CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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elt-2
(
Caenorhabditis elegans
)
GATA
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00320 (GATA)
IPR000679
WBGene00001250
T195702_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and enzyme inhibitor activity. Involved in several processes, including defense response to other organism; endoderm development; and nematode larval development. Located in nucleus. Is expressed in several structures, including Ea; Eal; anal region; head neurons; and intestine. Human ortholog(s) of this gene implicated in adenocarcinoma (multiple); congenital heart disease (multiple); and pancreatic hypoplasia-diabetes-congenital heart disease syndrome. Orthologous to human GATA4 (GATA binding protein 4); GATA5 (GATA binding protein 5); and GATA6 (GATA binding protein 6). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
No direct experiments
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
GATAe
M03761_2.00
Drosophila melanogaster
VHGATAAS
STTATCDB
SELEX
Nitta et al.(2015)
GATAe_1
0.842
0.686
GATAe
M03762_2.00
Drosophila melanogaster
HGATAACNNNGTTATCD
HGATAACNNNGTTATCD
SELEX
Nitta et al.(2015)
GATAe_2
0.842
0.686
GATAe
M03763_2.00
Drosophila melanogaster
HGATAAGNNNCTTATCD
HGATAAGNNNCTTATCD
SELEX
Nitta et al.(2015)
GATAe_3
0.842
0.686
GATAe
M06208_2.00
Drosophila melanogaster
WGATAAG
CTTATCW
B1H
Zhu et al.(2011)
GATAe_SANGER_5_FBgn0038391
0.842
0.686
nit-2
M02017_2.00
Neurospora crassa
NNGATHNN
NNDATCNN
PBM
Weirauch et al.(2014)
pTH8624
0.817
0.571
nit-2
M10601_2.00
Neurospora crassa
DHGATA
TATCDH
Transfac
Matys et al.(2006)
F$NIT2_01
0.817
0.571
For this family, TFs with SR scores >
0.802
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
C33D3.1
GATA
237
271
CSNCNGTNTTLWRRNAEGDPVCNACGLYFKLHHIP
Links
Other
GATA
family TFs
Other
Caenorhabditis elegans
TFs
438 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy