ZNF408 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000175213 T095139_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
The protein encoded by this gene contains ten tandem zinc fingers and an N-terminal SET domain, so it is likely a DNA binding protein that interacts with other proteins. In adults, the encoded protein is expressed most highly in retina. Consequently, defects in this gene have been associated with familial exudative vitreoretinopathy (FEVR) and retinitis pigmentosa (RP). [provided by RefSeq, Dec 2016]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000309606 C2H2 ZF 353 375
ENSP00000309606 C2H2 ZF 381 403
ENSP00000309606 C2H2 ZF 409 431
ENSP00000309606 C2H2 ZF 437 459
ENSP00000309606 C2H2 ZF 468 490
ENSP00000309606 C2H2 ZF 496 518
ENSP00000309606 C2H2 ZF 524 546
ENSP00000309606 C2H2 ZF 551 573
ENSP00000309606 C2H2 ZF 579 601
ENSP00000309606 C2H2 ZF 607 629

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

Invalid Input OrderBy

29 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action