGGGGC	Misc Kulakovskiy et al.(2013) KLF12_HUMAN.H11MO.0.C	0.801	0.942
KLF12 M10186_2.00	Homo sapiens	HMYACDG	CHGTRKD	Transfac Matys et al.(2006) V$AP2REP_01	0.801	0.942
KLF12 M04431_2.00	Homo sapiens	RGSCGACGCCCN	NGGGCGTCGSCY	SELEX Yin et al.(2017) KLF12_FL_Methyl-HT-SELEX_1	0.801	0.942
KLF12 M04432_2.00	Homo sapiens	NRCCACGCCCH	DGGGCGTGGYN	SELEX Yin et al.(2017) KLF12_FL_Methyl-HT-SELEX_2	0.801	0.942
Klf7 M00134_2.00	Mus musculus	NHHMCRCCCH	DGGGYGKDDN	PBM Badis et al.(2009) Klf7_0974	0.797	0.826
KLF7 M08298_2.00	Homo sapiens	VVCHMCGCCCH	DGGGCGKDGBB	ChIP-seq Schmitges et al.(2016) O75840.MEME	0.797	0.826
KLF4 M04463_2.00	Homo sapiens	NVCCACRCCCH	DGGGYGTGGBN	SELEX Yin et al.(2017) KLF4_eDBD_HT-SELEX	0.784	0.826
KLF4 M08091_2.00	Homo sapiens	MCACACCCWNN	NNWGGGTGTGK	ChIP-seq Mathelier et al.(2014) MA0039.3	0.784	0.826
Klf4 M08021_2.00	Mus musculus	VRCCMCRCCCH	DGGGYGKGGYB	ChIP-seq Chen et al.(2011) SRP000217_Klf4	0.784	0.826
KLF4 M08243_2.00	Homo sapiens	RCCMCRCCCH	DGGGYGKGGY	ChIP-seq Najafabadi et al.(2015b) KLF14	0.784	0.826
KLF4 M08894_2.00	Homo sapiens	RCCMCRCCCH	DGGGYGKGGY	Misc Kulakovskiy et al.(2013) KLF4_HUMAN.H11MO.0.A	0.784	0.826
Klf4 M08964_2.00	Mus musculus	GCCMCRCCCWBYBBN	NVVRVWGGGYGKGGC	Misc Kulakovskiy et al.(2013) KLF4_MOUSE.H11MO.0.A	0.784	0.826
KLF4 M10217_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$GKLF_02	0.784	0.826
KLF4 M10218_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$GKLF_Q3_01	0.784	0.826
KLF4 M10219_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$GKLF_Q3	0.784	0.826
KLF4 M10220_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$GKLF_Q4	0.784	0.826
KLF4 M04464_2.00	Homo sapiens	NVCCMCRCCCN	NGGGYGKGGBN	SELEX Yin et al.(2017) KLF4_eDBD_Methyl-HT-SELEX	0.784	0.826
KLF6 M04400_2.00	Homo sapiens	NVMCACRCCCH	DGGGYGTGKBN	SELEX Yin et al.(2017) KLF6_eDBD_HT-SELEX	0.781	0.826
KLF6 M08857_2.00	Homo sapiens	BYBYVNBCYMCDCCCYBBN	NVVRGGGHGKRGVNBRVRV	Misc Kulakovskiy et al.(2013) KLF6_HUMAN.H11MO.0.A	0.781	0.826
Klf6 M08962_2.00	Mus musculus	BYBYVNBCYMCDCCCYBBN	NVVRGGGHGKRGVNBRVRV	Misc Kulakovskiy et al.(2013) KLF6_MOUSE.H11MO.0.B	0.781	0.826
KLF6 M10113_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$CPBP_Q6	0.781	0.826
KLF6 M04401_2.00	Homo sapiens	NRCCACGCCCH	DGGGCGTGGYN	SELEX Yin et al.(2017) KLF6_eDBD_Methyl-HT-SELEX	0.781	0.826
luna M03704_2.00	Drosophila melanogaster	RCCACRCCCH	DGGGYGTGGY	SELEX Nitta et al.(2015) luna_1	0.781	0.812
KLF2 M04455_2.00	Homo sapiens	NVCCMCRCCCH	DGGGYGKGGBN	SELEX Yin et al.(2017) KLF2_eDBD_HT-SELEX	0.781	0.812
luna M06163_2.00	Drosophila melanogaster	RRMHMCRCCC	GGGYGKDKYY	B1H Zhu et al.(2011) luna_SANGER_5_FBgn0040765	0.781	0.812
luna M06164_2.00	Drosophila melanogaster	DRCCMCGCCCHNNN	NNNDGGGCGKGGYH	B1H Zhu et al.(2011) luna_SOLEXA_5_FBgn0040765	0.781	0.812
KLF2 M10210_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$LKLF_Q3	0.781	0.812
KLF2 M10211_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$LKLF_Q6	0.781	0.812
KLF2 M04456_2.00	Homo sapiens	NVCCMCRCCCN	NGGGYGKGGBN	SELEX Yin et al.(2017) KLF2_eDBD_Methyl-HT-SELEX	0.781	0.812
KLF1 M00226_2.00	Homo sapiens	CMCGCCCM	KGGGCGKG	PBM Barrera et al.(2016) KLF1_REF	0.768	0.783
KLF1 M08293_2.00	Homo sapiens	NVNNNRCCMCRCCCH	DGGGYGKGGYNNNBN	ChIP-seq Schmitges et al.(2016) Q13351.MEME	0.768	0.783
KLF1 M08871_2.00	Homo sapiens	SVNDGCCMCRCCCH	DGGGYGKGGCHNBS	Misc Kulakovskiy et al.(2013) KLF1_HUMAN.H11MO.0.A	0.768	0.783
KLF1 M10163_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$EKLF_Q5_01	0.768	0.783
KLF1 M10164_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$EKLF_Q5	0.768	0.783
KLF1 M00224_2.00	Homo sapiens	YMCGCCCH	DGGGCGKR	PBM Barrera et al.(2016) KLF1_H299Y	0.768	0.768
Klf8 M00779_2.00	Mus musculus	NNNMCRCCYN	NRGGYGKNNN	PBM Weirauch et al.(2013) pTH3086	0.766	0.870
KLF8 M08867_2.00	Homo sapiens	CACMCMCKG	CMGKGKGTG	Misc Kulakovskiy et al.(2013) KLF8_HUMAN.H11MO.0.C	0.766	0.870
Klf8 M09000_2.00	Mus musculus	CACMCMCKG	CMGKGKGTG	Misc Kulakovskiy et al.(2013) KLF8_MOUSE.H11MO.0.C	0.766	0.870
KLF8 M10147_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$KLF8_Q5_01	0.766	0.870
KLF8 M10148_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$KLF8_Q5	0.766	0.870
Klf1 M08099_2.00	Mus musculus	NRCCACACCCW	WGGGTGTGGYN	ChIP-seq Mathelier et al.(2014) MA0493.1	0.765	0.768
Klf1 M09008_2.00	Mus musculus	MVMNSCCMCRCCCH	DGGGYGKGGSNKBK	Misc Kulakovskiy et al.(2013) KLF1_MOUSE.H11MO.0.A	0.765	0.768
Klf1 M09516_2.00	Mus musculus	DRCCACACCCWN	NWGGGTGTGGYH	Misc Heinz et al.(2010) Erythrocyte-Klf1_GSE20478	0.765	0.768
dar1 M06171_2.00	Drosophila melanogaster	RMCACACCCWH	DWGGGTGTGKY	B1H Zhu et al.(2011) CG12029_SANGER_10_FBgn0035454	0.758	0.768
dar1 M06172_2.00	Drosophila melanogaster	NNNRCCACRCCCHNN	NNDGGGYGTGGYNNN	B1H Zhu et al.(2011) CG12029_SOLEXA_5_FBgn0035454	0.758	0.768
For this family, TFs with SR scores > 0.755* will likely have a similar motif*

