IRF4 (Homo sapiens)
IRF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00605 (IRF) IPR001346 ENSG00000137265 T244081_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
IRF4
M03334_2.00		 Homo sapiens
HCGAAACCGAAACYW
WRGTTTCGGTTTCGD		 SELEX
Jolma et al.(2013)
IRF4_1		 (Direct) (Direct)
IRF4
M05539_2.00		 Homo sapiens
NYGAAACYGAAACYN
NRGTTTCRGTTTCRN		 SELEX
Yin et al.(2017)
IRF4_FL_HT-SELEX		 (Direct) (Direct)
IRF4
M05540_2.00		 Homo sapiens
NYGAAASYGAWASHN
NDSTWTCRSTTTCRN		 SELEX
Yin et al.(2017)
IRF4_FL_Methyl-HT-SELEX		 (Direct) (Direct)
IRF4
M07978_2.00		 Homo sapiens
DNDVNNGWWVTGAVWVWN
NWBWBTCABWWCNNBHNH		 ChIP-seq
Gerstein et al.(2012)
GM12878_IRF4_HudsonAlpha		 (Direct) (Direct)
IRF4
M09235_2.00		 Homo sapiens
NDWDRRGGAASTGARAVH
DBTYTCASTTCCYYHWHN		 Misc
Kulakovskiy et al.(2013)
IRF4_HUMAN.H11MO.0.A		 (Direct) (Direct)
IRF4
M09595_2.00		 Homo sapiens
HNYGAAASYD
HRSTTTCRND		 Misc
Heinz et al.(2010)
GM12878-IRF4_GSE32465		 (Direct) (Direct)
IRF4
M10885_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF4_07		 (Direct) (Direct)
IRF4
M10886_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF4_08		 (Direct) (Direct)
IRF4
M10887_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF4_Q5_01		 (Direct) (Direct)
IRF4
M10888_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF4_Q5		 (Direct) (Direct)
IRF4
M10889_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF4_Q6		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Irf4
M00175_2.00 		Mus musculus
NNNYGAWASN
NSTWTCRNNN		 PBM
Badis et al.(2009)
Irf4_3476 		0.990 0.990
Irf4
M09243_2.00 		Mus musculus
NDAWVVRGAASTGARAVH
DBTYTCASTTCYBBWTHN		 Misc
Kulakovskiy et al.(2013)
IRF4_MOUSE.H11MO.0.A 		0.990 0.990
IRF8
M03335_2.00 		Homo sapiens
HCGAAACYGAAACY
RGTTTCRGTTTCGD		 SELEX
Jolma et al.(2013)
IRF8_1 		0.810 0.810
IRF8
M03336_2.00 		Homo sapiens
HCGAAACCGAAACT
AGTTTCGGTTTCGD		 SELEX
Jolma et al.(2013)
IRF8_2 		0.810 0.810
IRF8
M05541_2.00 		Homo sapiens
NYGAAASYGAAASHN
NDSTTTCRSTTTCRN		 SELEX
Yin et al.(2017)
IRF8_eDBD_HT-SELEX 		0.810 0.810
IRF8
M05543_2.00 		Homo sapiens
NCGAAACYGAAACYN
NRGTTTCRGTTTCGN		 SELEX
Yin et al.(2017)
IRF8_FL_HT-SELEX 		0.810 0.810
IRF8
M09236_2.00 		Homo sapiens
NDDDRRGGAASTGAAASYNN
NNRSTTTCASTTCCYYHHHN		 Misc
Kulakovskiy et al.(2013)
IRF8_HUMAN.H11MO.0.B 		0.810 0.810
IRF8
M10890_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ICSBP_Q6 		0.810 0.810
IRF8
M10891_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF8_Q6 		0.810 0.810
IRF8
M05542_2.00 		Homo sapiens
NYGAAASYGAAASYN
NRSTTTCRSTTTCRN		 SELEX
Yin et al.(2017)
IRF8_eDBD_Methyl-HT-SELEX 		0.810 0.810
IRF8
M05544_2.00 		Homo sapiens
NYGAAASYGAAACYD
HRGTTTCRSTTTCRN		 SELEX
Yin et al.(2017)
IRF8_FL_Methyl-HT-SELEX 		0.810 0.810
Irf8
M09246_2.00 		Mus musculus
NDDDRRGGAASTGAAASYNN
NNRSTTTCASTTCCYYHHHN		 Misc
Kulakovskiy et al.(2013)
IRF8_MOUSE.H11MO.0.A 		0.790 0.790
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000370343 IRF 23 128
ENSP00000436094 IRF 23 128

