Afo_R003239 (Aptenodytes forsteri)
AP-2

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF03299 (TF_AP-2) IPR013854 Afo_R003239 T011149_2.00 GigaDB (2015-Oct-22)

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Tfap2a
M00111_2.00 		Mus musculus
HSCCBNVRGS
SCYBNVGGSD		 PBM
Badis et al.(2009)
Tcfap2a_2337 		0.861 0.861
TFAP2A
M02762_2.00 		Homo sapiens
HGCCYBVRGGSD
HSCCYBVRGGCD		 SELEX
Jolma et al.(2013)
TFAP2A_1 		0.861 0.861
TFAP2A
M02763_2.00 		Homo sapiens
HGCCYSMGGCN
NGCCKSRGGCD		 SELEX
Jolma et al.(2013)
TFAP2A_2 		0.861 0.861
TFAP2A
M02764_2.00 		Homo sapiens
NSCCCBNVRGGSN
NSCCYBNVGGGSN		 SELEX
Jolma et al.(2013)
TFAP2A_3 		0.861 0.861
TFAP2A
M02765_2.00 		Homo sapiens
HGCCTSRGGCD
HGCCYSAGGCD		 SELEX
Jolma et al.(2013)
TFAP2A_4 		0.861 0.861
TFAP2A
M02766_2.00 		Homo sapiens
HGCCYBVRGGCD
HGCCYBVRGGCD		 SELEX
Jolma et al.(2013)
TFAP2A_5 		0.861 0.861
TFAP2A
M02767_2.00 		Homo sapiens
WGCCCYNVGGGCD
HGCCCBNRGGGCW		 SELEX
Jolma et al.(2013)
TFAP2A_6 		0.861 0.861
Tfap2a
M02768_2.00 		Mus musculus
HGCCYBVRGGCR
YGCCYBVRGGCD		 SELEX
Jolma et al.(2013)
Tcfap2a_1 		0.861 0.861
Tfap2a
M02769_2.00 		Mus musculus
HGCCTSRGGCD
HGCCYSAGGCD		 SELEX
Jolma et al.(2013)
Tcfap2a_2 		0.861 0.861
Tfap2a
M02770_2.00 		Mus musculus
WGCCCYBVGGGCD
HGCCCBVRGGGCW		 SELEX
Jolma et al.(2013)
Tcfap2a_3 		0.861 0.861
TFAP2A
M04054_2.00 		Homo sapiens
NGCCBSVGGCN
NGCCBSVGGCN		 SELEX
Yin et al.(2017)
TFAP2A_FL_HT-SELEX 		0.861 0.861
TFAP2A
M07784_2.00 		Homo sapiens
NBNSCCYSRGGSCWN
NWGSCCYSRGGSNVN		 ChIP-seq
Gerstein et al.(2012)
HeLa-S3_AP2ALPHA_UCD 		0.861 0.861
TFAP2A
M08703_2.00 		Homo sapiens
NHDSCCYCAGGSHWN
NWDSCCTGRGGSHDN		 Misc
Kulakovskiy et al.(2013)
AP2A_HUMAN.H11MO.0.A 		0.861 0.861
Tfap2a
M08704_2.00 		Mus musculus
SCCYCRGGSNNN
NNNSCCYGRGGS		 Misc
Kulakovskiy et al.(2013)
AP2A_MOUSE.H11MO.0.A 		0.861 0.861
TFAP2A
M09755_2.00 		Homo sapiens
GCCBBVVGS
SCBBVVGGC		 Transfac
Matys et al.(2006)
V$AP2ALPHA_01 		0.861 0.861
TFAP2A
M09756_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AP2ALPHA_02 		0.861 0.861
TFAP2A
M09757_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AP2ALPHA_03 		0.861 0.861
TFAP2A
M09758_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AP2ALPHA_Q4 		0.861 0.861
TFAP2A
M09759_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AP2ALPHA_Q6 		0.861 0.861
TFAP2A
M09760_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TFAP2A_09 		0.861 0.861
TFAP2A
M04055_2.00 		Homo sapiens
NSCCTNAGGSN
