HOXD1 (Homo sapiens)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSG00000128645 T093295_1.02 Ensembl (2011-Oct-26) Link out
NCBI Gene Info:
This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. This nuclear protein functions as a sequence-specific transcription factor that is involved in differentiation and limb development. Mutations in this gene have been associated with severe developmental defects on the anterior-posterior (a-p) limb axis. [provided by RefSeq, Jul 2008]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID DBD
Identity
Hoxd1
M1025_1.02
Mus musculus
NNHNATYN

NRATNDNN
PBM
Berger et al.(2008)
Hoxd1_3448
0.982
HOXA1
M6291_1.02
Homo sapiens
CATCCATCMN

NKGATGGATG
HocoMoco
Kulakovskiy et al.(2013)
HXA1_f1
0.860
HOXA1
M5533_1.02
Homo sapiens
NNTAATTRNN

NNYAATTANN
SELEX
Jolma et al.(2013)
HOXA1_1
0.860
Hoxa1
M0982_1.02
Mus musculus
NHRATKRNN

NNYMATYDN
PBM
Berger et al.(2008)
Hoxa1_3425
0.860
labial
M1164_1.02
Cupiennius salei
VTAATTAA

TTAATTAB
PBM
Weirauch et al.(2014)
pTH6251
0.857
lab
M5068_1.02
Drosophila melanogaster
YTAATKA

TMATTAR
B1H
Zhu et al.(2011)
Lab_SOLEXA_FBgn0002522
0.842
lab
M5067_1.02
Drosophila melanogaster
TTAATKA

TMATTAA
B1H
Zhu et al.(2011)
Lab_Cell_FBgn0002522
0.842
lab
M2038_1.02
Drosophila melanogaster
TTAATKA

TMATTAA
B1H
Mathelier et al.(2014)
MA0230.1
0.842
HOXB1
M6295_1.02
Homo sapiens
CCATCMATCW

WGATKGATGG
HocoMoco
Kulakovskiy et al.(2013)
HXB1_f1
0.821
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000328598 Homeodomain 231 286
ENSP00000387231 Homeodomain 63 118

Links

Other Homeodomain family TFs
Other Homo sapiens TFs

0 Related TFs

">No related TF found