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
ENSCAFP00000023845	C2H2 ZF	260	284	HRCDYDGCNKVYTKSSHLKAHRRTH
ENSCAFP00000023845	C2H2 ZF	290	314	YKCTWEGCTWKFARSDELTRHFRKH
ENSCAFP00000023845	C2H2 ZF	320	342	FQCPDCDRSFSRSDHLALHRKRH

Links
Other C2H2 ZF family TFs
Other *Canis familiaris* TFs

736 Related TFs

Name	Species	Gene ID	Motif Evidence	SR Score	Action
ACEP14716	Atta cephalotes	ACEP14716	I
ACEP26693	Atta cephalotes	ACEP26693	N
AFAF002703	Anopheles farauti	AFAF002703	N
AFUN015812	Anopheles funestus	AFUN015812	N
AFUN015813	Anopheles funestus	AFUN015813	N
Cflo_01074--XP_394229.2_APIME	Camponotus floridanus	Cflo_01074--XP_394229.2_APIME	N
Cflo_04179--XP_623088.1_APIME	Camponotus floridanus	Cflo_04179--XP_623088.1_APIME	I
DAPPUDRAFT_194512	Daphnia pulex	DAPPUDRAFT_194512	I
ENSOANG00000022637	Ornithorhynchus anatinus	ENSOANG00000022637	I
GB47180	Apis mellifera	GB47180	I
GB54865	Apis mellifera	GB54865	N
HMEL016424	Heliconius melpomene	HMEL016424	I
Hsal_00608--XP_394229.2_APIME	Harpegnathos saltator	Hsal_00608--XP_394229.2_APIME	N
KGM_04261	Danaus plexippus	KGM_04261	I
LDEC000156	Leptinotarsa decemlineata	LDEC000156	N
LLOJ006615	Lutzomyia longipalpis	LLOJ006615	I
MCINX007129	Melitaea cinxia	MCINX007129	I
NV15957	Nasonia vitripennis	NV15957	N
PHUM533080	Pediculus humanus	PHUM533080	I
PPAI004956	Phlebotomus papatasi	PPAI004956	I
SINV24483	Solenopsis invicta	SINV24483	I

KLF3 (Canis familiaris) C2H2 ZF

TF Information

Directly determined binding motifs

Motifs from related TFs

DNA Binding Domains

Links

736 Related TFs

KLF3 **(Canis familiaris)
C2H2 ZF**