e2f1/2/3/6 (Ciona intestinalis)
E2F

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF02319 (E2F_TDP) IPR003316 ENSCING00000020227 T172492_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
E2f3
M00153_2.00 		Mus musculus
NNNNGCGSNN
NNSCGCNNNN		 PBM
Badis et al.(2009)
E2F3_3752 		0.754 0.754
E2F3
M02956_2.00 		Homo sapiens
RAAAAKGGCGCCAAAANN
NNTTTTGGCGCCMTTTTY		 SELEX
Jolma et al.(2013)
E2F3_1 		0.754 0.754
E2F3
M02957_2.00 		Homo sapiens
DAAAADGGCGCCMWWTTY
RAAWWKGGCGCCHTTTTH		 SELEX
Jolma et al.(2013)
E2F3_2 		0.754 0.754
E2F3
M02958_2.00 		Homo sapiens
NDTTTTGGCGCCAAAABH
DVTTTTGGCGCCAAAAHN		 SELEX
Jolma et al.(2013)
E2F3_3 		0.754 0.754
E2F3
M04701_2.00 		Homo sapiens
DWTTTGGCGCCAAAWH
DWTTTGGCGCCAAAWH		 SELEX
Yin et al.(2017)
E2F3_eDBD_HT-SELEX 		0.754 0.754
E2F3
M09031_2.00 		Homo sapiens
NDGGCGGGAAR
YTTCCCGCCHN		 Misc
Kulakovskiy et al.(2013)
E2F3_HUMAN.H11MO.0.A 		0.754 0.754
E2f3
M09038_2.00 		Mus musculus
DSGCGGGARV
BYTCCCGCSH		 Misc
Kulakovskiy et al.(2013)
E2F3_MOUSE.H11MO.0.A 		0.754 0.754
E2F3
M10454_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F1_Q6_01 		0.754 0.754
E2F3
M10455_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F3_Q6 		0.754 0.754
E2F3
M04702_2.00 		Homo sapiens
DTTTTGGCGCCAAAAH
DTTTTGGCGCCAAAAH		 SELEX
Yin et al.(2017)
E2F3_eDBD_Methyl-HT-SELEX 		0.754 0.754
E2f2
M00154_2.00 		Mus musculus
NDNNGCGSBN
NVSCGCNNHN		 PBM
Badis et al.(2009)
E2F2_1022 		0.738 0.738
ENSOANG00000014967
M01962_2.00 		Ornithorhynchus anatinus
NDSGCGCSHN
NDSGCGCSHN		 PBM
Weirauch et al.(2014)
pTH9382 		0.738 0.738
E2F3
M01964_2.00 		Taeniopygia guttata
NNSGCGCGMN
NKCGCGCSNN		 PBM
Weirauch et al.(2014)
pTH9288 		0.738 0.738
E2f2
M09039_2.00 		Mus musculus
GGCGCGMAWC
GWTKCGCGCC		 Misc
Kulakovskiy et al.(2013)
E2F2_MOUSE.H11MO.0.B 		0.738 0.738
ENSACAG00000013716
M01960_2.00 		Anolis carolinensis
HNVGCGCBND
HNVGCGCBND		 PBM
Weirauch et al.(2014)
pTH9221 		0.723 0.723
E2F2
M01961_2.00 		Homo sapiens
DNSGCGCSNH
DNSGCGCSNH		 PBM
Weirauch et al.(2014)
pTH9195 		0.723 0.723
E2F2
M02949_2.00 		Homo sapiens
AAAAATGGCGCCAAAAWD
HWTTTTGGCGCCATTTTT		 SELEX
Jolma et al.(2013)
E2F2_1 		0.723 0.723
E2F2
M02950_2.00 		Homo sapiens
VDTTTTGGCGCCAAAAHN
NDTTTTGGCGCCAAAAHB		 SELEX
Jolma et al.(2013)
E2F2_2 		0.723 0.723
E2F2
M02951_2.00 		Homo sapiens
AAAWWGGCGCCAWTTT
AAAWTGGCGCCWWTTT		 SELEX
Jolma et al.(2013)
E2F2_3 		0.723 0.723
E2F2
M04696_2.00 		Homo sapiens
GCGCGCGCSYW
WRSGCGCGCGC		 SELEX
Yin et al.(2017)
E2F2_eDBD_HT-SELEX_1 		0.723 0.723
E2F2
M04697_2.00 		Homo sapiens
NDWWDGGCGCCWWHWN
NWDWWGGCGCCHWWHN		 SELEX
Yin et al.(2017)
E2F2_eDBD_HT-SELEX_2 		0.723 0.723
E2F2
M09029_2.00 		Homo sapiens
GGCGCGMAWC
GWTKCGCGCC		 Misc
Kulakovskiy et al.(2013)
E2F2_HUMAN.H11MO.0.B 		0.723 0.723
E2F2
M04698_2.00 		Homo sapiens
