CIS-BP Database: Catalog of Inferred Sequence Binding Preferences

TF Information

Tal_R012809 *(Tyto alba)* Homeodomain
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source
PF00046 (Homeobox)	IPR001356	Tal_R012809	T226920_2.00	GigaDB (2015-Oct-22)
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
Dmbx1 M00441_2.00	Mus musculus	NTAATCYNN	NNRGATTAN	PBM Berger et al.(2008) Dmbx1_2277	0.867	1.000
DMBX1 M03236_2.00	Homo sapiens	NHTAATCCBN	NVGGATTADN	SELEX Jolma et al.(2013) DMBX1_1	0.867	1.000
DMBX1 M05383_2.00	Homo sapiens	NTAATCSN	NSGATTAN	SELEX Yin et al.(2017) DMBX1_eDBD_HT-SELEX	0.867	1.000
DMBX1 M05384_2.00	Homo sapiens	HTAATCCN	NGGATTAD	SELEX Yin et al.(2017) DMBX1_eDBD_Methyl-HT-SELEX	0.867	1.000
ceh-53 M00679_2.00	Caenorhabditis elegans	HTAATCYN	NRGATTAD	PBM Narasimhan et al.(2015) pTH10699	0.817	0.649
CRX M00274_2.00	Homo sapiens	NMTAATCCSN	NSGGATTAKN	PBM Barrera et al.(2016) CRX_REF	0.775	0.667
Crx M00489_2.00	Mus musculus	NWAAKMBN	NVKMTTWN	PBM Berger et al.(2008) Crx_3485	0.775	0.667
CRX M04949_2.00	Homo sapiens	NTAATCCN	NGGATTAN	SELEX Yin et al.(2017) CRX_FL_HT-SELEX	0.775	0.667
Crx M08139_2.00	Mus musculus	YTAATCCYCYY	RRGRGGATTAR	ChIP-seq Mathelier et al.(2014) MA0467.1	0.775	0.667
CRX M09132_2.00	Homo sapiens	BYTAATCCBHYYN	NRRDVGGATTARV	Misc Kulakovskiy et al.(2013) CRX_HUMAN.H11MO.0.B	0.775	0.667
Crx M09208_2.00	Mus musculus	BYTAATCCBHYYN	NRRDVGGATTARV	Misc Kulakovskiy et al.(2013) CRX_MOUSE.H11MO.0.A	0.775	0.667
Crx M09577_2.00	Mus musculus	NYTAATCC	GGATTARN	Misc Heinz et al.(2010) Retina-Crx_GSE20012	0.775	0.667
CRX M10647_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$CRX_Q4_01	0.775	0.667
CRX M10648_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$CRX_Q4_02	0.775	0.667
CRX M04950_2.00	Homo sapiens	HTAATCCN	NGGATTAD	SELEX Yin et al.(2017) CRX_FL_Methyl-HT-SELEX	0.775	0.667
Gsc M02120_2.00	Drosophila melanogaster	NTAATCYN	NRGATTAN	PBM Weirauch et al.(2014) pTH5511	0.772	0.702
Gsc M03817_2.00	Drosophila melanogaster	TAATCCB	VGGATTA	SELEX Nitta et al.(2015) Gsc_1	0.772	0.702
Gsc M03818_2.00	Drosophila melanogaster	TAATCGGATTA	TAATCCGATTA	SELEX Nitta et al.(2015) Gsc_2	0.772	0.702
Gsc M03819_2.00	Drosophila melanogaster	TAATCYNHTAATCBN	NVGATTADNRGATTA	SELEX Nitta et al.(2015) Gsc_3	0.772	0.702
Gsc M03820_2.00	Drosophila melanogaster	TAATCGGATTA	TAATCCGATTA	SELEX Nitta et al.(2015) Gsc_4	0.772	0.702
Gsc M03821_2.00	Drosophila melanogaster	TAATCYNWTWATCYB	VRGATWAWNRGATTA	SELEX Nitta et al.(2015) Gsc_5	0.772	0.702
