HelroG173449 (Helobdella robusta)
Homeodomain,Paired box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox)
PF00292 (PAX) 		IPR001356
IPR001523 		HelroG173449 T237622_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
toy
M03899_2.00 		Drosophila melanogaster
TTYACGCWTGASTGMACAN
NTGTKCASTCAWGCGTRAA		 SELEX
Nitta et al.(2015)
toy_1 		0.835 0.835
toy
M03900_2.00 		Drosophila melanogaster
NTYACGCWTSAVTGMRCNN
NNGYKCABTSAWGCGTRAN		 SELEX
Nitta et al.(2015)
toy_2 		0.835 0.835
toy
M03901_2.00 		Drosophila melanogaster
VATTANBHAYGSWYSRN
NYSRWSCRTDVNTAATB		 SELEX
Nitta et al.(2015)
toy_3 		0.835 0.835
PAX6
M00342_2.00 		Homo sapiens
NNNRCDMATTANNN
NNNTAATKHGYNNN		 PBM
Barrera et al.(2016)
PAX6_REF 		0.824 0.824
Pax6
M00540_2.00 		Mus musculus
CBAATTAA
TTAATTVG		 PBM
Berger et al.(2008)
Pax6_3838 		0.824 0.824
PAX6
M03291_2.00 		Homo sapiens
DTWYACGCWTGANTGMDYH
DRHKCANTCAWGCGTRWAH		 SELEX
Jolma et al.(2013)
PAX6_1 		0.824 0.824
ey
M03896_2.00 		Drosophila melanogaster
CKAATTAD
HTAATTMG		 SELEX
Nitta et al.(2015)
ey_1 		0.824 0.824
ey
M03897_2.00 		Drosophila melanogaster
HTAATCKMATTAD
HTAATKMGATTAD		 SELEX
Nitta et al.(2015)
ey_2 		0.824 0.824
ey
M03898_2.00 		Drosophila melanogaster
WAAYYRRTTN
NAAYYRRTTW		 SELEX
Nitta et al.(2015)
ey_3 		0.824 0.824
PAX6
M05412_2.00 		Homo sapiens
NYACGCHYSRNYRMNYN
NRNKYRNYSRDGCGTRN		 SELEX
Yin et al.(2017)
PAX6_eDBD_HT-SELEX 		0.824 0.824
PAX6
M05414_2.00 		Homo sapiens
NYRCGCNYSRNYRVNYN
NRNBYRNYSRNGCGYRN		 SELEX
Yin et al.(2017)
PAX6_FL_HT-SELEX 		0.824 0.824
PAX6
M02689_2.00 		Homo sapiens
TTYACGCWTSANTK
MANTSAWGCGTRAA		 SELEX
Mathelier et al.(2014)
MA0069.1 		0.824 0.824
PAX6
M09216_2.00 		Homo sapiens
TYMYRCWTSRNT
ANYSAWGYRKRA		 Misc
Kulakovskiy et al.(2013)
PAX6_HUMAN.H11MO.0.C 		0.824 0.824
Pax6
M09217_2.00 		Mus musculus
TYMYRCWTSRNT
ANYSAWGYRKRA		 Misc
Kulakovskiy et al.(2013)
PAX6_MOUSE.H11MO.0.C 		0.824 0.824
PAX6
M10806_2.00 		Homo sapiens
NHNNTTYACGCWTSANTKVHH
DDBMANTSAWGCGTRAANNDN		 Transfac
Matys et al.(2006)
V$PAX6_01 		0.824 0.824
PAX6
M10807_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX6_Q2 		0.824 0.824
PAX6
M00339_2.00 		Homo sapiens
NNNNSGKVGGHNN
NNDCCBMCSNNNN		 PBM
Barrera et al.(2016)
PAX6_R128C 		0.824 0.824
PAX6
M00344_2.00 		Homo sapiens
NNMSASGBYNNN
NNNRVCSTSKNN		 PBM
Barrera et al.(2016)
PAX6_V126D 		0.824 0.824
PAX6
M05413_2.00 		Homo sapiens
DYRCGCWTSRNYRMNYN
NRNKYRNYSAWGCGYRH		 SELEX
Yin et al.(2017)
PAX6_eDBD_Methyl-HT-SELEX 		0.824 0.824
PAX6
M05415_2.00 		Homo sapiens
NYACGCHYSRNYRMHYN
NRDKYRNYSRDGCGTRN		 SELEX
Yin et al.(2017)
PAX6_FL_Methyl-HT-SELEX 		0.824 0.824
PAX6
M00335_2.00 		Homo sapiens
BRNNNNNN
NNNNNNYV		 PBM
