Klf12 (Mus musculus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSMUSG00000072294 T101456_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Klf12
M00787_2.00		 Mus musculus
NNHMCRCCCH
DGGGYGKDNN		 PBM
Weirauch et al.(2013)
pTH0977		 (Direct) (Direct)
Klf12
M02937_2.00		 Mus musculus
GRCCACGCCCWHHHN
NDDDWGGGCGTGGYC		 SELEX
Jolma et al.(2013)
Klf12_1		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
KLF12
M04430_2.00 		Homo sapiens
DRCCACGCCCH
DGGGCGTGGYH		 SELEX
Yin et al.(2017)
KLF12_FL_HT-SELEX 		0.827 1.000
KLF12
M08299_2.00 		Homo sapiens
SBNVGCCMCGCCCHB
VDGGGCGKGGCBNVS		 ChIP-seq
Schmitges et al.(2016)
Q9Y4X4.MEME 		0.827 1.000
KLF12
M08879_2.00 		Homo sapiens
GCCCCGCCCYB
VRGGGCGGGGC		 Misc
Kulakovskiy et al.(2013)
KLF12_HUMAN.H11MO.0.C 		0.827 1.000
KLF12
M10186_2.00 		Homo sapiens
HMYACDG
CHGTRKD		 Transfac
Matys et al.(2006)
V$AP2REP_01 		0.827 1.000
KLF12
M04431_2.00 		Homo sapiens
RGSCGACGCCCN
NGGGCGTCGSCY		 SELEX
Yin et al.(2017)
KLF12_FL_Methyl-HT-SELEX_1 		0.827 1.000
KLF12
M04432_2.00 		Homo sapiens
NRCCACGCCCH
DGGGCGTGGYN		 SELEX
Yin et al.(2017)
KLF12_FL_Methyl-HT-SELEX_2 		0.827 1.000
Klf7
M00134_2.00 		Mus musculus
NHHMCRCCCH
DGGGYGKDDN		 PBM
Badis et al.(2009)
Klf7_0974 		0.806 0.841
KLF7
M08298_2.00 		Homo sapiens
VVCHMCGCCCH
DGGGCGKDGBB		 ChIP-seq
Schmitges et al.(2016)
O75840.MEME 		0.806 0.841
KLF3
M04418_2.00 		Homo sapiens
RRCCRCGCCCH
DGGGCGYGGYY		 SELEX
Yin et al.(2017)
KLF3_FL_HT-SELEX 		0.801 0.942
KLF3
M08876_2.00 		Homo sapiens
NSNNVCCMCRCCCHBBBBN
NVVVVDGGGYGKGGBNNSN		 Misc
Kulakovskiy et al.(2013)
KLF3_HUMAN.H11MO.0.B 		0.801 0.942
Klf3
M08982_2.00 		Mus musculus
NSNNVCCMCRCCCHBBBBN
NVVVVDGGGYGKGGBNNSN		 Misc
Kulakovskiy et al.(2013)
KLF3_MOUSE.H11MO.0.A 		0.801 0.942
KLF3
M10172_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$KLF3_Q3_01 		0.801 0.942
KLF3
M10173_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$KLF3_Q3 		0.801 0.942
KLF3
M04419_2.00 		Homo sapiens
DRCCACGCCCH
DGGGCGTGGYH		 SELEX
Yin et al.(2017)
KLF3_FL_Methyl-HT-SELEX_1 		0.801 0.942
KLF3
M04420_2.00 		Homo sapiens
RRSCGCARCCCN
NGGGYTGCGSYY		 SELEX
Yin et al.(2017)
KLF3_FL_Methyl-HT-SELEX_2 		0.801 0.942
luna
M03704_2.00 		Drosophila melanogaster
RCCACRCCCH
DGGGYGTGGY		 SELEX
Nitta et al.(2015)
luna_1 		0.790 0.826
luna
M06163_2.00 		Drosophila melanogaster
RRMHMCRCCC
GGGYGKDKYY		 B1H
Zhu et al.(2011)
luna_SANGER_5_FBgn0040765 		0.790 0.826
luna
M06164_2.00 		Drosophila melanogaster
DRCCMCGCCCHNNN
NNNDGGGCGKGGYH		 B1H
Zhu et al.(2011)
luna_SOLEXA_5_FBgn0040765 		0.790 0.826
KLF6
