Smp_027990 (Schistosoma mansoni)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 Smp_027990 T223458_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
scro
M03854_2.00 		Drosophila melanogaster
NNBRMGTGB
VCACKYVNN		 SELEX
Nitta et al.(2015)
scro_1 		0.858 0.930
ceh-24
M02181_2.00 		Caenorhabditis elegans
NNRAKWRNN
NNYWMTYNN		 PBM
Weirauch et al.(2014)
pTH6327 		0.851 0.860
Nkx2-1
M00385_2.00 		Mus musculus
NNRAGDRN
NYHCTYNN		 PBM
Berger et al.(2008)
Titf1_1722 		0.835 0.895
Nkx2-4
M00514_2.00 		Mus musculus
NNRAGDRBNN
NNVYHCTYNN		 PBM
Berger et al.(2008)
Nkx2-4_3074 		0.835 0.895
NKX2-1
M09146_2.00 		Homo sapiens
BTKGAGWGBN
NVCWCTCMAV		 Misc
Kulakovskiy et al.(2013)
NKX21_HUMAN.H11MO.0.A 		0.835 0.895
Nkx2-1
M09171_2.00 		Mus musculus
NBTKGAGWGB
VCWCTCMAVN		 Misc
Kulakovskiy et al.(2013)
NKX21_MOUSE.H11MO.0.A 		0.835 0.895
Nkx2-1
M09563_2.00 		Mus musculus
BTBRAGWGBH
DVCWCTYVAV		 Misc
Heinz et al.(2010)
LungAC-Nkx2.1_GSE43252 		0.835 0.895
NKX2-1
M10694_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TITF1_Q3 		0.835 0.895
NKX2-1
M10695_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TTF1_Q5_01 		0.835 0.895
NKX2-1
M10696_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TTF1_Q5 		0.835 0.895
NKX2-1
M10697_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TTF1_Q6 		0.835 0.895
NKX2-5
M00323_2.00 		Homo sapiens
NWYAAGTGSNN
NNSCACTTRWN		 PBM
Barrera et al.(2016)
NKX2-5_REF 		0.801 0.789
Nkx2-5
M00404_2.00 		Mus musculus
NNNRAGDRBN
NVYHCTYNNN		 PBM
Berger et al.(2008)
Nkx2-5_3436 		0.801 0.789
NKX2-5
M05346_2.00 		Homo sapiens
BHYAAGTGBN
NVCACTTRDV		 SELEX
Yin et al.(2017)
NKX2-5_FL_HT-SELEX 		0.801 0.789
Nkx2-5
M02686_2.00 		Mus musculus
WTAAKWK
MWMTTAW		 SELEX
Mathelier et al.(2014)
MA0063.1 		0.801 0.789
Nkx2-5
M08136_2.00 		Mus musculus
SYTGAGWGSYH
DRSCWCTCARS		 ChIP-seq
Mathelier et al.(2014)
MA0503.1 		0.801 0.789
NKX2-5
M09163_2.00 		Homo sapiens
BKRAGWGV
BCWCTYMV		 Misc
Kulakovskiy et al.(2013)
NKX25_HUMAN.H11MO.0.B 		0.801 0.789
Nkx2-5
M09177_2.00 		Mus musculus
NBYBRAGTGS
SCACTYVRVN		 Misc
Kulakovskiy et al.(2013)
NKX25_MOUSE.H11MO.0.A 		0.801 0.789
Nkx2-5
M09567_2.00 		Mus musculus
HBRAGWGBNN
NNVCWCTYVD		 Misc
Heinz et al.(2010)
HL1-Nkx2.5.biotin_GSE21529 		0.801 0.789
NKX2-5
M10742_2.00 		Homo sapiens
TYAAGTG
CACTTRA		 Transfac
Matys et al.(2006)
V$NKX25_01 		0.801 0.789
NKX2-5
