SPU_020565 (Strongylocentrotus purpuratus)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 SPU_020565 T223743_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
CDX1
M10761_2.00
Gallus gallus
BDBWAAK

MTTWVHV
Transfac
Matys et al.(2006)
V$CDXA_01
0.621 0.474
CDX1
M10762_2.00
Gallus gallus
WWWWMYR

YRKWAWW
Transfac
Matys et al.(2006)
V$CDXA_02
0.621 0.474
NEMVEDRAFT_v1g80394
M02151_2.00
Nematostella vectensis
NNYWATNHN

NDNATWRNN
PBM
Weirauch et al.(2014)
pTH5904
0.618 0.649
CDX4
M05129_2.00
Homo sapiens
VKTTTATKRCH

DGYMATAAAMB
SELEX
Yin et al.(2017)
CDX4_FL_HT-SELEX
0.614 0.456
Cdx4
M09197_2.00
Mus musculus
WGATTTATDRBH

DVYHATAAATCW
Misc
Kulakovskiy et al.(2013)
CDX4_MOUSE.H11MO.0.A
0.614 0.456
CDX4
M05130_2.00
Homo sapiens
BGTCGTAAAHN

NDTTTACGACV
SELEX
Yin et al.(2017)
CDX4_FL_Methyl-HT-SELEX_1
0.614 0.456
CDX4
M05131_2.00
Homo sapiens
VKTTTATKGCN

NGCMATAAAMB
SELEX
Yin et al.(2017)
CDX4_FL_Methyl-HT-SELEX_2
0.614 0.456
CDX2
M03196_2.00
Homo sapiens
KTTTATKRB

VYMATAAAM
SELEX
Jolma et al.(2013)
CDX2_1
0.609 0.474
CDX2
M05248_2.00
Homo sapiens
NDTWAYRRYN

NRYYRTWAHN
SELEX
Yin et al.(2017)
CDX2_eDBD_HT-SELEX_1
0.609 0.474
CDX2
M05249_2.00
Homo sapiens
NDWWATKRB

VYMATWWHN
SELEX
Yin et al.(2017)
CDX2_eDBD_HT-SELEX_2
0.609 0.474
CDX2
M08131_2.00
Homo sapiens
YTTTATKRCHB

VDGYMATAAAR
ChIP-seq
Mathelier et al.(2014)
MA0465.1
0.609 0.474
CDX2
M09152_2.00
Homo sapiens
DTTBATKGCHNB

VNDGCMATVAAH
Misc
Kulakovskiy et al.(2013)
CDX2_HUMAN.H11MO.0.A
0.609 0.474
CDX2
M10723_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CDX2_Q5_01
0.609 0.474
CDX2
M10724_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CDX2_Q5_02
0.609 0.474
CDX2
M10725_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CDX2_Q5
0.609 0.474
CDX2
M10726_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CDX2_Q6
0.609 0.474
CDX2
M05250_2.00
Homo sapiens
NRTCGTAWHBNN

NNVDWTACGAYN
SELEX
Yin et al.(2017)
CDX2_eDBD_Methyl-HT-SELEX
0.609 0.474
Cdx2
M00447_2.00
Mus musculus
NWWAYDRNN

NNYHRTWWN
PBM
Berger et al.(2008)
Cdx2_4272
0.609 0.456
Cdx2
M09193_2.00
Mus musculus
BTTTATKRCYBY

RVRGYMATAAAV
Misc
Kulakovskiy et al.(2013)
CDX2_MOUSE.H11MO.0.A
0.609 0.456
Cdx2
M09572_2.00
Mus musculus
NTTTTATKRC

GYMATAAAAN
Misc
Heinz et al.(2010)
mES-Cdx2_GSE14586
0.609 0.456
Cdx1
M00427_2.00
Mus musculus
NWWATDRNN

NNYHATWWN
PBM
Berger et al.(2008)
Cdx1_2245
0.609 0.439
CDX1
M03115_2.00
Homo sapiens
NTTTATKRB