NSCCTNAGGSN		 SELEX
Yin et al.(2017)
TFAP2A_FL_Methyl-HT-SELEX 		0.861 0.861
Tfap2c
M00113_2.00 		Mus musculus
NSCCBBVGGS
SCCBVVGGSN		 PBM
Badis et al.(2009)
Tcfap2c_2912 		0.851 0.851
Tfap2c
M08706_2.00 		Mus musculus
NNSCCYGRGGSNN
NNSCCYCRGGSNN		 Misc
Kulakovskiy et al.(2013)
AP2C_MOUSE.H11MO.0.A 		0.851 0.851
Tfap2b
M00112_2.00 		Mus musculus
CCBSRGGSNW
WNSCCYSVGG		 PBM
Badis et al.(2009)
Tcfap2b_3988 		0.840 0.840
TFAP2B
M02753_2.00 		Homo sapiens
HSCCYBVRGGCD
HGCCYBVRGGSD		 SELEX
Jolma et al.(2013)
TFAP2B_1 		0.840 0.840
TFAP2B
M02754_2.00 		Homo sapiens
HGCCTSRGGCD
HGCCYSAGGCD		 SELEX
Jolma et al.(2013)
TFAP2B_2 		0.840 0.840
TFAP2B
M02755_2.00 		Homo sapiens
WGCCCYBVRGGCD
HGCCYBVRGGGCW		 SELEX
Jolma et al.(2013)
TFAP2B_3 		0.840 0.840
TFAP2B
M04046_2.00 		Homo sapiens
NSCCBNVGGSN
NSCCBNVGGSN		 SELEX
Yin et al.(2017)
TFAP2B_eDBD_HT-SELEX 		0.840 0.840
TFAP2B
M08701_2.00 		Homo sapiens
GSCYGVGGRV
BYCCBCRGSC		 Misc
Kulakovskiy et al.(2013)
AP2B_HUMAN.H11MO.0.B 		0.840 0.840
Tfap2b
M08705_2.00 		Mus musculus
GSCYGVGGRV
BYCCBCRGSC		 Misc
Kulakovskiy et al.(2013)
AP2B_MOUSE.H11MO.0.B 		0.840 0.840
TFAP2B
M09750_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AP2BETA_Q3 		0.840 0.840
TFAP2B
M04047_2.00 		Homo sapiens
NSCCYNRGGSD
HSCCYNRGGSN		 SELEX
Yin et al.(2017)
TFAP2B_eDBD_Methyl-HT-SELEX 		0.840 0.840
TFAP2C
M02756_2.00 		Homo sapiens
HSCCYBVRGGCD
HGCCYBVRGGSD		 SELEX
Jolma et al.(2013)
TFAP2C_1 		0.835 0.835
TFAP2C
M02757_2.00 		Homo sapiens
HGCCTBRGGCD
HGCCYVAGGCD		 SELEX
Jolma et al.(2013)
TFAP2C_2 		0.835 0.835
TFAP2C
M02758_2.00 		Homo sapiens
WGCCCYNRGGGCD
HGCCCYNRGGGCW		 SELEX
Jolma et al.(2013)
TFAP2C_3 		0.835 0.835
TFAP2C
M02759_2.00 		Homo sapiens
HSCCYBVRGGCD
HGCCYBVRGGSD		 SELEX
Jolma et al.(2013)
TFAP2C_4 		0.835 0.835
TFAP2C
M02760_2.00 		Homo sapiens
NGCCCBNVRGGCN
NGCCYBNVGGGCN		 SELEX
Jolma et al.(2013)
TFAP2C_5 		0.835 0.835
TFAP2C
M02761_2.00 		Homo sapiens
HGCCTBRGGCD
HGCCYVAGGCD		 SELEX
Jolma et al.(2013)
TFAP2C_6 		0.835 0.835
TFAP2C
M04048_2.00 		Homo sapiens
NSCYHNHRGBN
NVCYDNDRGSN		 SELEX
Yin et al.(2017)
TFAP2C_eDBD_HT-SELEX 		0.835 0.835
TFAP2C
M07783_2.00 		Homo sapiens
NSCCYSRGGSCANDN
NHNTGSCCYSRGGSN		 ChIP-seq
Gerstein et al.(2012)
HeLa-S3_AP2GAMMA_UCD 		0.835 0.835
TFAP2C
M08702_2.00 		Homo sapiens
NDSCCYCAGGSHHN
NDDSCCTGRGGSHN		 Misc
Kulakovskiy et al.(2013)
AP2C_HUMAN.H11MO.0.A 		0.835 0.835
TFAP2C
M09451_2.00 		Homo sapiens
SCCYSRGGSHNN
NNDSCCYSRGGS		 Misc