Links

Other IRF family TFs
Other Homo sapiens TFs

157 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
AAEL001347 Aedes aegypti AAEL001347 N
AATE011073 Anopheles atroparvus AATE011073 N
AATE011230 Anopheles atroparvus AATE011230 N
ACEP15165 Atta cephalotes ACEP15165 N
ACHR000032 Anopheles christyi ACHR000032 N
ACHR010096 Anopheles christyi ACHR010096 N
ACOM033895 Anopheles coluzzii ACOM033895 N
ACUA000836 Anopheles culicifacies ACUA000836 N
ACUA024277 Anopheles culicifacies ACUA024277 N
ADAC008697 Anopheles darlingi ADAC008697 N
ADAC009393 Anopheles darlingi ADAC009393 N
AEPI009636 Anopheles epiroticus AEPI009636 N
AFAF002449 Anopheles farauti AFAF002449 N
AFAF002772 Anopheles farauti AFAF002772 N
AFUN010373 Anopheles funestus AFUN010373 N
AGAP012950 Anopheles gambiae AGAP012950 N
AMAM000172 Anopheles maculatus AMAM000172 N
AMEC000479 Anopheles melas AMEC000479 N
AMEC003904 Anopheles melas AMEC003904 N
AMEM008406 Anopheles merus AMEM008406 N
AMIN002198 Anopheles minimus AMIN002198 N
AQUA006477 Anopheles quadriannulatus AQUA006477 N
ASIS012990 Anopheles sinensis ASIS012990 N
Cflo_10942--XP_001121936.1_APIME Camponotus floridanus Cflo_10942--XP_001121936.1_APIME N
CG4374 Drosophila melanogaster FBgn0039078 N
CLEC005025 Cimex lectularius CLEC005025 N
CLEC005028 Cimex lectularius CLEC005028 N
CPIJ015425 Culex quinquefasciatus CPIJ015425 N
CpipJ_CPIJ015425 Culex pipiens CpipJ_CPIJ015425 N
DAPPUDRAFT_9525 Daphnia pulex DAPPUDRAFT_9525 N
GA18142 Drosophila pseudoobscura FBgn0078150 N
GB52523 Apis mellifera GB52523 N
GD18382 Drosophila simulans FBgn0189909 N
GE23956 Drosophila yakuba FBgn0241098 N
GF18765 Drosophila ananassae FBgn0095782 N
GG12435 Drosophila erecta FBgn0104723 N
GH20801 Drosophila grimshawi FBgn0128264 N
GI10710 Drosophila mojavensis FBgn0133474 N
GJ23125 Drosophila virilis FBgn0210227 N
GK13158 Drosophila willistoni FBgn0215167 N
GL13850 Drosophila persimilis FBgn0151455 N
GM23566 Drosophila sechellia FBgn0178432 N
HHAL000145-PA Halyomorpha halys HHAL000145-PA N
HMEL006238 Heliconius melpomene HMEL006238 N
KGM_19023 Danaus plexippus KGM_19023 N
L798_13006 Zootermopsis nevadensis L798_13006 N
LCUP001485 Lucilia cuprina LCUP001485 N
LDEC003260 Leptinotarsa decemlineata LDEC003260 N
LLOJ002004 Lutzomyia longipalpis LLOJ002004 N
MCINX016666 Melitaea cinxia MCINX016666 N
MDOA009050 Musca domestica MDOA009050 N
NV22259 Nasonia vitripennis NV22259 N
PHUM535390 Pediculus humanus PHUM535390 N
PPAI008603 Phlebotomus papatasi PPAI008603 N
SINV21477 Solenopsis invicta SINV21477 N
TC013857 Tribolium castaneum TC013857 N
YQE_03596 Dendroctonus ponderosae YQE_03596 N