VYMATAAAN
SELEX
Jolma et al.(2013)
CDX1_1
0.609 0.439
CDX1
M05018_2.00
Homo sapiens
VKTTTATKRCN

NGYMATAAAMB
SELEX
Yin et al.(2017)
CDX1_eDBD_HT-SELEX
0.609 0.439
CDX1
M09140_2.00
Homo sapiens
HCWTAAAD

HTTTAWGD
Misc
Kulakovskiy et al.(2013)
CDX1_HUMAN.H11MO.0.C
0.609 0.439
Cdx1
M09186_2.00
Mus musculus
HCWTAAAD

HTTTAWGD
Misc
Kulakovskiy et al.(2013)
CDX1_MOUSE.H11MO.0.C
0.609 0.439
CDX1
M10670_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CDX1_Q4
0.609 0.439
CDX1
M10671_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CDX1_Q5
0.609 0.439
CDX1
M05019_2.00
Homo sapiens
NGTCGTAAAWB

VWTTTACGACN
SELEX
Yin et al.(2017)
CDX1_eDBD_Methyl-HT-SELEX
0.609 0.439
NKX2-5
M00323_2.00
Homo sapiens
NWYAAGTGSNN

NNSCACTTRWN
PBM
Barrera et al.(2016)
NKX2-5_REF
0.604 0.474
Nkx2-5
M00404_2.00
Mus musculus
NNNRAGDRBN

NVYHCTYNNN
PBM
Berger et al.(2008)
Nkx2-5_3436
0.604 0.474
Nkx2-3
M00497_2.00
Mus musculus
NNRAGDRNN

NNYHCTYNN
PBM
Berger et al.(2008)
Nkx2-3_3435
0.604 0.474
NKX2-3
M05042_2.00
Homo sapiens
NNBAAGTGBN

NVCACTTVNN
SELEX
Yin et al.(2017)
NKX2-3_eDBD_HT-SELEX
0.604 0.474
NKX2-3
M05045_2.00
Homo sapiens
BNBAAGTGBN

NVCACTTVNV
SELEX
Yin et al.(2017)
NKX2-3_FL_HT-SELEX
0.604 0.474
NKX2-5
M05346_2.00
Homo sapiens
BHYAAGTGBN

NVCACTTRDV
SELEX
Yin et al.(2017)
NKX2-5_FL_HT-SELEX
0.604 0.474
Nkx2-5
M02686_2.00
Mus musculus
WTAAKWK

MWMTTAW
SELEX
Mathelier et al.(2014)
MA0063.1
0.604 0.474
Nkx2-5
M08136_2.00
Mus musculus
SYTGAGWGSYH

DRSCWCTCARS
ChIP-seq
Mathelier et al.(2014)
MA0503.1
0.604 0.474
NKX2-5
M09163_2.00
Homo sapiens
BKRAGWGV

BCWCTYMV
Misc
Kulakovskiy et al.(2013)
NKX25_HUMAN.H11MO.0.B
0.604 0.474
Nkx2-5
M09177_2.00
Mus musculus
NBYBRAGTGS

SCACTYVRVN
Misc
Kulakovskiy et al.(2013)
NKX25_MOUSE.H11MO.0.A
0.604 0.474
Nkx2-5
M09567_2.00
Mus musculus
HBRAGWGBNN

NNVCWCTYVD
Misc
Heinz et al.(2010)
HL1-Nkx2.5.biotin_GSE21529
0.604 0.474
NKX2-5
M10742_2.00
Homo sapiens
TYAAGTG

CACTTRA
Transfac
Matys et al.(2006)
V$NKX25_01
0.604 0.474
NKX2-5
M10743_2.00
Homo sapiens
CWTAATTV

BAATTAWG
Transfac
Matys et al.(2006)
V$NKX25_02
0.604 0.474
NKX2-5
M10744_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NKX25_Q5
0.604 0.474
NKX2-5
M10745_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NKX25_Q6
0.604 0.474
NKX2-5
M00321_2.00
Homo sapiens
HNAAGTRBNN

