SMU15000713 (Schmidtea mediterranea)
E2F

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF02319 (E2F_TDP) IPR003316 SMU15000713 T174072_2.00 Misc (2018-Jan-19)

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
E2F4
M02961_2.00 		Homo sapiens
AATGGCGCCAAA
TTTGGCGCCATT		 SELEX
Jolma et al.(2013)
E2F4_1 		0.831 0.831
E2F4
M02962_2.00 		Homo sapiens
TTTGGCGCCAAA
TTTGGCGCCAAA		 SELEX
Jolma et al.(2013)
E2F4_2 		0.831 0.831
E2F4
M04707_2.00 		Homo sapiens
NWWKGGCGCCAAAW
WTTTGGCGCCMWWN		 SELEX
Yin et al.(2017)
E2F4_eDBD_HT-SELEX 		0.831 0.831
E2F4
M08109_2.00 		Homo sapiens
NSGCGGGARVN
NBYTCCCGCSN		 ChIP-seq
Mathelier et al.(2014)
MA0470.1 		0.831 0.831
E2F4
M07942_2.00 		Homo sapiens
SGCGSGARDNNBNVN
NBNVNNHYTCSCGCS		 ChIP-seq
Gerstein et al.(2012)
HeLa-S3_E2F4_UCD 		0.831 0.831
E2F4
M07943_2.00 		Homo sapiens
SGCGGGARDNNBVVN
NBBVNNHYTCCCGCS		 ChIP-seq
Gerstein et al.(2012)
K562b_E2F4_UCD 		0.831 0.831
E2F4
M09036_2.00 		Homo sapiens
VDRGGCGGGRVND
HNBYCCCGCCYHB		 Misc
Kulakovskiy et al.(2013)
E2F4_HUMAN.H11MO.0.A 		0.831 0.831
E2f4
M09037_2.00 		Mus musculus
NRDDGGCGGGRMNN
NNKYCCCGCCHHYN		 Misc
Kulakovskiy et al.(2013)
E2F4_MOUSE.H11MO.0.A 		0.831 0.831
E2F4
M09524_2.00 		Homo sapiens
VGCGSGAADH
DHTTCSCGCB		 Misc
Heinz et al.(2010)
K562-E2F4_GSE31477 		0.831 0.831
E2F4
M10457_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F4_05 		0.831 0.831
E2F4
M10458_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F4_Q3 		0.831 0.831
E2F4
M10459_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F4_Q6 		0.831 0.831
E2f5
M09042_2.00 		Mus musculus
NGCGCSAAAN
NTTTSGCGCN		 Misc
Kulakovskiy et al.(2013)
E2F5_MOUSE.H11MO.0.B 		0.815 0.815
ENSACAG00000013716
M01960_2.00 		Anolis carolinensis
HNVGCGCBND
HNVGCGCBND		 PBM
Weirauch et al.(2014)
pTH9221 		0.723 0.723
E2F2
M01961_2.00 		Homo sapiens
DNSGCGCSNH
DNSGCGCSNH		 PBM
Weirauch et al.(2014)
pTH9195 		0.708 0.708
E2f2
M00154_2.00 		Mus musculus
NDNNGCGSBN
NVSCGCNNHN		 PBM
Badis et al.(2009)
E2F2_1022 		0.708 0.708
E2F2
M01963_2.00 		Tupaia belangeri
WDVGCGCBHW
WDVGCGCBHW		 PBM
Weirauch et al.(2014)
pTH9291 		0.708 0.708
E2F3
M01964_2.00 		Taeniopygia guttata
NNSGCGCGMN
NKCGCGCSNN		 PBM
Weirauch et al.(2014)
pTH9288 		0.708 0.708
e_gw1.38.2.1
M01968_2.00 		Physcomitrella patens
NSGCGCBHHN
NDDVGCGCSN		 PBM
Weirauch et al.(2014)
pTH5707 		0.708 0.708
estExt_gwp_gw1.C_220046
M01225_2.00 		Physcomitrella patens
VGCGCBHHNN
NNDDVGCGCB		 PBM
Lambert et al.(2019)
pTH9809 		0.708 0.708
E2F2
M02949_2.00 		Homo sapiens
AAAAATGGCGCCAAAAWD
HWTTTTGGCGCCATTTTT		 SELEX
Jolma et al.(2013)
E2F2_1 		0.708 0.708
E2F2
M02950_2.00 		Homo sapiens
VDTTTTGGCGCCAAAAHN
NDTTTTGGCGCCAAAAHB		 SELEX
Jolma et al.(2013)
E2F2_2 		0.708 0.708
E2F2
M02951_2.00 		Homo sapiens