M04400_2.00 		Homo sapiens
NVMCACRCCCH
DGGGYGTGKBN		 SELEX
Yin et al.(2017)
KLF6_eDBD_HT-SELEX 		0.790 0.812
KLF6
M08857_2.00 		Homo sapiens
BYBYVNBCYMCDCCCYBBN
NVVRGGGHGKRGVNBRVRV		 Misc
Kulakovskiy et al.(2013)
KLF6_HUMAN.H11MO.0.A 		0.790 0.812
Klf6
M08962_2.00 		Mus musculus
BYBYVNBCYMCDCCCYBBN
NVVRGGGHGKRGVNBRVRV		 Misc
Kulakovskiy et al.(2013)
KLF6_MOUSE.H11MO.0.B 		0.790 0.812
KLF6
M10113_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CPBP_Q6 		0.790 0.812
KLF6
M04401_2.00 		Homo sapiens
NRCCACGCCCH
DGGGCGTGGYN		 SELEX
Yin et al.(2017)
KLF6_eDBD_Methyl-HT-SELEX 		0.790 0.812
KLF5
M04410_2.00 		Homo sapiens
NMCACRCCCH
DGGGYGTGKN		 SELEX
Yin et al.(2017)
KLF5_eDBD_HT-SELEX 		0.781 0.841
KLF5
M08086_2.00 		Homo sapiens
BCCMCDCCCH
DGGGHGKGGV		 ChIP-seq
Mathelier et al.(2014)
MA0599.1 		0.781 0.841
KLF5
M08868_2.00 		Homo sapiens
NHVNRCCMCDCCCH
DGGGHGKGGYNBDN		 Misc
Kulakovskiy et al.(2013)
KLF5_HUMAN.H11MO.0.A 		0.781 0.841
Klf5
M08965_2.00 		Mus musculus
KCCMCDCCCHBBBCH
DGVVVDGGGHGKGGM		 Misc
Kulakovskiy et al.(2013)
KLF5_MOUSE.H11MO.0.A 		0.781 0.841
KLF5
M09502_2.00 		Homo sapiens
GCCMCRCCCH
DGGGYGKGGC		 Misc
Heinz et al.(2010)
LoVo-KLF5_GSE49402 		0.781 0.841
KLF5
M10149_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$BTEB2_Q3_01 		0.781 0.841
KLF5
M10150_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$BTEB2_Q3 		0.781 0.841
KLF5
M04411_2.00 		Homo sapiens
NMCACRCCYH
DRGGYGTGKN		 SELEX
Yin et al.(2017)
KLF5_eDBD_Methyl-HT-SELEX 		0.781 0.841
Klf8
M00779_2.00 		Mus musculus
NNNMCRCCYN
NRGGYGKNNN		 PBM
Weirauch et al.(2013)
pTH3086 		0.772 0.870
KLF8
M08867_2.00 		Homo sapiens
CACMCMCKG
CMGKGKGTG		 Misc
Kulakovskiy et al.(2013)
KLF8_HUMAN.H11MO.0.C 		0.772 0.870
Klf8
M09000_2.00 		Mus musculus
CACMCMCKG
CMGKGKGTG		 Misc
Kulakovskiy et al.(2013)
KLF8_MOUSE.H11MO.0.C 		0.772 0.870
KLF8
M10147_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$KLF8_Q5_01 		0.772 0.870
KLF8
M10148_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$KLF8_Q5 		0.772 0.870
dar1
M06171_2.00 		Drosophila melanogaster
RMCACACCCWH
DWGGGTGTGKY		 B1H
Zhu et al.(2011)
CG12029_SANGER_10_FBgn0035454 		0.767 0.783
dar1
M06172_2.00 		Drosophila melanogaster
NNNRCCACRCCCHNN
NNDGGGYGTGGYNNN		 B1H
Zhu et al.(2011)
CG12029_SOLEXA_5_FBgn0035454 		0.767 0.783
KLF4
M04463_2.00 		Homo sapiens
NVCCACRCCCH
DGGGYGTGGBN		 SELEX
Yin et al.(2017)
KLF4_eDBD_HT-SELEX 		0.762 0.812
KLF4
M08091_2.00 		Homo sapiens
MCACACCCWNN
NNWGGGTGTGK		 ChIP-seq
Mathelier et al.(2014)
MA0039.3 		0.762 0.812
Klf4
M08021_2.00 		Mus musculus
VRCCMCRCCCH
