SMAD5 (Homo sapiens)
SMAD

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF03165 (MH1) IPR003619 ENSG00000113658 T324623_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
SMAD5
M05743_2.00		 Homo sapiens
YGTCTAGACW
WGTCTAGACR		 SELEX
Yin et al.(2017)
SMAD5_eDBD_HT-SELEX		 (Direct) (Direct)
SMAD5
M05744_2.00		 Homo sapiens
CGTCTAGACR
YGTCTAGACG		 SELEX
Yin et al.(2017)
SMAD5_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)
SMAD5
M11271_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD5_02		 (Direct) (Direct)
SMAD5
M11272_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD5_Q5_01		 (Direct) (Direct)
SMAD5
M11273_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD5_Q5		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Smad5
M11288_2.00 		Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD5_01 		1.000 1.000
Smad5
M11292_2.00 		Rattus norvegicus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD5_03 		1.000 1.000
SMAD1
M11286_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD1_01 		0.961 0.961
SMAD1
M11287_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD1_Q6 		0.959 0.959
SMAD9
M11274_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD8_01 		0.939 0.939
Smad9
M11290_2.00 		Rattus norvegicus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD8_02 		0.939 0.939
Smad9
M11289_2.00 		Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD8_03 		0.939 0.939
Mad
M06446_2.00 		Drosophila melanogaster
GYGHCGBCVS
SBGVCGDCRC		 B1H
Zhu et al.(2011)
Mad_FlyReg_FBgn0011648 		0.888 0.888
Mad
M08427_2.00 		Drosophila melanogaster
SNGRCGMSRVSRBNS
SNVYSBYSKCGYCNS		 ChIP-chip
Mathelier et al.(2014)
MA0535.1 		0.892 0.892
Mad
M09692_2.00 		Drosophila melanogaster
KCBGSHGKCGCSNC
GNSGCGMCDSCVGM		 Misc
Kulakovskiy et al.(2009)
Mad 		0.892 0.892
Mad
M11293_2.00 		Drosophila melanogaster Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
I$MAD_Q6 		0.892 0.892
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000422954 SMAD 31 80
ENSP00000424279 SMAD 31 132
ENSP00000425749 SMAD 31 128
ENSP00000441954 SMAD 31 132
ENSP00000446474 SMAD 31 132

Links

Other SMAD family TFs
Other Homo sapiens TFs

427 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ANAC004 Arabidopsis lyrata Al_scaffold_0001_137 I
anac005 Arabidopsis lyrata fgenesh1_pg.C_scaffold_1000123 I
anac048 Arabidopsis lyrata fgenesh1_pm.C_scaffold_1000114 I
NAC004 Arabidopsis thaliana AT1G02230 D
anac048 Arabidopsis thaliana AT3G04420 I
Bostr.5325s0016 Boechera stricta Bostr.5325s0016 I
Bostr.8819s0187 Boechera stricta Bostr.8819s0187 I
Bo5g002950 Brassica oleracea Bo5g002950 I
Bra033306 Brassica rapa Bra033306 I
Cagra.1968s0041 Capsella grandiflora Cagra.1968s0041 I