AAAWWGGCGCCAWTTT
AAAWTGGCGCCWWTTT		 SELEX
Jolma et al.(2013)
E2F2_3 		0.708 0.708
E2F2
M04696_2.00 		Homo sapiens
GCGCGCGCSYW
WRSGCGCGCGC		 SELEX
Yin et al.(2017)
E2F2_eDBD_HT-SELEX_1 		0.708 0.708
E2F2
M04697_2.00 		Homo sapiens
NDWWDGGCGCCWWHWN
NWDWWGGCGCCHWWHN		 SELEX
Yin et al.(2017)
E2F2_eDBD_HT-SELEX_2 		0.708 0.708
E2FC
M06870_2.00 		Arabidopsis thaliana
AWDDDGGCGCCAAAR
YTTTGGCGCCHHHWT		 Dap-seq
OMalley et al.(2016)
E2FC_col_a 		0.708 0.708
E2F2
M09029_2.00 		Homo sapiens
GGCGCGMAWC
GWTKCGCGCC		 Misc
Kulakovskiy et al.(2013)
E2F2_HUMAN.H11MO.0.B 		0.708 0.708
E2f2
M09039_2.00 		Mus musculus
GGCGCGMAWC
GWTKCGCGCC		 Misc
Kulakovskiy et al.(2013)
E2F2_MOUSE.H11MO.0.B 		0.708 0.708
E2F2
M04698_2.00 		Homo sapiens
SGBGSGCGCGS
SCGCGCSCVCS		 SELEX
Yin et al.(2017)
E2F2_eDBD_Methyl-HT-SELEX_1 		0.708 0.708
E2F2
M04699_2.00 		Homo sapiens
DWWWDGGCGCCAAAWH
DWTTTGGCGCCHWWWH		 SELEX
Yin et al.(2017)
E2F2_eDBD_Methyl-HT-SELEX_2 		0.708 0.708
E2f3
M00153_2.00 		Mus musculus
NNNNGCGSNN
NNSCGCNNNN		 PBM
Badis et al.(2009)
E2F3_3752 		0.692 0.692
ENSOANG00000014967
M01962_2.00 		Ornithorhynchus anatinus
NDSGCGCSHN
NDSGCGCSHN		 PBM
Weirauch et al.(2014)
pTH9382 		0.692 0.692
E2F3
M02956_2.00 		Homo sapiens
RAAAAKGGCGCCAAAANN
NNTTTTGGCGCCMTTTTY		 SELEX
Jolma et al.(2013)
E2F3_1 		0.692 0.692
E2F3
M02957_2.00 		Homo sapiens
DAAAADGGCGCCMWWTTY
RAAWWKGGCGCCHTTTTH		 SELEX
Jolma et al.(2013)
E2F3_2 		0.692 0.692
E2F3
M02958_2.00 		Homo sapiens
NDTTTTGGCGCCAAAABH
DVTTTTGGCGCCAAAAHN		 SELEX
Jolma et al.(2013)
E2F3_3 		0.692 0.692
E2F3
M04701_2.00 		Homo sapiens
DWTTTGGCGCCAAAWH
DWTTTGGCGCCAAAWH		 SELEX
Yin et al.(2017)
E2F3_eDBD_HT-SELEX 		0.692 0.692
E2FA
M06871_2.00 		Arabidopsis thaliana
NDDDGGCGCCAWWW
WWWTGGCGCCHHHN		 Dap-seq
OMalley et al.(2016)
E2FA_col_a 		0.692 0.692
E2FA
M06872_2.00 		Arabidopsis thaliana
DDWDGGCGCCAWAD
HTWTGGCGCCHWHH		 Dap-seq
OMalley et al.(2016)
E2FA_colamp_a 		0.692 0.692
E2FA
M08106_2.00 		Arabidopsis thaliana
NVGCGCCAHN
NDTGGCGCBN		 ChIP-seq
Mathelier et al.(2014)
MA1414.1 		0.692 0.692
E2F3
M09031_2.00 		Homo sapiens
NDGGCGGGAAR
YTTCCCGCCHN		 Misc
Kulakovskiy et al.(2013)
E2F3_HUMAN.H11MO.0.A 		0.692 0.692
E2f3
M09038_2.00 		Mus musculus
DSGCGGGARV
BYTCCCGCSH		 Misc
Kulakovskiy et al.(2013)
E2F3_MOUSE.H11MO.0.A 		0.692 0.692
E2F3
M10454_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F1_Q6_01 		0.692 0.692
E2F3
M10455_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F3_Q6 		0.692 0.692
E2F3
M04702_2.00 		Homo sapiens
DTTTTGGCGCCAAAAH
DTTTTGGCGCCAAAAH		 SELEX
Yin et al.(2017)
E2F3_eDBD_Methyl-HT-SELEX 		0.692 0.692
efl-1
M08110_2.00 		Caenorhabditis elegans
HNHNSGCGSSAAWWN
NWWTTSSCGCSNDND		 ChIP-seq
Mathelier et al.(2014)
MA0541.1 		0.662 0.662
E2f
