Usf (Drosophila melanogaster)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 FBgn0029711 T038438_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables E-box binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Is expressed in several structures, including embryonic/larval garland cell; extended germ band embryo; and spermatocyte. Human ortholog(s) of this gene implicated in cardiovascular system disease and type 2 diabetes mellitus. Orthologous to several human genes including USF2 (upstream transcription factor 2, c-fos interacting). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Usf
M05982_2.00		 Drosophila melanogaster
VYCACGTGRS
SYCACGTGRB		 B1H
Zhu et al.(2011)
Usf_SANGER_5_FBgn0029711		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
FBpp0070669 bHLH 255 343
FBpp0301043 bHLH 255 343

Links

Other bHLH family TFs
Other Drosophila melanogaster TFs

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6 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action