DGGGYGKGGYB		 ChIP-seq
Chen et al.(2011)
SRP000217_Klf4 		0.762 0.812
KLF4
M08243_2.00 		Homo sapiens
RCCMCRCCCH
DGGGYGKGGY		 ChIP-seq
Najafabadi et al.(2015b)
KLF14 		0.762 0.812
KLF4
M08894_2.00 		Homo sapiens
RCCMCRCCCH
DGGGYGKGGY		 Misc
Kulakovskiy et al.(2013)
KLF4_HUMAN.H11MO.0.A 		0.762 0.812
Klf4
M08964_2.00 		Mus musculus
GCCMCRCCCWBYBBN
NVVRVWGGGYGKGGC		 Misc
Kulakovskiy et al.(2013)
KLF4_MOUSE.H11MO.0.A 		0.762 0.812
KLF4
M10217_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GKLF_02 		0.762 0.812
KLF4
M10218_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GKLF_Q3_01 		0.762 0.812
KLF4
M10219_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GKLF_Q3 		0.762 0.812
KLF4
M10220_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GKLF_Q4 		0.762 0.812
KLF4
M04464_2.00 		Homo sapiens
NVCCMCRCCCN
NGGGYGKGGBN		 SELEX
Yin et al.(2017)
KLF4_eDBD_Methyl-HT-SELEX 		0.762 0.812
KLF1
M00226_2.00 		Homo sapiens
CMCGCCCM
KGGGCGKG		 PBM
Barrera et al.(2016)
KLF1_REF 		0.762 0.783
KLF1
M08293_2.00 		Homo sapiens
NVNNNRCCMCRCCCH
DGGGYGKGGYNNNBN		 ChIP-seq
Schmitges et al.(2016)
Q13351.MEME 		0.762 0.783
KLF1
M08871_2.00 		Homo sapiens
SVNDGCCMCRCCCH
DGGGYGKGGCHNBS		 Misc
Kulakovskiy et al.(2013)
KLF1_HUMAN.H11MO.0.A 		0.762 0.783
KLF1
M10163_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$EKLF_Q5_01 		0.762 0.783
KLF1
M10164_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$EKLF_Q5 		0.762 0.783
KLF1
M00224_2.00 		Homo sapiens
YMCGCCCH
DGGGCGKR		 PBM
Barrera et al.(2016)
KLF1_H299Y 		0.762 0.768
CG42741
M06169_2.00 		Drosophila melanogaster
RCCACRCCCWHY
RDWGGGYGTGGY		 B1H
Zhu et al.(2011)
CG9895_SANGER_10_FBgn0034810 		0.759 0.826
CG42741
M06170_2.00 		Drosophila melanogaster
VRCCACRCCCH
DGGGYGTGGYB		 B1H
Zhu et al.(2011)
CG9895_SOLEXA_5_FBgn0034810 		0.759 0.826
KLF2
M04455_2.00 		Homo sapiens
NVCCMCRCCCH
DGGGYGKGGBN		 SELEX
Yin et al.(2017)
KLF2_eDBD_HT-SELEX 		0.758 0.797
KLF2
M10210_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$LKLF_Q3 		0.758 0.797
KLF2
M10211_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$LKLF_Q6 		0.758 0.797
KLF2
M04456_2.00 		Homo sapiens
NVCCMCRCCCN
NGGGYGKGGBN		 SELEX
Yin et al.(2017)
KLF2_eDBD_Methyl-HT-SELEX 		0.758 0.797
Klf1
M08099_2.00 		Mus musculus
NRCCACACCCW
WGGGTGTGGYN		 ChIP-seq
Mathelier et al.(2014)
MA0493.1 		0.758 0.768
Klf1
M09008_2.00 		Mus musculus
MVMNSCCMCRCCCH
DGGGYGKGGSNKBK		 Misc
Kulakovskiy et al.(2013)
KLF1_MOUSE.H11MO.0.A 		0.758 0.768
Klf1
M09516_2.00 		Mus musculus
DRCCACACCCWN
NWGGGTGTGGYH		 Misc
Heinz et al.(2010)
