CIS-BP Database: Catalog of Inferred Sequence Binding Preferences

TF Information

TBX5 *(Sus scrofa)* T-box
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF00907 (T-box)	IPR001699	ENSSSCG00000009867	T340468_2.00	Ensembl (2018-Dec-8)	Link out
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
Tbx5 M00833_2.00	Mus musculus	AGGTGTBA	TVACACCT	PBM Weirauch et al.(2013) pTH3775	0.920	1.000
TBX5 M03552_2.00	Homo sapiens	AGGTGTBA	TVACACCT	SELEX Jolma et al.(2013) TBX5_1	0.920	1.000
TBX5 M03553_2.00	Homo sapiens	AGGTGTKANWWNTVACACCT	AGGTGTBANWWNTMACACCT	SELEX Jolma et al.(2013) TBX5_2	0.920	1.000
Tbx5 M09649_2.00	Mus musculus	AGGTGHBA	TVDCACCT	Misc Heinz et al.(2010) HL1-Tbx5.biotin_GSE21529	0.920	1.000
TBX5 M11374_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$TBX5_01	0.920	1.000
TBX5 M11375_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$TBX5_02	0.920	1.000
Tbx5 M11387_2.00	Mus musculus	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$TBX5_05	0.920	1.000
TBX5 M11376_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$TBX5_Q2	0.920	1.000
TBX5 M11377_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$TBX5_Q5	0.920	1.000
Tbx4 M00831_2.00	Mus musculus	AGGTGTBA	TVACACCT	PBM Weirauch et al.(2013) pTH3973	0.899	0.934
TBX4 M03558_2.00	Homo sapiens	AGGTGTBA	TVACACCT	SELEX Jolma et al.(2013) TBX4_1	0.899	0.934
TBX4 M03559_2.00	Homo sapiens	AGGTGTBANWWNTVACACBT	AVGTGTBANWWNTVACACCT	SELEX Jolma et al.(2013) TBX4_2	0.899	0.934
XP_008203914.1 M01029_2.00	Nasonia vitripennis	AGGTGTBA	TVACACCT	PBM SebePedros et al.(2013) pTH9336	0.804	0.615
Tbx2 M00830_2.00	Mus musculus	NYVDCACBHN	NDVGTGHBRN	PBM Weirauch et al.(2013) pTH3751	0.799	0.654
TBX2 M03556_2.00	Homo sapiens	GGTGTKADDWNTVACACB	VGTGTBANWHHTMACACC	SELEX Jolma et al.(2013) TBX2_1	0.799	0.654
TBX2 M03557_2.00	Homo sapiens	NAGGTGTBAWN	NWTVACACCTN	SELEX Jolma et al.(2013) TBX2_2	0.799	0.654
TBX2 M05799_2.00	Homo sapiens	NNVRCRCNNN	NNNGYGYBNN	SELEX Yin et al.(2017) TBX2_eDBD_HT-SELEX	0.799	0.654
Tbx2 M08044_2.00	Mus musculus	GCHYBCTGGGADHTGTAGTYH	DRACTACADHTCCCAGVRDGC	ChIP-seq Chen et al.(2011) SRP001585_Tbx2	0.799	0.654
TBX2 M11381_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$TBX2_Q2	0.799	0.654
TBX2 M11382_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$TBX2_Q5	0.799	0.654
TBX2 M05800_2.00	Homo sapiens	NNVRCRCBNN	NNVGYGYBNN	SELEX Yin et al.(2017) TBX2_eDBD_Methyl-HT-SELEX	0.799	0.654
Tbx3 M00834_2.00	Mus musculus	NHNDCACNHN	NDNGTGHNDN	PBM Weirauch et al.(2013) pTH3998	0.797	0.637
TBX3 M05801_2.00	Homo sapiens	NDSGTGTBRN	NYVACACSHN	SELEX Yin et al.(2017) TBX3_eDBD_HT-SELEX	0.797	0.637
TBX3 M09426_2.00	Homo sapiens	DVDGGTGBNAR	YTNVCACCHBH	Misc Kulakovskiy et al.(2013) TBX3_HUMAN.H11MO.0.C	0.797	0.637
Tbx3 M09429_2.00	Mus musculus	RRGGTGBBR	YVVCACCYY	Misc Kulakovskiy et al.(2013) TBX3_MOUSE.H11MO.0.B	0.797	0.637
TBX3 M05802_2.00	Homo sapiens	DAGGTGTKAN	NTMACACCTH	SELEX Yin et al.(2017) TBX3_eDBD_Methyl-HT-SELEX	0.797	0.637
XP_001195863 M02498_2.00	Strongylocentrotus purpuratus	AGGTGTBA	TVACACCT	PBM Weirauch et al.(2014) pTH9340	0.793	0.692
estExt_fgenesh2_pg.C_1570024 M01030_2.00	Branchiostoma floridae	NHNDCACNHN	NDNGTGHNDN	PBM SebePedros et al.(2013) pTH9244	0.787	0.681
TBX2 M02495_2.00	Gasterosteus aculeatus	NNVDCACNHN	NDNGTGHBNN	PBM Weirauch et al.(2014) pTH9182	0.767	0.637