Gsc M05873_2.00	Drosophila melanogaster	TAATCSNHTWA	TWADNSGATTA	SMiLE-seq Isakova et al.(2017) Gsc	0.772	0.702
Gsc M06509_2.00	Drosophila melanogaster	TAATCY	RGATTA	B1H Mathelier et al.(2014) MA0190.1	0.772	0.702
Gsc M06297_2.00	Drosophila melanogaster	VNTAATCY	RGATTANB	B1H Zhu et al.(2011) Gsc_Cell_FBgn0010323	0.772	0.702
Gsc M06298_2.00	Drosophila melanogaster	NTAATCY	RGATTAN	B1H Zhu et al.(2011) Gsc_SOLEXA_FBgn0010323	0.772	0.702
ceh-37 M00674_2.00	Caenorhabditis elegans	HTAATCYN	NRGATTAD	PBM Narasimhan et al.(2015) pTH10716	0.769	0.596
CRX M00275_2.00	Homo sapiens	NMTAATCCSN	NSGGATTAKN	PBM Barrera et al.(2016) CRX_V66I	0.765	0.649
CRX M00273_2.00	Homo sapiens	NNYTAATCCVN	NBGGATTARNN	PBM Barrera et al.(2016) CRX_R90W	0.765	0.649
Otx1 M00396_2.00	Mus musculus	NTAAKCYN	NRGMTTAN	PBM Berger et al.(2008) Otx1_2325	0.764	0.649
Otx2 M00418_2.00	Mus musculus	NTAAKMBN	NVKMTTAN	PBM Berger et al.(2008) Otx2_3441	0.764	0.649
OTX1 M03116_2.00	Homo sapiens	NNTAAKCGGATTANN	NNTAATCCGMTTANN	SELEX Jolma et al.(2013) OTX1_1	0.764	0.649
OTX1 M03117_2.00	Homo sapiens	NTAATCSB	VSGATTAN	SELEX Jolma et al.(2013) OTX1_2	0.764	0.649
OTX2 M03197_2.00	Homo sapiens	NHTAAKCGGATTANN	NNTAATCCGMTTADN	SELEX Jolma et al.(2013) OTX2_1	0.764	0.649
OTX2 M03198_2.00	Homo sapiens	HTAATCCB	VGGATTAD	SELEX Jolma et al.(2013) OTX2_2	0.764	0.649
Otx1 M03249_2.00	Mus musculus	NNTAAKCGGATTANN	NNTAATCCGMTTANN	SELEX Jolma et al.(2013) Otx1_1	0.764	0.649
Otx1 M03250_2.00	Mus musculus	NTAATCCN	NGGATTAN	SELEX Jolma et al.(2013) Otx1_2	0.764	0.649
oc M03808_2.00	Drosophila melanogaster	HTAATCCB	VGGATTAD	SELEX Nitta et al.(2015) oc_1	0.764	0.649
OTX1 M05022_2.00	Homo sapiens	NTAATCCN	NGGATTAN	SELEX Yin et al.(2017) OTX1_eDBD_HT-SELEX	0.764	0.649
OTX1 M05024_2.00	Homo sapiens	NTAATCCNNN	NNNGGATTAN	SELEX Yin et al.(2017) OTX1_FL_HT-SELEX	0.764	0.649
OTX2 M05251_2.00	Homo sapiens	NTAATCCN	NGGATTAN	SELEX Yin et al.(2017) OTX2_FL_HT-SELEX	0.764	0.649
oc M06502_2.00	Drosophila melanogaster	TAATCC	GGATTA	B1H Mathelier et al.(2014) MA0234.1	0.764	0.649
oc M06282_2.00	Drosophila melanogaster	WTAATCC	GGATTAW	B1H Zhu et al.(2011) Oc_Cell_FBgn0004102	0.764	0.649
oc M06283_2.00	Drosophila melanogaster	NTAATCCB	VGGATTAN	B1H Zhu et al.(2011) Oc_SOLEXA_FBgn0004102	0.764	0.649
OTX2 M09153_2.00	Homo sapiens	BYTAATCCYYN	NRRGGATTARV	Misc Kulakovskiy et al.(2013) OTX2_HUMAN.H11MO.0.A	0.764	0.649
Otx2 M09183_2.00	Mus musculus	HTAATCCYNYNN	NNRNRGGATTAD	Misc Kulakovskiy et al.(2013) OTX2_MOUSE.H11MO.0.A	0.764	0.649