SGBGSGCGCGS
SCGCGCSCVCS		 SELEX
Yin et al.(2017)
E2F2_eDBD_Methyl-HT-SELEX_1 		0.723 0.723
E2F2
M04699_2.00 		Homo sapiens
DWWWDGGCGCCAAAWH
DWTTTGGCGCCHWWWH		 SELEX
Yin et al.(2017)
E2F2_eDBD_Methyl-HT-SELEX_2 		0.723 0.723
E2F2
M01963_2.00 		Tupaia belangeri
WDVGCGCBHW
WDVGCGCBHW		 PBM
Weirauch et al.(2014)
pTH9291 		0.708 0.708
e_gw1.38.2.1
M01968_2.00 		Physcomitrella patens
NSGCGCBHHN
NDDVGCGCSN		 PBM
Weirauch et al.(2014)
pTH5707 		0.692 0.692
estExt_gwp_gw1.C_220046
M01225_2.00 		Physcomitrella patens
VGCGCBHHNN
NNDDVGCGCB		 PBM
Lambert et al.(2019)
pTH9809 		0.692 0.692
E2F4
M02961_2.00 		Homo sapiens
AATGGCGCCAAA
TTTGGCGCCATT		 SELEX
Jolma et al.(2013)
E2F4_1 		0.677 0.677
E2F4
M02962_2.00 		Homo sapiens
TTTGGCGCCAAA
TTTGGCGCCAAA		 SELEX
Jolma et al.(2013)
E2F4_2 		0.677 0.677
E2F4
M04707_2.00 		Homo sapiens
NWWKGGCGCCAAAW
WTTTGGCGCCMWWN		 SELEX
Yin et al.(2017)
E2F4_eDBD_HT-SELEX 		0.677 0.677
efl-1
M08110_2.00 		Caenorhabditis elegans
HNHNSGCGSSAAWWN
NWWTTSSCGCSNDND		 ChIP-seq
Mathelier et al.(2014)
MA0541.1 		0.677 0.677
E2F4
M08109_2.00 		Homo sapiens
NSGCGGGARVN
NBYTCCCGCSN		 ChIP-seq
Mathelier et al.(2014)
MA0470.1 		0.677 0.677
E2F4
M07942_2.00 		Homo sapiens
SGCGSGARDNNBNVN
NBNVNNHYTCSCGCS		 ChIP-seq
Gerstein et al.(2012)
HeLa-S3_E2F4_UCD 		0.677 0.677
E2F4
M07943_2.00 		Homo sapiens
SGCGGGARDNNBVVN
NBBVNNHYTCCCGCS		 ChIP-seq
Gerstein et al.(2012)
K562b_E2F4_UCD 		0.677 0.677
efl-1
M08197_2.00 		Caenorhabditis elegans
BGCGSSAAWW
WWTTSSCGCV		 ChIP-seq
Contrino et al.(2012)
Mw140 		0.677 0.677
E2F4
M09036_2.00 		Homo sapiens
VDRGGCGGGRVND
HNBYCCCGCCYHB		 Misc
Kulakovskiy et al.(2013)
E2F4_HUMAN.H11MO.0.A 		0.677 0.677
E2f4
M09037_2.00 		Mus musculus
NRDDGGCGGGRMNN
NNKYCCCGCCHHYN		 Misc
Kulakovskiy et al.(2013)
E2F4_MOUSE.H11MO.0.A 		0.677 0.677
efl-1
M09526_2.00 		Caenorhabditis elegans
WGCAARYGCGCTCYA
TRGAGCGCRYTTGCW		 Misc
Heinz et al.(2010)
cElegans-L1-EFL1_modEncode 		0.677 0.677
E2F4
M09524_2.00 		Homo sapiens
VGCGSGAADH
DHTTCSCGCB		 Misc
Heinz et al.(2010)
K562-E2F4_GSE31477 		0.677 0.677
E2F4
M10457_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F4_05 		0.677 0.677
E2F4
M10458_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F4_Q3 		0.677 0.677
E2F4
M10459_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F4_Q6 		0.677 0.677
E2F1
M02952_2.00 		Homo sapiens
WWDGGCGCCAAW
WTTGGCGCCHWW		 SELEX
Jolma et al.(2013)
E2F1_1 		0.662 0.662
E2F1
M02953_2.00 		Homo sapiens
WWKGGCGCCWWW
WWWGGCGCCMWW		 SELEX
Jolma et al.(2013)
E2F1_2 		0.662 0.662
E2F1
M02954_2.00 		Homo sapiens
WWWKGGCGCCMWWW
WWWKGGCGCCMWWW		 SELEX
Jolma et al.(2013)
E2F1_3 		0.662 0.662
E2F1
M02955_2.00 		Homo sapiens
AAWKGGCGCCAWTW
WAWTGGCGCCMWTT		 SELEX
Jolma et al.(2013)
E2F1_4 		0.662 0.662
E2F1
