CIS-BP Database: Catalog of Inferred Sequence Binding Preferences

TF Information

E(spl)m3-HLH *(Drosophila melanogaster)* bHLH
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF00010 (HLH)	IPR001092	FBgn0002609	T038394_2.00	Ensembl (2018-Dec-8)	Link out
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
E(spl)m3-HLH M03596_2.00	Drosophila melanogaster	DTGGCACGTGCCAH	DTGGCACGTGCCAH	SELEX Nitta et al.(2015) HLHm3_1	(Direct)	(Direct)
E(spl)m3-HLH M05939_2.00	Drosophila melanogaster	CACGTGVCA	TGBCACGTG	B1H Zhu et al.(2011) HLHm3_SANGER_5_FBgn0002609	(Direct)	(Direct)
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
E(spl)mbeta-HLH M03597_2.00	Drosophila melanogaster	HGGCACGTGCCR	YGGCACGTGCCD	SELEX Nitta et al.(2015) HLHmbeta_1	0.890	0.873
E(spl)mbeta-HLH M05945_2.00	Drosophila melanogaster	CRCGTGCC	GGCACGYG	B1H Zhu et al.(2011) HLHmbeta_SANGER_10_FBgn0002733	0.890	0.873
E(spl)mgamma-HLH M03599_2.00	Drosophila melanogaster	DTGGCACGTGCCAH	DTGGCACGTGCCAH	SELEX Nitta et al.(2015) HLHmgamma_1	0.852	0.855
E(spl)mgamma-HLH M05947_2.00	Drosophila melanogaster	SCACGTGCCA	TGGCACGTGS	B1H Zhu et al.(2011) HLHmgamma_SANGER_10_FBgn0002735	0.852	0.855
E(spl)mgamma-HLH M05948_2.00	Drosophila melanogaster	CTTGACW	WGTCAAG	B1H Zhu et al.(2011) HLHmgamma_SANGER_5_2_FBgn0002735	0.852	0.855
For this family, TFs with SR scores > 0.838* will likely have a similar motif*

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
FBpp0084332	bHLH	12	69	RKVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDHMRKLK

Links
Other bHLH family TFs
Other *Drosophila melanogaster* TFs