NNVYACTTND
PBM
Barrera et al.(2016)
NKX2-5_R161P
0.604 0.474
NKX2-5
M00324_2.00
Homo sapiens
NHNNNNN

NNNNNDN
PBM
Barrera et al.(2016)
NKX2-5_T178M
0.604 0.474
NKX2-3
M05043_2.00
Homo sapiens
BNBAAGTGBN

NVCACTTVNV
SELEX
Yin et al.(2017)
NKX2-3_eDBD_Methyl-HT-SELEX_1
0.604 0.474
NKX2-3
M05044_2.00
Homo sapiens
SDYAACGHB

VDCGTTRHS
SELEX
Yin et al.(2017)
NKX2-3_eDBD_Methyl-HT-SELEX_2
0.604 0.474
NKX2-3
M05046_2.00
Homo sapiens
BNBAAGTGBN

NVCACTTVNV
SELEX
Yin et al.(2017)
NKX2-3_FL_Methyl-HT-SELEX_1
0.604 0.474
NKX2-3
M05047_2.00
Homo sapiens
SWYAACSHB

VDSGTTRWS
SELEX
Yin et al.(2017)
NKX2-3_FL_Methyl-HT-SELEX_2
0.604 0.474
NKX2-5
M05347_2.00
Homo sapiens
BTYAAGTGGN

NCCACTTRAV
SELEX
Yin et al.(2017)
NKX2-5_FL_Methyl-HT-SELEX_1
0.604 0.474
NKX2-5
M05348_2.00
Homo sapiens
BTYAACGAB

VTCGTTRAV
SELEX
Yin et al.(2017)
NKX2-5_FL_Methyl-HT-SELEX_2
0.604 0.474
NKX2-5
M00322_2.00
Homo sapiens
NNNRNNN

NNNYNNN
PBM
Barrera et al.(2016)
NKX2-5_R190C
0.604 0.456
ceh-28
M08210_2.00
Caenorhabditis elegans
AATCGATW

WATCGATT
ChIP-seq
Contrino et al.(2012)
Mw138
0.603 0.439
tin
M00559_2.00
Drosophila melanogaster
NWYAAGTGGNN

NNCCACTTRWN
PBM
Busser et al.(2012a)
Tin
0.602 0.491
tin
M03809_2.00
Drosophila melanogaster
BTYAAGTGSN

NSCACTTRAV
SELEX
Nitta et al.(2015)
tin_1
0.602 0.491
tin
M06284_2.00
Drosophila melanogaster
BTYAAGTG

CACTTRAV
B1H
Zhu et al.(2011)
Tin_Cell_FBgn0004110
0.602 0.491
tin
M06285_2.00
Drosophila melanogaster
BCTCAAGTGSVN

NBSCACTTGAGV
B1H
Zhu et al.(2011)
tin_FlyReg_FBgn0004110
0.602 0.491
tin
M06286_2.00
Drosophila melanogaster
BWYAAGTR

YACTTRWV
B1H
Zhu et al.(2011)
Tin_SOLEXA_FBgn0004110
0.602 0.491
tin
M08421_2.00
Drosophila melanogaster
DBTCRAGTGS

SCACTYGAVH
ChIP-chip
Mathelier et al.(2014)
MA0247.2
0.602 0.491
cad
M03780_2.00
Drosophila melanogaster
NKTTTATKRCHB

VDGYMATAAAMN
SELEX
Nitta et al.(2015)
cad_1
0.601 0.421
cad
M03781_2.00
Drosophila melanogaster
NDTTTATKRCHN

NDGYMATAAAHN
SELEX
Nitta et al.(2015)
cad_2
0.601 0.421
cad
M03782_2.00
Drosophila melanogaster
NDTTTATKRCNB