Heinz et al.(2010)
MCF7-TFAP2C_GSE21234 		0.835 0.835
TFAP2C
M09751_2.00 		Homo sapiens
GCCBBVRGS
SCYBVVGGC		 Transfac
Matys et al.(2006)
V$AP2GAMMA_01 		0.835 0.835
TFAP2C
M09752_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AP2GAMMA_Q4 		0.835 0.835
TFAP2C
M09753_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AP2GAMMA_Q5_01 		0.835 0.835
TFAP2C
M09754_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AP2GAMMA_Q5 		0.835 0.835
TFAP2C
M04049_2.00 		Homo sapiens
NSCCYNRGGSN
NSCCYNRGGSN		 SELEX
Yin et al.(2017)
TFAP2C_eDBD_Methyl-HT-SELEX 		0.835 0.835
TFAP2E
M04050_2.00 		Homo sapiens
HSCCYSRGGSD
HSCCYSRGGSD		 SELEX
Yin et al.(2017)
TFAP2E_FL_HT-SELEX_1 		0.814 0.814
TFAP2E
M04051_2.00 		Homo sapiens
NSCCBBVGGSCA
TGSCCBVVGGSN		 SELEX
Yin et al.(2017)
TFAP2E_FL_HT-SELEX_2 		0.814 0.814
TFAP2E
M04052_2.00 		Homo sapiens
HSCCYSRGGSD
HSCCYSRGGSD		 SELEX
Yin et al.(2017)
TFAP2E_FL_Methyl-HT-SELEX_1 		0.814 0.814
TFAP2E
M04053_2.00 		Homo sapiens
NSCCYNRGGGCR
YGCCCYNRGGSN		 SELEX
Yin et al.(2017)
TFAP2E_FL_Methyl-HT-SELEX_2 		0.814 0.814
Tfap2e
M00114_2.00 		Mus musculus
NNGCCYBVGG
CCBVRGGCNN		 PBM
Badis et al.(2009)
Tcfap2e_3713 		0.809 0.809
AP-2
M03584_2.00 		Drosophila melanogaster
HGCCYSRGGCD
HGCCYSRGGCD		 SELEX
Nitta et al.(2015)
AP-2_1 		0.701 0.701
AP-2
M03585_2.00 		Drosophila melanogaster
HGCCYBVRGGCD
HGCCYBVRGGCD		 SELEX
Nitta et al.(2015)
AP-2_2 		0.701 0.701
AP-2
M03586_2.00 		Drosophila melanogaster
NSCCYBNVRGGCN
NGCCYBNVRGGSN		 SELEX
Nitta et al.(2015)
AP-2_3 		0.701 0.701
AP-2
M03587_2.00 		Drosophila melanogaster
HGCCYNRGGCD
HGCCYNRGGCD		 SELEX
Nitta et al.(2015)
AP-2_4 		0.701 0.701
AP-2
M03588_2.00 		Drosophila melanogaster
HSCCYBVRGGSD
HSCCYBVRGGSD		 SELEX
Nitta et al.(2015)
AP-2_5 		0.701 0.701
AP-2
M03589_2.00 		Drosophila melanogaster
HGCCYBNVRGGCD
HGCCYBNVRGGCD		 SELEX
Nitta et al.(2015)
AP-2_6 		0.701 0.701
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
Afo_R003239 AP-2 47 246

Links

Other AP-2 family TFs
Other Aptenodytes forsteri TFs

372 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Aan_R012729 Calypte anna Aan_R012729 I
Afo_R015662 Aptenodytes forsteri Afo_R015662 I
Brh_R011794 Buceros rhinoceros Brh_R011794 I
ENSAMEG00000008882 Ailuropoda melanoleuca ENSAMEG00000008882 I
ENSAMXG00000003341 Astyanax mexicanus ENSAMXG00000003341 I
ENSAPLG00000013878 Anas platyrhynchos ENSAPLG00000013878 I
NFKB1 Bos taurus ENSBTAG00000020270 I
ENSBTAP00000027016-D1 Bos grunniens ENSBTAP00000027016-D1 I
