lsy-2 (Caenorhabditis elegans)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 WBGene00003087 T131561_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Is expressed in several structures, including anal region; epithelial system; head; intestine; and nervous system. Orthologous to human ZNF148 (zinc finger protein 148). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
lsy-2
M00615_2.00		 Caenorhabditis elegans
NTACMGTANN
NNTACKGTAN		 PBM
Narasimhan et al.(2015)
pTH10810		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00615_2.00 C2H2 ZF 51 73
M00615_2.00 C2H2 ZF 79 101
M00615_2.00 C2H2 ZF 107 129

DNA Binding Domains

Protein ID Domain From To Sequence
F49H12.1a C2H2 ZF 78 100
F49H12.1a C2H2 ZF 106 128
F49H12.1a C2H2 ZF 134 156
F49H12.1b.1 C2H2 ZF 52 74
F49H12.1b.1 C2H2 ZF 80 102
F49H12.1b.1 C2H2 ZF 108 130
F49H12.1b.2 C2H2 ZF 52 74
F49H12.1b.2 C2H2 ZF 80 102
F49H12.1b.2 C2H2 ZF 108 130

Links

Other C2H2 ZF family TFs
Other Caenorhabditis elegans TFs

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49 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action