CIS-BP Database: Catalog of Inferred Sequence Binding Preferences

TF Information

ENSAMEG00000008199 *(Ailuropoda melanoleuca)* Homeodomain
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF00046 (Homeobox)	IPR001356	ENSAMEG00000008199	T206906_2.00	Ensembl (2018-Dec-8)	Link out
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
Meis3 M00488_2.00	Mus musculus	NTGACANNN	NNNTGTCAN	PBM Berger et al.(2008) Mrg2_2302	0.867	1.000
MEIS3 M03093_2.00	Homo sapiens	DTGACANN	NNTGTCAH	SELEX Jolma et al.(2013) MEIS3_1	0.858	0.946
MEIS3 M03094_2.00	Homo sapiens	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) MEIS3_2	0.858	0.946
Meis3 M03279_2.00	Mus musculus	NTGACAN	NTGTCAN	SELEX Jolma et al.(2013) Meis3_1	0.867	1.000
Meis3 M03280_2.00	Mus musculus	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) Meis3_2	0.867	1.000
MEIS3 M04951_2.00	Homo sapiens	TGWCABVTGWCA	TGWCABVTGWCA	SELEX Yin et al.(2017) MEIS3_eDBD_HT-SELEX	0.858	0.946
Meis1 M00407_2.00	Mus musculus	NTGACADNN	NNHTGTCAN	PBM Berger et al.(2008) Meis1_2335	0.835	0.982
MEIS3 M04952_2.00	Homo sapiens	YGWCABVTGWCR	YGWCABVTGWCR	SELEX Yin et al.(2017) MEIS3_eDBD_Methyl-HT-SELEX	0.858	0.946
Meis2 M00437_2.00	Mus musculus	NTGACANNN	NNNTGTCAN	PBM Berger et al.(2008) Mrg1_2246	0.835	0.982
Q5EVH4_OIKDI M02227_2.00	Oikopleura dioica	NTGACAKN	NMTGTCAN	PBM Weirauch et al.(2014) pTH6041	0.759	0.757
MEIS1 M03165_2.00	Homo sapiens	NTGACAN	NTGTCAN	SELEX Jolma et al.(2013) MEIS1_1	0.835	0.982
KNAT7 M01064_2.00	Arabidopsis thaliana	TGACRKST	ASMYGTCA	PBM Sullivan et al.(2014) pTH9798	0.659	0.486
MEIS2 M03147_2.00	Homo sapiens	WTGACAGSTGTCAM	KTGACASCTGTCAW	SELEX Jolma et al.(2013) MEIS2_1	0.835	0.982
KNAT4 M01238_2.00	Arabidopsis thaliana	NNGACNNNN	NNNNGTCNN	PBM Lambert et al.(2019) pTH9968	0.655	0.541
MEIS2 M03148_2.00	Homo sapiens	DTGACAGS	SCTGTCAH	SELEX Jolma et al.(2013) MEIS2_2	0.835	0.982
KNAT3 M02051_2.00	Arabidopsis thaliana	NNNGACVBNN	NNVBGTCNNN	PBM Weirauch et al.(2014) pTH7600	0.655	0.541
HOS66 M02156_2.00	Oryza sativa	NNNNDHNN	NNDHNNNN	PBM Weirauch et al.(2014) pTH8332	0.620	0.486
Meis2 M03261_2.00	Mus musculus	NTGACAN	NTGTCAN	SELEX Jolma et al.(2013) Meis2_1	0.835	0.982
Meis2 M03262_2.00	Mus musculus	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) Meis2_2	0.835	0.982
MEIS2 M02740_2.00	Homo sapiens	TGACASSTGTC	GACASSTGTCA	SELEX Jolma et al.(2010) MEIS2_dimer	0.835	0.982
MEIS2 M02741_2.00	Homo sapiens	GGACAKNT	ANMTGTCC	SELEX Jolma et al.(2010) MEIS2_monomer	0.835	0.982
MEIS2 M05138_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) MEIS2_eDBD_HT-SELEX	0.835	0.982
MEIS2 M05140_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) MEIS2_FL_HT-SELEX	0.835	0.982
MEIS1 M09148_2.00	Homo sapiens	NTGATTDATDDB	VHHATHAATCAN	Misc Kulakovskiy et al.(2013) MEIS1_HUMAN.H11MO.0.A	0.835	0.982
MEIS2 M09143_2.00	Homo sapiens	HTGACAGBTKTBM	KVAMAVCTGTCAD	Misc Kulakovskiy et al.(2013) MEIS2_HUMAN.H11MO.0.B	0.835	0.982
Meis1 M09178_2.00	Mus musculus	NTGATTDATDDB	VHHATHAATCAN	Misc Kulakovskiy et al.(2013) MEIS1_MOUSE.H11MO.0.A	0.835	0.982
Meis2 M09189_2.00	Mus musculus	HTGACAGBTKTBM	KVAMAVCTGTCAD	Misc Kulakovskiy et al.(2013) MEIS2_MOUSE.H11MO.0.B	0.835	0.982
