E2F4 (Gallus gallus)
E2F

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF02319 (E2F_TDP) IPR003316 ENSGALG00000001722 T172634_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
E2F4
M02961_2.00 		Homo sapiens
AATGGCGCCAAA
TTTGGCGCCATT		 SELEX
Jolma et al.(2013)
E2F4_1 		1.000 1.000
E2F4
M02962_2.00 		Homo sapiens
TTTGGCGCCAAA
TTTGGCGCCAAA		 SELEX
Jolma et al.(2013)
E2F4_2 		1.000 1.000
E2F4
M04707_2.00 		Homo sapiens
NWWKGGCGCCAAAW
WTTTGGCGCCMWWN		 SELEX
Yin et al.(2017)
E2F4_eDBD_HT-SELEX 		1.000 1.000
E2F4
M08109_2.00 		Homo sapiens
NSGCGGGARVN
NBYTCCCGCSN		 ChIP-seq
Mathelier et al.(2014)
MA0470.1 		1.000 1.000
E2F4
M07942_2.00 		Homo sapiens
SGCGSGARDNNBNVN
NBNVNNHYTCSCGCS		 ChIP-seq
Gerstein et al.(2012)
HeLa-S3_E2F4_UCD 		1.000 1.000
E2F4
M07943_2.00 		Homo sapiens
SGCGGGARDNNBVVN
NBBVNNHYTCCCGCS		 ChIP-seq
Gerstein et al.(2012)
K562b_E2F4_UCD 		1.000 1.000
E2F4
M09036_2.00 		Homo sapiens
VDRGGCGGGRVND
HNBYCCCGCCYHB		 Misc
Kulakovskiy et al.(2013)
E2F4_HUMAN.H11MO.0.A 		1.000 1.000
E2f4
M09037_2.00 		Mus musculus
NRDDGGCGGGRMNN
NNKYCCCGCCHHYN		 Misc
Kulakovskiy et al.(2013)
E2F4_MOUSE.H11MO.0.A 		1.000 1.000
E2F4
M09524_2.00 		Homo sapiens
VGCGSGAADH
DHTTCSCGCB		 Misc
Heinz et al.(2010)
K562-E2F4_GSE31477 		1.000 1.000
E2F4
M10457_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F4_05 		1.000 1.000
E2F4
M10458_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F4_Q3 		1.000 1.000
E2F4
M10459_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F4_Q6 		1.000 1.000
E2f5
M09042_2.00 		Mus musculus
NGCGCSAAAN
NTTTSGCGCN		 Misc
Kulakovskiy et al.(2013)
E2F5_MOUSE.H11MO.0.B 		0.954 0.954
e_gw1.38.2.1
M01968_2.00 		Physcomitrella patens
NSGCGCBHHN
NDDVGCGCSN		 PBM
Weirauch et al.(2014)
pTH5707 		0.754 0.754
estExt_gwp_gw1.C_220046
M01225_2.00 		Physcomitrella patens
VGCGCBHHNN
NNDDVGCGCB		 PBM
Lambert et al.(2019)
pTH9809 		0.754 0.754
ENSACAG00000013716
M01960_2.00 		Anolis carolinensis
HNVGCGCBND
HNVGCGCBND		 PBM
Weirauch et al.(2014)
pTH9221 		0.738 0.738
E2F2
M01963_2.00 		Tupaia belangeri
WDVGCGCBHW
WDVGCGCBHW		 PBM
Weirauch et al.(2014)
pTH9291 		0.738 0.738
E2f2
M00154_2.00 		Mus musculus
NDNNGCGSBN
NVSCGCNNHN		 PBM
Badis et al.(2009)
E2F2_1022 		0.723 0.723
E2FA
M06871_2.00 		Arabidopsis thaliana
NDDDGGCGCCAWWW
WWWTGGCGCCHHHN		 Dap-seq
OMalley et al.(2016)
E2FA_col_a 		0.723 0.723
E2FA