M10743_2.00 		Homo sapiens
CWTAATTV
BAATTAWG		 Transfac
Matys et al.(2006)
V$NKX25_02 		0.801 0.789
NKX2-5
M10744_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NKX25_Q5 		0.801 0.789
NKX2-5
M10745_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NKX25_Q6 		0.801 0.789
NKX2-5
M00321_2.00 		Homo sapiens
HNAAGTRBNN
NNVYACTTND		 PBM
Barrera et al.(2016)
NKX2-5_R161P 		0.801 0.789
NKX2-5
M05347_2.00 		Homo sapiens
BTYAAGTGGN
NCCACTTRAV		 SELEX
Yin et al.(2017)
NKX2-5_FL_Methyl-HT-SELEX_1 		0.801 0.789
NKX2-5
M05348_2.00 		Homo sapiens
BTYAACGAB
VTCGTTRAV		 SELEX
Yin et al.(2017)
NKX2-5_FL_Methyl-HT-SELEX_2 		0.801 0.789
NKX2-5
M00322_2.00 		Homo sapiens
NNNRNNN
NNNYNNN		 PBM
Barrera et al.(2016)
NKX2-5_R190C 		0.801 0.772
NKX2-5
M00324_2.00 		Homo sapiens
NHNNNNN
NNNNNDN		 PBM
Barrera et al.(2016)
NKX2-5_T178M 		0.801 0.772
Nkx2-3
M00497_2.00 		Mus musculus
NNRAGDRNN
NNYHCTYNN		 PBM
Berger et al.(2008)
Nkx2-3_3435 		0.800 0.807
NKX2-3
M05042_2.00 		Homo sapiens
NNBAAGTGBN
NVCACTTVNN		 SELEX
Yin et al.(2017)
NKX2-3_eDBD_HT-SELEX 		0.800 0.807
NKX2-3
M05045_2.00 		Homo sapiens
BNBAAGTGBN
NVCACTTVNV		 SELEX
Yin et al.(2017)
NKX2-3_FL_HT-SELEX 		0.800 0.807
NKX2-3
M05043_2.00 		Homo sapiens
BNBAAGTGBN
NVCACTTVNV		 SELEX
Yin et al.(2017)
NKX2-3_eDBD_Methyl-HT-SELEX_1 		0.800 0.807
NKX2-3
M05044_2.00 		Homo sapiens
SDYAACGHB
VDCGTTRHS		 SELEX
Yin et al.(2017)
NKX2-3_eDBD_Methyl-HT-SELEX_2 		0.800 0.807
NKX2-3
M05046_2.00 		Homo sapiens
BNBAAGTGBN
NVCACTTVNV		 SELEX
Yin et al.(2017)
NKX2-3_FL_Methyl-HT-SELEX_1 		0.800 0.807
NKX2-3
M05047_2.00 		Homo sapiens
SWYAACSHB
VDSGTTRWS		 SELEX
Yin et al.(2017)
NKX2-3_FL_Methyl-HT-SELEX_2 		0.800 0.807
ceh-28
M08210_2.00 		Caenorhabditis elegans
AATCGATW
WATCGATT		 ChIP-seq
Contrino et al.(2012)
Mw138 		0.795 0.719
vnd
M06551_2.00 		Drosophila melanogaster
WYTCAAGTR
YACTTGARW		 B1H
Mathelier et al.(2014)
MA0253.1 		0.793 0.860
vnd
M06377_2.00 		Drosophila melanogaster
WYTCAAGTR
YACTTGARW		 B1H
Zhu et al.(2011)
Vnd_Cell_FBgn0003986 		0.793 0.860
vnd
M06378_2.00 		Drosophila melanogaster
KYTSAAGWGY
RCWCTTSARM		 B1H
Zhu et al.(2011)
vnd_FlyReg_FBgn0003986 		0.793 0.860
vnd
M06379_2.00 		Drosophila melanogaster
BTBAAGTR
YACTTVAV		 B1H
Zhu et al.(2011)
Vnd_SOLEXA_FBgn0003986 		0.793 0.860
vnd
M09683_2.00 		Drosophila melanogaster
TCAAGTGB
VCACTTGA		 Misc
Kulakovskiy et al.(2009)
vnd 		0.793 0.860
