pknox2 (Takifugu rubripes)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSTRUG00000003012 T216627_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Pknox2
M00468_2.00 		Mus musculus
NNNGACRNNN
NNNYGTCNNN		 PBM
Berger et al.(2008)
Pknox2_3077 		0.867 1.000
PKNOX2
M03195_2.00 		Homo sapiens
TGACAGSTGTCA
TGACASCTGTCA		 SELEX
Jolma et al.(2013)
PKNOX2_1 		0.867 1.000
Pknox2
M03270_2.00 		Mus musculus
TGACAGSTGTCA
TGACASCTGTCA		 SELEX
Jolma et al.(2013)
Pknox2_1 		0.867 1.000
PKNOX2
M05246_2.00 		Homo sapiens
TGACABVTGTCA
TGACABVTGTCA		 SELEX
Yin et al.(2017)
PKNOX2_eDBD_HT-SELEX 		0.867 1.000
PKNOX2
M05247_2.00 		Homo sapiens
TGACASSTGTCA
TGACASSTGTCA		 SELEX
Yin et al.(2017)
PKNOX2_eDBD_Methyl-HT-SELEX 		0.867 1.000
Pknox1
M00399_2.00 		Mus musculus
HGACRNNN
NNNYGTCD		 PBM
Berger et al.(2008)
Pknox1_2364 		0.867 0.964
PKNOX1
M03178_2.00 		Homo sapiens
TGACAGSTGTCA
TGACASCTGTCA		 SELEX
Jolma et al.(2013)
PKNOX1_1 		0.867 0.964
PKNOX1
M05206_2.00 		Homo sapiens
TGACASSTGTCA
TGACASSTGTCA		 SELEX
Yin et al.(2017)
PKNOX1_eDBD_HT-SELEX 		0.867 0.964
PKNOX1
M05208_2.00 		Homo sapiens
TGACAGCTGTCA
TGACAGCTGTCA		 SELEX
Yin et al.(2017)
PKNOX1_FL_HT-SELEX 		0.867 0.964
PKNOX1
M09150_2.00 		Homo sapiens
TGABTGRCRGV
BCYGYCAVTCA		 Misc
Kulakovskiy et al.(2013)
PKNX1_HUMAN.H11MO.0.B 		0.867 0.964
Pknox1
M09175_2.00 		Mus musculus
TGABTGRCRGV
BCYGYCAVTCA		 Misc
Kulakovskiy et al.(2013)
PKNX1_MOUSE.H11MO.0.A 		0.867 0.964
PKNOX1
M10712_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PREP1_Q3 		0.867 0.964
PKNOX1
M05207_2.00 		Homo sapiens
YGWCASSTGWCR
YGWCASSTGWCR		 SELEX
Yin et al.(2017)
PKNOX1_eDBD_Methyl-HT-SELEX 		0.867 0.964
PKNOX1
M05209_2.00 		Homo sapiens
TGACABVTGTCA
TGACABVTGTCA		 SELEX
Yin et al.(2017)
PKNOX1_FL_Methyl-HT-SELEX 		0.867 0.964
Meis1
M00407_2.00 		Mus musculus
NTGACADNN
NNHTGTCAN		 PBM
Berger et al.(2008)
Meis1_2335 		0.751 0.727
Meis2
M00437_2.00 		Mus musculus
NTGACANNN
NNNTGTCAN		 PBM
Berger et al.(2008)
Mrg1_2246 		0.751 0.727
Meis3
M00488_2.00 		Mus musculus
NTGACANNN
NNNTGTCAN		 PBM
Berger et al.(2008)
Mrg2_2302 		0.751 0.727
MEIS1
M03165_2.00 		Homo sapiens
NTGACAN
NTGTCAN		 SELEX
Jolma et al.(2013)
MEIS1_1 		0.751 0.727
MEIS2
M03147_2.00 		Homo sapiens
WTGACAGSTGTCAM
KTGACASCTGTCAW		 SELEX
Jolma et al.(2013)
MEIS2_1 		0.751 0.727
MEIS2
M03148_2.00 		Homo sapiens
