tcf4.S (Xenopus laevis)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00010 (HLH) IPR001092 XB-GENE-1011632 T051764_2.00 Misc (2018-Jan-19)

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Tcf4
M01750_2.00 		Mus musculus
VCAGVTGBN
NVCABCTGB		 PBM
Weirauch et al.(2014)
pTH5101 		0.914 0.981
TCF4
M02807_2.00 		Homo sapiens
HRCACCTGBN
NVCAGGTGYD		 SELEX
Jolma et al.(2013)
TCF4_1 		0.914 0.981
TCF4
M02808_2.00 		Homo sapiens
NVCACCTBBN
NVVAGGTGBN		 SELEX
Jolma et al.(2013)
TCF4_2 		0.884 0.962
TCF4
M02728_2.00 		Homo sapiens
RCACCTG
CAGGTGY		 SELEX
Jolma et al.(2010)
TCF4_dimer 		0.884 0.962
TCF4
M04214_2.00 		Homo sapiens
VCACCTGB
VCAGGTGB		 SELEX
Yin et al.(2017)
TCF4_eDBD_HT-SELEX 		0.914 0.981
Tcf4
M08775_2.00 		Mus musculus
HRCACCTGB
VCAGGTGYD		 Misc
Kulakovskiy et al.(2013)
ITF2_MOUSE.H11MO.0.B 		0.914 0.981
TCF4
M09461_2.00 		Homo sapiens
ASWTCAAAGRVN
NBYCTTTGAWST		 Misc
Heinz et al.(2010)
Hct116-Tcf4_SRA012054 		0.884 0.962
TCF4
M04215_2.00 		Homo sapiens
VCACCTGN
NCAGGTGB		 SELEX
Yin et al.(2017)
TCF4_eDBD_Methyl-HT-SELEX 		0.884 0.962
Tcf12
M01740_2.00 		Mus musculus
NVCAYCTGB
VCAGRTGBN		 PBM
Weirauch et al.(2014)
pTH5071 		0.882 0.923
TCF12
M04137_2.00 		Homo sapiens
VCACSTGB
VCASGTGB		 SELEX
Yin et al.(2017)
TCF12_eDBD_HT-SELEX 		0.882 0.923
Tcf12
M08062_2.00 		Mus musculus
RRCAGCTGNNN
NNNCAGCTGYY		 ChIP-seq
Mathelier et al.(2014)
MA0521.1 		0.882 0.923
TCF12
M07805_2.00 		Homo sapiens
NVDSCAGSTGB
VCASCTGSHBN		 ChIP-seq
Gerstein et al.(2012)
GM12878_TCF12_HudsonAlpha 		0.882 0.923
TCF12
M07806_2.00 		Homo sapiens
VCASCTGB
VCAGSTGB		 ChIP-seq
Gerstein et al.(2012)
H1-hESC_TCF12_HudsonAlpha 		0.912 0.942
TCF12
M08731_2.00 		Homo sapiens
CMCASCTGSH
DSCAGSTGKG		 Misc
Kulakovskiy et al.(2013)
HTF4_HUMAN.H11MO.0.A 		0.912 0.942
Tcf12
M08762_2.00 		Mus musculus
VMCASCTGSH
DSCAGSTGKB		 Misc
Kulakovskiy et al.(2013)
HTF4_MOUSE.H11MO.0.A 		0.882 0.923
TCF12
M09458_2.00 		Homo sapiens
NNVCAGCTGB
VCAGCTGBNN		 Misc
Heinz et al.(2010)
GM12878-Tcf12_GSE32465 		0.882 0.923
TCF12
M09858_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HEB_Q6 		0.912 0.942
TCF12
M09859_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HTF4_Q2 		0.882 0.923
TCF12
M09860_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TCF12_01 		0.882 0.923
TCF12
M09861_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TCF12_03 		0.882 0.923
TCF12
M09862_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TCF12_05 		0.882 0.923
TCF12
M04138_2.00 		Homo sapiens
NCAYCTGN
NCAGRTGN		 SELEX
Yin et al.(2017)
TCF12_eDBD_Methyl-HT-SELEX 		0.882 0.923
Tcf3
M00753_2.00 		Mus musculus
VCACCTGBN
NVCAGGTGB		 PBM
Weirauch et al.(2013)
pTH3866 		0.912 0.885
Tcf3
M01723_2.00 		Mus musculus
NNVCACSTGB
VCASGTGBNN		 PBM
Weirauch et al.(2014)
pTH4580 		0.882 0.865
Tcf3
M00118_2.00 		Mus musculus
VCAYCTGB
VCAGRTGB		 PBM
Badis et al.(2009)
Tcfe2a_3865 		0.882 0.865
TCF3
M02775_2.00 		Homo sapiens
NVCACCTGBN
NVCAGGTGBN		 SELEX
Jolma et al.(2013)
TCF3_1 		0.884 0.904
TCF3
M08710_2.00 		Homo sapiens
VVCASCTGCHN
NDGCAGSTGBB		 Misc
Kulakovskiy et al.(2013)
TFE2_HUMAN.H11MO.0.A 		0.884 0.904
Tcf3
M09465_2.00 		Mus musculus
ABWTCAAAGS
SCTTTGAWVT		 Misc
Heinz et al.(2010)
mES-Tcf3_GSE11724 		0.884 0.904
Tcf3
M09466_2.00 		Mus musculus
VCAGCTGBNN
NNVCAGCTGB		 Misc
Heinz et al.(2010)
proBcell-E2A_GSE21978 		0.854 0.885
TCF3
M09791_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E12_Q6 		0.854 0.885
TCF3
M09792_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2A_Q6_01 		0.884 0.904
TCF3
M09793_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2A_Q6_02 		0.884 0.904
TCF3
M09794_2.00 		Homo sapiens
VVVVMCACCTGCNBB
VVNGCAGGTGKBBBB		 Transfac
Matys et al.(2006)
V$E47_01 		0.884 0.904
TCF3
M09795_2.00 		Homo sapiens
NNKWRCACCTGYDNNN
NNNHRCAGGTGYWMNN		 Transfac
Matys et al.(2006)
V$E47_02 		0.884 0.904
Tcf3
M09886_2.00 		Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E47_05 		0.884 0.904
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
AAA78933 bHLH 8 61
AAA92049 bHLH 34 87
AAH86475 bHLH 505 558

Links

Other bHLH family TFs
Other Xenopus laevis TFs

214 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
A1O3_06180 Capronia epimyces A1O3_06180 N
PV04_10849 Capronia semiimmersa PV04_10849 N
PV07_08572 Cladophialophora immunda PV07_08572 N
PV07_12865 Cladophialophora immunda PV07_12865 N
A1O5_12014 Cladophialophora psammophila A1O5_12014 N
EPUS_00914 Endocarpon pusillum EPUS_00914 N
PV06_11815 Exophiala oligosperma PV06_11815 N
PV11_05146 Exophiala sideris PV11_05146 N
CMQ_7531 Grosmannia clavigera CMQ_7531 N
F503_08034 Ophiostoma piceae uamh F503_08034 N
Z518_05999 Rhinocladiella mackenziei Z518_05999 N
SAPIO_CDS5410 Scedosporium apiospermum SAPIO_CDS5410 N