M08196_2.00 		Drosophila melanogaster
AAWWBSSCGSCAA
TTGSCGSSVWWTT		 ChIP-seq
Contrino et al.(2012)
Mf10 		0.662 0.662
efl-1
M08197_2.00 		Caenorhabditis elegans
BGCGSSAAWW
WWTTSSCGCV		 ChIP-seq
Contrino et al.(2012)
Mw140 		0.662 0.662
efl-1
M09526_2.00 		Caenorhabditis elegans
WGCAARYGCGCTCYA
TRGAGCGCRYTTGCW		 Misc
Heinz et al.(2010)
cElegans-L1-EFL1_modEncode 		0.662 0.662
E2F1
M02952_2.00 		Homo sapiens
WWDGGCGCCAAW
WTTGGCGCCHWW		 SELEX
Jolma et al.(2013)
E2F1_1 		0.646 0.646
E2F1
M02953_2.00 		Homo sapiens
WWKGGCGCCWWW
WWWGGCGCCMWW		 SELEX
Jolma et al.(2013)
E2F1_2 		0.646 0.646
E2F1
M02954_2.00 		Homo sapiens
WWWKGGCGCCMWWW
WWWKGGCGCCMWWW		 SELEX
Jolma et al.(2013)
E2F1_3 		0.646 0.646
E2F1
M02955_2.00 		Homo sapiens
AAWKGGCGCCAWTW
WAWTGGCGCCMWTT		 SELEX
Jolma et al.(2013)
E2F1_4 		0.646 0.646
E2F1
M04700_2.00 		Homo sapiens
NWWWDGGCGCCAAAWH
DWTTTGGCGCCHWWWN		 SELEX
Yin et al.(2017)
E2F1_FL_HT-SELEX 		0.646 0.646
E2F1
M07938_2.00 		Homo sapiens
VRRVNRVGCGSGMDS
SHKCSCGCBYNBYYB		 ChIP-seq
Gerstein et al.(2012)
HeLa-S3_E2F1_UCD 		0.646 0.646
E2F1
M09030_2.00 		Homo sapiens
NVNDGGCGGGARVN
NBYTCCCGCCHNBN		 Misc
Kulakovskiy et al.(2013)
E2F1_HUMAN.H11MO.0.A 		0.646 0.646
E2f1
M09041_2.00 		Mus musculus
NDDGGCGGGRVN
NBYCCCGCCHHN		 Misc
Kulakovskiy et al.(2013)
E2F1_MOUSE.H11MO.0.A 		0.646 0.646
E2F1
M09521_2.00 		Homo sapiens
NNGGCGGGAA
TTCCCGCCNN		 Misc
Heinz et al.(2010)
Hela-E2F1_GSE22478 		0.646 0.646
E2F1
M10444_2.00 		Homo sapiens
THVGCGCGAAAAHKR
YMDTTTTCGCGCBDA		 Transfac
Matys et al.(2006)
V$E2F_01 		0.646 0.646
E2F1
M10445_2.00 		Homo sapiens
BHKSGCGCSAAA
TTTSGCGCSMDV		 Transfac
Matys et al.(2006)
V$E2F_03 		0.646 0.646
E2F1
M10446_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F1_01 		0.646 0.646
E2F1
M10447_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F1_02 		0.646 0.646
E2F1
M10448_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F1_Q3_01 		0.646 0.646
E2F1
M10449_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F1_Q3 		0.646 0.646
E2F1
M10450_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F1_Q4_01 		0.646 0.646
E2F1
M10451_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F1_Q4_02 		0.646 0.646
E2F1
M10452_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F1_Q4 		0.646 0.646
E2F1
M10453_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F1_Q6 		0.646 0.646
E2F
M01959_2.00 		Dictyostelium discoideum
NNGSGCGCSHN
NDSGCGCSCNN		 PBM
Weirauch et al.(2014)
pTH5403 		0.585 0.585
GSPATT00020286001
M01965_2.00 		Paramecium tetraurelia
NNSGCGSBN
NVSCGCSNN		 PBM
Weirauch et al.(2014)
pTH5647 		0.585 0.585
E2F6
M08107_2.00 		Homo sapiens
DGGMGGGARVN
NBYTCCCKCCH		 ChIP-seq
Mathelier et al.(2014)
MA0471.1 		0.585 0.585
E2F6
M07939_2.00 		Homo sapiens