DTGACAGS
SCTGTCAH		 SELEX
Jolma et al.(2013)
MEIS2_2 		0.751 0.727
Meis2
M03261_2.00 		Mus musculus
NTGACAN
NTGTCAN		 SELEX
Jolma et al.(2013)
Meis2_1 		0.751 0.727
Meis2
M03262_2.00 		Mus musculus
TGACAGSTGTCA
TGACASCTGTCA		 SELEX
Jolma et al.(2013)
Meis2_2 		0.751 0.727
Meis3
M03279_2.00 		Mus musculus
NTGACAN
NTGTCAN		 SELEX
Jolma et al.(2013)
Meis3_1 		0.751 0.727
Meis3
M03280_2.00 		Mus musculus
TGACAGSTGTCA
TGACASCTGTCA		 SELEX
Jolma et al.(2013)
Meis3_2 		0.751 0.727
MEIS2
M02740_2.00 		Homo sapiens
TGACASSTGTC
GACASSTGTCA		 SELEX
Jolma et al.(2010)
MEIS2_dimer 		0.751 0.727
MEIS2
M02741_2.00 		Homo sapiens
GGACAKNT
ANMTGTCC		 SELEX
Jolma et al.(2010)
MEIS2_monomer 		0.751 0.727
MEIS2
M05138_2.00 		Homo sapiens
TGACASSTGTCA
TGACASSTGTCA		 SELEX
Yin et al.(2017)
MEIS2_eDBD_HT-SELEX 		0.751 0.727
MEIS2
M05140_2.00 		Homo sapiens
TGACASSTGTCA
TGACASSTGTCA		 SELEX
Yin et al.(2017)
MEIS2_FL_HT-SELEX 		0.751 0.727
hth
M06490_2.00 		Drosophila melanogaster
TGACAK
MTGTCA		 B1H
Mathelier et al.(2014)
MA0227.1 		0.751 0.727
hth
M06252_2.00 		Drosophila melanogaster
TGTCA
TGACA		 B1H
Zhu et al.(2011)
Hth_Cell_FBgn0001235 		0.751 0.727
hth
M06253_2.00 		Drosophila melanogaster
NNTGACAD
HTGTCANN		 B1H
Zhu et al.(2011)
hth_SOLEXA_2_FBgn0001235 		0.751 0.727
hth
M06254_2.00 		Drosophila melanogaster
NTGACA
TGTCAN		 B1H
Zhu et al.(2011)
Hth_SOLEXA_FBgn0001235 		0.751 0.727
MEIS1
M09148_2.00 		Homo sapiens
NTGATTDATDDB
VHHATHAATCAN		 Misc
Kulakovskiy et al.(2013)
MEIS1_HUMAN.H11MO.0.A 		0.751 0.727
MEIS2
M09143_2.00 		Homo sapiens
HTGACAGBTKTBM
KVAMAVCTGTCAD		 Misc
Kulakovskiy et al.(2013)
MEIS2_HUMAN.H11MO.0.B 		0.751 0.727
Meis1
M09178_2.00 		Mus musculus
NTGATTDATDDB
VHHATHAATCAN		 Misc
Kulakovskiy et al.(2013)
MEIS1_MOUSE.H11MO.0.A 		0.751 0.727
Meis2
M09189_2.00 		Mus musculus
HTGACAGBTKTBM
KVAMAVCTGTCAD		 Misc
Kulakovskiy et al.(2013)
MEIS2_MOUSE.H11MO.0.B 		0.751 0.727
Meis1
M09568_2.00 		Mus musculus
VBTGWCASNN
NNSTGWCAVB		 Misc
Heinz et al.(2010)
MastCells-Meis1_GSE48085 		0.751 0.727
MEIS1
M10709_2.00 		Homo sapiens
NHNTGACAGNDN
NHNCTGTCANDN		 Transfac
Matys et al.(2006)
V$MEIS1_01 		0.751 0.727
MEIS1
M10710_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MEIS1_06 		0.751 0.727
MEIS2
M05139_2.00 		Homo sapiens
YGACASSYGHCR
YGDCRSSTGTCR		 SELEX
Yin et al.(2017)
