ENSXMAG00000006176 (Xiphophorus maculatus)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSXMAG00000006176 T217181_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Pknox2
M00468_2.00
Mus musculus
NNNGACRNNN

NNNYGTCNNN
PBM
Berger et al.(2008)
Pknox2_3077
0.865 0.982
PKNOX2
M03195_2.00
Homo sapiens
TGACAGSTGTCA

TGACASCTGTCA
SELEX
Jolma et al.(2013)
PKNOX2_1
0.865 0.982
Pknox2
M03270_2.00
Mus musculus
TGACAGSTGTCA

TGACASCTGTCA
SELEX
Jolma et al.(2013)
Pknox2_1
0.865 0.982
PKNOX2
M05246_2.00
Homo sapiens
TGACABVTGTCA

TGACABVTGTCA
SELEX
Yin et al.(2017)
PKNOX2_eDBD_HT-SELEX
0.865 0.982
PKNOX2
M05247_2.00
Homo sapiens
TGACASSTGTCA

TGACASSTGTCA
SELEX
Yin et al.(2017)
PKNOX2_eDBD_Methyl-HT-SELEX
0.865 0.982
Pknox1
M00399_2.00
Mus musculus
HGACRNNN

NNNYGTCD
PBM
Berger et al.(2008)
Pknox1_2364
0.865 0.945
PKNOX1
M03178_2.00
Homo sapiens
TGACAGSTGTCA

TGACASCTGTCA
SELEX
Jolma et al.(2013)
PKNOX1_1
0.865 0.945
PKNOX1
M05206_2.00
Homo sapiens
TGACASSTGTCA

TGACASSTGTCA
SELEX
Yin et al.(2017)
PKNOX1_eDBD_HT-SELEX
0.865 0.945
PKNOX1
M05208_2.00
Homo sapiens
TGACAGCTGTCA

TGACAGCTGTCA
SELEX
Yin et al.(2017)
PKNOX1_FL_HT-SELEX
0.865 0.945
PKNOX1
M09150_2.00
Homo sapiens
TGABTGRCRGV

BCYGYCAVTCA
Misc
Kulakovskiy et al.(2013)
PKNX1_HUMAN.H11MO.0.B
0.865 0.945
Pknox1
M09175_2.00
Mus musculus
TGABTGRCRGV

BCYGYCAVTCA
Misc
Kulakovskiy et al.(2013)
PKNX1_MOUSE.H11MO.0.A
0.865 0.945
PKNOX1
M10712_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$PREP1_Q3
0.865 0.945
PKNOX1
M05207_2.00
Homo sapiens
YGWCASSTGWCR

YGWCASSTGWCR
SELEX
Yin et al.(2017)
PKNOX1_eDBD_Methyl-HT-SELEX
0.865 0.945
PKNOX1
M05209_2.00
Homo sapiens
TGACABVTGTCA

TGACABVTGTCA
SELEX
Yin et al.(2017)
PKNOX1_FL_Methyl-HT-SELEX
0.865 0.945
Meis1
M00407_2.00
Mus musculus
NTGACADNN

NNHTGTCAN
PBM
Berger et al.(2008)
Meis1_2335
0.751 0.727
Meis2
M00437_2.00
Mus musculus
NTGACANNN

NNNTGTCAN
PBM
Berger et al.(2008)
Mrg1_2246
0.751 0.727
Meis3
M00488_2.00
Mus musculus
NTGACANNN

NNNTGTCAN
PBM
Berger et al.(2008)
Mrg2_2302
0.751 0.727
MEIS1
M03165_2.00
Homo sapiens
NTGACAN

NTGTCAN
SELEX
Jolma et al.(2013)
MEIS1_1
0.751 0.727
MEIS2
M03147_2.00
Homo sapiens
WTGACAGSTGTCAM

KTGACASCTGTCAW
SELEX
Jolma et al.(2013)
MEIS2_1
0.751 0.727
MEIS2
M03148_2.00
Homo sapiens
DTGACAGS

SCTGTCAH
SELEX
Jolma et al.(2013)
MEIS2_2
0.751 0.727
Meis2
M03261_2.00
Mus musculus
NTGACAN