Otx2 M09569_2.00	Mus musculus	NHTAATCCHB	VDGGATTADN	Misc Heinz et al.(2010) EpiLC-Otx2_GSE56098	0.764	0.649
oc M09681_2.00	Drosophila melanogaster	HTAATCCN	NGGATTAD	Misc Kulakovskiy et al.(2009) oc	0.764	0.649
OTX1 M10673_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$OTX1_Q5	0.764	0.649
OTX2 M10727_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$OTX2_Q3_01	0.764	0.649
OTX2 M10728_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$OTX2_Q3	0.764	0.649
OTX1 M05023_2.00	Homo sapiens	NTAATCCN	NGGATTAN	SELEX Yin et al.(2017) OTX1_eDBD_Methyl-HT-SELEX	0.764	0.649
OTX1 M05025_2.00	Homo sapiens	HTAATCCNHN	NDNGGATTAD	SELEX Yin et al.(2017) OTX1_FL_Methyl-HT-SELEX	0.764	0.649
OTX2 M05252_2.00	Homo sapiens	NTAATCCN	NGGATTAN	SELEX Yin et al.(2017) OTX2_FL_Methyl-HT-SELEX	0.764	0.649
PITX2 M00311_2.00	Homo sapiens	TTAATCCY	RGGATTAA	PBM Barrera et al.(2016) PITX2_R108H	0.760	0.684
NEMVEDRAFT_v1g113057 M02144_2.00	Nematostella vectensis	NYTAATCCBN	NVGGATTARN	PBM Weirauch et al.(2014) pTH6135	0.755	0.579
PITX2 M00313_2.00	Homo sapiens	NWAAKHYN	NRDMTTWN	PBM Barrera et al.(2016) PITX2_REF	0.755	0.667
Pitx1 M00415_2.00	Mus musculus	NTAATCYNN	NNRGATTAN	PBM Berger et al.(2008) Pitx1_2312	0.755	0.667
Pitx3 M00428_2.00	Mus musculus	NTAAKCYN	NRGMTTAN	PBM Berger et al.(2008) Pitx3_3497	0.755	0.667
Pitx2 M00440_2.00	Mus musculus	NTAATCCN	NGGATTAN	PBM Berger et al.(2008) Pitx2_2274	0.755	0.667
PITX1 M03082_2.00	Homo sapiens	NHTAATCCN	NGGATTADN	SELEX Jolma et al.(2013) PITX1_1	0.755	0.667
PITX1 M03083_2.00	Homo sapiens	NHTAATCCN	NGGATTADN	SELEX Jolma et al.(2013) PITX1_2	0.755	0.667
PITX1 M03084_2.00	Homo sapiens	HTAATCCN	NGGATTAD	SELEX Jolma et al.(2013) PITX1_3	0.755	0.667
PITX3 M03111_2.00	Homo sapiens	NHTAATCCN	NGGATTADN	SELEX Jolma et al.(2013) PITX3_1	0.755	0.667
PITX1 M04928_2.00	Homo sapiens	NTAATCCN	NGGATTAN	SELEX Yin et al.(2017) PITX1_eDBD_HT-SELEX	0.755	0.667
PITX1 M04930_2.00	Homo sapiens	NTAATCCN	NGGATTAN	SELEX Yin et al.(2017) PITX1_FL_HT-SELEX	0.755	0.667
PITX2 M05229_2.00	Homo sapiens	NTAAKCCN	NGGMTTAN	SELEX Yin et al.(2017) PITX2_eDBD_HT-SELEX	0.755	0.667
PITX2 M05231_2.00	Homo sapiens	NTAATCCN	NGGATTAN	SELEX Yin et al.(2017) PITX2_FL_HT-SELEX	0.755	0.667
PITX3 M04997_2.00	Homo sapiens	NTAATCCN	NGGATTAN	SELEX Yin et al.(2017) PITX3_eDBD_HT-SELEX	0.755	0.667
Pitx1 M09182_2.00	Mus musculus	NYWAAKCCYH	DRGGMTTWRN	Misc Kulakovskiy et al.(2013) PITX1_MOUSE.H11MO.0.C	0.755	0.667