M06872_2.00 		Arabidopsis thaliana
DDWDGGCGCCAWAD
HTWTGGCGCCHWHH		 Dap-seq
OMalley et al.(2016)
E2FA_colamp_a 		0.723 0.723
E2FC
M06870_2.00 		Arabidopsis thaliana
AWDDDGGCGCCAAAR
YTTTGGCGCCHHHWT		 Dap-seq
OMalley et al.(2016)
E2FC_col_a 		0.723 0.723
E2FA
M08106_2.00 		Arabidopsis thaliana
NVGCGCCAHN
NDTGGCGCBN		 ChIP-seq
Mathelier et al.(2014)
MA1414.1 		0.723 0.723
E2f2
M09039_2.00 		Mus musculus
GGCGCGMAWC
GWTKCGCGCC		 Misc
Kulakovskiy et al.(2013)
E2F2_MOUSE.H11MO.0.B 		0.723 0.723
E2F2
M01961_2.00 		Homo sapiens
DNSGCGCSNH
DNSGCGCSNH		 PBM
Weirauch et al.(2014)
pTH9195 		0.708 0.708
ENSOANG00000014967
M01962_2.00 		Ornithorhynchus anatinus
NDSGCGCSHN
NDSGCGCSHN		 PBM
Weirauch et al.(2014)
pTH9382 		0.708 0.708
E2F3
M01964_2.00 		Taeniopygia guttata
NNSGCGCGMN
NKCGCGCSNN		 PBM
Weirauch et al.(2014)
pTH9288 		0.708 0.708
E2F2
M02949_2.00 		Homo sapiens
AAAAATGGCGCCAAAAWD
HWTTTTGGCGCCATTTTT		 SELEX
Jolma et al.(2013)
E2F2_1 		0.708 0.708
E2F2
M02950_2.00 		Homo sapiens
VDTTTTGGCGCCAAAAHN
NDTTTTGGCGCCAAAAHB		 SELEX
Jolma et al.(2013)
E2F2_2 		0.708 0.708
E2F2
M02951_2.00 		Homo sapiens
AAAWWGGCGCCAWTTT
AAAWTGGCGCCWWTTT		 SELEX
Jolma et al.(2013)
E2F2_3 		0.708 0.708
E2F2
M04696_2.00 		Homo sapiens
GCGCGCGCSYW
WRSGCGCGCGC		 SELEX
Yin et al.(2017)
E2F2_eDBD_HT-SELEX_1 		0.708 0.708
E2F2
M04697_2.00 		Homo sapiens
NDWWDGGCGCCWWHWN
NWDWWGGCGCCHWWHN		 SELEX
Yin et al.(2017)
E2F2_eDBD_HT-SELEX_2 		0.708 0.708
E2F2
M09029_2.00 		Homo sapiens
GGCGCGMAWC
GWTKCGCGCC		 Misc
Kulakovskiy et al.(2013)
E2F2_HUMAN.H11MO.0.B 		0.708 0.708
E2F2
M04698_2.00 		Homo sapiens
SGBGSGCGCGS
SCGCGCSCVCS		 SELEX
Yin et al.(2017)
E2F2_eDBD_Methyl-HT-SELEX_1 		0.708 0.708
E2F2
M04699_2.00 		Homo sapiens
DWWWDGGCGCCAAAWH
DWTTTGGCGCCHWWWH		 SELEX
Yin et al.(2017)
E2F2_eDBD_Methyl-HT-SELEX_2 		0.708 0.708
E2f3
M00153_2.00 		Mus musculus
NNNNGCGSNN
NNSCGCNNNN		 PBM
Badis et al.(2009)
E2F3_3752 		0.692 0.692
E2F3
M02956_2.00 		Homo sapiens
RAAAAKGGCGCCAAAANN
NNTTTTGGCGCCMTTTTY		 SELEX
Jolma et al.(2013)
E2F3_1 		0.692 0.692
E2F3
M02957_2.00 		Homo sapiens
DAAAADGGCGCCMWWTTY
RAAWWKGGCGCCHTTTTH		 SELEX
Jolma et al.(2013)
E2F3_2 		0.692 0.692
E2F3
M02958_2.00 		Homo sapiens
NDTTTTGGCGCCAAAABH
DVTTTTGGCGCCAAAAHN		 SELEX
Jolma et al.(2013)
E2F3_3 		0.692 0.692
E2F3
M04701_2.00 		Homo sapiens
DWTTTGGCGCCAAAWH
DWTTTGGCGCCAAAWH		 SELEX
Yin et al.(2017)
E2F3_eDBD_HT-SELEX 		0.692 0.692