M04700_2.00 		Homo sapiens
NWWWDGGCGCCAAAWH
DWTTTGGCGCCHWWWN		 SELEX
Yin et al.(2017)
E2F1_FL_HT-SELEX 		0.662 0.662
E2FA
M06871_2.00 		Arabidopsis thaliana
NDDDGGCGCCAWWW
WWWTGGCGCCHHHN		 Dap-seq
OMalley et al.(2016)
E2FA_col_a 		0.662 0.662
E2FA
M06872_2.00 		Arabidopsis thaliana
DDWDGGCGCCAWAD
HTWTGGCGCCHWHH		 Dap-seq
OMalley et al.(2016)
E2FA_colamp_a 		0.662 0.662
E2FC
M06870_2.00 		Arabidopsis thaliana
AWDDDGGCGCCAAAR
YTTTGGCGCCHHHWT		 Dap-seq
OMalley et al.(2016)
E2FC_col_a 		0.662 0.662
E2FA
M08106_2.00 		Arabidopsis thaliana
NVGCGCCAHN
NDTGGCGCBN		 ChIP-seq
Mathelier et al.(2014)
MA1414.1 		0.662 0.662
E2F1
M07938_2.00 		Homo sapiens
VRRVNRVGCGSGMDS
SHKCSCGCBYNBYYB		 ChIP-seq
Gerstein et al.(2012)
HeLa-S3_E2F1_UCD 		0.662 0.662
E2F1
M09030_2.00 		Homo sapiens
NVNDGGCGGGARVN
NBYTCCCGCCHNBN		 Misc
Kulakovskiy et al.(2013)
E2F1_HUMAN.H11MO.0.A 		0.662 0.662
E2f1
M09041_2.00 		Mus musculus
NDDGGCGGGRVN
NBYCCCGCCHHN		 Misc
Kulakovskiy et al.(2013)
E2F1_MOUSE.H11MO.0.A 		0.662 0.662
E2f5
M09042_2.00 		Mus musculus
NGCGCSAAAN
NTTTSGCGCN		 Misc
Kulakovskiy et al.(2013)
E2F5_MOUSE.H11MO.0.B 		0.662 0.662
E2F1
M09521_2.00 		Homo sapiens
NNGGCGGGAA
TTCCCGCCNN		 Misc
Heinz et al.(2010)
Hela-E2F1_GSE22478 		0.662 0.662
E2F1
M10444_2.00 		Homo sapiens
THVGCGCGAAAAHKR
YMDTTTTCGCGCBDA		 Transfac
Matys et al.(2006)
V$E2F_01 		0.662 0.662
E2F1
M10445_2.00 		Homo sapiens
BHKSGCGCSAAA
TTTSGCGCSMDV		 Transfac
Matys et al.(2006)
V$E2F_03 		0.662 0.662
E2F1
M10446_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F1_01 		0.662 0.662
E2F1
M10447_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F1_02 		0.662 0.662
E2F1
M10448_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F1_Q3_01 		0.662 0.662
E2F1
M10449_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F1_Q3 		0.662 0.662
E2F1
M10450_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F1_Q4_01 		0.662 0.662
E2F1
M10451_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F1_Q4_02 		0.662 0.662
E2F1
M10452_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F1_Q4 		0.662 0.662
E2F1
M10453_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F1_Q6 		0.662 0.662
E2f
M08196_2.00 		Drosophila melanogaster
AAWWBSSCGSCAA
TTGSCGSSVWWTT		 ChIP-seq
Contrino et al.(2012)
Mf10 		0.646 0.646
GSPATT00020286001
M01965_2.00 		Paramecium tetraurelia
NNSGCGSBN
NVSCGCSNN		 PBM
Weirauch et al.(2014)
pTH5647 		0.631 0.631
E2F
M01959_2.00 		Dictyostelium discoideum
NNGSGCGCSHN
NDSGCGCSCNN		 PBM
Weirauch et al.(2014)
pTH5403 		0.554 0.554
E2F6
M08107_2.00 		Homo sapiens
DGGMGGGARVN
NBYTCCCKCCH		 ChIP-seq
Mathelier et al.(2014)
MA0471.1 		0.554 0.554
E2F6
M07939_2.00 		Homo sapiens
NDSGCGGGARV
BYTCCCGCSHN		 ChIP-seq
Gerstein et al.(2012)
HeLa-S3_E2F6_UCD 		0.554 0.554
E2F6