TBX2 M02496_2.00	Takifugu rubripes	DAGGTGTBRN	NYVACACCTH	PBM Weirauch et al.(2014) pTH9289	0.767	0.632
Tbx20 M00835_2.00	Mus musculus	NRRGTGTBAN	NTVACACYYN	PBM Weirauch et al.(2013) pTH3777	0.754	0.610
TBX20 M03565_2.00	Homo sapiens	AGGTGTKARVGYGTGA	TCACRCBYTMACACCT	SELEX Jolma et al.(2013) TBX20_1	0.754	0.610
TBX20 M03566_2.00	Homo sapiens	AGGTGTGAAWDTSACACBT	AVGTGTSAHWTTCACACCT	SELEX Jolma et al.(2013) TBX20_2	0.754	0.610
TBX20 M03567_2.00	Homo sapiens	NNNDAGGTGTGAAND	HNTTCACACCTHNNN	SELEX Jolma et al.(2013) TBX20_3	0.754	0.610
TBX20 M03568_2.00	Homo sapiens	DAGGTGTGAWR	YWTCACACCTH	SELEX Jolma et al.(2013) TBX20_4	0.754	0.610
TBX20 M03569_2.00	Homo sapiens	AGGTGTKANGKTGTSA	TSACAMCNTMACACCT	SELEX Jolma et al.(2013) TBX20_5	0.754	0.610
TBX20 M05813_2.00	Homo sapiens	DAGGTGTKARSGTGTGAA	TTCACACSYTMACACCTH	SELEX Yin et al.(2017) TBX20_eDBD_HT-SELEX_1	0.754	0.610
TBX20 M05814_2.00	Homo sapiens	NAGGTGTGAAWTTCACACCTN	NAGGTGTGAAWTTCACACCTN	SELEX Yin et al.(2017) TBX20_eDBD_HT-SELEX_2	0.754	0.610
TBX20 M05817_2.00	Homo sapiens	DRRGTGTBADVGYGTBAN	NTVACRCBHTVACACYYH	SELEX Yin et al.(2017) TBX20_FL_HT-SELEX_1	0.754	0.610
TBX20 M05818_2.00	Homo sapiens	WTCACACYTAGGTGTKAM	KTMACACCTARGTGTGAW	SELEX Yin et al.(2017) TBX20_FL_HT-SELEX_2	0.754	0.610
Tbx20 M09430_2.00	Mus musculus	NDSTGNTGACAGSN	NSCTGTCANCASHN	Misc Kulakovskiy et al.(2013) TBX20_MOUSE.H11MO.0.C	0.754	0.610
Tbx20 M09650_2.00	Mus musculus	SCTGTCADCASN	NSTGHTGACAGS	Misc Heinz et al.(2010) Heart-Tbx20_GSE29636	0.754	0.610
TBX20 M11385_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$TBX20_05	0.754	0.610
TBX20 M05815_2.00	Homo sapiens	DAGGTGTKAASGYGTKAA	TTMACRCSTTMACACCTH	SELEX Yin et al.(2017) TBX20_eDBD_Methyl-HT-SELEX_1	0.754	0.610
TBX20 M05816_2.00	Homo sapiens	DASGTGTGAWWWTCACACCTH	DAGGTGTGAWWWTCACACSTH	SELEX Yin et al.(2017) TBX20_eDBD_Methyl-HT-SELEX_2	0.754	0.610
TBX20 M05819_2.00	Homo sapiens	DRGGYGTBARVGYGTKAN	NTMACRCBYTVACRCCYH	SELEX Yin et al.(2017) TBX20_FL_Methyl-HT-SELEX_1	0.754	0.610
TBX20 M05820_2.00	Homo sapiens	TTMACRCCTAVGTGTGAA	TTCACACBTAGGYGTKAA	SELEX Yin et al.(2017) TBX20_FL_Methyl-HT-SELEX_2	0.754	0.610
Eomes M00215_2.00	Mus musculus	RDGTGYBANN	NNTVRCACHY	PBM Badis et al.(2009) Eomes_0921	0.739	0.549
EOMES M03563_2.00	Homo sapiens	DAGGTGTGAWNNN	NNNWTCACACCTH	SELEX Jolma et al.(2013) EOMES_1	0.739	0.544
EOMES M03564_2.00	Homo sapiens	TVACACNTNNNDRNGTGTGA	TCACACNYHNNNANGTGTBA	SELEX Jolma et al.(2013) EOMES_2	0.739	0.544
EOMES M02752_2.00	Homo sapiens	AGGTGTGAW	WTCACACCT	SELEX Jolma et al.(2010) EOMES_monomer	0.739	0.544
EOMES M05807_2.00	Homo sapiens	DAGGTGTGAN	NTCACACCTH	SELEX Yin et al.(2017) EOMES_eDBD_HT-SELEX	0.739	0.544
EOMES M09647_2.00	Homo sapiens	ARGTGWKAAN	NTTMWCACYT	Misc Heinz et al.(2010) H9-Eomes_GSE26097	0.739	0.544
EOMES M05808_2.00	Homo sapiens	NABGTGYKAH	DTMRCACVTN	SELEX Yin et al.(2017) EOMES_eDBD_Methyl-HT-SELEX	0.739	0.544
For this family, TFs with SR scores > 0.734* will likely have a similar motif*

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
ENSSSCP00000010532	T-box	56	238	VFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRG

Links
Other T-box family TFs
Other *Sus scrofa* TFs

416 Related TFs

Name	Species	Gene ID	Motif Evidence	SR Score	Action

TBX5 (Sus scrofa) T-box

TF Information

Directly determined binding motifs

Motifs from related TFs

DNA Binding Domains

Links

416 Related TFs

TBX5 **(Sus scrofa)
T-box**