VNGYMATAAAHN
SELEX
Nitta et al.(2015)
cad_3
0.601 0.421
cad
M03783_2.00
Drosophila melanogaster
NNTTTAYGRYNN

NNRYCRTAAANN
SELEX
Nitta et al.(2015)
cad_4
0.601 0.421
cad
M06223_2.00
Drosophila melanogaster
HTTWATTR

YAATWAAD
B1H
Zhu et al.(2011)
Cad_Cell_FBgn0000251
0.601 0.421
cad
M06224_2.00
Drosophila melanogaster
RBYVDAAMV

BKTTHBRVY
B1H
Zhu et al.(2011)
cad_FlyReg_FBgn0000251
0.601 0.421
cad
M06225_2.00
Drosophila melanogaster
NTTWATKR

YMATWAAN
B1H
Zhu et al.(2011)
Cad_SOLEXA_FBgn0000251
0.601 0.421
cad
M08420_2.00
Drosophila melanogaster
DTTTTATKRYY

RRYMATAAAAH
ChIP-chip
Mathelier et al.(2014)
MA0216.2
0.601 0.421
cad
M09580_2.00
Drosophila melanogaster
DTTTAYGRYN

NRYCRTAAAH
Misc
Heinz et al.(2010)
Drosophila-Embryos_modEncode
0.601 0.421
cad
M09674_2.00
Drosophila melanogaster
HTTTATKRBY

RVYMATAAAD
Misc
Kulakovskiy et al.(2009)
cad
0.601 0.421
cad
M10783_2.00
Drosophila melanogaster Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
I$CAD_Q6
0.601 0.421
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
SPU_020565-tr Homeodomain 220 276