Barrera et al.(2016)
PAX6_A79E 		0.818 0.818
PAX6
M00336_2.00 		Homo sapiens
RTGCACAC
GTGTGCAY		 PBM
Barrera et al.(2016)
PAX6_F258S 		0.818 0.818
PAX6
M00337_2.00 		Homo sapiens
NMTAATTANNN
NNNTAATTAKN		 PBM
Barrera et al.(2016)
PAX6_P118R 		0.818 0.818
PAX6
M00338_2.00 		Homo sapiens
WSGVRVDR
YHBYBCSW		 PBM
Barrera et al.(2016)
PAX6_P68S 		0.818 0.818
PAX6
M00340_2.00 		Homo sapiens
NNNNNRN
NYNNNNN		 PBM
Barrera et al.(2016)
PAX6_R242T 		0.818 0.818
PAX6
M00341_2.00 		Homo sapiens
BTSCCCSGSC
GSCSGGGSAV		 PBM
Barrera et al.(2016)
PAX6_R26G 		0.818 0.818
PAX6
M00343_2.00 		Homo sapiens
NNNNCCCVKCNBN
NVNGMBGGGNNNN		 PBM
Barrera et al.(2016)
PAX6_S119R 		0.818 0.818
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
HelroP173449 Paired box 49 167
HelroP173449 Homeodomain 287 343

Links

Other Homeodomain,Paired box family TFs
Other Helobdella robusta TFs

180 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
PAX6 Sorex araneus ENSSARG00000011424 I 0.838
HelroG80374 Helobdella robusta HelroG80374 I 0.835
ENSONIG00000005541 Oreochromis niloticus ENSONIG00000005541 I 0.830
pax6b Gasterosteus aculeatus ENSGACG00000016030 I 0.830
Sakowv30026828m.g Saccoglossus kowalevskii Sakowv30026828m.g I 0.830
pax6b Oryzias latipes ENSORLG00000009913 I 0.830
TTRE_0000173501 Trichuris trichiura TTRE_0000173501 I 0.830
pax6a Danio rerio ENSDARG00000103379 I 0.830
ENSPFOG00000016987 Poecilia formosa ENSPFOG00000016987 I 0.830
PAX6 Echinops telfairi ENSETEG00000002655 I 0.827
ENSLACG00000015337 Latimeria chalumnae ENSLACG00000015337 I 0.824
ENSLOCG00000004578 Lepisosteus oculatus ENSLOCG00000004578 I 0.824
PAX6 Tupaia belangeri ENSTBEG00000004748 I 0.824
Alligator_sinensis_CCG012954.1 Alligator sinensis Alligator_sinensis_CCG012954.1 I 0.824
ENSGMOG00000012304 Gadus morhua ENSGMOG00000012304 I 0.824
PAX6 Monodelphis domestica ENSMODG00000009611 I 0.824
pax6.S Xenopus laevis XB-GENE-6464331 I 0.824
ACYPI008177 Acyrthosiphon pisum ACYPI008177 I 0.824
GF21877 Drosophila ananassae FBgn0098877 I 0.824
ey Drosophila melanogaster FBgn0005558 D 0.824
L798_00712 Zootermopsis nevadensis L798_00712 I 0.824
pax6b Danio rerio ENSDARG00000045936 I 0.824
ENSAMXG00000001228 Astyanax mexicanus ENSAMXG00000001228 I 0.819
ENSORLG00000000847 Oryzias latipes ENSORLG00000000847 I 0.818
PAX6 Homo sapiens ENSG00000007372 D 0.818
TC007409 Tribolium castaneum TC007409 I 0.818
ENSONIG00000004074 Oreochromis niloticus ENSONIG00000004074 I 0.818
ENSGACG00000002490 Gasterosteus aculeatus ENSGACG00000002490 I 0.818
pax6.L Xenopus laevis XB-GENE-865046 I 0.818
ENSGMOG00000019087 Gadus morhua ENSGMOG00000019087 I 0.813
GM13021 Drosophila sechellia FBgn0167952 I 0.808
