six3.L (Xenopus laevis)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00046 (Homeobox) IPR001356 XB-GENE-478765 T230426_2.00 Misc (2018-Jan-19)

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Six3
M00483_2.00 		Mus musculus
NNNAYMN
NKRTNNN		 PBM
Berger et al.(2008)
Six3_1732 		0.867 1.000
SIX3
M05159_2.00 		Homo sapiens
NNYGATABBN
NVVTATCRNN		 SELEX
Yin et al.(2017)
SIX3_eDBD_HT-SELEX 		0.867 1.000
SIX3
M10698_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX3_Q6 		0.867 1.000
SIX3
M05160_2.00 		Homo sapiens
NNYGATABVB
VBVTATCRNN		 SELEX
Yin et al.(2017)
SIX3_eDBD_Methyl-HT-SELEX 		0.867 1.000
Optix
M02124_2.00 		Drosophila melanogaster
NNNNNDATMN
NKATHNNNNN		 PBM
Weirauch et al.(2014)
pTH5437 		0.867 0.947
Optix
M03850_2.00 		Drosophila melanogaster
TAATYTAATTA
TAATTARATTA		 SELEX
Nitta et al.(2015)
Optix_1 		0.867 0.947
Optix
M06526_2.00 		Drosophila melanogaster
TGATA
TATCA		 B1H
Mathelier et al.(2014)
MA0199.1 		0.867 0.947
Optix
M06327_2.00 		Drosophila melanogaster
HHVTGATA
TATCABDD		 B1H
Zhu et al.(2011)
Optix_Cell_FBgn0025360 		0.867 0.947
Optix
M06328_2.00 		Drosophila melanogaster
NNNTGATA
TATCANNN		 B1H
Zhu et al.(2011)
Optix_SOLEXA_FBgn0025360 		0.867 0.947
SIX6
M00326_2.00 		Homo sapiens
NNDATMB
VKATHNN		 PBM
Barrera et al.(2016)
SIX6_REF 		0.865 0.982
Six6
M00169_2.00 		Mus musculus
NNAYMNN
NNKRTNN		 PBM
Badis et al.(2009)
Six6_2267 		0.865 0.982
Six6
M00412_2.00 		Mus musculus
NNNTGATAYCN
NGRTATCANNN		 PBM
Berger et al.(2008)
Six6_2267 		0.865 0.982
SIX6
M05357_2.00 		Homo sapiens
NNYGATASVB
VBSTATCRNN		 SELEX
Yin et al.(2017)
SIX6_eDBD_HT-SELEX 		0.865 0.982
SIX6
M00325_2.00 		Homo sapiens
NNNDATMB
VKATHNNN		 PBM
Barrera et al.(2016)
SIX6_H141N 		0.865 0.982
SIX6
M05358_2.00 		Homo sapiens
VBVYAYCRNN
NNYGRTRBVB		 SELEX
Yin et al.(2017)
SIX6_eDBD_Methyl-HT-SELEX 		0.865 0.982
six3
M02102_2.00 		Oryzias latipes
NNDAYMBNNN
NNNVKRTHNN		 PBM
Weirauch et al.(2014)
pTH5928 		0.865 0.947
SIX6
M00327_2.00 		Homo sapiens
NHDAYMBNN
NNVKRTHDN		 PBM
Barrera et al.(2016)
SIX6_T165A 		0.859 0.965
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
AAF63242 Homeodomain 165 221
AAI69654 Homeodomain 165 221
AAI69660 Homeodomain 165 221

Links

Other Homeodomain family TFs
Other Xenopus laevis TFs

297 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
nAv.1.0.1.g09844 Acanthocheilonema viteae nAv.1.0.1.g09844 N
ACYPI001652 Acyrthosiphon pisum ACYPI001652 N
AAEL014670 Aedes aegypti AAEL014670 I
ENSAMEG00000000632 Ailuropoda melanoleuca ENSAMEG00000000632 I
ENSAMEG00000004909 Ailuropoda melanoleuca ENSAMEG00000004909 N
ENSAMEG00000014183 Ailuropoda melanoleuca ENSAMEG00000014183 I