NDSGCGGGARV
BYTCCCGCSHN		 ChIP-seq
Gerstein et al.(2012)
HeLa-S3_E2F6_UCD 		0.585 0.585
E2F6
M07940_2.00 		Homo sapiens
NDVGCGGGARV
BYTCCCGCBHN		 ChIP-seq
Gerstein et al.(2012)
K562b_E2F6_UCD 		0.585 0.585
E2F6
M07941_2.00 		Homo sapiens
NDSGCGGGARV
BYTCCCGCSHN		 ChIP-seq
Gerstein et al.(2012)
K562_E2F6_HudsonAlpha 		0.585 0.585
E2F6
M09034_2.00 		Homo sapiens
NRGGMGGGARRNN
NNYYTCCCKCCYN		 Misc
Kulakovskiy et al.(2013)
E2F6_HUMAN.H11MO.0.A 		0.585 0.585
E2f6
M09043_2.00 		Mus musculus
NDGGCGGGARVV
BBYTCCCGCCHN		 Misc
Kulakovskiy et al.(2013)
E2F6_MOUSE.H11MO.0.A 		0.585 0.585
E2F6
M09523_2.00 		Homo sapiens
VGCGGGARNN
NNYTCCCGCB		 Misc
Heinz et al.(2010)
Hela-E2F6_GSE31477 		0.585 0.585
E2F6
M10456_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F6_01 		0.585 0.585
estExt_gwp_GeneWisePlus.C_Chr_02.00010270
M01969_2.00 		Ostreococcus tauri
HRVGCGCCNN
NNGGCGCBYD		 PBM
Weirauch et al.(2014)
pTH5701 		0.523 0.523
efl-2
M01966_2.00 		Caenorhabditis elegans
NDBGCGSBNN
NNVSCGCVHN		 PBM
Weirauch et al.(2014)
pTH5916 		0.462 0.462
efl-2
M00662_2.00 		Caenorhabditis elegans
NSGCGSNNDN
NHNNSCGCSN		 PBM
Narasimhan et al.(2015)
pTH9173 		0.462 0.462
For this family, TFs with SR scores > 0.429 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
SMU15000713 E2F 37 102

Links

Other E2F family TFs
Other Schmidtea mediterranea TFs

1040 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
AAH70718 Xenopus laevis AAH70718 I 0.000
Aan_R007004 Calypte anna Aan_R007004 I 0.000
Aan_R011644 Calypte anna Aan_R011644 I 0.000
Afo_R000236 Aptenodytes forsteri Afo_R000236 I 0.000
Afo_R004692 Aptenodytes forsteri Afo_R004692 I 0.000
Brh_R000160 Buceros rhinoceros Brh_R000160 I 0.000
Brh_R011012 Buceros rhinoceros Brh_R011012 I 0.000
Cmyd_10012301 Chelonia mydas Cmyd_10012301 I 0.000
Cmyd_10016351 Chelonia mydas Cmyd_10016351 I 0.000
ENSAMEG00000019750 Ailuropoda melanoleuca ENSAMEG00000019750 I 0.000
ENSAMXG00000002993 Astyanax mexicanus ENSAMXG00000002993 I 0.000
ENSAPLG00000002367 Anas platyrhynchos ENSAPLG00000002367 I 0.000
ENSBTAP00000000497-D1 Bos grunniens ENSBTAP00000000497-D1 I 0.000
ENSCPOG00000023254 Cavia porcellus ENSCPOG00000023254 I 0.000
ENSDORG00000000569 Dipodomys ordii ENSDORG00000000569 I 0.000
ENSFALG00000011473 Ficedula albicollis ENSFALG00000011473 I 0.000
ENSFALG00000014898 Ficedula albicollis ENSFALG00000014898 I 0.000
ENSFCAG00000026731 Felis catus ENSFCAG00000026731 I 0.000
ENSGMOG00000018718 Gadus morhua ENSGMOG00000018718 I 0.000
ENSLACG00000009889 Latimeria chalumnae ENSLACG00000009889 I 0.000
ENSLOCG00000017349 Lepisosteus oculatus ENSLOCG00000017349 I 0.000
ENSMEUG00000009369 Macropus eugenii ENSMEUG00000009369 I 0.000
ENSMPUG00000015734 Mustela putorius furo ENSMPUG00000015734 I 0.000
