NCBI Gene Info:Enables sequence-specific DNA binding activity. Involved in cell fate specification; pharyngeal muscle development; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in several structures, including MS; MSa; MSaa; MSap; and MSp. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human TBR1 (T-box brain transcription factor 1) and EOMES (eomesodermin). [provided by Alliance of Genome Resources, Apr 2022] |