SIX2 (Erinaceus europaeus)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSEEUG00000004059 T209242_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Six2
M00425_2.00 		Mus musculus
NNAYMYNN
NNRKRTNN		 PBM
Berger et al.(2008)
Six2_2307 		0.867 1.000
SIX2
M05285_2.00 		Homo sapiens
NNYGATACSB
VSGTATCRNN		 SELEX
Yin et al.(2017)
SIX2_eDBD_HT-SELEX 		0.867 1.000
SIX2
M05287_2.00 		Homo sapiens
NSGTRWCRYN
NRYGWYACSN		 SELEX
Yin et al.(2017)
SIX2_FL_HT-SELEX 		0.867 1.000
SIX2
M08133_2.00 		Homo sapiens
NNNTGWAACCTGAKMH
DKMTCAGGTTWCANNN		 ChIP-seq
Mathelier et al.(2014)
MA1119.1 		0.867 1.000
SIX2
M09157_2.00 		Homo sapiens
DGWAAYHHGABMH
DKVTCDDRTTWCH		 Misc
Kulakovskiy et al.(2013)
SIX2_HUMAN.H11MO.0.A 		0.867 1.000
Six2
M09185_2.00 		Mus musculus
DGWAAYHYRABMYB
VRKVTYRDRTTWCH		 Misc
Kulakovskiy et al.(2013)
SIX2_MOUSE.H11MO.0.A 		0.867 1.000
SIX2
M05286_2.00 		Homo sapiens
NBRTATCRNN
NNYGATAYVN		 SELEX
Yin et al.(2017)
SIX2_eDBD_Methyl-HT-SELEX 		0.867 1.000
SIX2
M05288_2.00 		Homo sapiens
VBRTAWCRNN
NNYGWTAYVB		 SELEX
Yin et al.(2017)
SIX2_FL_Methyl-HT-SELEX 		0.867 1.000
so
M02117_2.00 		Drosophila melanogaster
NDATMYNNN
NNNRKATHN		 PBM
Weirauch et al.(2014)
pTH5690 		0.866 0.945
so
M03800_2.00 		Drosophila melanogaster
NYGATAYB
VRTATCRN		 SELEX
Nitta et al.(2015)
so_1 		0.866 0.945
so
M03801_2.00 		Drosophila melanogaster
YKATAYNNNYGATAY
RTATCRNNNRTATMR		 SELEX
Nitta et al.(2015)
so_2 		0.866 0.945
so
M03802_2.00 		Drosophila melanogaster
YGATACGTATCR
YGATACGTATCR		 SELEX
Nitta et al.(2015)
so_3 		0.866 0.945
so
M03803_2.00 		Drosophila melanogaster
RTATCRYGATAC
GTATCRYGATAY		 SELEX
Nitta et al.(2015)
so_4 		0.866 0.945
so
M06497_2.00 		Drosophila melanogaster
TGATAC
GTATCA		 B1H
Mathelier et al.(2014)
MA0246.1 		0.866 0.945
so
M06268_2.00 		Drosophila melanogaster
NRTGATA
TATCAYN		 B1H
Zhu et al.(2011)
So_Cell_FBgn0003460 		0.866 0.945
so
M06269_2.00 		Drosophila melanogaster
NNNTGATA
TATCANNN		 B1H
Zhu et al.(2011)
So_SOLEXA_FBgn0003460 		0.866 0.945
Six1
M00512_2.00 		Mus musculus
NNDATMYNNN
NNNRKATHNN		 PBM
Berger et al.(2008)
Six1_0935 		0.865 0.982
SIX1
M05094_2.00 		Homo sapiens
NNYGATACVB
VBGTATCRNN		 SELEX
Yin et al.(2017)
SIX1_eDBD_HT-SELEX 		0.865 0.982
SIX1
M05096_2.00 		Homo sapiens
NNYGATAYVB
VBRTATCRNN		 SELEX
Yin et al.(2017)
SIX1_FL_HT-SELEX 		0.865 0.982
SIX1
M08130_2.00 		Homo sapiens
GWAACCTGANM
KNTCAGGTTWC		 ChIP-seq
Mathelier et al.(2014)
MA1118.1 		0.865 0.982
SIX1
M09142_2.00 		Homo sapiens
DGWAAYHTGABMYN
NRKVTCADRTTWCH		 Misc
Kulakovskiy et al.(2013)