Nkx2-2
M00438_2.00 		Mus musculus
NNNRAGDRN
NYHCTYNNN		 PBM
Berger et al.(2008)
Nkx2-2_2823 		0.793 0.842
Nkx2-2
M09190_2.00 		Mus musculus
NTBRAGWGBBN
NVVCWCTYVAN		 Misc
Kulakovskiy et al.(2013)
NKX22_MOUSE.H11MO.0.A 		0.793 0.842
NKX2-2
M10681_2.00 		Homo sapiens
WTAAGTRBTT
AAVYACTTAW		 Transfac
Matys et al.(2006)
V$NKX22_01 		0.793 0.842
NKX2-2
M10682_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NKX2B_Q3_01 		0.793 0.842
NKX2-2
M10683_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NKX2B_Q3 		0.793 0.842
Nkx2-9
M00520_2.00 		Mus musculus
NNNRAGDRBN
NVYHCTYNNN		 PBM
Berger et al.(2008)
Nkx2-9_3082 		0.785 0.789
Nkx2-9
M00800_2.00 		Mus musculus
NNRAGDRBNN
NNVYHCTYNN		 PBM
Weirauch et al.(2013)
pTH2842 		0.785 0.789
Nkx2-9
M09215_2.00 		Mus musculus
BTCAAGKRB
VYMCTTGAV		 Misc
Kulakovskiy et al.(2013)
NKX28_MOUSE.H11MO.0.C 		0.785 0.789
tin
M00559_2.00 		Drosophila melanogaster
NWYAAGTGGNN
NNCCACTTRWN		 PBM
Busser et al.(2012a)
Tin 		0.771 0.667
tin
M03809_2.00 		Drosophila melanogaster
BTYAAGTGSN
NSCACTTRAV		 SELEX
Nitta et al.(2015)
tin_1 		0.771 0.667
tin
M06284_2.00 		Drosophila melanogaster
BTYAAGTG
CACTTRAV		 B1H
Zhu et al.(2011)
Tin_Cell_FBgn0004110 		0.771 0.667
tin
M06285_2.00 		Drosophila melanogaster
BCTCAAGTGSVN
NBSCACTTGAGV		 B1H
Zhu et al.(2011)
tin_FlyReg_FBgn0004110 		0.771 0.667
tin
M06286_2.00 		Drosophila melanogaster
BWYAAGTR
YACTTRWV		 B1H
Zhu et al.(2011)
Tin_SOLEXA_FBgn0004110 		0.771 0.667
tin
M08421_2.00 		Drosophila melanogaster
DBTCRAGTGS
SCACTYGAVH		 ChIP-chip
Mathelier et al.(2014)
MA0247.2 		0.771 0.667
NKX2-5
M00320_2.00 		Homo sapiens
NHBAAKWRN
NYWMTTVDN		 PBM
Barrera et al.(2016)
NKX2-5_K183E 		0.768 0.772
Nkx2-6
M00496_2.00 		Mus musculus
HYAAGTRBNN
NNVYACTTRD		 PBM
Berger et al.(2008)
Nkx2-6_3437 		0.762 0.737
ceh-22
M00376_2.00 		Caenorhabditis elegans
WBRAGTRBNN
NNVYACTYVW		 PBM
Berger et al.(2006)
Ceh-22 		0.759 0.807
NKX2-8
M00302_2.00 		Homo sapiens
NNRAGDRB
VYHCTYNN		 PBM
Barrera et al.(2016)
NKX2-8_REF 		0.754 0.772
NKX2-8
M05149_2.00 		Homo sapiens
BTSRAGTGBN
NVCACTYSAV		 SELEX
Yin et al.(2017)
NKX2-8_FL_HT-SELEX 		0.754 0.772
NKX2-8
M09145_2.00 		Homo sapiens
BTCAAGKRB
VYMCTTGAV		 Misc
Kulakovskiy et al.(2013)
NKX28_HUMAN.H11MO.0.C 		0.754 0.772
NKX2-8
M05150_2.00 		Homo sapiens
GCARTAACGACATC
GATGTCGTTAYTGC		 SELEX
Yin et al.(2017)
NKX2-8_FL_Methyl-HT-SELEX_1 		0.754 0.772
