ZNF281 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000162702 T095017_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ZNF281
M04509_2.00		 Homo sapiens
SCCCCTCCCCCM
KGGGGGAGGGGS		 SELEX
Yin et al.(2017)
ZNF281_eDBD_HT-SELEX		 (Direct) (Direct)
ZNF281
M04510_2.00		 Homo sapiens
RCCCMTCCCCCR
YGGGGGAKGGGY		 SELEX
Yin et al.(2017)
ZNF281_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)
ZNF281
M08321_2.00		 Homo sapiens
BNCCCCTCCCCC
GGGGGAGGGGNV		 ChIP-seq
Schmitges et al.(2016)
Q9Y2X9_1-4.RCADE		 (Direct) (Direct)
ZNF281
M08906_2.00		 Homo sapiens
BCCCCTCCCCCHNYN
NRNDGGGGGAGGGGV		 Misc
Kulakovskiy et al.(2013)
ZN281_HUMAN.H11MO.0.A		 (Direct) (Direct)
ZNF281
M10237_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ZFP281_01		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Zfp281
M00139_2.00 		Mus musculus
NHDCCCCCHH
DDGGGGGHDN		 PBM
Badis et al.(2009)
Zfp281_0973 		0.827 1.000
Zfp281
M08025_2.00 		Mus musculus
CCCCWCCCCCMVCHB
VDGBKGGGGGWGGGG		 ChIP-seq
Chen et al.(2011)
GSE11329_zfp281 		0.827 1.000
Zfp281
M08999_2.00 		Mus musculus
CCCCTCCCCCMMCBB
VVGKKGGGGGAGGGG		 Misc
Kulakovskiy et al.(2013)
ZN281_MOUSE.H11MO.0.A 		0.827 1.000
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000294740 C2H2 ZF 261 283
ENSP00000294740 C2H2 ZF 289 311
ENSP00000294740 C2H2 ZF 317 339
ENSP00000294740 C2H2 ZF 345 366
ENSP00000356321 C2H2 ZF 225 247
ENSP00000356321 C2H2 ZF 253 275
ENSP00000356321 C2H2 ZF 281 303
ENSP00000356321 C2H2 ZF 309 330
ENSP00000356322 C2H2 ZF 261 283
ENSP00000356322 C2H2 ZF 289 311
ENSP00000356322 C2H2 ZF 317 339
ENSP00000356322 C2H2 ZF 345 366

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

67 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Alligator_sinensis_CCG011250.1 Alligator sinensis Alligator_sinensis_CCG011250.1 I 0.813
ZNF148 Anolis carolinensis ENSACAG00000010047 I 0.757
ZNF281 Anolis carolinensis ENSACAG00000006286 I 0.808
Afo_R004007 Aptenodytes forsteri Afo_R004007 I 0.813
ENSAMXG00000006043 Astyanax mexicanus ENSAMXG00000006043 I 0.759
ENSAMXG00000006245 Astyanax mexicanus ENSAMXG00000006245 I 0.801
ENSAMXG00000015147 Astyanax mexicanus ENSAMXG00000015147 I 0.803
ENSP00000356322-D1 Bos grunniens ENSP00000356322-D1 I 0.801
Brh_R005182 Buceros rhinoceros Brh_R005182 I 0.813
ZNF281 Callithrix jacchus ENSCJAG00000005104 I 0.827
Aan_R014758 Calypte anna Aan_R014758 I 0.813
Cmyd_10021057 Chelonia mydas Cmyd_10021057 I 0.813
ENSCSAG00000000250 Chlorocebus sabaeus ENSCSAG00000000250 I 0.827
ZNF281 Choloepus hoffmanni ENSCHOG00000004074 I 0.827
znf281a Danio rerio ENSDARG00000000567 I 0.798
znf148 Danio rerio ENSDARG00000055106 I 0.757
znf281b Danio rerio ENSDARG00000035910 I 0.801
