| NCBI Gene Info:Predicted to enable histone methyltransferase activity (H3-K9 specific). Involved in several processes, including histone lysine methylation; negative regulation of vulval development; and regulation of gene expression. Located in cytoplasm. Is expressed in several structures, including germ line; hypodermis; intestine; muscle cell; and neurons. Human ortholog(s) of this gene implicated in autistic disorder and lung cancer. Orthologous to human SETDB1 (SET domain bifurcated histone lysine methyltransferase 1) and SETDB2 (SET domain bifurcated histone lysine methyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022] |