NKX2-8
M05151_2.00 		Homo sapiens
BTSAAGTGBN
NVCACTTSAV		 SELEX
Yin et al.(2017)
NKX2-8_FL_Methyl-HT-SELEX_2 		0.754 0.772
NKX2-8
M05152_2.00 		Homo sapiens
BTBAACGAB
VTCGTTVAV		 SELEX
Yin et al.(2017)
NKX2-8_FL_Methyl-HT-SELEX_3 		0.754 0.772
NKX2-8
M00301_2.00 		Homo sapiens
NNRAKDRB
VYHMTYNN		 PBM
Barrera et al.(2016)
NKX2-8_A94T 		0.754 0.754
Q24782_9CNID
M02206_2.00 		Eleutheria dichotoma
TTAATTAA
TTAATTAA		 PBM
Weirauch et al.(2014)
pTH5486 		0.611 0.509
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
Smp_027990.1:pep Homeodomain 453 509

Links

Other Homeodomain family TFs
Other Schistosoma mansoni TFs

835 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ACRE_005020 Acremonium chrysogenum ACRE_005020 N
BBA_03169 Beauveria bassiana BBA_03169 N
CHGG_10362 Chaetomium globosum CHGG_10362 N
CGGC5_12213 Colletotrichum gloeosporioides CGGC5_12213 N
CH063_13702 Colletotrichum higginsianum CH063_13702 N
CSUB01_09744 Colletotrichum sublineola CSUB01_09744 N
FFUJ_00815 Fusarium fujikuroi FFUJ_00815 N
FGRRES_00313 Fusarium graminearum FGRRES_00313 N
FOXG_00755 Fusarium oxysporum FOXG_00755 N
FPSE_08788 Fusarium pseudograminearum FPSE_08788 N
NechaG90227 Fusarium solani NechaG90227 N
FVEG_00760 Fusarium verticillioides FVEG_00760 N
GGTG_12994 Gaeumannomyces graminis GGTG_12994 N
CMQ_4592 Grosmannia clavigera CMQ_4592 N
MAC_05634 Metarhizium acridum MAC_05634 N
MAM_00980 Metarhizium album MAM_00980 N
MANI_028774 Metarhizium anisopliae MANI_028774 N
MBR_05136 Metarhizium brunneum MBR_05136 N
MGU_01536 Metarhizium guizhouense MGU_01536 N
MGU_08873 Metarhizium guizhouense MGU_08873 N
MGU_09482 Metarhizium guizhouense MGU_09482 N
X797_011022 Metarhizium robertsii X797_011022 N
X797_006938 Metarhizium robertsii X797_006938 N
fgenesh1_pm.sca_1_chr1_3_0000360 Nectria haematococca fgenesh1_pm.sca_1_chr1_3_0000360 N
F503_04378 Ophiostoma piceae uamh F503_04378 N
PODANS_3_6620 Podospora anserina PODANS_3_6620 N
SAPIO_CDS0995 Scedosporium apiospermum SAPIO_CDS0995 N
SPBR_01442 Sporothrix brasiliensis SPBR_01442 N
HMPREF1624_03405 Sporothrix schenckii HMPREF1624_03405 N
S40288_05293 Stachybotrys chartarum S40288_05293 N
S40285_03373 Stachybotrys chlorohalonata S40285_03373 N
THITE_2124406 Thielavia terrestris THITE_2124406 N
VDBG_07138 Verticillium albo atrum VDBG_07138 N
VDBG_07138 Verticillium alfalfae VDBG_07138 N