NTGTCAN
SELEX
Jolma et al.(2013)
Meis2_1
0.751 0.727
Meis2
M03262_2.00
Mus musculus
TGACAGSTGTCA

TGACASCTGTCA
SELEX
Jolma et al.(2013)
Meis2_2
0.751 0.727
Meis3
M03279_2.00
Mus musculus
NTGACAN

NTGTCAN
SELEX
Jolma et al.(2013)
Meis3_1
0.751 0.727
Meis3
M03280_2.00
Mus musculus
TGACAGSTGTCA

TGACASCTGTCA
SELEX
Jolma et al.(2013)
Meis3_2
0.751 0.727
MEIS2
M02740_2.00
Homo sapiens
TGACASSTGTC

GACASSTGTCA
SELEX
Jolma et al.(2010)
MEIS2_dimer
0.751 0.727
MEIS2
M02741_2.00
Homo sapiens
GGACAKNT

ANMTGTCC
SELEX
Jolma et al.(2010)
MEIS2_monomer
0.751 0.727
MEIS2
M05138_2.00
Homo sapiens
TGACASSTGTCA

TGACASSTGTCA
SELEX
Yin et al.(2017)
MEIS2_eDBD_HT-SELEX
0.751 0.727
MEIS2
M05140_2.00
Homo sapiens
TGACASSTGTCA

TGACASSTGTCA
SELEX
Yin et al.(2017)
MEIS2_FL_HT-SELEX
0.751 0.727
hth
M06490_2.00
Drosophila melanogaster
TGACAK

MTGTCA
B1H
Mathelier et al.(2014)
MA0227.1
0.751 0.727
hth
M06252_2.00
Drosophila melanogaster
TGTCA

TGACA
B1H
Zhu et al.(2011)
Hth_Cell_FBgn0001235
0.751 0.727
hth
M06253_2.00
Drosophila melanogaster
NNTGACAD

HTGTCANN
B1H
Zhu et al.(2011)
hth_SOLEXA_2_FBgn0001235
0.751 0.727
hth
M06254_2.00
Drosophila melanogaster
NTGACA

TGTCAN
B1H
Zhu et al.(2011)
Hth_SOLEXA_FBgn0001235
0.751 0.727
MEIS1
M09148_2.00
Homo sapiens
NTGATTDATDDB

VHHATHAATCAN
Misc
Kulakovskiy et al.(2013)
MEIS1_HUMAN.H11MO.0.A
0.751 0.727
MEIS2
M09143_2.00
Homo sapiens
HTGACAGBTKTBM

KVAMAVCTGTCAD
Misc
Kulakovskiy et al.(2013)
MEIS2_HUMAN.H11MO.0.B
0.751 0.727
Meis1
M09178_2.00
Mus musculus
NTGATTDATDDB

VHHATHAATCAN
Misc
Kulakovskiy et al.(2013)
MEIS1_MOUSE.H11MO.0.A
0.751 0.727
Meis2
M09189_2.00
Mus musculus
HTGACAGBTKTBM

KVAMAVCTGTCAD
Misc
Kulakovskiy et al.(2013)
MEIS2_MOUSE.H11MO.0.B
0.751 0.727
Meis1
M09568_2.00
Mus musculus
VBTGWCASNN

NNSTGWCAVB
Misc
Heinz et al.(2010)
MastCells-Meis1_GSE48085
0.751 0.727
MEIS1
M10709_2.00
Homo sapiens
NHNTGACAGNDN

NHNCTGTCANDN
Transfac
Matys et al.(2006)
V$MEIS1_01
0.751 0.727
MEIS1
M10710_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$MEIS1_06
0.751 0.727
MEIS2
M05139_2.00
Homo sapiens
YGACASSYGHCR

YGDCRSSTGTCR
SELEX
Yin et al.(2017)
MEIS2_eDBD_Methyl-HT-SELEX
0.751 0.727
MEIS2
M05141_2.00
Homo sapiens
TGACASSTGTCA