Erythrocyte-Klf1_GSE20478 		0.758 0.768
For this family, TFs with SR scores > 0.755 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00787_2.00 C2H2 ZF 16 40
M00787_2.00 C2H2 ZF 46 70
M00787_2.00 C2H2 ZF 76 98

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000094844 C2H2 ZF 317 341
ENSMUSP00000094844 C2H2 ZF 347 371
ENSMUSP00000094844 C2H2 ZF 377 399

Links

Other C2H2 ZF family TFs
Other Mus musculus TFs

735 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
AAEL014670 Aedes aegypti AAEL014670 I
ACHR008952 Anopheles christyi ACHR008952 I
ACOM033640 Anopheles coluzzii ACOM033640 N
ACYPI001652 Acyrthosiphon pisum ACYPI001652 N
AEPI008594 Anopheles epiroticus AEPI008594 I
AFAF008476 Anopheles farauti AFAF008476 N
AGAP000512 Anopheles gambiae AGAP000512 I
Alligator_sinensis_CCG011289.1 Alligator sinensis Alligator_sinensis_CCG011289.1 I
Alligator_sinensis_CCG020461.1 Alligator sinensis Alligator_sinensis_CCG020461.1 I
ALUE_0001723701 Ascaris lumbricoides ALUE_0001723701 I
AMAM017211 Anopheles maculatus AMAM017211 I
AMEC001670 Anopheles melas AMEC001670 I
AMEM013717 Anopheles merus AMEM013717 I
Aqu1.216869 Amphimedon queenslandica Aqu1.216869 I
ASTEI04517 Anopheles stephensi ASTEI04517 I
A_05340 Schistosoma haematobium A_05340 I
BGIBMGA001129 Bombyx mori BGIBMGA001129 I
Bm11328 Brugia malayi Bm11328 I
CBG02541 Caenorhabditis briggsae CBG02541 I
CLEC025393 Cimex lectularius CLEC025393 I
CPIJ013490 Culex quinquefasciatus CPIJ013490 I
CpipJ_CPIJ013490 Culex pipiens CpipJ_CPIJ013490 I
D918_02241 Trichuris suis D918_02241 I
ECANG7_01760 Echinococcus canadensis ECANG7_01760 I
EFV53558 Trichinella spiralis EFV53558 I
egl-44 Caenorhabditis elegans WBGene00001208 I
ENSCING00000019408 Ciona intestinalis ENSCING00000019408 I
ENSCSAVG00000007634 Ciona savignyi ENSCSAVG00000007634 I
ENSFALG00000003635 Ficedula albicollis ENSFALG00000003635 I
ENSGMOG00000015271 Gadus morhua ENSGMOG00000015271 I
ENSLACG00000016444 Latimeria chalumnae ENSLACG00000016444 I
ENSLOCG00000009736 Lepisosteus oculatus ENSLOCG00000009736 I
ENSNLEG00000017672 Nomascus leucogenys ENSNLEG00000017672 N
ENSP00000355332 Macaca fascicularis ENSP00000355332 N
ENSPFOG00000003170 Poecilia formosa ENSPFOG00000003170 I
ENSPFOG00000013997 Poecilia formosa ENSPFOG00000013997 I
ENSPPYG00000003475 Pongo abelii ENSPPYG00000003475 I
ENSPSIG00000006176 Pelodiscus sinensis ENSPSIG00000006176 I
ENSTSYG00000001514 Tarsius syrichta ENSTSYG00000001514 N
e_gw.291.69.1 Branchiostoma floridae e_gw.291.69.1 I
GA21152 Drosophila pseudoobscura FBgn0081140 I