GE14563 Drosophila yakuba FBgn0232162 I 0.808
D918_01592 Trichuris suis D918_01592 I 0.808
pax6b Tetraodon nigroviridis ENSTNIG00000013804 I 0.808
ENSXMAG00000014260 Xiphophorus maculatus ENSXMAG00000014260 I 0.808
toy Drosophila melanogaster FBgn0019650 D 0.808
GG16402 Drosophila erecta FBgn0108634 I 0.808
PAX6 Felis catus ENSFCAG00000007094 I 0.802
GI14042 Drosophila mojavensis FBgn0136796 I 0.802
GA27636 Drosophila pseudoobscura FBgn0249001 I 0.802
GK13683 Drosophila willistoni FBgn0215691 I 0.802
PAX6 Otolemur garnettii ENSOGAG00000007857 I 0.802
PAX6 Equus caballus ENSECAG00000021000 I 0.802
ENSPSIG00000012748 Pelodiscus sinensis ENSPSIG00000012748 I 0.802
pax6b Takifugu rubripes ENSTRUG00000006935 I 0.802
NV17076 Nasonia vitripennis NV17076 I 0.802
TMUE_s0038005250 Trichuris muris TMUE_s0038005250 I 0.802
Pax6 Rattus norvegicus ENSRNOG00000004410 I 0.802
CGI_10027695 Crassostrea gigas CGI_10027695 I 0.802
ACYPI067710 Acyrthosiphon pisum ACYPI067710 I 0.802
PAX6 Oryctolagus cuniculus ENSOCUG00000011075 I 0.802
PAX6 Loxodonta africana ENSLAFG00000015520 I 0.802
GB41504 Apis mellifera GB41504 I 0.802
Cflo_00481--XP_394648.3_APIME Camponotus floridanus Cflo_00481--XP_394648.3_APIME I 0.802
ENSAMEG00000006908 Ailuropoda melanoleuca ENSAMEG00000006908 I 0.802
GL17563 Drosophila persimilis FBgn0155166 I 0.802
PAX6 Gorilla gorilla ENSGGOG00000010246 I 0.802
ENSAMXG00000013008 Astyanax mexicanus ENSAMXG00000013008 I 0.802
GJ13300 Drosophila virilis FBgn0200526 I 0.802
ENSP00000368401-D1 Bos grunniens ENSP00000368401-D1 I 0.802
ENSNLEG00000017888 Nomascus leucogenys ENSNLEG00000017888 I 0.802
Hsal_09597--XP_394648.3_APIME Harpegnathos saltator Hsal_09597--XP_394648.3_APIME I 0.802
GH23963 Drosophila grimshawi FBgn0131420 I 0.802
ENSP00000368424 Macaca fascicularis ENSP00000368424 I 0.802
PAX6 Cavia porcellus ENSCPOG00000007245 I 0.802
GB50342 Apis mellifera GB50342 I 0.797
ENSXMAG00000016421 Xiphophorus maculatus ENSXMAG00000016421 I 0.797
ENSTRUG00000017375 Takifugu rubripes ENSTRUG00000017375 I 0.797
NV15820 Nasonia vitripennis NV15820 I 0.797
ENSMPUG00000011295 Mustela putorius furo ENSMPUG00000011295 I 0.797
TC008176 Tribolium castaneum TC008176 I 0.797
ENSCSAG00000005253 Chlorocebus sabaeus ENSCSAG00000005253 I 0.797
PAX6 Dasypus novemcinctus ENSDNOG00000000761 I 0.797
PAX6 Gallus gallus ENSGALG00000012123 I 0.797
PAX6 Microcebus murinus ENSMICG00000004089 I 0.797
PAX6 Callithrix jacchus ENSCJAG00000005942 I 0.797
PAX6 Bos taurus ENSBTAG00000004561 I 0.797
pax6 Xenopus tropicalis XB-GENE-484088 I 0.797
SMU15027897 Schmidtea mediterranea SMU15027897 I 0.797