Alligator_sinensis_CCG004256.1 Alligator sinensis Alligator_sinensis_CCG004256.1 N
Alligator_sinensis_CCG011289.1 Alligator sinensis Alligator_sinensis_CCG011289.1 I
Alligator_sinensis_CCG020461.1 Alligator sinensis Alligator_sinensis_CCG020461.1 I
Aqu1.216869 Amphimedon queenslandica Aqu1.216869 I
ENSAPLG00000010018 Anas platyrhynchos ENSAPLG00000010018 N
ENSAPLG00000016417 Anas platyrhynchos ENSAPLG00000016417 N
TEAD1 Anolis carolinensis ENSACAG00000004642 I
TEAD3 Anolis carolinensis ENSACAG00000009142 I
TEAD2 Anolis carolinensis ENSACAG00000017423 I
AALB006731 Anopheles albimanus AALB006731 N
ACHR008952 Anopheles christyi ACHR008952 I
ACOM033640 Anopheles coluzzii ACOM033640 N
AEPI008594 Anopheles epiroticus AEPI008594 I
AFAF008476 Anopheles farauti AFAF008476 N
AGAP000512 Anopheles gambiae AGAP000512 I
Afo_R008073 Aptenodytes forsteri Afo_R008073 N
Afo_R014607 Aptenodytes forsteri Afo_R014607 N
ENSAMXG00000010081 Astyanax mexicanus ENSAMXG00000010081 I
ENSAMXG00000013086 Astyanax mexicanus ENSAMXG00000013086 I
ENSAMXG00000013625 Astyanax mexicanus ENSAMXG00000013625 N
ACEP20936 Atta cephalotes ACEP20936 N
BGIBMGA001129 Bombyx mori BGIBMGA001129 I
ENSBTAP00000021752-D1 Bos grunniens ENSBTAP00000021752-D1 N
ENSP00000310701-D4 Bos grunniens ENSP00000310701-D4 I
ENSP00000349828-D1 Bos grunniens ENSP00000349828-D1 N
TEAD2 Bos taurus ENSBTAG00000016349 I
TEAD3 Bos taurus ENSBTAG00000019495 I
e_gw.291.69.1 Branchiostoma floridae e_gw.291.69.1 I
Bm3663 Brugia malayi Bm3663 N
Brh_R000244 Buceros rhinoceros Brh_R000244 N
BXY_1123500 Bursaphelenchus xylophilus BXY_1123500 N
CBN00477 Caenorhabditis brenneri CBN00477 I
CBN16859 Caenorhabditis brenneri CBN16859 I
CBG02541 Caenorhabditis briggsae CBG02541 I
egl-44 Caenorhabditis elegans WBGene00001208 I
CJA07640 Caenorhabditis japonica CJA07640 I
CRE26587 Caenorhabditis remanei CRE26587 N
TEAD2 Callithrix jacchus ENSCJAG00000000104 I
TEAD1 Callithrix jacchus ENSCJAG00000010263 I
TEAD3 Callithrix jacchus ENSCJAG00000015661 N
ENSCJAG00000018829 Callithrix jacchus ENSCJAG00000018829 I
TEAD4 Callithrix jacchus ENSCJAG00000023239 I
Aan_R003816 Calypte anna Aan_R003816 I
Aan_R006597 Calypte anna Aan_R006597 N
Aan_R012086 Calypte anna Aan_R012086 N
TEAD3 Canis familiaris ENSCAFG00000001326 I
TEAD2 Canis familiaris ENSCAFG00000003698 I
TEAD1 Canis familiaris ENSCAFG00000007976 I
TEAD2 Cavia porcellus ENSCPOG00000011572 I
TEAD4 Cavia porcellus ENSCPOG00000020720 I
Cmyd_10011168 Chelonia mydas Cmyd_10011168 N
Cmyd_10014175 Chelonia mydas Cmyd_10014175 I
ENSCSAG00000002642 Chlorocebus sabaeus ENSCSAG00000002642 I
ENSCSAG00000004676 Chlorocebus sabaeus ENSCSAG00000004676 I