SIX1_HUMAN.H11MO.0.A 		0.865 0.982
Six1
M09579_2.00 		Mus musculus
GWAAYHTGABMH
DKVTCADRTTWC		 Misc
Heinz et al.(2010)
Myoblast-Six1_GSE20150 		0.865 0.982
SIX1
M10684_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX1_Q3_01 		0.865 0.982
SIX1
M10685_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX1_Q3 		0.865 0.982
SIX1
M05095_2.00 		Homo sapiens
NNYGATABNB
VNVTATCRNN		 SELEX
Yin et al.(2017)
SIX1_eDBD_Methyl-HT-SELEX 		0.865 0.982
SIX1
M05097_2.00 		Homo sapiens
NNYGATAYSB
VSRTATCRNN		 SELEX
Yin et al.(2017)
SIX1_FL_Methyl-HT-SELEX 		0.865 0.982
Six4
M00461_2.00 		Mus musculus
NNKABMHNN
NNDKVTMNN		 PBM
Berger et al.(2008)
Six4_2860 		0.708 0.709
SIX4
M04939_2.00 		Homo sapiens
NVYGATACVB
VBGTATCRBN		 SELEX
Yin et al.(2017)
SIX4_eDBD_HT-SELEX 		0.708 0.709
Six4
M09198_2.00 		Mus musculus
DGDAABHNSASNNN
NNNSTSNDVTTHCH		 Misc
Kulakovskiy et al.(2013)
SIX4_MOUSE.H11MO.0.C 		0.708 0.709
SIX4
M10646_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX4_Q3 		0.708 0.709
SIX4
M04940_2.00 		Homo sapiens
NBGTAWCRHN
NDYGWTACVN		 SELEX
Yin et al.(2017)
SIX4_eDBD_Methyl-HT-SELEX 		0.708 0.709
Six4
M00563_2.00 		Drosophila melanogaster
NNDANMHNN
NNDKNTHNN		 PBM
Busser et al.(2012a)
Six4 		0.708 0.673
Six4
M06530_2.00 		Drosophila melanogaster
TGABAC
GTVTCA		 B1H
Mathelier et al.(2014)
MA0204.1 		0.708 0.673
Six4
M06334_2.00 		Drosophila melanogaster
WDDTGABAC
GTVTCAHHW		 B1H
Zhu et al.(2011)
Six4_Cell_FBgn0027364 		0.708 0.673
Six4
M06335_2.00 		Drosophila melanogaster
NTGAKACB
VGTMTCAN		 B1H
Zhu et al.(2011)
Six4_SOLEXA_2_FBgn0027364 		0.708 0.673
Six4
M06336_2.00 		Drosophila melanogaster
NNNTGABA
TVTCANNN		 B1H
Zhu et al.(2011)
Six4_SOLEXA_FBgn0027364 		0.708 0.673
SIX5
M08208_2.00 		Homo sapiens
GARWTGTAGT
ACTACAWYTC		 ChIP-seq
Contrino et al.(2012)
Mv121 		0.708 0.655
SIX5
M08209_2.00 		Homo sapiens
GGAGTTGT
ACAACTCC		 ChIP-seq
Contrino et al.(2012)
Mv123 		0.708 0.655
SIX5
M10738_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX5_01 		0.708 0.655
SIX5
M10739_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX5_02 		0.708 0.655
ceh-34
M00672_2.00 		Caenorhabditis elegans
NNNRDAWNNN
NNNWTHYNNN		 PBM
Narasimhan et al.(2015)
pTH9708 		0.664 0.618
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSEEUP00000003680 Homeodomain 127 181

Links

Other Homeodomain family TFs
Other Erinaceus europaeus TFs

540 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Aan_R015482 Calypte anna Aan_R015482 N
Afo_R013969 Aptenodytes forsteri Afo_R013969 N