Links

Other Homeodomain family TFs
Other Strongylocentrotus purpuratus TFs

513 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
Alligator_sinensis_CCG010046.1 Alligator sinensis Alligator_sinensis_CCG010046.1 N 0.000
ANCCAN_04327 Ancylostoma caninum ANCCAN_04327 N 0.000
ANCCEY_00583 Ancylostoma ceylanicum ANCCEY_00583 N 0.000
ANCDUO_17822 Ancylostoma duodenale ANCDUO_17822 N 0.000
ANCDUO_24135 Ancylostoma duodenale ANCDUO_24135 N 0.000
ANCDUO_27140 Ancylostoma duodenale ANCDUO_27140 N 0.000
AALB000417 Anopheles albimanus AALB000417 N 0.000
AALB008493 Anopheles albimanus AALB008493 N 0.000
AARA011013 Anopheles arabiensis AARA011013 N 0.000
AATE002453 Anopheles atroparvus AATE002453 N 0.000
ACHR005918 Anopheles christyi ACHR005918 N 0.000
ACHR009374 Anopheles christyi ACHR009374 N 0.000
ACOM023917 Anopheles coluzzii ACOM023917 N 0.000
ACUA008906 Anopheles culicifacies ACUA008906 N 0.000
ACUA010277 Anopheles culicifacies ACUA010277 N 0.000
ACUA018702 Anopheles culicifacies ACUA018702 N 0.000
ACUA028082 Anopheles culicifacies ACUA028082 N 0.000
ADAC010198 Anopheles darlingi ADAC010198 N 0.000
ADIR010892 Anopheles dirus ADIR010892 N 0.000
AEPI001841 Anopheles epiroticus AEPI001841 N 0.000
AEPI001845 Anopheles epiroticus AEPI001845 N 0.000
AEPI004511 Anopheles epiroticus AEPI004511 N 0.000
AFUN001004 Anopheles funestus AFUN001004 N 0.000
AGAP008569 Anopheles gambiae AGAP008569 I 0.000
AGAP011712 Anopheles gambiae AGAP011712 N 0.000
AMEC018160 Anopheles melas AMEC018160 N 0.000
AMEM005938 Anopheles merus AMEM005938 N 0.000
AMEM014364 Anopheles merus AMEM014364 N 0.000
AMIN000991 Anopheles minimus AMIN000991 N 0.000
AMIN008749 Anopheles minimus AMIN008749 N 0.000
AQUA000257 Anopheles quadriannulatus AQUA000257 N 0.000
AQUA010449 Anopheles quadriannulatus AQUA010449 N 0.000
ASTEI05183 Anopheles stephensi ASTEI05183 N 0.000
ASTEI10438 Anopheles stephensi ASTEI10438 N 0.000
Afo_R005342 Aptenodytes forsteri Afo_R005342 N 0.000
ACEP16054 Atta cephalotes ACEP16054 N 0.000
ACEP16128 Atta cephalotes ACEP16128 N 0.000
ACEP18777 Atta cephalotes ACEP18777 N 0.000
BGLB011455 Biomphalaria glabrata BGLB011455 N 0.000
BGIBMGA003174 Bombyx mori BGIBMGA003174 N 0.000
BGIBMGA006719 Bombyx mori BGIBMGA006719 N 0.000
BGIBMGA012898 Bombyx mori BGIBMGA012898 N 0.000
TBX15 Bos taurus ENSBTAG00000007767 I 0.000
Bm3498 Brugia malayi Bm3498 I 0.000
Brh_R011566 Buceros rhinoceros Brh_R011566 N 0.000
ENSCJAG00000000826 Callithrix jacchus ENSCJAG00000000826 N 0.000
Cflo_02417--XP_001121225.1_APIME Camponotus floridanus Cflo_02417--XP_001121225.1_APIME N 0.000
TBX10 Canis familiaris ENSCAFG00000011264 I 0.000
CLEC007098 Cimex lectularius CLEC007098 N 0.000
ENSCSAVG00000000786 Ciona savignyi ENSCSAVG00000000786 I 0.000
CpipJ_CPIJ000433 Culex pipiens CpipJ_CPIJ000433 N 0.000
CPIJ000433 Culex quinquefasciatus CPIJ000433 N 0.000
CGOC_0001264301 Cylicostephanus goldi CGOC_0001264301 N 0.000
KGM_15500 Danaus plexippus KGM_15500 N 0.000
YQE_06268 Dendroctonus ponderosae YQE_06268 N 0.000
YQE_10906 Dendroctonus ponderosae YQE_10906 N 0.000
DICVIV_10715 Dictyocaulus viviparus DICVIV_10715 N 0.000
ENSDORG00000012736 Dipodomys ordii ENSDORG00000012736 I 0.000
DME_0000818901 Dracunculus medinensis DME_0000818901 N 0.000
GF19461 Drosophila ananassae FBgn0096470 N 0.000
GG18707 Drosophila erecta FBgn0110916 N 0.000
GD16691 Drosophila simulans FBgn0188280 N 0.000
ECANG7_07880 Echinococcus canadensis ECANG7_07880 N 0.000
