IRF1 (Homo sapiens)
IRF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00605 (IRF) IPR001346 ENSG00000125347 T244078_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
IRF1
M08142_2.00		 Homo sapiens
RWANNGAAASYGAAASYRNNN
NNNYRSTTTCRSTTTCNNTWY		 ChIP-seq
Mathelier et al.(2014)
MA0050.2		 (Direct) (Direct)
IRF1
M09233_2.00		 Homo sapiens
NRAANNGAAASWGAAASHRN
NYDSTTTCWSTTTCNNTTYN		 Misc
Kulakovskiy et al.(2013)
IRF1_HUMAN.H11MO.0.A		 (Direct) (Direct)
IRF1
M09594_2.00		 Homo sapiens
GAAASTGAAASY
RSTTTCASTTTC		 Misc
Heinz et al.(2010)
PBMC-IRF1_GSE43036		 (Direct) (Direct)
IRF1
M10879_2.00		 Homo sapiens
SAAAASYGAAASY
RSTTTCRSTTTTS		 Transfac
Matys et al.(2006)
V$IRF1_01		 (Direct) (Direct)
IRF1
M10880_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF1_03		 (Direct) (Direct)
IRF1
M10881_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF1_Q5		 (Direct) (Direct)
IRF1
M10882_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF1_Q6		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Irf1
M09242_2.00 		Mus musculus
VRAANNGAAASYGAAASYVN
NBRSTTTCRSTTTCNNTTYB		 Misc
Kulakovskiy et al.(2013)
IRF1_MOUSE.H11MO.0.A 		1.000 1.000
Irf2
M00805_2.00 		Mus musculus
NDWNHGAAAV
BTTTCDNWHN		 PBM
Weirauch et al.(2013)
pTH2835 		0.771 0.771
IRF2
M05545_2.00 		Homo sapiens
NGAAAVYGAAAS
STTTCRBTTTCN		 SELEX
Yin et al.(2017)
IRF2_FL_HT-SELEX 		0.771 0.771
IRF2
M02691_2.00 		Homo sapiens
SGAAAGYGAAASYNWWHH
DDWWNRSTTTCRCTTTCS		 SELEX
Mathelier et al.(2014)
MA0051.1 		0.771 0.771
IRF2
M09237_2.00 		Homo sapiens
NRAANNGAAASYGAAASYRV
BYRSTTTCRSTTTCNNTTYN		 Misc
Kulakovskiy et al.(2013)
IRF2_HUMAN.H11MO.0.A 		0.771 0.771
Irf2
M09245_2.00 		Mus musculus
NRAANNGAAASYGAAASYRV
BYRSTTTCRSTTTCNNTTYN		 Misc
Kulakovskiy et al.(2013)
IRF2_MOUSE.H11MO.0.B 		0.771 0.771
IRF2
M09596_2.00 		Homo sapiens
NRAAVNRRAASB
VSTTYYNBTTYN		 Misc
Heinz et al.(2010)
Erythroblas-IRF2_GSE36985 		0.771 0.771
IRF2
M10892_2.00 		Homo sapiens
GAAAAGYGAAASY
RSTTTCRCTTTTC		 Transfac
Matys et al.(2006)
V$IRF2_01 		0.771 0.771
IRF2
M10893_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF2_Q6 		0.771 0.771
IRF2
M05546_2.00 		Homo sapiens
NGAAASYGAAAS
STTTCRSTTTCN		 SELEX
Yin et al.(2017)
IRF2_FL_Methyl-HT-SELEX 		0.771 0.771
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000245414 IRF 7 112
ENSP00000384406 IRF 7 112
ENSP00000392455 IRF 7 45
ENSP00000396318 IRF 7 112
ENSP00000405655 IRF 7 112
ENSP00000473661 IRF 7 112
ENSP00000480887 IRF 7 112

Links

Other IRF family TFs
Other Homo sapiens TFs

128 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Aan_R004209 Calypte anna Aan_R004209 I 0.781
Aan_R011063 Calypte anna Aan_R011063 I 0.924
Afo_R012154 Aptenodytes forsteri Afo_R012154 I 0.924
Afo_R013359 Aptenodytes forsteri Afo_R013359 I 0.781
Alligator_sinensis_CCG004039.1 Alligator sinensis Alligator_sinensis_CCG004039.1 I 0.914
Brh_R001640 Buceros rhinoceros Brh_R001640 I 0.781
Brh_R004433 Buceros rhinoceros Brh_R004433 I 0.905
Cmyd_10017697 Chelonia mydas Cmyd_10017697 I 0.771
ENSAMEG00000008380 Ailuropoda melanoleuca ENSAMEG00000008380 I 0.771
ENSAMEG00000017694 Ailuropoda melanoleuca ENSAMEG00000017694 I 1.000
ENSAMXG00000005897 Astyanax mexicanus ENSAMXG00000005897 I 0.752