MEIS2_eDBD_Methyl-HT-SELEX 		0.751 0.727
MEIS2
M05141_2.00 		Homo sapiens
TGACASSTGTCA
TGACASSTGTCA		 SELEX
Yin et al.(2017)
MEIS2_FL_Methyl-HT-SELEX 		0.751 0.727
unc-62
M02185_2.00 		Caenorhabditis elegans
NHDAHANNN
NNNTDTHDN		 PBM
Weirauch et al.(2014)
pTH5781 		0.738 0.655
Tgif2
M00521_2.00 		Mus musculus
NNTGACANNN
NNNTGTCANN		 PBM
Berger et al.(2008)
Tgif2_3451 		0.633 0.527
TGIF2
M03123_2.00 		Homo sapiens
TGACAGSTGTCA
TGACASCTGTCA		 SELEX
Jolma et al.(2013)
TGIF2_1 		0.633 0.527
TGIF2
M05032_2.00 		Homo sapiens
TGACABVTGTCA
TGACABVTGTCA		 SELEX
Yin et al.(2017)
TGIF2_eDBD_HT-SELEX 		0.633 0.527
TGIF2
M05034_2.00 		Homo sapiens
DTGACANN
NNTGTCAH		 SELEX
Yin et al.(2017)
TGIF2_FL_HT-SELEX 		0.633 0.527
TGIF2
M05033_2.00 		Homo sapiens
TGWCABVTGWCA
TGWCABVTGWCA		 SELEX
Yin et al.(2017)
TGIF2_eDBD_Methyl-HT-SELEX 		0.633 0.527
TGIF2
M05035_2.00 		Homo sapiens
DTGACANN
NNTGTCAH		 SELEX
Yin et al.(2017)
TGIF2_FL_Methyl-HT-SELEX 		0.633 0.527
Tgif1
M00500_2.00 		Mus musculus
NNTGACANNN
NNNTGTCANN		 PBM
Berger et al.(2008)
Tgif1_2342 		0.631 0.527
TGIF1
M03223_2.00 		Homo sapiens
TGACAGCTGTCA
TGACAGCTGTCA		 SELEX
Jolma et al.(2013)
TGIF1_1 		0.631 0.527
TGIF1
M05317_2.00 		Homo sapiens
TGACAGSTGTCA
TGACASCTGTCA		 SELEX
Yin et al.(2017)
TGIF1_eDBD_HT-SELEX 		0.631 0.527
TGIF1
M09159_2.00 		Homo sapiens
TGACAGS
SCTGTCA		 Misc
Kulakovskiy et al.(2013)
TGIF1_HUMAN.H11MO.0.A 		0.631 0.527
Tgif1
M09211_2.00 		Mus musculus
TGACAGBNV
BNVCTGTCA		 Misc
Kulakovskiy et al.(2013)
TGIF1_MOUSE.H11MO.0.A 		0.631 0.527
TGIF1
M10740_2.00 		Homo sapiens
WHNTGACARST
ASYTGTCANDW		 Transfac
Matys et al.(2006)
V$TGIF_01 		0.631 0.527
TGIF1
M05318_2.00 		Homo sapiens
TGACAKVTGTCA
TGACABMTGTCA		 SELEX
Yin et al.(2017)
TGIF1_eDBD_Methyl-HT-SELEX 		0.631 0.527
achi
M03860_2.00 		Drosophila melanogaster
TGACAD
HTGTCA		 SELEX
Nitta et al.(2015)
achi_1 		0.622 0.509
achi
M03861_2.00 		Drosophila melanogaster
TGACAGMTGTCA
TGACAKCTGTCA		 SELEX
Nitta et al.(2015)
achi_2 		0.622 0.509
achi
M03862_2.00 		Drosophila melanogaster
TGACAGNNNNNNYGTCA
TGACRNNNNNNCTGTCA		 SELEX
Nitta et al.(2015)
achi_3 		0.622 0.509
vis
M03859_2.00 		Drosophila melanogaster
TGACAS
STGTCA		 SELEX
Nitta et al.(2015)
vis_1 		0.622 0.509
vis
M06534_2.00 		Drosophila melanogaster
TGACAB
BTGTCA		 B1H
Mathelier et al.(2014)
MA0252.1 		0.622 0.509
achi