M07940_2.00 		Homo sapiens
NDVGCGGGARV
BYTCCCGCBHN		 ChIP-seq
Gerstein et al.(2012)
K562b_E2F6_UCD 		0.554 0.554
E2F6
M07941_2.00 		Homo sapiens
NDSGCGGGARV
BYTCCCGCSHN		 ChIP-seq
Gerstein et al.(2012)
K562_E2F6_HudsonAlpha 		0.554 0.554
E2F6
M09034_2.00 		Homo sapiens
NRGGMGGGARRNN
NNYYTCCCKCCYN		 Misc
Kulakovskiy et al.(2013)
E2F6_HUMAN.H11MO.0.A 		0.554 0.554
E2f6
M09043_2.00 		Mus musculus
NDGGCGGGARVV
BBYTCCCGCCHN		 Misc
Kulakovskiy et al.(2013)
E2F6_MOUSE.H11MO.0.A 		0.554 0.554
E2F6
M09523_2.00 		Homo sapiens
VGCGGGARNN
NNYTCCCGCB		 Misc
Heinz et al.(2010)
Hela-E2F6_GSE31477 		0.554 0.554
E2F6
M10456_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F6_01 		0.554 0.554
estExt_gwp_GeneWisePlus.C_Chr_02.00010270
M01969_2.00 		Ostreococcus tauri
HRVGCGCCNN
NNGGCGCBYD		 PBM
Weirauch et al.(2014)
pTH5701 		0.538 0.538
efl-2
M01966_2.00 		Caenorhabditis elegans
NDBGCGSBNN
NNVSCGCVHN		 PBM
Weirauch et al.(2014)
pTH5916 		0.462 0.462
efl-2
M00662_2.00 		Caenorhabditis elegans
NSGCGSNNDN
NHNNSCGCSN		 PBM
Narasimhan et al.(2015)
pTH9173 		0.462 0.462
TVAG_062990
M01967_2.00 		Trichomonas vaginalis
NNSGCGSBNN
NNVSCGCSNN		 PBM
Weirauch et al.(2014)
pTH5727 		0.446 0.446
For this family, TFs with SR scores > 0.429 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSCINP00000030840 E2F 164 228

Links

Other E2F family TFs
Other Ciona intestinalis TFs

1025 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CaO19.1499 Candida albicans CaO19.1499 N 0.000
CaO19.9075 Candida albicans CaO19.9075 N 0.000
CD36_16710 Candida dubliniensis CD36_16710 N 0.000
PGUG_03166 Candida guilliermondii PGUG_03166 N 0.000
PGUG_03167 Candida guilliermondii PGUG_03167 N 0.000
CLUG_02329 Candida lusitaniae CLUG_02329 N 0.000
G210_2898 Candida maltosa G210_2898 N 0.000
CORT_0A09500 Candida orthopsilosis CORT_0A09500 N 0.000
CPAG_03070 Candida parapsilosis CPAG_03070 N 0.000
CANTEDRAFT_100135 Candida tenuis CANTEDRAFT_100135 N 0.000
CTRG_01280 Candida tropicalis CTRG_01280 N 0.000
PV07_10612 Cladophialophora immunda PV07_10612 N 0.000
CLUG_02329 Clavispora lusitaniae CLUG_02329 N 0.000
DEHA2B04070g Debaryomyces hansenii DEHA2B04070g N 0.000
DEHA2B04048g Debaryomyces hansenii DEHA2B04048g N 0.000
LELG_00946 Lodderomyces elongisporus LELG_00946 N 0.000
PGUG_03166 Meyerozyma guilliermondii PGUG_03166 N 0.000
PGUG_03167 Meyerozyma guilliermondii PGUG_03167 N 0.000
GNLVRS01_PISO0A07920g Millerozyma farinosa GNLVRS01_PISO0A07920g N 0.000
GNLVRS01_PISO0B07987g Millerozyma farinosa GNLVRS01_PISO0B07987g N 0.000
e_gww1.3.1.128.1 Pichia stipitis e_gww1.3.1.128.1 N 0.000
PICST_57681 Scheffersomyces stipitis PICST_57681 N 0.000
M407DRAFT_127560 Tulasnella calospora M407DRAFT_127560 I 0.000
M407DRAFT_247126 Tulasnella calospora M407DRAFT_247126 I 0.000