TGACASSTGTCA
SELEX
Yin et al.(2017)
MEIS2_FL_Methyl-HT-SELEX
0.751 0.727
unc-62
M02185_2.00
Caenorhabditis elegans
NHDAHANNN

NNNTDTHDN
PBM
Weirauch et al.(2014)
pTH5781
0.738 0.655
Tgif1
M00500_2.00
Mus musculus
NNTGACANNN

NNNTGTCANN
PBM
Berger et al.(2008)
Tgif1_2342
0.631 0.527
TGIF1
M03223_2.00
Homo sapiens
TGACAGCTGTCA

TGACAGCTGTCA
SELEX
Jolma et al.(2013)
TGIF1_1
0.631 0.527
TGIF1
M05317_2.00
Homo sapiens
TGACAGSTGTCA

TGACASCTGTCA
SELEX
Yin et al.(2017)
TGIF1_eDBD_HT-SELEX
0.631 0.527
TGIF1
M09159_2.00
Homo sapiens
TGACAGS

SCTGTCA
Misc
Kulakovskiy et al.(2013)
TGIF1_HUMAN.H11MO.0.A
0.631 0.527
Tgif1
M09211_2.00
Mus musculus
TGACAGBNV

BNVCTGTCA
Misc
Kulakovskiy et al.(2013)
TGIF1_MOUSE.H11MO.0.A
0.631 0.527
TGIF1
M10740_2.00
Homo sapiens
WHNTGACARST

ASYTGTCANDW
Transfac
Matys et al.(2006)
V$TGIF_01
0.631 0.527
TGIF1
M05318_2.00
Homo sapiens
TGACAKVTGTCA

TGACABMTGTCA
SELEX
Yin et al.(2017)
TGIF1_eDBD_Methyl-HT-SELEX
0.631 0.527
Tgif2
M00521_2.00
Mus musculus
NNTGACANNN

NNNTGTCANN
PBM
Berger et al.(2008)
Tgif2_3451
0.631 0.509
TGIF2
M03123_2.00
Homo sapiens
TGACAGSTGTCA

TGACASCTGTCA
SELEX
Jolma et al.(2013)
TGIF2_1
0.631 0.509
TGIF2
M05032_2.00
Homo sapiens
TGACABVTGTCA

TGACABVTGTCA
SELEX
Yin et al.(2017)
TGIF2_eDBD_HT-SELEX
0.631 0.509
TGIF2
M05034_2.00
Homo sapiens
DTGACANN

NNTGTCAH
SELEX
Yin et al.(2017)
TGIF2_FL_HT-SELEX
0.631 0.509
TGIF2
M05033_2.00
Homo sapiens
TGWCABVTGWCA

TGWCABVTGWCA
SELEX
Yin et al.(2017)
TGIF2_eDBD_Methyl-HT-SELEX
0.631 0.509
TGIF2
M05035_2.00
Homo sapiens
DTGACANN

NNTGTCAH
SELEX
Yin et al.(2017)
TGIF2_FL_Methyl-HT-SELEX
0.631 0.509
achi
M03860_2.00
Drosophila melanogaster
TGACAD

HTGTCA
SELEX
Nitta et al.(2015)
achi_1
0.620 0.491
achi
M03861_2.00
Drosophila melanogaster
TGACAGMTGTCA

TGACAKCTGTCA
SELEX
Nitta et al.(2015)
achi_2
0.620 0.491
achi
M03862_2.00
Drosophila melanogaster
TGACAGNNNNNNYGTCA

TGACRNNNNNNCTGTCA
SELEX
Nitta et al.(2015)
achi_3
0.620 0.491
vis
M03859_2.00
Drosophila melanogaster
TGACAS

STGTCA
SELEX
Nitta et al.(2015)
vis_1
0.620 0.491
vis
M06534_2.00
Drosophila melanogaster
TGACAB

BTGTCA
B1H
Mathelier et al.(2014)
MA0252.1
0.620 0.491
achi
M06535_2.00
Drosophila melanogaster
TGACAG

