NFATC1 (Homo sapiens)
Rel

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00554 (RHD_DNA_bind) IPR011539 ENSG00000131196 T317173_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
NFATC1
M02747_2.00		 Homo sapiens
DTTCCRYGGAA
TTCCRYGGAAH		 SELEX
Jolma et al.(2010)
NFATc1_dimer		 (Direct) (Direct)
NFATC1
M02748_2.00		 Homo sapiens
GGAANDTTCC
GGAAHNTTCC		 SELEX
Jolma et al.(2010)
NFATc1_dimer_type2		 (Direct) (Direct)
NFATC1
M02749_2.00		 Homo sapiens
WDTTTCCAY
RTGGAAAHW		 SELEX
Jolma et al.(2010)
NFATc1_monomer		 (Direct) (Direct)
NFATC1
M03449_2.00		 Homo sapiens
HKGRAAADDNWBTTTCCAYN
NRTGGAAAVWNHHTTTYCMD		 SELEX
Jolma et al.(2013)
NFATC1_1		 (Direct) (Direct)
NFATC1
M03450_2.00		 Homo sapiens
TTTCCAYWRYGGAAA
TTTCCRYWRTGGAAA		 SELEX
Jolma et al.(2013)
NFATC1_2		 (Direct) (Direct)
NFATC1
M03451_2.00		 Homo sapiens
NTTTCCATGGAAAN
NTTTCCATGGAAAN		 SELEX
Jolma et al.(2013)
NFATC1_3		 (Direct) (Direct)
NFATC1
M05711_2.00		 Homo sapiens
NTTTCCATGGAAAN
NTTTCCATGGAAAN		 SELEX
Yin et al.(2017)
NFATC1_eDBD_HT-SELEX_1		 (Direct) (Direct)
NFATC1
M05712_2.00		 Homo sapiens
NTTTCCRYNNRYGGAAAN
NTTTCCRYNNRYGGAAAN		 SELEX
Yin et al.(2017)
NFATC1_eDBD_HT-SELEX_2		 (Direct) (Direct)
NFATC1
M05713_2.00		 Homo sapiens
NTTTCCRYGGAAAN
NTTTCCRYGGAAAN		 SELEX
Yin et al.(2017)
NFATC1_eDBD_Methyl-HT-SELEX_1		 (Direct) (Direct)
NFATC1
M05714_2.00		 Homo sapiens
NTTTCCRYNNRYGGAAAN
NTTTCCRYNNRYGGAAAN		 SELEX
Yin et al.(2017)
NFATC1_eDBD_Methyl-HT-SELEX_2		 (Direct) (Direct)
NFATC1
M09349_2.00		 Homo sapiens
HBYHWBWBTTTCCWB
VWGGAAAVWVWDRVD		 Misc
Kulakovskiy et al.(2013)
NFAC1_HUMAN.H11MO.0.B		 (Direct) (Direct)
NFATC1
M09625_2.00		 Homo sapiens
WBTTTCCAYY
RRTGGAAAVW		 Misc
Heinz et al.(2010)
Jurkat-NFATC1_Jolma_et_al.		 (Direct) (Direct)
NFATC1
M11232_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFAT2_Q4		 (Direct) (Direct)
NFATC1
M11233_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFAT2_Q5_01		 (Direct) (Direct)
NFATC1
M11234_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFAT2_Q5		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
NFATC1
M02444_2.00 		Monodelphis domestica
NNDTTCCDNN
NNHGGAAHNN		 PBM
Weirauch et al.(2014)
pTH8401 		0.944 0.944
Nfatc1
M09360_2.00 		Mus musculus
KABTCANWBTTTCCW
WGGAAAVWNTGAVTM		 Misc
Kulakovskiy et al.(2013)
NFAC1_MOUSE.H11MO.0.A 		0.910 0.910
NFATC1
M02443_2.00 		Meleagris gallopavo
NNTTTCCRNN
NNYGGAAANN		 PBM
Weirauch et al.(2014)
pTH8315 		0.916 0.916
nfatc1
M02446_2.00 		Xenopus tropicalis
NNTTTCCRNN
NNYGGAAANN		 PBM
Weirauch et al.(2014)
pTH8557 		0.895 0.895
NFATC3
M02440_2.00 		Homo sapiens
DNTTTCCRNN
