CIS-BP Database: Catalog of Inferred Sequence Binding Preferences

TF Information

pknox2 *(Takifugu rubripes)* Homeodomain
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF00046 (Homeobox)	IPR001356	ENSTRUG00000003012	T216627_2.00	Ensembl (2018-Dec-8)	Link out
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
Pknox2 M00468_2.00	Mus musculus	NNNGACRNNN	NNNYGTCNNN	PBM Berger et al.(2008) Pknox2_3077	0.867	1.000
PKNOX2 M03195_2.00	Homo sapiens	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) PKNOX2_1	0.867	1.000
Pknox2 M03270_2.00	Mus musculus	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) Pknox2_1	0.867	1.000
PKNOX2 M05246_2.00	Homo sapiens	TGACABVTGTCA	TGACABVTGTCA	SELEX Yin et al.(2017) PKNOX2_eDBD_HT-SELEX	0.867	1.000
PKNOX2 M05247_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) PKNOX2_eDBD_Methyl-HT-SELEX	0.867	1.000
Pknox1 M00399_2.00	Mus musculus	HGACRNNN	NNNYGTCD	PBM Berger et al.(2008) Pknox1_2364	0.867	0.964
PKNOX1 M03178_2.00	Homo sapiens	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) PKNOX1_1	0.867	0.964
PKNOX1 M05206_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) PKNOX1_eDBD_HT-SELEX	0.867	0.964
PKNOX1 M05208_2.00	Homo sapiens	TGACAGCTGTCA	TGACAGCTGTCA	SELEX Yin et al.(2017) PKNOX1_FL_HT-SELEX	0.867	0.964
PKNOX1 M09150_2.00	Homo sapiens	TGABTGRCRGV	BCYGYCAVTCA	Misc Kulakovskiy et al.(2013) PKNX1_HUMAN.H11MO.0.B	0.867	0.964
Pknox1 M09175_2.00	Mus musculus	TGABTGRCRGV	BCYGYCAVTCA	Misc Kulakovskiy et al.(2013) PKNX1_MOUSE.H11MO.0.A	0.867	0.964
PKNOX1 M10712_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PREP1_Q3	0.867	0.964
PKNOX1 M05207_2.00	Homo sapiens	YGWCASSTGWCR	YGWCASSTGWCR	SELEX Yin et al.(2017) PKNOX1_eDBD_Methyl-HT-SELEX	0.867	0.964
PKNOX1 M05209_2.00	Homo sapiens	TGACABVTGTCA	TGACABVTGTCA	SELEX Yin et al.(2017) PKNOX1_FL_Methyl-HT-SELEX	0.867	0.964
Meis1 M00407_2.00	Mus musculus	NTGACADNN	NNHTGTCAN	PBM Berger et al.(2008) Meis1_2335	0.751	0.727
Meis2 M00437_2.00	Mus musculus	NTGACANNN	NNNTGTCAN	PBM Berger et al.(2008) Mrg1_2246	0.751	0.727
Meis3 M00488_2.00	Mus musculus	NTGACANNN	NNNTGTCAN	PBM Berger et al.(2008) Mrg2_2302	0.751	0.727
MEIS1 M03165_2.00	Homo sapiens	NTGACAN	NTGTCAN	SELEX Jolma et al.(2013) MEIS1_1	0.751	0.727
MEIS2 M03147_2.00	Homo sapiens	WTGACAGSTGTCAM	KTGACASCTGTCAW	SELEX Jolma et al.(2013) MEIS2_1	0.751	0.727
MEIS2 M03148_2.00	Homo sapiens	DTGACAGS	SCTGTCAH	SELEX Jolma et al.(2013) MEIS2_2	0.751	0.727
Meis2 M03261_2.00	Mus musculus	NTGACAN	NTGTCAN	SELEX Jolma et al.(2013) Meis2_1	0.751	0.727
Meis2 M03262_2.00	Mus musculus	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) Meis2_2	0.751	0.727
Meis3 M03279_2.00	Mus musculus	NTGACAN	NTGTCAN	SELEX Jolma et al.(2013) Meis3_1	0.751	0.727