TEAD1 Choloepus hoffmanni ENSCHOG00000001087 N
CLEC025393 Cimex lectularius CLEC025393 I
ENSCSAVG00000007634 Ciona savignyi ENSCSAVG00000007634 I
csin107014 Clonorchis sinensis csin107014 N
CpipJ_CPIJ013490 Culex pipiens CpipJ_CPIJ013490 I
CPIJ013490 Culex quinquefasciatus CPIJ013490 I
KGM_11943 Danaus plexippus KGM_11943 N
tead1a Danio rerio ENSDARG00000028159 I
tead1b Danio rerio ENSDARG00000059483 I
tead3b Danio rerio ENSDARG00000063649 I
tead3a Danio rerio ENSDARG00000074321 N
TEAD3 Dasypus novemcinctus ENSDNOG00000023623 I
TEAD4 Dasypus novemcinctus ENSDNOG00000030589 I
Tead1 Dipodomys ordii ENSDORG00000013529 N
GF20188 Drosophila ananassae FBgn0097195 I
GG17919 Drosophila erecta FBgn0110139 I
GH12522 Drosophila grimshawi FBgn0120001 I
sd Drosophila melanogaster FBgn0003345 D
GI14876 Drosophila mojavensis FBgn0137627 I
GL22923 Drosophila persimilis FBgn0160513 I
GA21152 Drosophila pseudoobscura FBgn0081140 I
GM22588 Drosophila sechellia FBgn0177458 I
GJ19539 Drosophila virilis FBgn0206682 I
GE17227 Drosophila yakuba FBgn0234705 I
ECANG7_01760 Echinococcus canadensis ECANG7_01760 I
TEAD1 Equus caballus ENSECAG00000008332 I
TEAD4 Equus caballus ENSECAG00000011303 I
TEAD3 Equus caballus ENSECAG00000015056 I
TEAD2 Equus caballus ENSECAG00000018010 I
ENSEEUG00000001836 Erinaceus europaeus ENSEEUG00000001836 I
TEAD2 Erinaceus europaeus ENSEEUG00000012244 I
D915_04738 Fasciola hepatica D915_04738 N
TEAD4 Felis catus ENSFCAG00000000150 N
TEAD2 Felis catus ENSFCAG00000001523 I
TEAD3 Felis catus ENSFCAG00000012905 I
ENSFALG00000003635 Ficedula albicollis ENSFALG00000003635 I
ENSGMOG00000004752 Gadus morhua ENSGMOG00000004752 N
ENSGMOG00000007916 Gadus morhua ENSGMOG00000007916 I
ENSGMOG00000010731 Gadus morhua ENSGMOG00000010731 I
ENSGMOG00000015271 Gadus morhua ENSGMOG00000015271 I
ENSGALG00000000953 Gallus gallus ENSGALG00000000953 I
TEAD1 Gallus gallus ENSGALG00000005415 I
TEAD4 Gallus gallus ENSGALG00000014342 N
tead1a Gasterosteus aculeatus ENSGACG00000003385 I
TEAD4 Gasterosteus aculeatus ENSGACG00000003761 N
tead3b Gasterosteus aculeatus ENSGACG00000005144 N
tead3a Gasterosteus aculeatus ENSGACG00000009758 I
tead1b Gasterosteus aculeatus ENSGACG00000015715 I
Gfo_R008443 Geospiza fortis Gfo_R008443 N
Gfo_R013616 Geospiza fortis Gfo_R013616 N
GPLIN_000239200 Globodera pallida GPLIN_000239200 N
TEAD3 Gorilla gorilla ENSGGOG00000001847 I
TEAD1 Gorilla gorilla ENSGGOG00000003412 N
TEAD4 Gorilla gorilla ENSGGOG00000006216 I
TEAD2 Gorilla gorilla ENSGGOG00000016367 I
HelroG146479 Helobdella robusta HelroG146479 I
HelroG156770 Helobdella robusta HelroG156770 N
HelroG91681 Helobdella robusta HelroG91681 N