Meis1 M09568_2.00	Mus musculus	VBTGWCASNN	NNSTGWCAVB	Misc Heinz et al.(2010) MastCells-Meis1_GSE48085	0.835	0.982
MEIS1 M10709_2.00	Homo sapiens	NHNTGACAGNDN	NHNCTGTCANDN	Transfac Matys et al.(2006) V$MEIS1_01	0.835	0.982
MEIS1 M10710_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$MEIS1_06	0.835	0.982
MEIS2 M05139_2.00	Homo sapiens	YGACASSYGHCR	YGDCRSSTGTCR	SELEX Yin et al.(2017) MEIS2_eDBD_Methyl-HT-SELEX	0.835	0.982
MEIS2 M05141_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) MEIS2_FL_Methyl-HT-SELEX	0.835	0.982
hth M06490_2.00	Drosophila melanogaster	TGACAK	MTGTCA	B1H Mathelier et al.(2014) MA0227.1	0.835	0.945
hth M06252_2.00	Drosophila melanogaster	TGTCA	TGACA	B1H Zhu et al.(2011) Hth_Cell_FBgn0001235	0.835	0.945
hth M06253_2.00	Drosophila melanogaster	NNTGACAD	HTGTCANN	B1H Zhu et al.(2011) hth_SOLEXA_2_FBgn0001235	0.835	0.945
hth M06254_2.00	Drosophila melanogaster	NTGACA	TGTCAN	B1H Zhu et al.(2011) Hth_SOLEXA_FBgn0001235	0.835	0.945
unc-62 M02185_2.00	Caenorhabditis elegans	NHDAHANNN	NNNTDTHDN	PBM Weirauch et al.(2014) pTH5781	0.778	0.818
Pknox1 M00399_2.00	Mus musculus	HGACRNNN	NNNYGTCD	PBM Berger et al.(2008) Pknox1_2364	0.751	0.727
Pknox2 M00468_2.00	Mus musculus	NNNGACRNNN	NNNYGTCNNN	PBM Berger et al.(2008) Pknox2_3077	0.751	0.727
PKNOX1 M03178_2.00	Homo sapiens	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) PKNOX1_1	0.751	0.727
PKNOX2 M03195_2.00	Homo sapiens	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) PKNOX2_1	0.751	0.727
Pknox2 M03270_2.00	Mus musculus	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) Pknox2_1	0.751	0.727
PKNOX1 M05206_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) PKNOX1_eDBD_HT-SELEX	0.751	0.727
PKNOX1 M05208_2.00	Homo sapiens	TGACAGCTGTCA	TGACAGCTGTCA	SELEX Yin et al.(2017) PKNOX1_FL_HT-SELEX	0.751	0.727
PKNOX2 M05246_2.00	Homo sapiens	TGACABVTGTCA	TGACABVTGTCA	SELEX Yin et al.(2017) PKNOX2_eDBD_HT-SELEX	0.751	0.727
PKNOX1 M09150_2.00	Homo sapiens	TGABTGRCRGV	BCYGYCAVTCA	Misc Kulakovskiy et al.(2013) PKNX1_HUMAN.H11MO.0.B	0.751	0.727
Pknox1 M09175_2.00	Mus musculus	TGABTGRCRGV	BCYGYCAVTCA	Misc Kulakovskiy et al.(2013) PKNX1_MOUSE.H11MO.0.A	0.751	0.727
PKNOX1 M10712_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PREP1_Q3	0.751	0.727
PKNOX1 M05207_2.00	Homo sapiens	YGWCASSTGWCR	YGWCASSTGWCR	SELEX Yin et al.(2017) PKNOX1_eDBD_Methyl-HT-SELEX	0.751	0.727
PKNOX1 M05209_2.00	Homo sapiens	TGACABVTGTCA	TGACABVTGTCA	SELEX Yin et al.(2017) PKNOX1_FL_Methyl-HT-SELEX	0.751	0.727
PKNOX2 M05247_2.00	Homo sapiens	TGACASSTGTCA	TGACASSTGTCA	SELEX Yin et al.(2017) PKNOX2_eDBD_Methyl-HT-SELEX	0.751	0.727
achi M03860_2.00	Drosophila melanogaster	TGACAD	HTGTCA	SELEX Nitta et al.(2015) achi_1	0.657	0.527
achi M03861_2.00	Drosophila melanogaster	TGACAGMTGTCA	TGACAKCTGTCA	SELEX Nitta et al.(2015) achi_2	0.657	0.527
achi M03862_2.00	Drosophila melanogaster	TGACAGNNNNNNYGTCA	TGACRNNNNNNCTGTCA	SELEX Nitta et al.(2015) achi_3	0.657	0.527
vis M03859_2.00	Drosophila melanogaster	TGACAS	STGTCA	SELEX Nitta et al.(2015) vis_1	0.657	0.527