M06535_2.00 		Drosophila melanogaster
TGACAG
CTGTCA		 B1H
Mathelier et al.(2014)
MA0207.1 		0.622 0.509
achi
M06345_2.00 		Drosophila melanogaster
TGTCADW
WHTGACA		 B1H
Zhu et al.(2011)
Achi_Cell_FBgn0033749 		0.622 0.509
achi
M06346_2.00 		Drosophila melanogaster
HTGACA
TGTCAD		 B1H
Zhu et al.(2011)
Achi_SOLEXA_FBgn0033749 		0.622 0.509
vis
M06343_2.00 		Drosophila melanogaster
TGTCA
TGACA		 B1H
Zhu et al.(2011)
Vis_Cell_FBgn0033748 		0.622 0.509
vis
M06344_2.00 		Drosophila melanogaster
TGTCAD
HTGACA		 B1H
Zhu et al.(2011)
Vis_SOLEXA_FBgn0033748 		0.622 0.509
TGIF2LX
M03171_2.00 		Homo sapiens
TGACAGSTGTCA
TGACASCTGTCA		 SELEX
Jolma et al.(2013)
TGIF2LX_1 		0.601 0.509
TGIF2LX
M05191_2.00 		Homo sapiens
TGACABVTGTCA
TGACABVTGTCA		 SELEX
Yin et al.(2017)
TGIF2LX_eDBD_HT-SELEX 		0.601 0.509
TGIF2LX
M05193_2.00 		Homo sapiens
TGACASSTGTCA
TGACASSTGTCA		 SELEX
Yin et al.(2017)
TGIF2LX_FL_HT-SELEX 		0.601 0.509
TGIF2LX
M05192_2.00 		Homo sapiens
TGACABVTGTCA
TGACABVTGTCA		 SELEX
Yin et al.(2017)
TGIF2LX_eDBD_Methyl-HT-SELEX 		0.601 0.509
TGIF2LX
M05194_2.00 		Homo sapiens
TGACASSTGTCA
TGACASSTGTCA		 SELEX
Yin et al.(2017)
TGIF2LX_FL_Methyl-HT-SELEX 		0.601 0.509
TGIF2LY
M05313_2.00 		Homo sapiens
TGACABVTGTCA
TGACABVTGTCA		 SELEX
Yin et al.(2017)
TGIF2LY_eDBD_HT-SELEX 		0.601 0.491
TGIF2LY
M05314_2.00 		Homo sapiens
YGACABVTGTCR
YGACABVTGTCR		 SELEX
Yin et al.(2017)
TGIF2LY_eDBD_Methyl-HT-SELEX 		0.601 0.491
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSTRUP00000007036 Homeodomain 206 263
ENSTRUP00000007037 Homeodomain 288 345
ENSTRUP00000007038 Homeodomain 289 346
ENSTRUP00000007039 Homeodomain 204 261

Links

Other Homeodomain family TFs
Other Takifugu rubripes TFs

799 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
nAv.1.0.1.g09678 Acanthocheilonema viteae nAv.1.0.1.g09678 I 0.000
ACYPI000169 Acyrthosiphon pisum ACYPI000169 I 0.000
AAEL002359 Aedes aegypti AAEL002359 I 0.000
ANCCEY_12232 Ancylostoma ceylanicum ANCCEY_12232 N 0.000
ANCDUO_06286 Ancylostoma duodenale ANCDUO_06286 I 0.000
ASIM_0001287801 Anisakis simplex ASIM_0001287801 I 0.000
AARA001117 Anopheles arabiensis AARA001117 I 0.000
ACHR009241 Anopheles christyi ACHR009241 I 0.000
AEPI005805 Anopheles epiroticus AEPI005805 I 0.000
AGAP000061 Anopheles gambiae AGAP000061 I 0.000
AMEC018792 Anopheles melas AMEC018792 I 0.000
