| NCBI Gene Info:Enables DNA-binding transcription factor activity. Involved in several processes, including determination of adult lifespan; positive regulation of lipid storage; and response to anoxia. Located in nucleus. Is expressed in several structures, including head; intestine; and terminal bulb. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in carotid artery disease; disease of metabolism (multiple); prostate cancer; and vascular dementia. Orthologous to several human genes including SREBF2 (sterol regulatory element binding transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022] |