NNYGGAAANH		 PBM
Weirauch et al.(2014)
pTH9192 		0.839 0.839
NFATC3
M05693_2.00 		Homo sapiens
WNTTTCCRYN
NRYGGAAANW		 SELEX
Yin et al.(2017)
NFATC3_eDBD_HT-SELEX_1 		0.839 0.839
NFATC3
M05694_2.00 		Homo sapiens
NTTTCCATGGAAAN
NTTTCCATGGAAAN		 SELEX
Yin et al.(2017)
NFATC3_eDBD_HT-SELEX_2 		0.860 0.860
NFATC3
M05695_2.00 		Homo sapiens
DYGGAAANNNNNNNTTTCCRH
DYGGAAANNNNNNNTTTCCRH		 SELEX
Yin et al.(2017)
NFATC3_eDBD_HT-SELEX_3 		0.839 0.839
NFATC3
M09343_2.00 		Homo sapiens
RDTTTTCCA
TGGAAAAHY		 Misc
Kulakovskiy et al.(2013)
NFAC3_HUMAN.H11MO.0.B 		0.839 0.839
Nfatc3
M09359_2.00 		Mus musculus
RDTTTTCCA
TGGAAAAHY		 Misc
Kulakovskiy et al.(2013)
NFAC3_MOUSE.H11MO.0.B 		0.839 0.839
NFATC3
M11217_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFAT4_Q3 		0.839 0.839
NFATC3
M11218_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFAT4_Q5 		0.839 0.839
NFATC3
M05696_2.00 		Homo sapiens
WNTTTCCRYN
NRYGGAAANW		 SELEX
Yin et al.(2017)
NFATC3_eDBD_Methyl-HT-SELEX_1 		0.860 0.860
NFATC3
M05697_2.00 		Homo sapiens
NTTTCCRYGGAAAN
NTTTCCRYGGAAAN		 SELEX
Yin et al.(2017)
NFATC3_eDBD_Methyl-HT-SELEX_2 		0.839 0.839
NFATC3
M05698_2.00 		Homo sapiens
RYGGAAANHNNNDNTTTCCRY
RYGGAAANHNNNDNTTTCCRY		 SELEX
Yin et al.(2017)
NFATC3_eDBD_Methyl-HT-SELEX_3 		0.839 0.839
Nfatc2
M09357_2.00 		Mus musculus
NWTTTTCCW
WGGAAAAWN		 Misc
Kulakovskiy et al.(2013)
NFAC2_MOUSE.H11MO.0.C 		0.830 0.830
NFATC2
M02441_2.00 		Homo sapiens
WNTTTCCRHN
NDYGGAAANW		 PBM
Weirauch et al.(2014)
pTH9196 		0.810 0.810
NFATC2
M05705_2.00 		Homo sapiens
DTTTCCATGGAAAM
KTTTCCATGGAAAH		 SELEX
Yin et al.(2017)
NFATC2_eDBD_HT-SELEX_1 		0.810 0.810
NFATC2
M05706_2.00 		Homo sapiens
NTTTCCRYNNRYGGAAAN
NTTTCCRYNNRYGGAAAN		 SELEX
Yin et al.(2017)
NFATC2_eDBD_HT-SELEX_2 		0.810 0.810
NFATC2
M09346_2.00 		Homo sapiens
NWTTTTCCW
WGGAAAAWN		 Misc
Kulakovskiy et al.(2013)
NFAC2_HUMAN.H11MO.0.B 		0.810 0.810
NFATC2
M11221_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFAT1_Q4 		0.810 0.810
NFATC2
M11222_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFAT1_Q5 		0.810 0.810
NFATC2
M11223_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFAT1_Q6 		0.810 0.810
NFATC2
M08462_2.00 		Homo sapiens
TTTTCCA
TGGAAAA		 COMPILED
Mathelier et al.(2014)
MA0152.1 		0.810 0.810
NFATC2
M05707_2.00 		Homo sapiens
NTTTCCGCGGAAAN
NTTTCCGCGGAAAN		 SELEX
Yin et al.(2017)
NFATC2_eDBD_Methyl-HT-SELEX_1 		0.810 0.810
NFATC2
M05708_2.00 		Homo sapiens
NTTTCCRYNNRYGGAAAN
NTTTCCRYNNRYGGAAAN		 SELEX
Yin et al.(2017)
NFATC2_eDBD_Methyl-HT-SELEX_2 		0.810 0.810
NFATC4
M01306_2.00 		Homo sapiens
NNNWWWVYRN
NYRBWWWNNN		 PBM