vis M06534_2.00	Drosophila melanogaster	TGACAB	BTGTCA	B1H Mathelier et al.(2014) MA0252.1	0.657	0.527
achi M06535_2.00	Drosophila melanogaster	TGACAG	CTGTCA	B1H Mathelier et al.(2014) MA0207.1	0.657	0.527
achi M06345_2.00	Drosophila melanogaster	TGTCADW	WHTGACA	B1H Zhu et al.(2011) Achi_Cell_FBgn0033749	0.657	0.527
achi M06346_2.00	Drosophila melanogaster	HTGACA	TGTCAD	B1H Zhu et al.(2011) Achi_SOLEXA_FBgn0033749	0.657	0.527
vis M06343_2.00	Drosophila melanogaster	TGTCA	TGACA	B1H Zhu et al.(2011) Vis_Cell_FBgn0033748	0.657	0.527
vis M06344_2.00	Drosophila melanogaster	TGTCAD	HTGACA	B1H Zhu et al.(2011) Vis_SOLEXA_FBgn0033748	0.657	0.527
Tgif2 M00521_2.00	Mus musculus	NNTGACANNN	NNNTGTCANN	PBM Berger et al.(2008) Tgif2_3451	0.657	0.509
TGIF2 M03123_2.00	Homo sapiens	TGACAGSTGTCA	TGACASCTGTCA	SELEX Jolma et al.(2013) TGIF2_1	0.657	0.509
TGIF2 M05032_2.00	Homo sapiens	TGACABVTGTCA	TGACABVTGTCA	SELEX Yin et al.(2017) TGIF2_eDBD_HT-SELEX	0.657	0.509
TGIF2 M05034_2.00	Homo sapiens	DTGACANN	NNTGTCAH	SELEX Yin et al.(2017) TGIF2_FL_HT-SELEX	0.657	0.509
TGIF2 M05033_2.00	Homo sapiens	TGWCABVTGWCA	TGWCABVTGWCA	SELEX Yin et al.(2017) TGIF2_eDBD_Methyl-HT-SELEX	0.657	0.509
TGIF2 M05035_2.00	Homo sapiens	DTGACANN	NNTGTCAH	SELEX Yin et al.(2017) TGIF2_FL_Methyl-HT-SELEX	0.657	0.509
Tgif1 M00500_2.00	Mus musculus	NNTGACANNN	NNNTGTCANN	PBM Berger et al.(2008) Tgif1_2342	0.624	0.527
TGIF1 M03223_2.00	Homo sapiens	TGACAGCTGTCA	TGACAGCTGTCA	SELEX Jolma et al.(2013) TGIF1_1	0.624	0.527
TGIF1 M05317_2.00	Homo sapiens	TGACAGSTGTCA	TGACASCTGTCA	SELEX Yin et al.(2017) TGIF1_eDBD_HT-SELEX	0.624	0.527
TGIF1 M09159_2.00	Homo sapiens	TGACAGS	SCTGTCA	Misc Kulakovskiy et al.(2013) TGIF1_HUMAN.H11MO.0.A	0.624	0.527
Tgif1 M09211_2.00	Mus musculus	TGACAGBNV	BNVCTGTCA	Misc Kulakovskiy et al.(2013) TGIF1_MOUSE.H11MO.0.A	0.624	0.527
TGIF1 M10740_2.00	Homo sapiens	WHNTGACARST	ASYTGTCANDW	Transfac Matys et al.(2006) V$TGIF_01	0.624	0.527
TGIF1 M05318_2.00	Homo sapiens	TGACAKVTGTCA	TGACABMTGTCA	SELEX Yin et al.(2017) TGIF1_eDBD_Methyl-HT-SELEX	0.624	0.527
For this family, TFs with SR scores > 0.599* will likely have a similar motif*

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
ENSAMEP00000008674	Homeodomain	268	325	NKKRGIFPKVATNIMRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRI
ENSAMEP00000008689	Homeodomain	330	366	CSQHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRI

Links
Other Homeodomain family TFs
Other *Ailuropoda melanoleuca* TFs

1966 Related TFs

Name	Species	Gene ID	Motif Evidence	SR Score	Action
ENSACAG00000022883	Anolis carolinensis	ENSACAG00000022883	I	0.000
ENSCJAG00000033914	Callithrix jacchus	ENSCJAG00000033914	I	0.000
POGK	Homo sapiens	ENSG00000143157	I	0.000
ENSXETG00000008236_CONSTRUCT	PBM CONSTRUCTS	ENSXETG00000008236_CONSTRUCT	D	0.000
ENSPSIG00000001402	Pelodiscus sinensis	ENSPSIG00000001402	I	0.000

ENSAMEG00000008199 (Ailuropoda melanoleuca) Homeodomain

TF Information

Directly determined binding motifs

Motifs from related TFs

DNA Binding Domains

Links

1966 Related TFs

ENSAMEG00000008199 **(Ailuropoda melanoleuca)
Homeodomain**