E2F3
M09031_2.00 		Homo sapiens
NDGGCGGGAAR
YTTCCCGCCHN		 Misc
Kulakovskiy et al.(2013)
E2F3_HUMAN.H11MO.0.A 		0.692 0.692
E2f3
M09038_2.00 		Mus musculus
DSGCGGGARV
BYTCCCGCSH		 Misc
Kulakovskiy et al.(2013)
E2F3_MOUSE.H11MO.0.A 		0.692 0.692
E2F3
M10454_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F1_Q6_01 		0.692 0.692
E2F3
M10455_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F3_Q6 		0.692 0.692
E2F3
M04702_2.00 		Homo sapiens
DTTTTGGCGCCAAAAH
DTTTTGGCGCCAAAAH		 SELEX
Yin et al.(2017)
E2F3_eDBD_Methyl-HT-SELEX 		0.692 0.692
E2f
M08196_2.00 		Drosophila melanogaster
AAWWBSSCGSCAA
TTGSCGSSVWWTT		 ChIP-seq
Contrino et al.(2012)
Mf10 		0.677 0.677
E2F1
M02952_2.00 		Homo sapiens
WWDGGCGCCAAW
WTTGGCGCCHWW		 SELEX
Jolma et al.(2013)
E2F1_1 		0.662 0.662
E2F1
M02953_2.00 		Homo sapiens
WWKGGCGCCWWW
WWWGGCGCCMWW		 SELEX
Jolma et al.(2013)
E2F1_2 		0.662 0.662
E2F1
M02954_2.00 		Homo sapiens
WWWKGGCGCCMWWW
WWWKGGCGCCMWWW		 SELEX
Jolma et al.(2013)
E2F1_3 		0.662 0.662
E2F1
M02955_2.00 		Homo sapiens
AAWKGGCGCCAWTW
WAWTGGCGCCMWTT		 SELEX
Jolma et al.(2013)
E2F1_4 		0.662 0.662
E2F1
M04700_2.00 		Homo sapiens
NWWWDGGCGCCAAAWH
DWTTTGGCGCCHWWWN		 SELEX
Yin et al.(2017)
E2F1_FL_HT-SELEX 		0.662 0.662
efl-1
M08110_2.00 		Caenorhabditis elegans
HNHNSGCGSSAAWWN
NWWTTSSCGCSNDND		 ChIP-seq
Mathelier et al.(2014)
MA0541.1 		0.662 0.662
E2F1
M07938_2.00 		Homo sapiens
VRRVNRVGCGSGMDS
SHKCSCGCBYNBYYB		 ChIP-seq
Gerstein et al.(2012)
HeLa-S3_E2F1_UCD 		0.662 0.662
efl-1
M08197_2.00 		Caenorhabditis elegans
BGCGSSAAWW
WWTTSSCGCV		 ChIP-seq
Contrino et al.(2012)
Mw140 		0.662 0.662
E2F1
M09030_2.00 		Homo sapiens
NVNDGGCGGGARVN
NBYTCCCGCCHNBN		 Misc
Kulakovskiy et al.(2013)
E2F1_HUMAN.H11MO.0.A 		0.662 0.662
E2f1
M09041_2.00 		Mus musculus
NDDGGCGGGRVN
NBYCCCGCCHHN		 Misc
Kulakovskiy et al.(2013)
E2F1_MOUSE.H11MO.0.A 		0.662 0.662
efl-1
M09526_2.00 		Caenorhabditis elegans
WGCAARYGCGCTCYA
TRGAGCGCRYTTGCW		 Misc
Heinz et al.(2010)
cElegans-L1-EFL1_modEncode 		0.662 0.662
E2F1
M09521_2.00 		Homo sapiens
NNGGCGGGAA
TTCCCGCCNN		 Misc
Heinz et al.(2010)
Hela-E2F1_GSE22478 		0.662 0.662
E2F1
M10444_2.00 		Homo sapiens
THVGCGCGAAAAHKR
YMDTTTTCGCGCBDA		 Transfac
Matys et al.(2006)
V$E2F_01 		0.662 0.662
E2F1
M10445_2.00 		Homo sapiens
BHKSGCGCSAAA
TTTSGCGCSMDV		 Transfac
Matys et al.(2006)
V$E2F_03 		0.662 0.662
E2F1