Lambert et al.(2019)
pTH9347 		0.800 0.800
NFATC4
M05701_2.00 		Homo sapiens
DBTTTCCRYN
NRYGGAAAVH		 SELEX
Yin et al.(2017)
NFATC4_eDBD_HT-SELEX_1 		0.800 0.800
NFATC4
M05702_2.00 		Homo sapiens
NKTTCCATGGAAMV
BKTTCCATGGAAMN		 SELEX
Yin et al.(2017)
NFATC4_eDBD_HT-SELEX_2 		0.800 0.800
NFATC4
M09345_2.00 		Homo sapiens
HNDBTTTCCN
NGGAAAVHND		 Misc
Kulakovskiy et al.(2013)
NFAC4_HUMAN.H11MO.0.C 		0.790 0.790
Nfatc4
M09354_2.00 		Mus musculus
HNDBTTTCCN
NGGAAAVHND		 Misc
Kulakovskiy et al.(2013)
NFAC4_MOUSE.H11MO.0.C 		0.790 0.790
NFATC4
M11219_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFAT3_Q3_01 		0.790 0.790
NFATC4
M11220_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NFAT3_Q3 		0.790 0.790
NFATC4
M05703_2.00 		Homo sapiens
DNTTTCCRYN
NRYGGAAANH		 SELEX
Yin et al.(2017)
NFATC4_eDBD_Methyl-HT-SELEX_1 		0.790 0.790
NFATC4
M05704_2.00 		Homo sapiens
NKTTCCRYGGAAMN
NKTTCCRYGGAAMN		 SELEX
Yin et al.(2017)
NFATC4_eDBD_Methyl-HT-SELEX_2 		0.790 0.790
ENSTNIG00000018271
M02445_2.00 		Tetraodon nigroviridis
DNDTTCCRNN
NNYGGAAHNH		 PBM
Weirauch et al.(2014)
pTH9005 		0.755 0.755
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000253506 Rel 428 588
ENSP00000316553 Rel 415 575
ENSP00000327850 Rel 415 575
ENSP00000380892 Rel 1 116
ENSP00000389377 Rel 428 588
ENSP00000439992 Rel 1 116
ENSP00000442435 Rel 428 588
ENSP00000466194 Rel 428 588
ENSP00000466489 Rel 415 575
ENSP00000467181 Rel 415 575
ENSP00000468111 Rel 428 588

Links

Other Rel family TFs
Other Homo sapiens TFs

247 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
A1O9_01300 Exophiala aquamarina A1O9_01300 I 0.000
AB08968.1 Alternaria brassicicola AB08968.1 I 0.000
AFUA_2G02540 Aspergillus fumigatus CADAFUAG00003598 I 0.000
ANIA_04562 Aspergillus nidulans CADANIAG00005876 D 0.000
ARB_03451 Arthroderma benhamiae ARB_03451 I 0.000
ATEG_06925 Aspergillus terreus CADATEAG00003197 I 0.000
BAUCODRAFT_23289 Baudoinia compniacensis BAUCODRAFT_23289 I 0.000
CADAFLAG00007235 Aspergillus flavus CADAFLAG00007235 I 0.000
CADANGAG00005877 Aspergillus niger CADANGAG00005877 I 0.000
CHGG_06554 Chaetomium globosum CHGG_06554 I 0.000
CMQ_4918 Grosmannia clavigera CMQ_4918 I 0.000
COCC4DRAFT_125759 Bipolaris maydis COCC4DRAFT_125759 I 0.000
COCCADRAFT_29461 Bipolaris zeicola COCCADRAFT_29461 I 0.000
COCMIDRAFT_108054 Bipolaris oryzae COCMIDRAFT_108054 I 0.000
COCSADRAFT_86485 Bipolaris sorokiniana COCSADRAFT_86485 I 0.000
COCVIDRAFT_20419 Bipolaris victoriae COCVIDRAFT_20419 I 0.000
COCVIDRAFT_30018 Bipolaris victoriae COCVIDRAFT_30018 I 0.000
CTHT_0012120 Chaetomium thermophilum CTHT_0012120 I 0.000
