xbp-1 (Caenorhabditis elegans)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00170 (bZIP_1) IPR011616 WBGene00006959 T069403_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response. Acts upstream of with a positive effect on IRE1-mediated unfolded protein response and negative regulation of developmental process. Acts upstream of with a negative effect on age-dependent general metabolic decline. Is expressed in several structures, including intestine. Orthologous to human XBP1 (X-box binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
xbp-1
M00597_2.00		 Caenorhabditis elegans
NNNNHKACGTGDN
NHCACGTMDNNNN		 PBM
Narasimhan et al.(2015)
pTH10030		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.782 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00597_2.00 bZIP 51 115

DNA Binding Domains

Protein ID Domain From To Sequence
R74.3a bZIP 59 123
R74.3b bZIP 59 123
R74.3c bZIP 59 123

Links

Other bZIP family TFs
Other Caenorhabditis elegans TFs

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5 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action