M10446_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F1_01 		0.662 0.662
E2F1
M10447_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F1_02 		0.662 0.662
E2F1
M10448_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F1_Q3_01 		0.662 0.662
E2F1
M10449_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F1_Q3 		0.662 0.662
E2F1
M10450_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F1_Q4_01 		0.662 0.662
E2F1
M10451_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F1_Q4_02 		0.662 0.662
E2F1
M10452_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F1_Q4 		0.662 0.662
E2F1
M10453_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F1_Q6 		0.662 0.662
GSPATT00020286001
M01965_2.00 		Paramecium tetraurelia
NNSGCGSBN
NVSCGCSNN		 PBM
Weirauch et al.(2014)
pTH5647 		0.600 0.600
E2F
M01959_2.00 		Dictyostelium discoideum
NNGSGCGCSHN
NDSGCGCSCNN		 PBM
Weirauch et al.(2014)
pTH5403 		0.569 0.569
E2F6
M08107_2.00 		Homo sapiens
DGGMGGGARVN
NBYTCCCKCCH		 ChIP-seq
Mathelier et al.(2014)
MA0471.1 		0.569 0.569
E2F6
M07939_2.00 		Homo sapiens
NDSGCGGGARV
BYTCCCGCSHN		 ChIP-seq
Gerstein et al.(2012)
HeLa-S3_E2F6_UCD 		0.569 0.569
E2F6
M07940_2.00 		Homo sapiens
NDVGCGGGARV
BYTCCCGCBHN		 ChIP-seq
Gerstein et al.(2012)
K562b_E2F6_UCD 		0.569 0.569
E2F6
M07941_2.00 		Homo sapiens
NDSGCGGGARV
BYTCCCGCSHN		 ChIP-seq
Gerstein et al.(2012)
K562_E2F6_HudsonAlpha 		0.569 0.569
E2F6
M09034_2.00 		Homo sapiens
NRGGMGGGARRNN
NNYYTCCCKCCYN		 Misc
Kulakovskiy et al.(2013)
E2F6_HUMAN.H11MO.0.A 		0.569 0.569
E2f6
M09043_2.00 		Mus musculus
NDGGCGGGARVV
BBYTCCCGCCHN		 Misc
Kulakovskiy et al.(2013)
E2F6_MOUSE.H11MO.0.A 		0.569 0.569
E2F6
M09523_2.00 		Homo sapiens
VGCGGGARNN
NNYTCCCGCB		 Misc
Heinz et al.(2010)
Hela-E2F6_GSE31477 		0.569 0.569
E2F6
M10456_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F6_01 		0.569 0.569
estExt_gwp_GeneWisePlus.C_Chr_02.00010270
M01969_2.00 		Ostreococcus tauri
HRVGCGCCNN
NNGGCGCBYD		 PBM
Weirauch et al.(2014)
pTH5701 		0.538 0.538
efl-2
M01966_2.00 		Caenorhabditis elegans
NDBGCGSBNN
NNVSCGCVHN		 PBM
Weirauch et al.(2014)
pTH5916 		0.492 0.492
efl-2
M00662_2.00 		Caenorhabditis elegans
NSGCGSNNDN
NHNNSCGCSN		 PBM
Narasimhan et al.(2015)
pTH9173 		0.492 0.492
For this family, TFs with SR scores > 0.429 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSGALP00000002638 E2F 32 97

Links

Other E2F family TFs
