CLOCK (Homo sapiens)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSG00000134852 T034288_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
CLOCK
M02789_2.00		 Homo sapiens
DACACGTGYH
DRCACGTGTH		 SELEX
Jolma et al.(2013)
CLOCK_1		 (Direct) (Direct)
CLOCK
M04129_2.00		 Homo sapiens
NMCACGTGYN
NRCACGTGKN		 SELEX
Yin et al.(2017)
CLOCK_eDBD_HT-SELEX		 (Direct) (Direct)
CLOCK
M04130_2.00		 Homo sapiens
NRCRCRTGBH
DVCAYGYGYN		 SELEX
Yin et al.(2017)
CLOCK_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)
CLOCK
M08728_2.00		 Homo sapiens
DBBBCAYKTGNNHB
VDNNCAMRTGVVVH		 Misc
Kulakovskiy et al.(2013)
CLOCK_HUMAN.H11MO.0.C		 (Direct) (Direct)
CLOCK
M09849_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CLOCK_Q6		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Clock
M01735_2.00 		Mus musculus
NNCAYRTGNN
NNCAYRTGNN		 PBM
Weirauch et al.(2014)
pTH5056 		0.914 1.000
Clock
M08760_2.00 		Mus musculus
DBBBCAYKTGNNHB
VDNNCAMRTGVVVH		 Misc
Kulakovskiy et al.(2013)
CLOCK_MOUSE.H11MO.0.C 		0.914 1.000
Clock
M09473_2.00 		Mus musculus
CACGTGNN
NNCACGTG		 Misc
Heinz et al.(2010)
Liver-Clock_GSE39860 		0.914 1.000
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000308741 bHLH 35 85
ENSP00000370723 bHLH 35 85
ENSP00000396649 bHLH 35 85
ENSP00000426983 bHLH 35 85

Links

Other bHLH family TFs
Other Homo sapiens TFs

78 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ACYPI49959 Acyrthosiphon pisum ACYPI49959 N
AAEL003861 Aedes aegypti AAEL003861 N
AAEL013830 Aedes aegypti AAEL013830 N
AALB000009 Anopheles albimanus AALB000009 N
AARA009523 Anopheles arabiensis AARA009523 N
AATE014935 Anopheles atroparvus AATE014935 N
ACHR009279 Anopheles christyi ACHR009279 N
ACOM040573 Anopheles coluzzii ACOM040573 N
ACUA000016 Anopheles culicifacies ACUA000016 N
ADAC010344 Anopheles darlingi ADAC010344 N
ADIR011406 Anopheles dirus ADIR011406 N
AEPI007740 Anopheles epiroticus AEPI007740 N
AFAF001139 Anopheles farauti AFAF001139 N
AFUN006562 Anopheles funestus AFUN006562 N
AGAP008959 Anopheles gambiae AGAP008959 N
AMAM022587 Anopheles maculatus AMAM022587 N
AMEC002045 Anopheles melas AMEC002045 N
AMIN009404 Anopheles minimus AMIN009404 N
AQUA002266 Anopheles quadriannulatus AQUA002266 N
ASIS009839 Anopheles sinensis ASIS009839 N
ASTEI01951 Anopheles stephensi ASTEI01951 N
GB51195 Apis mellifera GB51195 N
Cflo_04314--XP_623488.2_APIME Camponotus floridanus Cflo_04314--XP_623488.2_APIME N
CpipJ_CPIJ009317 Culex pipiens CpipJ_CPIJ009317 N
CPIJ009317 Culex quinquefasciatus CPIJ009317 N
KGM_10128 Danaus plexippus KGM_10128 N
YQE_06249 Dendroctonus ponderosae YQE_06249 N
GF15850 Drosophila ananassae FBgn0092874 N
GG24800 Drosophila erecta FBgn0116930 N
GH11419 Drosophila grimshawi FBgn0118899 N
chinmo Drosophila melanogaster FBgn0086758 N
GI14585 Drosophila mojavensis FBgn0137336 N
chinmo Drosophila simulans FBgn0194496 N
GK15202 Drosophila willistoni FBgn0217207 N
Hsal_04970--XP_623488.2_APIME Harpegnathos saltator Hsal_04970--XP_623488.2_APIME N
HMEL015812 Heliconius melpomene HMEL015812 N
LDEC003069 Leptinotarsa decemlineata LDEC003069 N
LCUP005584 Lucilia cuprina LCUP005584 N
NV11135 Nasonia vitripennis NV11135 N
PHUM464690 Pediculus humanus PHUM464690 N
PPAI002026 Phlebotomus papatasi PPAI002026 N
TC013792 Tribolium castaneum TC013792 N
L798_02452 Zootermopsis nevadensis L798_02452 N