Pvit_09512 Pogona vitticeps Pvit_09512 I 0.797
PAX6 Anolis carolinensis ENSACAG00000002252 I 0.797
PAX6 Myotis lucifugus ENSMLUG00000006517 I 0.797
PAX6 Macaca mulatta ENSMMUG00000016810 I 0.797
PAX6 Procavia capensis ENSPCAG00000005165 I 0.797
ENSPANG00000005448 Papio anubis ENSPANG00000005448 I 0.797
PHUM097050 Pediculus humanus PHUM097050 I 0.797
ENSSHAG00000016310 Sarcophilus harrisii ENSSHAG00000016310 I 0.797
PAX6 Sus scrofa ENSSSCG00000013320 I 0.797
ENSSTOG00000003211 Ictidomys tridecemlineatus ENSSTOG00000003211 I 0.797
PAX6 Ochotona princeps ENSOPRG00000001678 I 0.797
Pax6 Mus musculus ENSMUSG00000027168 D 0.797
ENSOARG00000016191 Ovis aries ENSOARG00000016191 I 0.797
L798_11483 Zootermopsis nevadensis L798_11483 I 0.796
GD24416 Drosophila simulans FBgn0195753 I 0.795
MCINX016249 Melitaea cinxia MCINX016249 I 0.795
LotgiG133720 Lottia gigantea LotgiG133720 I 0.791
GI14081 Drosophila mojavensis FBgn0136835 I 0.791
GE14559 Drosophila yakuba FBgn0232158 I 0.791
ey Drosophila virilis FBgn0028754 I 0.791
ey Drosophila sechellia FBgn0068720 I 0.791
ey Drosophila pseudoobscura FBgn0018538 I 0.791
GG16399 Drosophila erecta FBgn0108631 I 0.791
GK13702 Drosophila willistoni FBgn0215710 I 0.791
DAPPUDRAFT_249978 Daphnia pulex DAPPUDRAFT_249978 I 0.791
ey Drosophila persimilis FBgn0043659 I 0.791
SMAR013763 Strigamia maritima SMAR013763 I 0.786
DAPPUDRAFT_249991 Daphnia pulex DAPPUDRAFT_249991 I 0.786
ENSTNIG00000002471 Tetraodon nigroviridis ENSTNIG00000002471 I 0.786
GF22818 Drosophila ananassae FBgn0099812 I 0.786
ACUA021227 Anopheles culicifacies ACUA021227 I 0.784
D915_07175 Fasciola hepatica D915_07175 I 0.784
AAEL002321 Aedes aegypti AAEL002321 I 0.784
ENSCSAVG00000007987 Ciona savignyi ENSCSAVG00000007987 I 0.783
Cmyd_10016391 Chelonia mydas Cmyd_10016391 I 0.782
ENSCING00000006503 Ciona intestinalis ENSCING00000006503 I 0.780
T265_14971 Opisthorchis viverrini T265_14971 I 0.780
ISCW021772 Ixodes scapularis ISCW021772 I 0.779
L596_g12356 Steinernema carpocapsae L596_g12356 I 0.775
L892_g3713 Steinernema scapterisci L892_g3713 I 0.775
ENSPPYG00000003386 Pongo abelii ENSPPYG00000003386 I 0.772
CRE07226 Caenorhabditis remanei CRE07226 I 0.769
CBN04513 Caenorhabditis brenneri CBN04513 I 0.769
Smp_170750 Schistosoma mansoni Smp_170750 I 0.767
AMIN002132 Anopheles minimus AMIN002132 I 0.766
AATE014626 Anopheles atroparvus AATE014626 I 0.766
ADIR000973 Anopheles dirus ADIR000973 I 0.766
ACHR009845 Anopheles christyi ACHR009845 I 0.766
ASTEI06205 Anopheles stephensi ASTEI06205 I 0.766
AFUN011570 Anopheles funestus AFUN011570 I 0.766
ISCW006352 Ixodes scapularis ISCW006352 I 0.764
T265_09221 Opisthorchis viverrini T265_09221 I 0.764