Other Gallus gallus TFs

1059 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
AAEL003602 Aedes aegypti AAEL003602 N 0.000
Alligator_sinensis_CCG009248.1 Alligator sinensis Alligator_sinensis_CCG009248.1 N 0.000
PRDM8 Anolis carolinensis ENSACAG00000010106 N 0.000
AALB005765 Anopheles albimanus AALB005765 N 0.000
AARA007771 Anopheles arabiensis AARA007771 N 0.000
AATE006171 Anopheles atroparvus AATE006171 N 0.000
ACHR001790 Anopheles christyi ACHR001790 N 0.000
ACUA006984 Anopheles culicifacies ACUA006984 N 0.000
ADIR008055 Anopheles dirus ADIR008055 N 0.000
AEPI001699 Anopheles epiroticus AEPI001699 N 0.000
AFAF012484 Anopheles farauti AFAF012484 N 0.000
AFUN008026 Anopheles funestus AFUN008026 N 0.000
AGAP007109 Anopheles gambiae AGAP007109 N 0.000
AMAM024265 Anopheles maculatus AMAM024265 N 0.000
AMEC009079 Anopheles melas AMEC009079 N 0.000
AMEC019433 Anopheles melas AMEC019433 N 0.000
AMEM014597 Anopheles merus AMEM014597 N 0.000
AMIN011248 Anopheles minimus AMIN011248 N 0.000
AQUA002036 Anopheles quadriannulatus AQUA002036 N 0.000
ASIS021384 Anopheles sinensis ASIS021384 N 0.000
ASTEI06883 Anopheles stephensi ASTEI06883 N 0.000
ENSAMXG00000020060 Astyanax mexicanus ENSAMXG00000020060 N 0.000
BGIBMGA012741 Bombyx mori BGIBMGA012741 N 0.000
fgenesh2_pg.scaffold_282000018 Branchiostoma floridae fgenesh2_pg.scaffold_282000018 N 0.000
PRDM8 Callithrix jacchus ENSCJAG00000015064 N 0.000
PRDM8 Canis familiaris ENSCAFG00000008881 N 0.000
CapteG221467 Capitella teleta CapteG221467 N 0.000
PRDM8 Cavia porcellus ENSCPOG00000019738 N 0.000
ENSCSAG00000004478 Chlorocebus sabaeus ENSCSAG00000004478 N 0.000
CpipJ_CPIJ004963 Culex pipiens CpipJ_CPIJ004963 N 0.000
CPIJ004963 Culex quinquefasciatus CPIJ004963 N 0.000
KGM_11907 Danaus plexippus KGM_11907 N 0.000
prdm8b Danio rerio ENSDARG00000054683 N 0.000
PRDM8 Dasypus novemcinctus ENSDNOG00000011667 N 0.000
ENSECAG00000017767 Equus caballus ENSECAG00000017767 N 0.000
ENSFCAG00000026794 Felis catus ENSFCAG00000026794 N 0.000
ENSGMOG00000016370 Gadus morhua ENSGMOG00000016370 N 0.000
ENSGALG00000026560 Gallus gallus ENSGALG00000026560 N 0.000
PRDM8 Gorilla gorilla ENSGGOG00000007501 N 0.000
HMEL017852 Heliconius melpomene HMEL017852 N 0.000
PRDM8 Homo sapiens ENSG00000152784 N 0.000
ENSSTOG00000015688 Ictidomys tridecemlineatus ENSSTOG00000015688 N 0.000