ENSAMXG00000010595 Astyanax mexicanus ENSAMXG00000010595 I 0.743
ENSAPLG00000009708 Anas platyrhynchos ENSAPLG00000009708 I 0.924
ENSAPLG00000015442 Anas platyrhynchos ENSAPLG00000015442 I 0.790
ENSBTAP00000013193-D1 Bos grunniens ENSBTAP00000013193-D1 I 0.762
ENSCSAG00000003010 Chlorocebus sabaeus ENSCSAG00000003010 I 0.771
ENSCSAG00000013810 Chlorocebus sabaeus ENSCSAG00000013810 I 0.981
ENSDORG00000003799 Dipodomys ordii ENSDORG00000003799 I 0.990
ENSFALG00000011727 Ficedula albicollis ENSFALG00000011727 I 0.781
ENSFALG00000013442 Ficedula albicollis ENSFALG00000013442 I 0.914
ENSGMOG00000016692 Gadus morhua ENSGMOG00000016692 I 0.733
ENSLACG00000001546 Latimeria chalumnae ENSLACG00000001546 I 0.857
ENSLACG00000004013 Latimeria chalumnae ENSLACG00000004013 I 0.762
ENSLOCG00000010331 Lepisosteus oculatus ENSLOCG00000010331 I 0.838
ENSLOCG00000013738 Lepisosteus oculatus ENSLOCG00000013738 I 0.752
ENSMEUG00000003128 Macropus eugenii ENSMEUG00000003128 I 0.708
ENSMEUG00000011152 Macropus eugenii ENSMEUG00000011152 I 0.976
ENSMPUG00000010522 Mustela putorius furo ENSMPUG00000010522 I 1.000
ENSMPUG00000011075 Mustela putorius furo ENSMPUG00000011075 I 0.771
ENSNLEG00000010848 Nomascus leucogenys ENSNLEG00000010848 I 0.771
ENSNLEG00000012720 Nomascus leucogenys ENSNLEG00000012720 I 1.000
ENSOARG00000007443 Ovis aries ENSOARG00000007443 I 0.762
ENSOARG00000015078 Ovis aries ENSOARG00000015078 I 1.000
ENSONIG00000015919 Oreochromis niloticus ENSONIG00000015919 I 0.743
ENSONIG00000017217 Oreochromis niloticus ENSONIG00000017217 I 0.714
ENSP00000377218 Macaca fascicularis ENSP00000377218 I 0.771
ENSP00000384406 Macaca fascicularis ENSP00000384406 I 1.000
ENSP00000384406-D1 Bos grunniens ENSP00000384406-D1 I 1.000
ENSPANG00000014875 Papio anubis ENSPANG00000014875 I 1.000
ENSPFOG00000006505 Poecilia formosa ENSPFOG00000006505 I 0.762
ENSPPYG00000015762 Pongo abelii ENSPPYG00000015762 I 1.000
ENSPSIG00000010399 Pelodiscus sinensis ENSPSIG00000010399 I 0.895
ENSPSIG00000016830 Pelodiscus sinensis ENSPSIG00000016830 I 0.762
ENSSHAG00000002124 Sarcophilus harrisii ENSSHAG00000002124 I 0.762
ENSSHAG00000009209 Sarcophilus harrisii ENSSHAG00000009209 I 0.962
ENSSTOG00000009857 Ictidomys tridecemlineatus ENSSTOG00000009857 I 1.000
ENSTSYG00000001107 Tarsius syrichta ENSTSYG00000001107 I 1.000
ENSTSYG00000003453 Tarsius syrichta ENSTSYG00000003453 I 0.800
ENSXMAG00000004071 Xiphophorus maculatus ENSXMAG00000004071 I 0.762
ENSXMAG00000011087 Xiphophorus maculatus ENSXMAG00000011087 I 0.705
Gfo_R010481 Geospiza fortis Gfo_R010481 I 0.781
Gfo_R013143 Geospiza fortis Gfo_R013143 I 0.914
IRF1 Anolis carolinensis ENSACAG00000012699 I 0.819
IRF1 Bos taurus ENSBTAG00000031231 I 1.000
IRF1 Canis familiaris ENSCAFG00000000851 I 1.000
IRF1 Callithrix jacchus ENSCJAG00000013013 I 1.000
IRF1 Cavia porcellus ENSCPOG00000004848 I 0.990
IRF1 Dasypus novemcinctus ENSDNOG00000035479 I 1.000
IRF1 Equus caballus ENSECAG00000017794 I 1.000
IRF1 Erinaceus europaeus ENSEEUG00000013362 I 1.000
IRF1 Felis catus ENSFCAG00000013318 I 1.000
IRF1 Gallus gallus ENSGALG00000006785 I 0.933
IRF1 Gorilla gorilla ENSGGOG00000013927 I 1.000