Meis3 M03280_2.00	Mus musculus	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) Meis3_2	0.751	0.727
MEIS2 M02740_2.00	Homo sapiens	TGACASSTGTC	GACASSTGTCA	SELEX Jolma et al.(2010) MEIS2_dimer	0.751	0.727
MEIS2 M02741_2.00	Homo sapiens	GGACAKNT	ANMTGTCC	SELEX Jolma et al.(2010) MEIS2_monomer	0.751	0.727
MEIS2 M05138_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) MEIS2_eDBD_HT-SELEX	0.751	0.727
MEIS2 M05140_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) MEIS2_FL_HT-SELEX	0.751	0.727
hth M06490_2.00	Drosophila melanogaster	TGACAK	MTGTCA	B1H Mathelier et al.(2014) MA0227.1	0.751	0.727
hth M06252_2.00	Drosophila melanogaster	TGTCA	TGACA	B1H Zhu et al.(2011) Hth_Cell_FBgn0001235	0.751	0.727
hth M06253_2.00	Drosophila melanogaster	NNTGACAD	HTGTCANN	B1H Zhu et al.(2011) hth_SOLEXA_2_FBgn0001235	0.751	0.727
hth M06254_2.00	Drosophila melanogaster	NTGACA	TGTCAN	B1H Zhu et al.(2011) Hth_SOLEXA_FBgn0001235	0.751	0.727
MEIS1 M09148_2.00	Homo sapiens	NTGATTDATDDB	VHHATHAATCAN	Misc Kulakovskiy et al.(2013) MEIS1_HUMAN.H11MO.0.A	0.751	0.727
MEIS2 M09143_2.00	Homo sapiens	HTGACAGBTKTBM	KVAMAVCTGTCAD	Misc Kulakovskiy et al.(2013) MEIS2_HUMAN.H11MO.0.B	0.751	0.727
Meis1 M09178_2.00	Mus musculus	NTGATTDATDDB	VHHATHAATCAN	Misc Kulakovskiy et al.(2013) MEIS1_MOUSE.H11MO.0.A	0.751	0.727
Meis2 M09189_2.00	Mus musculus	HTGACAGBTKTBM	KVAMAVCTGTCAD	Misc Kulakovskiy et al.(2013) MEIS2_MOUSE.H11MO.0.B	0.751	0.727
Meis1 M09568_2.00	Mus musculus	VBTGWCASNN	NNSTGWCAVB	Misc Heinz et al.(2010) MastCells-Meis1_GSE48085	0.751	0.727
MEIS1 M10709_2.00	Homo sapiens	NHNTGACAGNDN	NHNCTGTCANDN	Transfac Matys et al.(2006) V$MEIS1_01	0.751	0.727
MEIS1 M10710_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$MEIS1_06	0.751	0.727
MEIS2 M05139_2.00	Homo sapiens	YGACASSYGHCR	YGDCRSSTGTCR	SELEX Yin et al.(2017) MEIS2_eDBD_Methyl-HT-SELEX	0.751	0.727
MEIS2 M05141_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) MEIS2_FL_Methyl-HT-SELEX	0.751	0.727
unc-62 M02185_2.00	Caenorhabditis elegans	NHDAHANNN	NNNTDTHDN	PBM Weirauch et al.(2014) pTH5781	0.738	0.655
Tgif2 M00521_2.00	Mus musculus	NNTGACANNN	NNNTGTCANN	PBM Berger et al.(2008) Tgif2_3451	0.633	0.527
TGIF2 M03123_2.00	Homo sapiens	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) TGIF2_1	0.633	0.527
TGIF2 M05032_2.00	Homo sapiens	TGACABVTGTCA	TGACABVTGTCA	SELEX Yin et al.(2017) TGIF2_eDBD_HT-SELEX	0.633	0.527
TGIF2 M05034_2.00	Homo sapiens	DTGACANN	NNTGTCAH	SELEX Yin et al.(2017) TGIF2_FL_HT-SELEX	0.633	0.527
TGIF2 M05033_2.00	Homo sapiens	TGWCABVTGWCA	TGWCABVTGWCA	SELEX Yin et al.(2017) TGIF2_eDBD_Methyl-HT-SELEX	0.633	0.527
TGIF2 M05035_2.00	Homo sapiens	DTGACANN	NNTGTCAH	SELEX Yin et al.(2017) TGIF2_FL_Methyl-HT-SELEX	0.633	0.527