ISCW009928 Ixodes scapularis ISCW009928 N 0.000
ENSLACG00000001866 Latimeria chalumnae ENSLACG00000001866 N 0.000
ENSLOCG00000007226 Lepisosteus oculatus ENSLOCG00000007226 N 0.000
LDEC001191 Leptinotarsa decemlineata LDEC001191 N 0.000
LotgiG69958 Lottia gigantea LotgiG69958 N 0.000
LCUP008185 Lucilia cuprina LCUP008185 N 0.000
ENSP00000406998 Macaca fascicularis ENSP00000406998 N 0.000
PRDM8 Macaca mulatta ENSMMUG00000003338 N 0.000
ENSMEUG00000015872 Macropus eugenii ENSMEUG00000015872 N 0.000
MCINX010301 Melitaea cinxia MCINX010301 N 0.000
PRDM8 Monodelphis domestica ENSMODG00000020789 N 0.000
MDOA007546 Musca domestica MDOA007546 N 0.000
ENSMPUG00000006558 Mustela putorius furo ENSMPUG00000006558 N 0.000
Prdm8 Mus musculus ENSMUSG00000035456 N 0.000
PRDM8 Myotis lucifugus ENSMLUG00000030190 N 0.000
ENSNLEG00000008504 Nomascus leucogenys ENSNLEG00000008504 N 0.000
Ocbimv22006527m.g Octopus bimaculoides Ocbimv22006527m.g N 0.000
Ogr08710 Ophisaurus gracilis Ogr08710 N 0.000
ENSONIG00000014038 Oreochromis niloticus ENSONIG00000014038 N 0.000
prdm8b Oryzias latipes ENSORLG00000017786 N 0.000
ENSOGAG00000026262 Otolemur garnettii ENSOGAG00000026262 N 0.000
ENSOARG00000018972 Ovis aries ENSOARG00000018972 N 0.000
ENSPANG00000024349 Papio anubis ENSPANG00000024349 N 0.000
PHUM271650 Pediculus humanus PHUM271650 N 0.000
ENSPMAG00000005756 Petromyzon marinus ENSPMAG00000005756 N 0.000
PPAI006396 Phlebotomus papatasi PPAI006396 N 0.000
ENSPFOG00000011716 Poecilia formosa ENSPFOG00000011716 N 0.000
Pvit_15291 Pogona vitticeps Pvit_15291 N 0.000
PRDM8 Procavia capensis ENSPCAG00000001081 N 0.000
Prdm8 Rattus norvegicus ENSRNOG00000002004 N 0.000
Sakowv30017448m.g Saccoglossus kowalevskii Sakowv30017448m.g N 0.000
ENSSHAG00000018147 Sarcophilus harrisii ENSSHAG00000018147 N 0.000
SMU15028407 Schmidtea mediterranea SMU15028407 N 0.000
PRDM8 Sorex araneus ENSSARG00000009823 N 0.000
SMAR006435 Strigamia maritima SMAR006435 N 0.000
prdm8b Takifugu rubripes ENSTRUG00000001003 N 0.000
tetur11g03890 Tetranychus urticae tetur11g03890 N 0.000
prdm8b Tetraodon nigroviridis ENSTNIG00000016712 N 0.000
TC013073 Tribolium castaneum TC013073 N 0.000
PRDM8 Tupaia belangeri ENSTBEG00000006138 N 0.000
prdm8 Xenopus tropicalis XB-GENE-984391 N 0.000
ENSXMAG00000009993 Xiphophorus maculatus ENSXMAG00000009993 N 0.000
L798_05037 Zootermopsis nevadensis L798_05037 N 0.000