NFKB1 Canis familiaris ENSCAFG00000010730 I
NFKB1 Callithrix jacchus ENSCJAG00000015382 I
NFKB1 Cavia porcellus ENSCPOG00000007789 I
ENSCSAG00000004049 Chlorocebus sabaeus ENSCSAG00000004049 I
nfkb1 Danio rerio ENSDARG00000105261 I
NFKB1 Dasypus novemcinctus ENSDNOG00000006855 I
Nfkb1 Dipodomys ordii ENSDORG00000007447 I
NFKB1 Equus caballus ENSECAG00000015042 I
ENSFALG00000008136 Ficedula albicollis ENSFALG00000008136 I
NFKB1 Felis catus ENSFCAG00000007557 I
NFKB1 Homo sapiens ENSG00000109320 D
NFKB1 Gallus gallus ENSGALG00000012304 I
NFKB1 Gorilla gorilla ENSGGOG00000009071 I
ENSLACG00000002751 Latimeria chalumnae ENSLACG00000002751 I
NFKB1 Loxodonta africana ENSLAFG00000009344 I
ENSLOCG00000012080 Lepisosteus oculatus ENSLOCG00000012080 I
ENSMEUG00000001334 Macropus eugenii ENSMEUG00000001334 I
NFKB1 Meleagris gallopavo ENSMGAG00000011299 I
NFKB1 Myotis lucifugus ENSMLUG00000005986 I
NFKB1 Macaca mulatta ENSMMUG00000003736 I
NFKB1 Monodelphis domestica ENSMODG00000020672 I
ENSMPUG00000009413 Mustela putorius furo ENSMPUG00000009413 I
Nfkb1 Mus musculus ENSMUSG00000028163 D
ENSNLEG00000013325 Nomascus leucogenys ENSNLEG00000013325 I
ENSOANG00000028755 Ornithorhynchus anatinus ENSOANG00000028755 I
ENSOARG00000012718 Ovis aries ENSOARG00000012718 I
NFKB1 Oryctolagus cuniculus ENSOCUG00000021712 I
NFKB1 Otolemur garnettii ENSOGAG00000012840 I
NFKB1 Ochotona princeps ENSOPRG00000005212 I
ENSP00000226574 Macaca fascicularis ENSP00000226574 I
ENSPANG00000023882 Papio anubis ENSPANG00000023882 I
NFKB1 Procavia capensis ENSPCAG00000008172 I
ENSPPYG00000014965 Pongo abelii ENSPPYG00000014965 I
ENSPSIG00000008515 Pelodiscus sinensis ENSPSIG00000008515 I
NFKB1 Pan troglodytes ENSPTRG00000016320 I
NFKB1 Pteropus vampyrus ENSPVAG00000002722 I
Nfkb1 Rattus norvegicus ENSRNOG00000023258 I
ENSSHAG00000007374 Sarcophilus harrisii ENSSHAG00000007374 I
ENSSTOG00000011445 Ictidomys tridecemlineatus ENSSTOG00000011445 I
NFKB1 Tupaia belangeri ENSTBEG00000003520 I
NFKB1 Taeniopygia guttata ENSTGUG00000003595 I
NFKB1 Tursiops truncatus ENSTTRG00000010852 I
NFKB1 Vicugna pacos ENSVPAG00000000280 I
Gfo_R000994 Geospiza fortis Gfo_R000994 I
Myotis_brandtii_NFKB1_10013135 Myotis brandtii Myotis_brandtii_NFKB1_10013135 I
Ogr10707 Ophisaurus gracilis Ogr10707 I
Pvit_05196 Pogona vitticeps Pvit_05196 I
Tal_R004861 Tyto alba Tal_R004861 I
nfkb1 Xenopus tropicalis XB-GENE-985746 I
nfkb1.L Xenopus laevis XB-GENE-985749 I