TEAD3 Homo sapiens ENSG00000007866 D
TEAD2 Homo sapiens ENSG00000074219 D
TEAD1 Homo sapiens ENSG00000187079 D
TEAD4 Homo sapiens ENSG00000197905 D
XP_002160172.1 Hydra magnipapillata XP_002160172.1 N
HmN_000010800 Hymenolepis microstoma HmN_000010800 N
HmN_000661200 Hymenolepis microstoma HmN_000661200 N
ENSSTOG00000010621 Ictidomys tridecemlineatus ENSSTOG00000010621 I
ENSSTOG00000012695 Ictidomys tridecemlineatus ENSSTOG00000012695 I
ENSSTOG00000024296 Ictidomys tridecemlineatus ENSSTOG00000024296 I
ISCW001055 Ixodes scapularis ISCW001055 N
ENSLACG00000013349 Latimeria chalumnae ENSLACG00000013349 I
ENSLACG00000016444 Latimeria chalumnae ENSLACG00000016444 I
ENSLOCG00000004054 Lepisosteus oculatus ENSLOCG00000004054 I
ENSLOCG00000009736 Lepisosteus oculatus ENSLOCG00000009736 I
ENSLOCG00000016688 Lepisosteus oculatus ENSLOCG00000016688 I
LOAG_16930 Loa loa LOAG_16930 N
LotgiG210691 Lottia gigantea LotgiG210691 I
TEAD4 Loxodonta africana ENSLAFG00000006998 I
TEAD3 Loxodonta africana ENSLAFG00000014818 I
TEAD2 Loxodonta africana ENSLAFG00000016184 I
ENSMMUP00000031528 Macaca fascicularis ENSMMUP00000031528 I
ENSP00000349828 Macaca fascicularis ENSP00000349828 I
ENSP00000352926 Macaca fascicularis ENSP00000352926 N
ENSP00000355332 Macaca fascicularis ENSP00000355332 N
TEAD1 Macaca mulatta ENSMMUG00000010875 N
TEAD2 Macaca mulatta ENSMMUG00000014791 I
ENSMEUG00000006301 Macropus eugenii ENSMEUG00000006301 N
ENSMGAG00000000674 Meleagris gallopavo ENSMGAG00000000674 N
TEAD4 Meleagris gallopavo ENSMGAG00000013910 I
maker-nMf.1.1.scaf11367-augustus-gene-0.3 Meloidogyne floridensis maker-nMf.1.1.scaf11367-augustus-gene-0.3 N
MhA1_Contig1858.frz3.gene4 Meloidogyne hapla MhA1_Contig1858.frz3.gene4 N
Minc08587 Meloidogyne incognita Minc08587 N
TEAD3 Microcebus murinus ENSMICG00000000029 I
TEAD4 Microcebus murinus ENSMICG00000000108 I
ML20029a Mnemiopsis leidyi ML20029a N
fgenesh2_pg.scaffold_14000134 Monosiga brevicollis fgenesh2_pg.scaffold_14000134 N
MDOA005382 Musca domestica MDOA005382 I
ENSMPUG00000002689 Mustela putorius furo ENSMPUG00000002689 I
ENSMPUG00000003624 Mustela putorius furo ENSMPUG00000003624 I
ENSMPUG00000013114 Mustela putorius furo ENSMPUG00000013114 I
Tead3 Mus musculus ENSMUSG00000002249 N
Tead4 Mus musculus ENSMUSG00000030353 D
Tead2 Mus musculus ENSMUSG00000030796 D
Tead1 Mus musculus ENSMUSG00000055320 D
Myotis_brandtii_TEAD2_10017641 Myotis brandtii Myotis_brandtii_TEAD2_10017641 I
Myotis_brandtii_TEAD3_10017764 Myotis brandtii Myotis_brandtii_TEAD3_10017764 I
Myotis_brandtii_TEAD4_10028679 Myotis brandtii Myotis_brandtii_TEAD4_10028679 I
NV15824 Nasonia vitripennis NV15824 N
