snap_masked-par_contig_44-abinit-gene-0.39 (Pythium arrhenomanes)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 snap_masked-par_contig_44-abinit-gene-0.39 T129274_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes an estrogen receptor and ligand-activated transcription factor. The canonical protein contains an N-terminal ligand-independent transactivation domain, a central DNA binding domain, a hinge domain, and a C-terminal ligand-dependent transactivation domain. The protein localizes to the nucleus where it may form either a homodimer or a heterodimer with estrogen receptor 2. The protein encoded by this gene regulates the transcription of many estrogen-inducible genes that play a role in growth, metabolism, sexual development, gestation, and other reproductive functions and is expressed in many non-reproductive tissues. The receptor encoded by this gene plays a key role in breast cancer, endometrial cancer, and osteoporosis. This gene is reported to have dozens of transcript variants due to the use of alternate promoters and alternative splicing, however, the full-length nature of many of these variants remain uncertain. [provided by RefSeq, Jul 2020]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
EPrPR00000013770 C2H2 ZF 29 54
EPrPR00000013770 C2H2 ZF 86 108
EPrPR00000013770 C2H2 ZF 162 184
EPrPR00000013770 C2H2 ZF 194 219
EPrPR00000013770 C2H2 ZF 227 252

Links

Other C2H2 ZF family TFs
Other Pythium arrhenomanes TFs

0 Related TFs

">No related TF found