HLF (Homo sapiens)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00170 (bZIP_1) IPR011616 ENSG00000108924 T059728_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
HLF
M02831_2.00		 Homo sapiens
NRTTAYRTAABN
NVTTAYRTAAYN		 SELEX
Jolma et al.(2013)
HLF_1		 (Direct) (Direct)
HLF
M04016_2.00		 Homo sapiens
RTKAYRTAAB
VTTAYRTMAY		 SELEX
Rodriguez-Martinez et al.(2017)
HLF.1		 (Direct) (Direct)
HLF
M04245_2.00		 Homo sapiens
NVTTRCRYAABN
NVTTRYGYAABN		 SELEX
Yin et al.(2017)
HLF_FL_HT-SELEX		 (Direct) (Direct)
HLF
M04246_2.00		 Homo sapiens
NVTTRCRYAABN
NVTTRYGYAABN		 SELEX
Yin et al.(2017)
HLF_FL_Methyl-HT-SELEX		 (Direct) (Direct)
HLF
M08786_2.00		 Homo sapiens
NRTTRYGTAAYMS
SKRTTACRYAAYN		 Misc
Kulakovskiy et al.(2013)
HLF_HUMAN.H11MO.0.C		 (Direct) (Direct)
HLF
M09937_2.00		 Homo sapiens
ATKRYGTAAY
RTTACRYMAT		 Transfac
Matys et al.(2006)
V$HLF_01		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Hlf
M02860_2.00 		Mus musculus
KRTTACGTAAYN
NRTTACGTAAYM		 SELEX
Jolma et al.(2013)
Hlf_1 		0.896 1.000
Hlf
M08815_2.00 		Mus musculus
VTTRTGYAABH
DVTTRCAYAAB		 Misc
Kulakovskiy et al.(2013)
HLF_MOUSE.H11MO.0.C 		0.896 1.000
Tef
M01803_2.00 		Mus musculus
NVTTRYVNNN
NNNBRYAABN		 PBM
Weirauch et al.(2014)
pTH5078 		0.847 0.794
TEF
M02849_2.00 		Homo sapiens
NRTTAYGTAAYN
NRTTACRTAAYN		 SELEX
Jolma et al.(2013)
TEF_1 		0.847 0.766
TEF
M02850_2.00 		Homo sapiens
NVTTAYGTAABN
NVTTACRTAABN		 SELEX
Jolma et al.(2013)
TEF_2 		0.847 0.766
TEF
M04325_2.00 		Homo sapiens
NRTTACGTAAYN
NRTTACGTAAYN		 SELEX
Yin et al.(2017)
TEF_eDBD_HT-SELEX 		0.847 0.766
TEF
M09983_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TEF_05 		0.847 0.794
TEF
M09984_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TEF_06 		0.847 0.794
TEF
M09985_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TEF_Q6 		0.847 0.794
TEF
M09986_2.00 		Homo sapiens
MTKAYGTAAY
RTTACRTMAK		 Transfac
Matys et al.(2006)
V$VBP_01 		0.847 0.794
TEF
M04326_2.00 		Homo sapiens
NRTTACRTAAYN
NRTTAYGTAAYN		 SELEX
Yin et al.(2017)
TEF_eDBD_Methyl-HT-SELEX 		0.847 0.794
Pdp1
M03645_2.00 		Drosophila melanogaster
VTTACGTAAB
VTTACGTAAB		 SELEX
Nitta et al.(2015)
Pdp1_1 		0.795 0.683
Pdp1
M03646_2.00 		Drosophila melanogaster
RTTACGTAAY
RTTACGTAAY		 SELEX
Nitta et al.(2015)
Pdp1_2 		0.795 0.683
For this family, TFs with SR scores > 0.782 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000226067 bZIP 224 286
ENSP00000402496 bZIP 139 201
ENSP00000460296 bZIP 139 201
ENSP00000460572 bZIP 139 201
ENSP00000461455 bZIP 164 227

Links

Other bZIP family TFs
Other Homo sapiens TFs

233 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSAMXG00000007122 Astyanax mexicanus ENSAMXG00000007122 I 0.000
CapteG19335 Capitella teleta CapteG19335 I 0.000
nfe2l2b Danio rerio ENSDARG00000089697 I 0.000
NFE2L3 Dasypus novemcinctus ENSDNOG00000012919 I 0.000
NFE2L3 Equus caballus ENSECAG00000021973 I 0.000
ENSGMOG00000004196 Gadus morhua ENSGMOG00000004196 I 0.000
nfe2l2a Gasterosteus aculeatus ENSGACG00000004470 I 0.000
HelroG89262 Helobdella robusta HelroG89262 I 0.000
ENSLACG00000013393 Latimeria chalumnae ENSLACG00000013393 I 0.000
ENSLACG00000009960 Latimeria chalumnae ENSLACG00000009960 I 0.000
ENSLOCG00000006972 Lepisosteus oculatus ENSLOCG00000006972 I 0.000
LotgiG118868 Lottia gigantea LotgiG118868 N 0.000
Ogr16304 Ophisaurus gracilis Ogr16304 I 0.000
ENSONIG00000008604 Oreochromis niloticus ENSONIG00000008604 I 0.000
ENSOANG00000009158 Ornithorhynchus anatinus ENSOANG00000009158 I 0.000
nfe2l2a Oryzias latipes ENSORLG00000017568 I 0.000
ENSPFOG00000014090 Poecilia formosa ENSPFOG00000014090 I 0.000
ENSSHAG00000017945 Sarcophilus harrisii ENSSHAG00000017945 I 0.000
nfe2l2a Takifugu rubripes ENSTRUG00000017486 I 0.000
nfe2l1a Takifugu rubripes ENSTRUG00000010088 I 0.000
tetur07g06850 Tetranychus urticae tetur07g06850 N 0.000
nfe2l2a Tetraodon nigroviridis ENSTNIG00000016959 I 0.000
nfe2l1a Tetraodon nigroviridis ENSTNIG00000003150 I 0.000
nfe2l2.L Xenopus laevis XB-GENE-17346208 I 0.000
nfe2.S Xenopus laevis XB-GENE-865028 I 0.000
nfe2l2.S Xenopus laevis XB-GENE-943932 I 0.000
nfe2 Xenopus tropicalis XB-GENE-483914 I 0.000
nfe2l2 Xenopus tropicalis XB-GENE-943926 I 0.000
ENSXMAG00000000450 Xiphophorus maculatus ENSXMAG00000000450 I 0.000