DOTSEDRAFT_48303 Dothistroma septosporum DOTSEDRAFT_48303 I 0.000
EPUS_07397 Endocarpon pusillum EPUS_07397 I 0.000
estExt_Genewise1.C_20182 Mycosphaerella fijiensis estExt_Genewise1.C_20182 I 0.000
estExt_Genewise1Plus.C_40021 Cochliobolus heterostrophus C5 estExt_Genewise1Plus.C_40021 I 0.000
e_gw1.00771.352.1 Aspergillus carbonarius e_gw1.00771.352.1 I 0.000
e_gw1.13.356.1 Mycosphaerella graminicola e_gw1.13.356.1 I 0.000
GMDG_07872 Pseudogymnoascus destructans GMDG_07872 I 0.000
H101_05542 Trichophyton interdigitale H101_05542 I 0.000
H102_08445 Trichophyton rubrum H102_08445 I 0.000
HMPREF1624_04787 Sporothrix schenckii HMPREF1624_04787 I 0.000
LEMA_P113690.1 Leptosphaeria maculans LEMA_P113690.1 I 0.000
M7I_2756 Glarea lozoyensis M7I_2756 I 0.000
MAPG_10727 Magnaporthe poae MAPG_10727 I 0.000
MBM_06265 Marssonina brunnea MBM_06265 I 0.000
MCYG_03346 Microsporum canis MCYG_03346 I 0.000
MCYG_03346 Arthroderma otae MCYG_03346 I 0.000
MGYG_00508 Microsporum gypseum MGYG_00508 I 0.000
MYCFIDRAFT_49331 Pseudocercospora fijiensis MYCFIDRAFT_49331 I 0.000
Mycgr3G51498 Zymoseptoria tritici Mycgr3G51498 I 0.000
MYCTH_2298160 Myceliophthora thermophila MYCTH_2298160 I 0.000
OIDMADRAFT_110220 Oidiodendron maius OIDMADRAFT_110220 I 0.000
PAAG_05122 Paracoccidioides sp lutzii PAAG_05122 I 0.000
PDE_05394 Penicillium oxalicum PDE_05394 I 0.000
PMAA_045020 Penicillium marneffei PMAA_045020 I 0.000
PMAA_045020 Talaromyces marneffei PMAA_045020 I 0.000
PODANS_1_20350 Podospora anserina PODANS_1_20350 I 0.000
PTRG_07150 Pyrenophora triticirepentis PTRG_07150 I 0.000
PTT_08596 Pyrenophora teres PTT_08596 I 0.000
PV05_09803 Exophiala xenobiotica PV05_09803 I 0.000
PV08_01459 Exophiala spinifera PV08_01459 I 0.000
PV11_09617 Exophiala sideris PV11_09617 I 0.000
PVAR5_0698 Byssochlamys spectabilis PVAR5_0698 I 0.000
SBOR_5107 Sclerotinia borealis SBOR_5107 I 0.000
SETTUDRAFT_111603 Setosphaeria turcica SETTUDRAFT_111603 I 0.000
SNOG_00166 Stagonospora nodorum SNOG_00166 I 0.000
SNOG_00166 Phaeosphaeria nodorum SNOG_00166 I 0.000
TEQG_00858 Trichophyton equinum TEQG_00858 I 0.000
TESG_06189 Trichophyton tonsurans TESG_06189 I 0.000
TRIATDRAFT_300980 Trichoderma atroviride TRIATDRAFT_300980 I 0.000
TRIREDRAFT_74576 Trichoderma reesei TRIREDRAFT_74576 I 0.000
TRV_06106 Trichophyton verrucosum TRV_06106 I 0.000
TSTA_034220 Talaromyces stipitatus TSTA_034220 I 0.000
UCREL1_7025 Eutypa lata UCREL1_7025 I 0.000
UCRNP2_115 Neofusicoccum parvum UCRNP2_115 I 0.000
V499_08520 Pseudogymnoascus pannorum V499_08520 I 0.000
VHEMI07796 Torrubiella hemipterigena VHEMI07796 I 0.000