ENSNLEG00000003981 Nomascus leucogenys ENSNLEG00000003981 I 0.000
ENSOARG00000005939 Ovis aries ENSOARG00000005939 I 0.000
ENSONIG00000000862 Oreochromis niloticus ENSONIG00000000862 I 0.000
ENSP00000351539 Macaca fascicularis ENSP00000351539 I 0.000
ENSPANG00000021934 Papio anubis ENSPANG00000021934 I 0.000
ENSPFOG00000022080 Poecilia formosa ENSPFOG00000022080 I 0.000
ENSPPYG00000000059 Pongo abelii ENSPPYG00000000059 I 0.000
ENSPSIG00000000487 Pelodiscus sinensis ENSPSIG00000000487 I 0.000
ENSSHAG00000008659 Sarcophilus harrisii ENSSHAG00000008659 I 0.000
ENSSSCG00000030070 Sus scrofa ENSSSCG00000030070 I 0.000
ENSSTOG00000004290 Ictidomys tridecemlineatus ENSSTOG00000004290 I 0.000
ENSTSYG00000004607 Tarsius syrichta ENSTSYG00000004607 I 0.000
ENSXMAG00000018241 Xiphophorus maculatus ENSXMAG00000018241 I 0.000
Gfo_R006792 Geospiza fortis Gfo_R006792 I 0.000
Gfo_R011040 Geospiza fortis Gfo_R011040 I 0.000
Myotis_brandtii_ZNF238_10003031 Myotis brandtii Myotis_brandtii_ZNF238_10003031 I 0.000
Pvit_01078 Pogona vitticeps Pvit_01078 I 0.000
ZBTB18 Tursiops truncatus ENSTTRG00000000615 I 0.000
zbtb18 Takifugu rubripes ENSTRUG00000000952 I 0.000
zbtb18 Xenopus tropicalis XB-GENE-1003542 I 0.000
zbtb18 Tetraodon nigroviridis ENSTNIG00000000430 I 0.000
ZBTB18 Taeniopygia guttata ENSTGUG00000008247 I 0.000
zbtb18 Oryzias latipes ENSORLG00000004823 I 0.000
ZBTB18 Sorex araneus ENSSARG00000002984 I 0.000
ZBTB18 Bos taurus ENSBTAG00000000385 I 0.000
ZBTB18 Callithrix jacchus ENSCJAG00000017087 I 0.000
zbtb18 Danio rerio ENSDARG00000028228 I 0.000
ZBTB18 Dasypus novemcinctus ENSDNOG00000009334 I 0.000
ZBTB18 Equus caballus ENSECAG00000018829 I 0.000
ZBTB18 Erinaceus europaeus ENSEEUG00000014181 I 0.000
ZBTB18 Homo sapiens ENSG00000179456 D 0.000
zbtb18 Gasterosteus aculeatus ENSGACG00000010518 I 0.000
ZBTB18 Gallus gallus ENSGALG00000010705 I 0.000
ZBTB18 Gorilla gorilla ENSGGOG00000028442 I 0.000
ZBTB18 Loxodonta africana ENSLAFG00000002879 I 0.000
ZBTB18 Microcebus murinus ENSMICG00000007600 I 0.000
ZBTB18 Myotis lucifugus ENSMLUG00000011285 I 0.000
ZBTB18 Macaca mulatta ENSMMUG00000015664 I 0.000
ZBTB18 Monodelphis domestica ENSMODG00000006570 I 0.000
Zbtb18 Mus musculus ENSMUSG00000063659 I 0.000
ZBTB18 Ornithorhynchus anatinus ENSOANG00000010257 I 0.000
ZBTB18 Oryctolagus cuniculus ENSOCUG00000007968 I 0.000
ZBTB18 Otolemur garnettii ENSOGAG00000013580 I 0.000
ZBTB18 Anolis carolinensis ENSACAG00000004296 I 0.000
ZBTB18 Pan troglodytes ENSPTRG00000002175 I 0.000
ZBTB18 Pteropus vampyrus ENSPVAG00000011441 I 0.000
zbtb18.L Xenopus laevis XB-GENE-1003548 I 0.000
Zfp238 Rattus norvegicus ENSRNOG00000004423 I 0.000
znf238.2.L Xenopus laevis XB-GENE-1219070 I 0.000