Alligator_sinensis_CCG011037.1 Alligator sinensis Alligator_sinensis_CCG011037.1 N
Brh_R002265 Buceros rhinoceros Brh_R002265 N
ENSAMEG00000007556 Ailuropoda melanoleuca ENSAMEG00000007556 N
ENSBTAP00000024222-D1 Bos grunniens ENSBTAP00000024222-D1 N
ENSCPOG00000020832 Cavia porcellus ENSCPOG00000020832 N
ENSCSAG00000001058 Chlorocebus sabaeus ENSCSAG00000001058 N
ENSFALG00000000603 Ficedula albicollis ENSFALG00000000603 N
ENSGALG00000003420 Gallus gallus ENSGALG00000003420 N
ENSMEUG00000013710 Macropus eugenii ENSMEUG00000013710 N
ENSMPUG00000015223 Mustela putorius furo ENSMPUG00000015223 N
ENSNLEG00000002769 Nomascus leucogenys ENSNLEG00000002769 N
ENSOARG00000020930 Ovis aries ENSOARG00000020930 N
ENSPANG00000019096 Papio anubis ENSPANG00000019096 N
ENSPPYG00000001590 Pongo abelii ENSPPYG00000001590 N
ENSPSIG00000008472 Pelodiscus sinensis ENSPSIG00000008472 N
ENSSHAG00000010423 Sarcophilus harrisii ENSSHAG00000010423 N
ENSSTOG00000024103 Ictidomys tridecemlineatus ENSSTOG00000024103 N
ENSTSYG00000009437 Tarsius syrichta ENSTSYG00000009437 N
Gfo_R011646 Geospiza fortis Gfo_R011646 N
Myotis_brandtii_ZBTB8A_10012393 Myotis brandtii Myotis_brandtii_ZBTB8A_10012393 N
Ogr05994 Ophisaurus gracilis Ogr05994 N
Pvit_17720 Pogona vitticeps Pvit_17720 N
Tal_R009236 Tyto alba Tal_R009236 N
ZBTB8A Taeniopygia guttata ENSTGUG00000001373 N
ZBTB8A Anolis carolinensis ENSACAG00000004819 N
ZBTB8A Bos taurus ENSBTAG00000018199 N
ZBTB8A Canis familiaris ENSCAFG00000023779 N
ZBTB8A Choloepus hoffmanni ENSCHOG00000004051 N
ZBTB8A Callithrix jacchus ENSCJAG00000001003 N
ZBTB8A Dasypus novemcinctus ENSDNOG00000032935 N
Zbtb8a Dipodomys ordii ENSDORG00000007027 N
ZBTB8A Equus caballus ENSECAG00000023392 N
ZBTB8A Felis catus ENSFCAG00000027580 N
ZBTB8A Homo sapiens ENSG00000160062 N
ZBTB8A Vicugna pacos ENSVPAG00000011873 N
ZBTB8A Tursiops truncatus ENSTTRG00000014967 N
ZBTB8A Loxodonta africana ENSLAFG00000031979 N
ZBTB8A Oryctolagus cuniculus ENSOCUG00000021621 N
ZBTB8A Meleagris gallopavo ENSMGAG00000004949 N
ZBTB8A Sus scrofa ENSSSCG00000021457 N
ZBTB8A Myotis lucifugus ENSMLUG00000023002 N
Zbtb8a Rattus norvegicus ENSRNOG00000008300 N
ZBTB8A Pteropus vampyrus ENSPVAG00000010978 N
ZBTB8A Pan troglodytes ENSPTRG00000034505 N
ZBTB8A Monodelphis domestica ENSMODG00000017424 N
Zbtb8a Mus musculus ENSMUSG00000028807 N
ZBTB8A Procavia capensis ENSPCAG00000013857 N
ZBTB8A Ornithorhynchus anatinus ENSOANG00000001191 N
ZBTB8A Ochotona princeps ENSOPRG00000018275 N
ZBTB8A Otolemur garnettii ENSOGAG00000028328 N