PITX1 M10640_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PITX1_Q4	0.755	0.667
PITX1 M10641_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PITX1_Q6	0.755	0.667
PITX2 M10720_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PITX2_Q2	0.755	0.667
PITX2 M10721_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PITX2_Q4	0.755	0.667
PITX2 M10722_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PITX2_Q6	0.755	0.667
PITX3 M10660_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PITX3_Q2	0.755	0.667
PITX3 M10661_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PITX3_Q3_01	0.755	0.667
PITX3 M10662_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PITX3_Q3	0.755	0.667
PITX2 M00312_2.00	Homo sapiens	NNNTATWAATTNN	NNAATTWATANNN	PBM Barrera et al.(2016) PITX2_R130W	0.755	0.667
PITX2 M00314_2.00	Homo sapiens	NTAATMYN	NRKATTAN	PBM Barrera et al.(2016) PITX2_T114P	0.755	0.667
PITX1 M04929_2.00	Homo sapiens	NTAAKCCN	NGGMTTAN	SELEX Yin et al.(2017) PITX1_eDBD_Methyl-HT-SELEX	0.755	0.667
PITX1 M04931_2.00	Homo sapiens	HTAATCCN	NGGATTAD	SELEX Yin et al.(2017) PITX1_FL_Methyl-HT-SELEX	0.755	0.667
PITX2 M05230_2.00	Homo sapiens	HTAATCCN	NGGATTAD	SELEX Yin et al.(2017) PITX2_eDBD_Methyl-HT-SELEX	0.755	0.667
PITX2 M05232_2.00	Homo sapiens	YTAATCCY	RGGATTAR	SELEX Yin et al.(2017) PITX2_FL_Methyl-HT-SELEX	0.755	0.667
PITX3 M04998_2.00	Homo sapiens	NTAATCCN	NGGATTAN	SELEX Yin et al.(2017) PITX3_eDBD_Methyl-HT-SELEX	0.755	0.667
PITX2 M00310_2.00	Homo sapiens	HTAATCYN	NRGATTAD	PBM Barrera et al.(2016) PITX2_L100Q	0.755	0.649
Ptx1 M02123_2.00	Drosophila melanogaster	NTAATCYNN	NNRGATTAN	PBM Weirauch et al.(2014) pTH5644	0.755	0.667
Ptx1 M00562_2.00	Drosophila melanogaster	NYTAATCCBN	NVGGATTARN	PBM Busser et al.(2012a) Ptx1	0.755	0.667
Ptx1 M03842_2.00	Drosophila melanogaster	NTAATCCN	NGGATTAN	SELEX Nitta et al.(2015) Ptx1_1	0.755	0.667
Ptx1 M03843_2.00	Drosophila melanogaster	NTAATCCN	NGGATTAN	SELEX Nitta et al.(2015) Ptx1_2	0.755	0.667
Ptx1 M03844_2.00	Drosophila melanogaster	NCGHTAATCCN	NGGATTADCGN	SELEX Nitta et al.(2015) Ptx1_3	0.755	0.667
Ptx1 M06521_2.00	Drosophila melanogaster	YTAATCC	GGATTAR	B1H Mathelier et al.(2014) MA0201.1	0.755	0.667
Ptx1 M06319_2.00	Drosophila melanogaster	YTAATCC	GGATTAR	B1H Zhu et al.(2011) Ptx1_Cell_FBgn0020912	0.755	0.667
Ptx1 M06320_2.00	Drosophila melanogaster	NYTAATCC	GGATTARN	B1H Zhu et al.(2011) Ptx1_SOLEXA_FBgn0020912	0.755	0.667
CRX M00270_2.00	Homo sapiens	NWDAKNN	NNMTHWN	PBM Barrera et al.(2016) CRX_E80A	0.755	0.649