NEMVEDRAFT_v1g212385 Nematostella vectensis NEMVEDRAFT_v1g212385 N
ENSNLEG00000005091 Nomascus leucogenys ENSNLEG00000005091 I
ENSNLEG00000017672 Nomascus leucogenys ENSNLEG00000017672 N
TEAD4 Ochotona princeps ENSOPRG00000015460 N
nOo.2.0.1.g04457 Onchocerca ochengi nOo.2.0.1.g04457 N
ENSONIG00000005991 Oreochromis niloticus ENSONIG00000005991 N
ENSONIG00000011013 Oreochromis niloticus ENSONIG00000011013 I
ENSONIG00000012323 Oreochromis niloticus ENSONIG00000012323 I
ENSONIG00000014698 Oreochromis niloticus ENSONIG00000014698 I
TEAD4 Ornithorhynchus anatinus ENSOANG00000001389 I
TEAD2 Ornithorhynchus anatinus ENSOANG00000013933 N
TEAD1 Oryctolagus cuniculus ENSOCUG00000007955 I
TEAD2 Oryctolagus cuniculus ENSOCUG00000008758 I
TEAD4 Oryzias latipes ENSORLG00000002553 I
tead3b Oryzias latipes ENSORLG00000006370 N
tead1b Oryzias latipes ENSORLG00000007439 I
TEAD4 Otolemur garnettii ENSOGAG00000005199 I
ENSOARG00000008069 Ovis aries ENSOARG00000008069 I
ENSOARG00000012126 Ovis aries ENSOARG00000012126 I
ENSOARG00000012881 Ovis aries ENSOARG00000012881 N
TEAD2 Pan troglodytes ENSPTRG00000011290 I
TEAD1 Pan troglodytes ENSPTRG00000039896 N
ENSPANG00000023792 Papio anubis ENSPANG00000023792 I
PTRK_0001645900 Parastrongyloides trichosuri PTRK_0001645900 N
ENSTNIG00000008857_CONSTRUCT PBM CONSTRUCTS ENSTNIG00000008857_CONSTRUCT D
PHUM251000 Pediculus humanus PHUM251000 N
ENSPSIG00000006176 Pelodiscus sinensis ENSPSIG00000006176 I
ENSPSIG00000017283 Pelodiscus sinensis ENSPSIG00000017283 N
PPAI001408 Phlebotomus papatasi PPAI001408 I
ENSPFOG00000003170 Poecilia formosa ENSPFOG00000003170 I
ENSPFOG00000009547 Poecilia formosa ENSPFOG00000009547 I
ENSPFOG00000011847 Poecilia formosa ENSPFOG00000011847 N
ENSPFOG00000012196 Poecilia formosa ENSPFOG00000012196 N
ENSPFOG00000013997 Poecilia formosa ENSPFOG00000013997 I
Pvit_04865 Pogona vitticeps Pvit_04865 I
Pvit_05988 Pogona vitticeps Pvit_05988 I
ENSPPYG00000003475 Pongo abelii ENSPPYG00000003475 I
ENSPPYG00000010243 Pongo abelii ENSPPYG00000010243 I
ENSPPYG00000016530 Pongo abelii ENSPPYG00000016530 I
Ppa-egl-44 Pristionchus pacificus PPA23431 N
TEAD2 Procavia capensis ENSPCAG00000003576 I
TEAD3 Procavia capensis ENSPCAG00000010213 I
TEAD1 Procavia capensis ENSPCAG00000013657 I
TEAD4 Procavia capensis ENSPCAG00000013738 I
TEAD1 Pteropus vampyrus ENSPVAG00000001503 I
TEAD3 Pteropus vampyrus ENSPVAG00000002764 I
TEAD2 Pteropus vampyrus ENSPVAG00000010945 I
TEAD4 Pteropus vampyrus ENSPVAG00000013230 I
Tead1 Rattus norvegicus ENSRNOG00000015488 I
Tead2 Rattus norvegicus ENSRNOG00000020695 I
RSKR_0000765700 Rhabditophanes kr3021 RSKR_0000765700 N
Sakowv30030097m.g Saccoglossus kowalevskii Sakowv30030097m.g N