AMEM014370 Anopheles merus AMEM014370 I 0.000
ASU_08868 Ascaris suum ASU_08868 I 0.000
ASU_11536 Ascaris suum ASU_11536 I 0.000
Bm3512 Brugia malayi Bm3512 I 0.000
BTMF_0001011301 Brugia timori BTMF_0001011301 I 0.000
BXY_1717400 Bursaphelenchus xylophilus BXY_1717400 I 0.000
CBN23227 Caenorhabditis brenneri CBN23227 I 0.000
CBG11192 Caenorhabditis briggsae CBG11192 I 0.000
CBG05700 Caenorhabditis briggsae CBG05700 I 0.000
ceh-38 Caenorhabditis elegans WBGene00000459 I 0.000
CJA03729 Caenorhabditis japonica CJA03729 I 0.000
CRE26474 Caenorhabditis remanei CRE26474 I 0.000
CapteG52697 Capitella teleta CapteG52697 I 0.000
csin107314 Clonorchis sinensis csin107314 I 0.000
csin111721 Clonorchis sinensis csin111721 I 0.000
CpipJ_CPIJ006386 Culex pipiens CpipJ_CPIJ006386 I 0.000
CPIJ006386 Culex quinquefasciatus CPIJ006386 I 0.000
KGM_19875 Danaus plexippus KGM_19875 I 0.000
DAPPUDRAFT_32500 Daphnia pulex DAPPUDRAFT_32500 I 0.000
DICVIV_04514 Dictyocaulus viviparus DICVIV_04514 I 0.000
DICVIV_06959 Dictyocaulus viviparus DICVIV_06959 I 0.000
DME_0000092301 Dracunculus medinensis DME_0000092301 I 0.000
GG16442 Drosophila erecta FBgn0108673 I 0.000
GH24019 Drosophila grimshawi FBgn0131475 I 0.000
onecut Drosophila melanogaster FBgn0028996 D 0.000
GI14052 Drosophila mojavensis FBgn0136806 I 0.000
GL18146 Drosophila persimilis FBgn0155749 I 0.000
GA15133 Drosophila pseudoobscura FBgn0075158 I 0.000
GM26776 Drosophila sechellia FBgn0181629 I 0.000
GJ19930 Drosophila virilis FBgn0207072 I 0.000
GK13692 Drosophila willistoni FBgn0215700 I 0.000
GE14509 Drosophila yakuba FBgn0232113 I 0.000
ECANG7_03124 Echinococcus canadensis ECANG7_03124 I 0.000
EEL_0000016301 Elaeophora elaphi EEL_0000016301 I 0.000
EVEC_0000332701 Enterobius vermicularis EVEC_0000332701 I 0.000
ONECUT1 Erinaceus europaeus ENSEEUG00000010121 I 0.000
D915_15034 Fasciola hepatica D915_15034 I 0.000
GPLIN_001052100 Globodera pallida GPLIN_001052100 I 0.000
HCOI00211900 Haemonchus contortus HCOI00211900 I 0.000
HCOI01108700 Haemonchus contortus HCOI01108700 I 0.000
HCOI01220000 Haemonchus contortus HCOI01220000 I 0.000
HMEL003746 Heliconius melpomene HMEL003746 I 0.000
nLs.2.1.2.g01435 Litomosoides sigmodontis nLs.2.1.2.g01435 I 0.000
LOAG_18692 Loa loa LOAG_18692 I 0.000
LOAG_08712 Loa loa LOAG_08712 I 0.000