GE17227 Drosophila yakuba FBgn0234705 I
GF20188 Drosophila ananassae FBgn0097195 I
GG17919 Drosophila erecta FBgn0110139 I
GH12522 Drosophila grimshawi FBgn0120001 I
GI14876 Drosophila mojavensis FBgn0137627 I
GJ19539 Drosophila virilis FBgn0206682 I
GM22588 Drosophila sechellia FBgn0177458 I
HelroG146479 Helobdella robusta HelroG146479 I
HHAL001589-PA Halyomorpha halys HHAL001589-PA I
L798_06691 Zootermopsis nevadensis L798_06691 N
LCUP007338 Lucilia cuprina LCUP007338 I
MDOA005382 Musca domestica MDOA005382 I
NEMVEDRAFT_v1g86806 Nematostella vectensis NEMVEDRAFT_v1g86806 I
NV15824 Nasonia vitripennis NV15824 N
OFLC_0000413701 Onchocerca flexuosa OFLC_0000413701 I
PPAI001408 Phlebotomus papatasi PPAI001408 I
Pvit_05988 Pogona vitticeps Pvit_05988 I
sd Drosophila melanogaster FBgn0003345 D
SMAR011013 Strigamia maritima SMAR011013 I
Tead1 Rattus norvegicus ENSRNOG00000015488 I
TEAD1 Tursiops truncatus ENSTTRG00000006621 N
TEAD1 Canis familiaris ENSCAFG00000007976 I
TEAD1 Callithrix jacchus ENSCJAG00000010263 I
TEAD1 Equus caballus ENSECAG00000008332 I
TEAD1 Homo sapiens ENSG00000187079 D
TEAD1 Gorilla gorilla ENSGGOG00000003412 N
TEAD1 Microcebus murinus ENSMICG00000007178 I
TEAD1 Macaca mulatta ENSMMUG00000010875 N
Tead1 Mus musculus ENSMUSG00000055320 D
TEAD1 Oryctolagus cuniculus ENSOCUG00000007955 I
TEAD1 Pan troglodytes ENSPTRG00000039896 N
TEAD1 Pteropus vampyrus ENSPVAG00000001503 I
tead1a Danio rerio ENSDARG00000028159 I
tead1a Takifugu rubripes ENSTRUG00000005940 I
tead1b Takifugu rubripes ENSTRUG00000017473 N
tead1b Danio rerio ENSDARG00000059483 I
tead1b Tetraodon nigroviridis ENSTNIG00000009360 N
tead1b Gasterosteus aculeatus ENSGACG00000015715 I
TEAD3 Pan troglodytes ENSPTRG00000018086 I
TEAD3 Canis familiaris ENSCAFG00000001326 I
TEAD3 Tursiops truncatus ENSTTRG00000009434 I
Tead3 Dipodomys ordii ENSDORG00000010798 I
TEAD3 Equus caballus ENSECAG00000015056 I
TEAD3 Loxodonta africana ENSLAFG00000014818 I
TEAD3 Microcebus murinus ENSMICG00000000029 I
TEAD3 Taeniopygia guttata ENSTGUG00000001691 I
TEAD3 Macaca mulatta ENSMMUG00000015909 I
TEAD3 Pteropus vampyrus ENSPVAG00000002764 I
TEAD3 Otolemur garnettii ENSOGAG00000002943 I
tead3a Gasterosteus aculeatus ENSGACG00000009758 I
tead3a Takifugu rubripes ENSTRUG00000011546 I
TEAD4 Meleagris gallopavo ENSMGAG00000013910 I
TEAD4 Homo sapiens ENSG00000197905 D
TEAD4 Takifugu rubripes ENSTRUG00000016489 I
Tead4 Mus musculus ENSMUSG00000030353 D
TEAD4 Oryzias latipes ENSORLG00000002553 I
TsM_000210300 Taenia solium TsM_000210300 I
YQE_09490 Dendroctonus ponderosae YQE_09490 I