Pou6f1 (Mus musculus)
Homeodomain,POU

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox)
PF00157 (Pou) 		IPR001356
IPR000327 		ENSMUSG00000009739 T238376_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including genitourinary system; limb; nervous system; sensory organ; and skeletal musculature. Orthologous to human POU6F1 (POU class 6 homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Pou6f1
M00545_2.00		 Mus musculus
NNNTMATTAN
NTAATKANNN		 PBM
Berger et al.(2008)
Pou6f1_1731		 (Direct) (Direct)
Pou6f1
M00546_2.00		 Mus musculus
NNNTMATTAN
NTAATKANNN		 PBM
Berger et al.(2008)
Pou6f1_3733		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.993 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00545_2.00 POU 19 90
M00545_2.00 Homeodomain 112 168
M00546_2.00 POU 19 90
M00546_2.00 Homeodomain 112 168

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000073504 POU 417 488
ENSMUSP00000073504 Homeodomain 510 566

Links

Other Homeodomain,POU family TFs
Other Mus musculus TFs

1 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSMUSG00000098598 Mus musculus ENSMUSG00000098598 I 1.000