ceh-36 M00673_2.00	Caenorhabditis elegans	NWAATCYN	NRGATTWN	PBM Narasimhan et al.(2015) pTH10730	0.753	0.632
HBX4_ECHGR M02195_2.00	Echinococcus granulosus	NHTAATCYNN	NNRGATTADN	PBM Weirauch et al.(2014) pTH6301	0.753	0.561
CBG01820 M01241_2.00	Caenorhabditis briggsae	NTAATCCN	NGGATTAN	PBM Lambert et al.(2019) pTH11454	0.747	0.561
CRX M00271_2.00	Homo sapiens	NHDAKNN	NNMTHDN	PBM Barrera et al.(2016) CRX_R41Q	0.742	0.649
CRX M00272_2.00	Homo sapiens	NNHNATNN	NNATNDNN	PBM Barrera et al.(2016) CRX_R41W	0.742	0.649
Gsc M00411_2.00	Mus musculus	NNTAATYBN	NVRATTANN	PBM Berger et al.(2008) Gsc_2327	0.741	0.632
GSC M03146_2.00	Homo sapiens	NHTAATCCNH	DNGGATTADN	SELEX Jolma et al.(2013) GSC_1	0.741	0.632
GSC M05134_2.00	Homo sapiens	NTAATCCB	VGGATTAN	SELEX Yin et al.(2017) GSC_eDBD_HT-SELEX	0.741	0.632
GSC M05136_2.00	Homo sapiens	HTAATCCN	NGGATTAD	SELEX Yin et al.(2017) GSC_FL_HT-SELEX	0.741	0.632
gsc M09584_2.00	Xenopus tropicalis	NTAATCYN	NRGATTAN	Misc Heinz et al.(2010) FrogEmbryos-GSC_DRA000576	0.741	0.632
GSC M05135_2.00	Homo sapiens	HTAATCCB	VGGATTAD	SELEX Yin et al.(2017) GSC_eDBD_Methyl-HT-SELEX	0.741	0.632
GSC M05137_2.00	Homo sapiens	HTAATCCN	NGGATTAD	SELEX Yin et al.(2017) GSC_FL_Methyl-HT-SELEX	0.741	0.632
GSC2 M03080_2.00	Homo sapiens	NHTAATCCBH	DVGGATTADN	SELEX Jolma et al.(2013) GSC2_1	0.739	0.596
GSC2 M04920_2.00	Homo sapiens	NTAATNNN	NNNATTAN	SELEX Yin et al.(2017) GSC2_eDBD_HT-SELEX	0.739	0.596
GSC2 M04921_2.00	Homo sapiens	NTAATCYN	NRGATTAN	SELEX Yin et al.(2017) GSC2_eDBD_Methyl-HT-SELEX	0.739	0.596
DPRX M03237_2.00	Homo sapiens	NHTAATCYNN	NNRGATTADN	SELEX Jolma et al.(2013) DPRX_1	0.691	0.404
DPRX M03238_2.00	Homo sapiens	NRGMTAATCYN	NRGATTAKCYN	SELEX Jolma et al.(2013) DPRX_2	0.691	0.404
DPRX M05388_2.00	Homo sapiens	VGMTAATCYN	NRGATTAKCB	SELEX Yin et al.(2017) DPRX_eDBD_HT-SELEX	0.691	0.404
DPRX M05389_2.00	Homo sapiens	AGATMATCYN	NRGATKATCT	SELEX Yin et al.(2017) DPRX_eDBD_Methyl-HT-SELEX	0.691	0.404
Obox6 M00490_2.00	Mus musculus	NTAATCYNN	NNRGATTAN	PBM Berger et al.(2008) Obox6_3440	0.620	0.386
AGAP006642 M02035_2.00	Anopheles gambiae	NHTAATCY	RGATTADN	PBM Weirauch et al.(2014) pTH6201	0.615	0.316
dve M02122_2.00	Drosophila melanogaster	NTAATCCV	BGGATTAN	PBM Weirauch et al.(2014) pTH6218	0.615	0.316
dharma M02080_2.00	Danio rerio	NNRAKCY	RGMTYNN	PBM Weirauch et al.(2014) pTH6530	0.613	0.509
For this family, TFs with SR scores > 0.599* will likely have a similar motif*

