Pou5f1 (Mus musculus)
Homeodomain,POU

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox)
PF00157 (Pou) 		IPR001356
IPR000327 		ENSMUSG00000024406 T238377_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
The protein encoded by this gene belongs to the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein plays a key role in embryonic development and stem cell pluripotency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Pou5f1
M08031_2.00		 Mus musculus
YYWTTNWHWTKBWAA
TTWVMAWDWNAAWRR		 ChIP-seq
Chen et al.(2011)
GSE11329_bioOct4		 (Direct) (Direct)
Pou5f1
M08032_2.00		 Mus musculus
BYWTTSWHATGCADA
THTGCATDWSAAWRV		 ChIP-seq
Chen et al.(2011)
SRP000217_Oct4		 (Direct) (Direct)
Pou5f1
M08033_2.00		 Mus musculus
YWTTSWNATGCWAAW
WTTWGCATNWSAAWR		 ChIP-seq
Chen et al.(2011)
SRP000712_Oct4		 (Direct) (Direct)
Pou5f1
M09225_2.00		 Mus musculus
BYWTTSWNATGCWAAW
WTTWGCATNWSAAWRV		 Misc
Kulakovskiy et al.(2013)
PO5F1_MOUSE.H11MO.0.A		 (Direct) (Direct)
Pou5f1
M10855_2.00		 Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$OCT4_01		 (Direct) (Direct)
Pou5f1
M10856_2.00		 Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$OCT4_02		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.993 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000025271 POU 134 205
ENSMUSP00000025271 Homeodomain 224 280
ENSMUSP00000133633 POU 3 74
ENSMUSP00000133633 Homeodomain 93 132
ENSMUSP00000134060 POU 3 74
ENSMUSP00000134060 Homeodomain 93 132
ENSMUSP00000134493 POU 28 99
ENSMUSP00000134493 Homeodomain 118 157
ENSMUSP00000134654 POU 3 74
ENSMUSP00000134654 Homeodomain 93 132
ENSMUSP00000134729 POU 3 74
ENSMUSP00000134729 Homeodomain 93 132

Links

Other Homeodomain,POU family TFs
Other Mus musculus TFs

1 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action