ADAC001560 Anopheles darlingi ADAC001560 I 0.763
AMEC013051 Anopheles melas AMEC013051 I 0.762
AFAF017899 Anopheles farauti AFAF017899 I 0.762
AEPI005798 Anopheles epiroticus AEPI005798 I 0.762
AMEM002691 Anopheles merus AMEM002691 I 0.762
AGAP000067 Anopheles gambiae AGAP000067 I 0.762
AQUA008313 Anopheles quadriannulatus AQUA008313 I 0.762
AARA001110 Anopheles arabiensis AARA001110 I 0.762
csin110224 Clonorchis sinensis csin110224 I 0.760
AMIN002127 Anopheles minimus AMIN002127 I 0.758
PTRK_0000512100 Parastrongyloides trichosuri PTRK_0000512100 I 0.758
ASTEI06200 Anopheles stephensi ASTEI06200 I 0.758
AQUA008308 Anopheles quadriannulatus AQUA008308 I 0.758
AEPI005803 Anopheles epiroticus AEPI005803 I 0.758
ASIS012967 Anopheles sinensis ASIS012967 I 0.758
AGAP000063 Anopheles gambiae AGAP000063 I 0.758
AARA001115 Anopheles arabiensis AARA001115 I 0.758
AALB006354 Anopheles albimanus AALB006354 I 0.758
CpipJ_CPIJ006390 Culex pipiens CpipJ_CPIJ006390 I 0.756
Ogr12767 Ophisaurus gracilis Ogr12767 I 0.756
CPIJ006390 Culex quinquefasciatus CPIJ006390 I 0.756
RSKR_0000862000 Rhabditophanes kr3021 RSKR_0000862000 I 0.753
AMEC021831 Anopheles melas AMEC021831 I 0.753
tetur09g00660 Tetranychus urticae tetur09g00660 I 0.753
vab-3 Caenorhabditis elegans WBGene00006870 I 0.753
AFUN011575 Anopheles funestus AFUN011575 I 0.753
AALB006643 Anopheles albimanus AALB006643 I 0.750
EFV57892 Trichinella spiralis EFV57892 I 0.750
ACUA016154 Anopheles culicifacies ACUA016154 I 0.750
SSTP_0001059400 Strongyloides stercoralis SSTP_0001059400 I 0.747
SPAL_0001466800 Strongyloides papillosus SPAL_0001466800 I 0.747
Smp_160670 Schistosoma mansoni Smp_160670 I 0.747
SMTD_0000837201 Schistosoma mattheei SMTD_0000837201 I 0.747
A_05170 Schistosoma haematobium A_05170 I 0.747
SVE_0819200 Strongyloides venezuelensis SVE_0819200 I 0.747
ENSTSYG00000011965 Tarsius syrichta ENSTSYG00000011965 I 0.746
CpipJ_CPIJ006398 Culex pipiens CpipJ_CPIJ006398 I 0.744
CPIJ006398 Culex quinquefasciatus CPIJ006398 I 0.744
BXY_1643500 Bursaphelenchus xylophilus BXY_1643500 I 0.744
ADAC003449 Anopheles darlingi ADAC003449 I 0.743
AFAF009619 Anopheles farauti AFAF009619 I 0.743
ACHR008920 Anopheles christyi ACHR008920 I 0.741
csin101119 Clonorchis sinensis csin101119 I 0.739
ASIS012617 Anopheles sinensis ASIS012617 I 0.735
Afo_R014630 Aptenodytes forsteri Afo_R014630 I 0.734
MCOS_0000220101 Mesocestoides corti MCOS_0000220101 I 0.731
D917_00854 Trichinella nativa D917_00854 I 0.720
PAX6 Ornithorhynchus anatinus ENSOANG00000015149 I 0.709
fgenesh2_pg.scaffold_199000043 Branchiostoma floridae fgenesh2_pg.scaffold_199000043 I 0.701