LotgiG199735 Lottia gigantea LotgiG199735 I 0.000
MhA1_Contig512.frz3.fgene1 Meloidogyne hapla MhA1_Contig512.frz3.fgene1 I 0.000
Minc16757 Meloidogyne incognita Minc16757 I 0.000
NECAME_06517 Necator americanus NECAME_06517 N 0.000
nOo.2.0.1.g10331 Onchocerca ochengi nOo.2.0.1.g10331 I 0.000
WBGene00247461 Onchocerca volvulus WBGene00247461 I 0.000
T265_01147 Opisthorchis viverrini T265_01147 I 0.000
T265_00751 Opisthorchis viverrini T265_00751 I 0.000
PPAI010631 Phlebotomus papatasi PPAI010631 I 0.000
scaffold421-EXSNAP2012.16 Pristionchus exspectatus scaffold421-EXSNAP2012.16 I 0.000
PXEA_0000259701 Protopolystoma xenopodis PXEA_0000259701 I 0.000
RSKR_0000794200 Rhabditophanes kr3021 RSKR_0000794200 N 0.000
RSKR_0000243000 Rhabditophanes kr3021 RSKR_0000243000 N 0.000
nRc.2.0.1.g02844 Romanomermis culicivorax nRc.2.0.1.g02844 N 0.000
SCUD_0001643701 Schistosoma curassoni SCUD_0001643701 I 0.000
A_00240 Schistosoma haematobium A_00240 I 0.000
Sjc_0006770 Schistosoma japonicum Sjc_0006770 I 0.000
Smp_013070 Schistosoma mansoni Smp_013070 I 0.000
Smp_196950 Schistosoma mansoni Smp_196950 I 0.000
SMRZ_0000163501 Schistosoma margrebowiei SMRZ_0000163501 I 0.000
SMTD_0000015201 Schistosoma mattheei SMTD_0000015201 I 0.000
SROB_0000769301 Schistosoma rodhaini SROB_0000769301 I 0.000
SMU15040257 Schmidtea mediterranea SMU15040257 I 0.000
L596_g1964 Steinernema carpocapsae L596_g1964 I 0.000
L596_g14922 Steinernema carpocapsae L596_g14922 I 0.000
L889_g27415 Steinernema feltiae L889_g27415 I 0.000
L889_g23716 Steinernema feltiae L889_g23716 I 0.000
L893_g27707 Steinernema glaseri L893_g27707 I 0.000
L893_g20975 Steinernema glaseri L893_g20975 I 0.000
L898_g28854 Steinernema monticolum L898_g28854 I 0.000
L898_g12845 Steinernema monticolum L898_g12845 I 0.000
L892_g29126 Steinernema scapterisci L892_g29126 N 0.000
SMUV_0000999101 Syphacia muris SMUV_0000999101 I 0.000
TASK_0000698901 Taenia asiatica TASK_0000698901 I 0.000
TsM_001008400 Taenia solium TsM_001008400 I 0.000
TCLT_0000532001 Thelazia callipaeda TCLT_0000532001 I 0.000
TCLT_0000779601 Thelazia callipaeda TCLT_0000779601 I 0.000
TMUE_s0014009100 Trichuris muris TMUE_s0014009100 I 0.000
TTRE_0000086601 Trichuris trichiura TTRE_0000086601 I 0.000
WUBG_00613 Wuchereria bancrofti WUBG_00613 N 0.000
onecut1.2 Xenopus tropicalis XB-GENE-1021674 I 0.000