Tgif1 M00500_2.00	Mus musculus	NNTGACANNN	NNNTGTCANN	PBM Berger et al.(2008) Tgif1_2342	0.631	0.527
TGIF1 M03223_2.00	Homo sapiens	TGACAGCTGTCA	TGACAGCTGTCA	SELEX Jolma et al.(2013) TGIF1_1	0.631	0.527
TGIF1 M05317_2.00	Homo sapiens	TGACAGSTGTCA	TGACASCTGTCA	SELEX Yin et al.(2017) TGIF1_eDBD_HT-SELEX	0.631	0.527
TGIF1 M09159_2.00	Homo sapiens	TGACAGS	SCTGTCA	Misc Kulakovskiy et al.(2013) TGIF1_HUMAN.H11MO.0.A	0.631	0.527
Tgif1 M09211_2.00	Mus musculus	TGACAGBNV	BNVCTGTCA	Misc Kulakovskiy et al.(2013) TGIF1_MOUSE.H11MO.0.A	0.631	0.527
TGIF1 M10740_2.00	Homo sapiens	WHNTGACARST	ASYTGTCANDW	Transfac Matys et al.(2006) V$TGIF_01	0.631	0.527
TGIF1 M05318_2.00	Homo sapiens	TGACAKVTGTCA	TGACABMTGTCA	SELEX Yin et al.(2017) TGIF1_eDBD_Methyl-HT-SELEX	0.631	0.527
achi M03860_2.00	Drosophila melanogaster	TGACAD	HTGTCA	SELEX Nitta et al.(2015) achi_1	0.622	0.509
achi M03861_2.00	Drosophila melanogaster	TGACAGMTGTCA	TGACAKCTGTCA	SELEX Nitta et al.(2015) achi_2	0.622	0.509
achi M03862_2.00	Drosophila melanogaster	TGACAGNNNNNNYGTCA	TGACRNNNNNNCTGTCA	SELEX Nitta et al.(2015) achi_3	0.622	0.509
vis M03859_2.00	Drosophila melanogaster	TGACAS	STGTCA	SELEX Nitta et al.(2015) vis_1	0.622	0.509
vis M06534_2.00	Drosophila melanogaster	TGACAB	BTGTCA	B1H Mathelier et al.(2014) MA0252.1	0.622	0.509
achi M06535_2.00	Drosophila melanogaster	TGACAG	CTGTCA	B1H Mathelier et al.(2014) MA0207.1	0.622	0.509
achi M06345_2.00	Drosophila melanogaster	TGTCADW	WHTGACA	B1H Zhu et al.(2011) Achi_Cell_FBgn0033749	0.622	0.509
achi M06346_2.00	Drosophila melanogaster	HTGACA	TGTCAD	B1H Zhu et al.(2011) Achi_SOLEXA_FBgn0033749	0.622	0.509
vis M06343_2.00	Drosophila melanogaster	TGTCA	TGACA	B1H Zhu et al.(2011) Vis_Cell_FBgn0033748	0.622	0.509
vis M06344_2.00	Drosophila melanogaster	TGTCAD	HTGACA	B1H Zhu et al.(2011) Vis_SOLEXA_FBgn0033748	0.622	0.509
TGIF2LX M03171_2.00	Homo sapiens	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) TGIF2LX_1	0.601	0.509
TGIF2LX M05191_2.00	Homo sapiens	TGACABVTGTCA	TGACABVTGTCA	SELEX Yin et al.(2017) TGIF2LX_eDBD_HT-SELEX	0.601	0.509
TGIF2LX M05193_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) TGIF2LX_FL_HT-SELEX	0.601	0.509
TGIF2LX M05192_2.00	Homo sapiens	TGACABVTGTCA	TGACABVTGTCA	SELEX Yin et al.(2017) TGIF2LX_eDBD_Methyl-HT-SELEX	0.601	0.509
TGIF2LX M05194_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) TGIF2LX_FL_Methyl-HT-SELEX	0.601	0.509
TGIF2LY M05313_2.00	Homo sapiens	TGACABVTGTCA	TGACABVTGTCA	SELEX Yin et al.(2017) TGIF2LY_eDBD_HT-SELEX	0.601	0.491
TGIF2LY M05314_2.00	Homo sapiens	YGACABVTGTCR	YGACABVTGTCR	SELEX Yin et al.(2017) TGIF2LY_eDBD_Methyl-HT-SELEX	0.601	0.491
For this family, TFs with SR scores > 0.599* will likely have a similar motif*