ZNF281 Dasypus novemcinctus ENSDNOG00000016981 I 0.827
Zfp281 Dipodomys ordii ENSDORG00000002833 I 0.825
ZNF281 Equus caballus ENSECAG00000024354 I 0.827
ZNF281 Erinaceus europaeus ENSEEUG00000011443 I 0.827
ZNF281 Felis catus ENSFCAG00000028447 I 0.827
ENSFALG00000014467 Ficedula albicollis ENSFALG00000014467 I 0.813
ENSGMOG00000001704 Gadus morhua ENSGMOG00000001704 I 0.786
ENSGMOG00000008854 Gadus morhua ENSGMOG00000008854 I 0.786
znf281a Gasterosteus aculeatus ENSGACG00000009536 I 0.784
znf281b Gasterosteus aculeatus ENSGACG00000006858 I 0.789
Gfo_R006633 Geospiza fortis Gfo_R006633 I 0.813
ZNF281 Gorilla gorilla ENSGGOG00000010349 I 0.827
ENSLACG00000014572 Latimeria chalumnae ENSLACG00000014572 I 0.810
ENSLACG00000006364 Latimeria chalumnae ENSLACG00000006364 I 0.757
ENSLOCG00000011584 Lepisosteus oculatus ENSLOCG00000011584 I 0.798
ENSP00000356322 Macaca fascicularis ENSP00000356322 I 0.827
ZNF281 Macaca mulatta ENSMMUG00000007334 I 0.827
ENSMEUG00000011709 Macropus eugenii ENSMEUG00000011709 I 0.825
ZNF281 Microcebus murinus ENSMICG00000001070 I 0.827
ZNF281 Monodelphis domestica ENSMODG00000012840 I 0.825
ENSMPUG00000019246 Mustela putorius furo ENSMPUG00000019246 I 0.827
Zfp281 Mus musculus ENSMUSG00000041483 D 0.827
ENSNLEG00000018067 Nomascus leucogenys ENSNLEG00000018067 I 0.827
Ogr00130 Ophisaurus gracilis Ogr00130 I 0.810
ENSONIG00000000839 Oreochromis niloticus ENSONIG00000000839 I 0.772
ENSONIG00000016453 Oreochromis niloticus ENSONIG00000016453 I 0.789
ZNF281 Ornithorhynchus anatinus ENSOANG00000004857 I 0.801
ZNF281 Oryctolagus cuniculus ENSOCUG00000010120 I 0.827
znf281a Oryzias latipes ENSORLG00000002799 I 0.783
znf281b Oryzias latipes ENSORLG00000005292 I 0.789
znf148 Oryzias latipes ENSORLG00000015950 I 0.759
ZNF281 Otolemur garnettii ENSOGAG00000010366 I 0.827
ZNF281 Pan troglodytes ENSPTRG00000015318 I 0.827
ENSPANG00000017386 Papio anubis ENSPANG00000017386 I 0.827
ENSPFOG00000008024 Poecilia formosa ENSPFOG00000008024 I 0.798
ENSPFOG00000000851 Poecilia formosa ENSPFOG00000000851 I 0.789
Pvit_14619 Pogona vitticeps Pvit_14619 I 0.808
Pvit_03082 Pogona vitticeps Pvit_03082 I 0.757
Zfp281 Rattus norvegicus ENSRNOG00000058643 I 0.827
ZNF281 Sus scrofa ENSSSCG00000010911 I 0.827
ZNF281 Taeniopygia guttata ENSTGUG00000004438 I 0.813
znf281a Takifugu rubripes ENSTRUG00000016619 I 0.786
znf281b Takifugu rubripes ENSTRUG00000008207 I 0.789
ENSTSYG00000007604 Tarsius syrichta ENSTSYG00000007604 I 0.827
znf281b Tetraodon nigroviridis ENSTNIG00000018917 I 0.789
znf281a Tetraodon nigroviridis ENSTNIG00000016430 I 0.774
ZNF281 Tursiops truncatus ENSTTRG00000004326 I 0.827
Tal_R010113 Tyto alba Tal_R010113 I 0.813
znf281 Xenopus tropicalis XB-GENE-5933312 I 0.813