ENSSHAG00000011218 Sarcophilus harrisii ENSSHAG00000011218 I
ENSSHAG00000012780 Sarcophilus harrisii ENSSHAG00000012780 I
A_05340 Schistosoma haematobium A_05340 I
Sjc_0026250 Schistosoma japonicum Sjc_0026250 N
Smp_066050 Schistosoma mansoni Smp_066050 N
SMU15001290 Schmidtea mediterranea SMU15001290 N
SMU15036748 Schmidtea mediterranea SMU15036748 N
ENSSARG00000008050 Sorex araneus ENSSARG00000008050 N
TEAD3 Sorex araneus ENSSARG00000008305 I
L889_g27469 Steinernema feltiae L889_g27469 N
L893_g28603 Steinernema glaseri L893_g28603 N
L898_g3313 Steinernema monticolum L898_g3313 N
L892_g28430 Steinernema scapterisci L892_g28430 N
SPAL_0001147900 Strongyloides papillosus SPAL_0001147900 N
SPAL_0001402900 Strongyloides papillosus SPAL_0001402900 N
SSTP_0001098000 Strongyloides stercoralis SSTP_0001098000 N
SVE_1986900 Strongyloides venezuelensis SVE_1986900 N
TEAD4 Sus scrofa ENSSSCG00000000736 I
TEAD3 Sus scrofa ENSSSCG00000001544 I
TEAD2 Sus scrofa ENSSSCG00000025568 I
TsM_000210300 Taenia solium TsM_000210300 I
TEAD3 Taeniopygia guttata ENSTGUG00000001691 I
TEAD4 Taeniopygia guttata ENSTGUG00000013161 N
TEAD1 Taeniopygia guttata ENSTGUG00000015995 N
tead1a Takifugu rubripes ENSTRUG00000005940 I
tead3a Takifugu rubripes ENSTRUG00000011546 I
TEAD4 Takifugu rubripes ENSTRUG00000016489 I
tead1b Takifugu rubripes ENSTRUG00000017473 N
tead3b Takifugu rubripes ENSTRUG00000018177 I
ENSTSYG00000001514 Tarsius syrichta ENSTSYG00000001514 N
ENSTSYG00000006048 Tarsius syrichta ENSTSYG00000006048 I
tetur34g00910 Tetranychus urticae tetur34g00910 I
TEAD4 Tetraodon nigroviridis ENSTNIG00000003414 N
tead1a Tetraodon nigroviridis ENSTNIG00000008857 I
tead1b Tetraodon nigroviridis ENSTNIG00000009360 N
tead3b Tetraodon nigroviridis ENSTNIG00000018296 N
TMUE_s0021001300 Trichuris muris TMUE_s0021001300 N
TEAD1 Tursiops truncatus ENSTTRG00000006621 N
TEAD4 Tursiops truncatus ENSTTRG00000007774 N
TEAD3 Tursiops truncatus ENSTTRG00000009434 I
TEAD1 Vicugna pacos ENSVPAG00000005288 N
ENSVPAG00000012068 Vicugna pacos ENSVPAG00000012068 N
WUBG_04000 Wuchereria bancrofti WUBG_04000 N
tead4.S Xenopus laevis XB-GENE-956372 N
tead1 Xenopus tropicalis XB-GENE-5909149 I
tead4 Xenopus tropicalis XB-GENE-956369 I
XP_002943057 Xenopus tropicalis XP_002943057 I
ENSXMAG00000003088 Xiphophorus maculatus ENSXMAG00000003088 N
ENSXMAG00000007292 Xiphophorus maculatus ENSXMAG00000007292 N
ENSXMAG00000008189 Xiphophorus maculatus ENSXMAG00000008189 I
ENSXMAG00000015423 Xiphophorus maculatus ENSXMAG00000015423 I
ENSXMAG00000018099 Xiphophorus maculatus ENSXMAG00000018099 N
L798_06691 Zootermopsis nevadensis L798_06691 N