ENSETEG00000007920 Echinops telfairi ENSETEG00000007920 N 0.000
ECPE_0000395601 Echinostoma caproni ECPE_0000395601 N 0.000
EEL_0001013401 Elaeophora elaphi EEL_0001013401 N 0.000
D915_02167 Fasciola hepatica D915_02167 N 0.000
GPUH_0002190501 Gongylonema pulchrum GPUH_0002190501 N 0.000
HCOI01136500 Haemonchus contortus HCOI01136500 N 0.000
HHAL010563-PA Halyomorpha halys HHAL010563-PA N 0.000
Hsal_04126--XP_001122560.1_APIME Harpegnathos saltator Hsal_04126--XP_001122560.1_APIME I 0.000
Hsal_09269--XP_394607.3_APIME Harpegnathos saltator Hsal_09269--XP_394607.3_APIME N 0.000
HMEL004264 Heliconius melpomene HMEL004264 N 0.000
ISCW019287 Ixodes scapularis ISCW019287 N 0.000
LDEC010813 Leptinotarsa decemlineata LDEC010813 N 0.000
LCUP008640 Lucilia cuprina LCUP008640 N 0.000
MCINX015508 Melitaea cinxia MCINX015508 N 0.000
Tbx22 Mus musculus ENSMUSG00000031241 I 0.000
NECAME_19347 Necator americanus NECAME_19347 N 0.000
NBR_0000542501 Nippostrongylus brasiliensis NBR_0000542501 N 0.000
NBR_0001177301 Nippostrongylus brasiliensis NBR_0001177301 N 0.000
NBR_0002182001 Nippostrongylus brasiliensis NBR_0002182001 N 0.000
Ocbimv22013221m.g Octopus bimaculoides Ocbimv22013221m.g N 0.000
OESDEN_02780 Oesophagostomum dentatum OESDEN_02780 N 0.000
OESDEN_07954 Oesophagostomum dentatum OESDEN_07954 N 0.000
SNAPOd2T00025688001 Oikopleura dioica SNAPOd2T00025688001 N 0.000
OFLC_0001184101 Onchocerca flexuosa OFLC_0001184101 N 0.000
nOo.2.0.1.g12774 Onchocerca ochengi nOo.2.0.1.g12774 N 0.000
nOo.2.0.1.g12879 Onchocerca ochengi nOo.2.0.1.g12879 N 0.000
Ogr11253 Ophisaurus gracilis Ogr11253 N 0.000
ENSOANG00000020395 Ornithorhynchus anatinus ENSOANG00000020395 I 0.000
ENSOANG00000029773 Ornithorhynchus anatinus ENSOANG00000029773 I 0.000
PPAI002123 Phlebotomus papatasi PPAI002123 N 0.000
PPAI007567 Phlebotomus papatasi PPAI007567 N 0.000
PPA14512 Pristionchus pacificus PPA14512 N 0.000
ENSPCAG00000011680 Procavia capensis ENSPCAG00000011680 N 0.000
PXEA_0000704401 Protopolystoma xenopodis PXEA_0000704401 N 0.000
PXEA_0001803801 Protopolystoma xenopodis PXEA_0001803801 N 0.000
A_04261 Schistosoma haematobium A_04261 N 0.000
Smp_156650 Schistosoma mansoni Smp_156650 N 0.000
SMTD_0001100101 Schistosoma mattheei SMTD_0001100101 N 0.000
SINV10951 Solenopsis invicta SINV10951 N 0.000
SINV16738 Solenopsis invicta SINV16738 N 0.000
SINV17750 Solenopsis invicta SINV17750 I 0.000
SINV20004 Solenopsis invicta SINV20004 N 0.000
SPER_0002063901 Spirometra erinaceieuropaei SPER_0002063901 N 0.000
SPER_0002217601 Spirometra erinaceieuropaei SPER_0002217601 N 0.000
SPER_0003769001 Spirometra erinaceieuropaei SPER_0003769001 N 0.000
SPER_0003779701 Spirometra erinaceieuropaei SPER_0003779701 N 0.000
L892_g20532 Steinernema scapterisci L892_g20532 N 0.000
SVUK_0001851801 Strongylus vulgaris SVUK_0001851801 N 0.000
SMUV_0000075501 Syphacia muris SMUV_0000075501 N 0.000
TsM_001062700 Taenia solium TsM_001062700 N 0.000
TELCIR_17829 Teladorsagia circumcincta TELCIR_17829 N 0.000
TRE_0001207201 Trichobilharzia regenti TRE_0001207201 N 0.000
Tal_R004166 Tyto alba Tal_R004166 N 0.000
Tal_R010698 Tyto alba Tal_R010698 N 0.000
TBX5 Vicugna pacos ENSVPAG00000009445 I 0.000
ENSXMAG00000002873 Xiphophorus maculatus ENSXMAG00000002873 N 0.000
ENSXMAG00000005990 Xiphophorus maculatus ENSXMAG00000005990 N 0.000
L798_01365 Zootermopsis nevadensis L798_01365 N 0.000
L798_14238 Zootermopsis nevadensis L798_14238 N 0.000