MLX (Homo sapiens)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSG00000108788 T034260_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
MLX
M02779_2.00		 Homo sapiens
RTCACGTGAY
RTCACGTGAY		 SELEX
Jolma et al.(2013)
MLX_1		 (Direct) (Direct)
MLX
M04080_2.00		 Homo sapiens
NCACGTGN
NCACGTGN		 SELEX
Yin et al.(2017)
MLX_eDBD_HT-SELEX		 (Direct) (Direct)
MLX
M04081_2.00		 Homo sapiens
NCACRTGV
BCAYGTGN		 SELEX
Yin et al.(2017)
MLX_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)
MLX
M04082_2.00		 Homo sapiens
NVCACGTGVYN
NRBCACGTGBN		 SELEX
Yin et al.(2017)
MLX_FL_HT-SELEX		 (Direct) (Direct)
MLX
M04083_2.00		 Homo sapiens
NDBCACRTGBV
BVCAYGTGVHN		 SELEX
Yin et al.(2017)
MLX_FL_Methyl-HT-SELEX		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Mlx
M00752_2.00 		Mus musculus
CACGTGNNN
NNNCACGTG		 PBM
Weirauch et al.(2013)
pTH2882 		0.914 1.000
Mlx
M01721_2.00 		Mus musculus
NCRCGTGNNN
NNNCACGYGN		 PBM
Weirauch et al.(2014)
pTH5070 		0.914 1.000
Mlx
M02815_2.00 		Mus musculus
RTCACGTGAY
RTCACGTGAY		 SELEX
Jolma et al.(2013)
Mlx_1 		0.914 1.000
MLX
M01114_2.00 		Monodelphis domestica
NNNCACGTGN
NCACGTGNNN		 PBM
Lambert et al.(2019)
pTH11463 		0.914 0.982
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000246912 bHLH 130 188
ENSP00000320913 bHLH 46 104
ENSP00000416627 bHLH 76 134
ENSP00000464697 bHLH 100 158

Links

Other bHLH family TFs
Other Homo sapiens TFs

52 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CBN18755 Caenorhabditis brenneri CBN18755 N
CBG23699 Caenorhabditis briggsae CBG23699 N
CRE11350 Caenorhabditis remanei CRE11350 N