IRF1 Loxodonta africana ENSLAFG00000007502 I 0.981
IRF1 Meleagris gallopavo ENSMGAG00000008932 I 0.933
IRF1 Microcebus murinus ENSMICG00000008190 I 1.000
IRF1 Myotis lucifugus ENSMLUG00000016545 I 0.981
IRF1 Macaca mulatta ENSMMUG00000008100 I 1.000
IRF1 Monodelphis domestica ENSMODG00000013963 I 0.962
Irf1 Mus musculus ENSMUSG00000018899 D 1.000
IRF1 Ornithorhynchus anatinus ENSOANG00000010695 I 0.962
IRF1 Oryctolagus cuniculus ENSOCUG00000004165 I 1.000
IRF1 Otolemur garnettii ENSOGAG00000015489 I 0.990
IRF1 Procavia capensis ENSPCAG00000017088 I 0.981
IRF1 Pan troglodytes ENSPTRG00000017216 I 1.000
IRF1 Pteropus vampyrus ENSPVAG00000000430 I 1.000
Irf1 Rattus norvegicus ENSRNOG00000008144 I 0.990
IRF1 Sorex araneus ENSSARG00000006226 I 1.000
IRF1 Sus scrofa ENSSSCG00000014277 I 1.000
IRF1 Taeniopygia guttata ENSTGUG00000001375 I 0.914
IRF1 Tursiops truncatus ENSTTRG00000002597 I 0.990
irf1 Xenopus tropicalis XB-GENE-942994 I 0.867
irf1.L Xenopus laevis XB-GENE-6255163 I 0.848
irf1.S Xenopus laevis XB-GENE-17345840 I 0.857
IRF2 Bos taurus ENSBTAG00000010002 I 0.762
IRF2 Canis familiaris ENSCAFG00000007761 I 0.771
IRF2 Choloepus hoffmanni ENSCHOG00000012067 I 0.738
IRF2 Callithrix jacchus ENSCJAG00000005731 I 0.771
IRF2 Cavia porcellus ENSCPOG00000013097 I 0.781
irf2 Danio rerio ENSDARG00000040465 I 0.771
IRF2 Equus caballus ENSECAG00000007508 I 0.771
IRF2 Felis catus ENSFCAG00000030144 I 0.771
IRF2 Homo sapiens ENSG00000168310 D 0.771
irf2 Gasterosteus aculeatus ENSGACG00000018763 I 0.752
IRF2 Gallus gallus ENSGALG00000010642 I 0.790
IRF2 Gorilla gorilla ENSGGOG00000016559 I 0.771
IRF2 Loxodonta africana ENSLAFG00000000088 I 0.771
IRF2 Meleagris gallopavo ENSMGAG00000006359 I 0.781
IRF2 Microcebus murinus ENSMICG00000015506 I 0.771
IRF2 Myotis lucifugus ENSMLUG00000014246 I 0.771
IRF2 Macaca mulatta ENSMMUG00000015087 I 0.771
IRF2 Monodelphis domestica ENSMODG00000004393 I 0.771
Irf2 Mus musculus ENSMUSG00000031627 D 0.771
IRF2 Oryctolagus cuniculus ENSOCUG00000009229 I 0.771
IRF2 Otolemur garnettii ENSOGAG00000010966 I 0.771
IRF2 Ochotona princeps ENSOPRG00000005398 I 0.762
irf2 Oryzias latipes ENSORLG00000008574 I 0.752
IRF2 Pan troglodytes ENSPTRG00000016639 I 0.762
IRF2 Pteropus vampyrus ENSPVAG00000007078 I 0.771
Irf2 Rattus norvegicus ENSRNOG00000009824 I 0.771
IRF2 Sus scrofa ENSSSCG00000015782 I 0.771
IRF2 Taeniopygia guttata ENSTGUG00000006662 I 0.781
irf2 Takifugu rubripes ENSTRUG00000001842 I 0.762
IRF2 Tursiops truncatus ENSTTRG00000009391 I 0.771
IRF2 Vicugna pacos ENSVPAG00000011297 I 0.752
irf2 Xenopus tropicalis XB-GENE-942910 I 0.752
irf2.L Xenopus laevis XB-GENE-942916 I 0.733
irf2.S Xenopus laevis XB-GENE-17339545 I 0.752
irf2a Danio rerio ENSDARG00000007387 I 0.752
Myotis_brandtii_IRF1_10032556 Myotis brandtii Myotis_brandtii_IRF1_10032556 I 0.981
Myotis_brandtii_IRF2_10027054 Myotis brandtii Myotis_brandtii_IRF2_10027054 I 0.771
Ogr17358 Ophisaurus gracilis Ogr17358 I 0.752
Pvit_12337 Pogona vitticeps Pvit_12337 I 0.752
Pvit_14395 Pogona vitticeps Pvit_14395 I 0.829
Tal_R004238 Tyto alba Tal_R004238 I 0.924
Tal_R005926 Tyto alba Tal_R005926 I 0.790
txndc15 Danio rerio ENSDARG00000043249 I 0.771