CTGTCA
B1H
Mathelier et al.(2014)
MA0207.1
0.620 0.491
achi
M06345_2.00
Drosophila melanogaster
TGTCADW

WHTGACA
B1H
Zhu et al.(2011)
Achi_Cell_FBgn0033749
0.620 0.491
achi
M06346_2.00
Drosophila melanogaster
HTGACA

TGTCAD
B1H
Zhu et al.(2011)
Achi_SOLEXA_FBgn0033749
0.620 0.491
vis
M06343_2.00
Drosophila melanogaster
TGTCA

TGACA
B1H
Zhu et al.(2011)
Vis_Cell_FBgn0033748
0.620 0.491
vis
M06344_2.00
Drosophila melanogaster
TGTCAD

HTGACA
B1H
Zhu et al.(2011)
Vis_SOLEXA_FBgn0033748
0.620 0.491
TGIF2LX
M03171_2.00
Homo sapiens
TGACAGSTGTCA

TGACASCTGTCA
SELEX
Jolma et al.(2013)
TGIF2LX_1
0.599 0.491
TGIF2LX
M05191_2.00
Homo sapiens
TGACABVTGTCA

TGACABVTGTCA
SELEX
Yin et al.(2017)
TGIF2LX_eDBD_HT-SELEX
0.599 0.491
TGIF2LX
M05193_2.00
Homo sapiens
TGACASSTGTCA

TGACASSTGTCA
SELEX
Yin et al.(2017)
TGIF2LX_FL_HT-SELEX
0.599 0.491
TGIF2LX
M05192_2.00
Homo sapiens
TGACABVTGTCA

TGACABVTGTCA
SELEX
Yin et al.(2017)
TGIF2LX_eDBD_Methyl-HT-SELEX
0.599 0.491
TGIF2LX
M05194_2.00
Homo sapiens
TGACASSTGTCA

TGACASSTGTCA
SELEX
Yin et al.(2017)
TGIF2LX_FL_Methyl-HT-SELEX
0.599 0.491
TGIF2LY
M05313_2.00
Homo sapiens
TGACABVTGTCA

TGACABVTGTCA
SELEX
Yin et al.(2017)
TGIF2LY_eDBD_HT-SELEX
0.599 0.473
TGIF2LY
M05314_2.00
Homo sapiens
YGACABVTGTCR

YGACABVTGTCR
SELEX
Yin et al.(2017)
TGIF2LY_eDBD_Methyl-HT-SELEX
0.599 0.473
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSXMAP00000006196 Homeodomain 289 346

Links

Other Homeodomain family TFs
Other Xiphophorus maculatus TFs

798 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
PVAR5_3492 Byssochlamys spectabilis PVAR5_3492 N 0.000
A1O1_00830 Capronia coronata A1O1_00830 N 0.000
Z519_11982 Cladophialophora bantiana Z519_11982 N 0.000
G647_04628 Cladophialophora carrionii G647_04628 N 0.000
A1O5_03055 Cladophialophora psammophila A1O5_03055 N 0.000
A1O7_04068 Cladophialophora yegresii A1O7_04068 N 0.000
HMPREF1541_09127 Cyphellophora europaea HMPREF1541_09127 N 0.000
EPUS_05070 Endocarpon pusillum EPUS_05070 N 0.000
HMPREF1120_06439 Exophiala dermatitidis HMPREF1120_06439 N 0.000
PV10_00320 Exophiala mesophila PV10_00320 N 0.000
PV06_04389 Exophiala oligosperma PV06_04389 N 0.000
PV11_05088 Exophiala sideris PV11_05088 N 0.000
PV08_10230 Exophiala spinifera PV08_10230 N 0.000
PV05_01354 Exophiala xenobiotica PV05_01354 N 0.000
Z517_11758 Fonsecaea pedrosoi Z517_11758 N 0.000
PMAA_080360 Penicillium marneffei PMAA_080360 N 0.000
Z518_01825 Rhinocladiella mackenziei Z518_01825 N 0.000
PMAA_080360 Talaromyces marneffei PMAA_080360 N 0.000
TSTA_114890 Talaromyces stipitatus TSTA_114890 N 0.000