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
Tal_R012809	Homeodomain	67	123	RRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRK

Links
Other Homeodomain family TFs
Other *Tyto alba* TFs

1139 Related TFs

Name	Species	Gene ID	Motif Evidence	SR Score	Action
AAEL011825	Aedes aegypti	AAEL011825	I
ACEP12067	Atta cephalotes	ACEP12067	I
CLEC009101	Cimex lectularius	CLEC009101	I
DILT_0000966101	Diphyllobothrium latum	DILT_0000966101	I
ECPE_0000485601	Echinostoma caproni	ECPE_0000485601	I
EmuJ_000434100	Echinococcus multilocularis	EmuJ_000434100	I
ENSLOCG00000011345	Lepisosteus oculatus	ENSLOCG00000011345	N
ENSOANG00000009611	Ornithorhynchus anatinus	ENSOANG00000009611	N
GA20013	Drosophila pseudoobscura	FBgn0080009	I
GB54493	Apis mellifera	GB54493	I
GE26316	Drosophila yakuba	FBgn0243346	I
GF16518	Drosophila ananassae	FBgn0093539	I
GG19993	Drosophila erecta	FBgn0112192	I
GH18248	Drosophila grimshawi	FBgn0125716	I
GI23647	Drosophila mojavensis	FBgn0146373	I
GJ23490	Drosophila virilis	FBgn0210588	I
GK13504	Drosophila willistoni	FBgn0215512	I
GL22243	Drosophila persimilis	FBgn0159835	I
HDID_0000348401	Hymenolepis diminuta	HDID_0000348401	N
HMEL007610	Heliconius melpomene	HMEL007610	I
HmN_000855200	Hymenolepis microstoma	HmN_000855200	I
HNAJ_0001000501	Hymenolepis nana	HNAJ_0001000501	I
Hsal_00743--XP_394737.3_APIME	Harpegnathos saltator	Hsal_00743--XP_394737.3_APIME	I
ISCW019892	Ixodes scapularis	ISCW019892	I
L798_12532	Zootermopsis nevadensis	L798_12532	I
LCUP007701	Lucilia cuprina	LCUP007701	I
LDEC011571	Leptinotarsa decemlineata	LDEC011571	I
MCINX002971	Melitaea cinxia	MCINX002971	I
MDOA012868	Musca domestica	MDOA012868	I
NV14135	Nasonia vitripennis	NV14135	I
Ogr18615	Ophisaurus gracilis	Ogr18615	N
PHUM298050	Pediculus humanus	PHUM298050	I
RPRC012076	Rhodnius prolixus	RPRC012076	I
SMAR001354	Strigamia maritima	SMAR001354	I
ss	Drosophila melanogaster	FBgn0003513	D
TC011105	Tribolium castaneum	TC011105	I
tetur03g01600	Tetranychus urticae	tetur03g01600	N
TsM_000000500	Taenia solium	TsM_000000500	I
TTAC_0000255601	Hydatigera taeniaeformis	TTAC_0000255601	I

Tal_R012809 (Tyto alba) Homeodomain

TF Information

Directly determined binding motifs

Motifs from related TFs

DNA Binding Domains

Links

1139 Related TFs

Tal_R012809 **(Tyto alba)
Homeodomain**