sbp-1 (Caenorhabditis elegans)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 WBGene00004735 T046302_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables DNA-binding transcription factor activity. Involved in several processes, including determination of adult lifespan; positive regulation of lipid storage; and response to anoxia. Located in nucleus. Is expressed in several structures, including head; intestine; and terminal bulb. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in carotid artery disease; disease of metabolism (multiple); prostate cancer; and vascular dementia. Orthologous to several human genes including SREBF2 (sterol regulatory element binding transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
Y47D3B.7 bHLH 356 406

Links

Other bHLH family TFs
Other Caenorhabditis elegans TFs

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16 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action