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
ENSTRUP00000007036	Homeodomain	206	263	KNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRI
ENSTRUP00000007037	Homeodomain	288	345	KNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRI
ENSTRUP00000007038	Homeodomain	289	346	KNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRI
ENSTRUP00000007039	Homeodomain	204	261	KNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRI

Links
Other Homeodomain family TFs
Other *Takifugu rubripes* TFs

799 Related TFs

Name	Species	Gene ID	Motif Evidence	SR Score	Action
A1O1_06448	Capronia coronata	A1O1_06448	N	0.000
A1O5_08664	Cladophialophora psammophila	A1O5_08664	N	0.000
A1O7_06479	Cladophialophora yegresii	A1O7_06479	N	0.000
A1O9_08053	Exophiala aquamarina	A1O9_08053	N	0.000
AB07644.1	Alternaria brassicicola	AB07644.1	N	0.000
ACLA_045490	Aspergillus clavatus	CADACLAG00004978	N	0.000
AFUA_4G06170	Aspergillus fumigatus	CADAFUAG00008511	N	0.000
ANIA_04324	Aspergillus nidulans	CADANIAG00006139	N	0.000
AUEXF2481DRAFT_168419	Aureobasidium subglaciale	AUEXF2481DRAFT_168419	N	0.000
BAUCODRAFT_118710	Baudoinia compniacensis	BAUCODRAFT_118710	N	0.000
BDDG_08069	Blastomyces dermatitidis	BDDG_08069	N	0.000
CADAFLAG00005113	Aspergillus flavus	CADAFLAG00005113	N	0.000
CADANGAG00003756	Aspergillus niger	CADANGAG00003756	N	0.000
CADAORAG00008051	Aspergillus oryzae	CADAORAG00008051	N	0.000
COCC4DRAFT_129366	Bipolaris maydis	COCC4DRAFT_129366	N	0.000
COCCADRAFT_28724	Bipolaris zeicola	COCCADRAFT_28724	N	0.000
COCMIDRAFT_26299	Bipolaris oryzae	COCMIDRAFT_26299	N	0.000
COCVIDRAFT_18953	Bipolaris victoriae	COCVIDRAFT_18953	N	0.000
DOTSEDRAFT_68488	Dothistroma septosporum	DOTSEDRAFT_68488	N	0.000
estExt_fgenesh1_kg.C_60062	Cochliobolus heterostrophus C5	estExt_fgenesh1_kg.C_60062	N	0.000
estExt_fgenesh1_pg.C_chr_11225	Mycosphaerella graminicola	estExt_fgenesh1_pg.C_chr_11225	N	0.000
EURHEDRAFT_516818	Aspergillus ruber	EURHEDRAFT_516818	N	0.000
fgenesh1_pg.00609_#_575	Aspergillus carbonarius	fgenesh1_pg.00609_#_575	N	0.000
fgenesh1_pg.C_scaffold_1000709	Mycosphaerella fijiensis	fgenesh1_pg.C_scaffold_1000709	N	0.000
G647_06053	Cladophialophora carrionii	G647_06053	N	0.000
GMDG_03916	Pseudogymnoascus destructans	GMDG_03916	N	0.000
HCBG_02231	Histoplasma capsulatum	HCBG_02231	N	0.000
HMPREF1120_03961	Exophiala dermatitidis	HMPREF1120_03961	N	0.000
LEMA_P055360.1	Leptosphaeria maculans	LEMA_P055360.1	N	0.000
M437DRAFT_51114	Aureobasidium melanogenum	M437DRAFT_51114	N	0.000
M438DRAFT_40073	Aureobasidium pullulans	M438DRAFT_40073	N	0.000
MBM_05804	Marssonina brunnea	MBM_05804	N	0.000
MPH_03233	Macrophomina phaseolina	MPH_03233	N	0.000
Mycgr3G107497	Zymoseptoria tritici	Mycgr3G107497	N	0.000
NFIA_109970	Neosartorya fischeri	CADNFIAG00009928	N	0.000
PAAG_04399	Paracoccidioides sp lutzii	PAAG_04399	N	0.000
PABG_04201	Paracoccidioides brasiliensis	PABG_04201	N	0.000
PMAA_027450	Penicillium marneffei	PMAA_027450	N	0.000
PMAA_027450	Talaromyces marneffei	PMAA_027450	N	0.000
PTRG_00938	Pyrenophora triticirepentis	PTRG_00938	N	0.000
PTT_04046	Pyrenophora teres	PTT_04046	N	0.000
PV04_06890	Capronia semiimmersa	PV04_06890	N	0.000
PV05_09061	Exophiala xenobiotica	PV05_09061	N	0.000
PV06_02579	Exophiala oligosperma	PV06_02579	N	0.000
PV07_03724	Cladophialophora immunda	PV07_03724	N	0.000
PV07_12548	Cladophialophora immunda	PV07_12548	N	0.000
PV08_11376	Exophiala spinifera	PV08_11376	N	0.000
PV09_02366	Verruconis gallopava	PV09_02366	N	0.000
PV10_08689	Exophiala mesophila	PV10_08689	N	0.000
PV11_06703	Exophiala sideris	PV11_06703	N	0.000
PVAR5_4132	Byssochlamys spectabilis	PVAR5_4132	N	0.000
SEPMUDRAFT_145925	Sphaerulina musiva	SEPMUDRAFT_145925	N	0.000
SETTUDRAFT_98045	Setosphaeria turcica	SETTUDRAFT_98045	N	0.000
TSTA_071310	Talaromyces stipitatus	TSTA_071310	N	0.000
UCRNP2_8887	Neofusicoccum parvum	UCRNP2_8887	N	0.000
W97_00412	Coniosporium apollinis	W97_00412	N	0.000
Z517_00960	Fonsecaea pedrosoi	Z517_00960	N	0.000
Z518_02769	Rhinocladiella mackenziei	Z518_02769	N	0.000
Z519_03993	Cladophialophora bantiana	Z519_03993	N	0.000

pknox2 (Takifugu rubripes) Homeodomain

TF Information

Directly determined binding motifs

Motifs from related TFs

DNA Binding Domains

Links

799 Related TFs

pknox2 **(Takifugu rubripes)
Homeodomain**