CMR3 (Saccharomyces cerevisiae)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 YPR013C T131857_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Townes-Brocks syndrome and middle lobe syndrome. Orthologous to human SALL1 (spalt like transcription factor 1) and SALL3 (spalt like transcription factor 3). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
CMR3
M00042_2.00		 Saccharomyces cerevisiae
HGTARATCN
NGATYTACD		 PBM
Badis et al.(2008)
YPR013C_2104		 (Direct) (Direct)
CMR3
M01539_2.00		 Saccharomyces cerevisiae
NGATYDRCVN
NBGYHRATCN		 PBM
Zhu et al.(2009)
Ypr013c		 (Direct) (Direct)
CMR3
M07471_2.00		 Saccharomyces cerevisiae
NGATYKRCR
YGYMRATCN		 PBM, CSA and or DIP-chip
Mathelier et al.(2014)
MA0434.1		 (Direct) (Direct)
CMR3
M08545_2.00		 Saccharomyces cerevisiae
NNNRVYGTARATCMYDNNNN
NNNNHRKGATYTACRBYNNN		 Misc
DeBoer et al.(2011)
YPR013C_859		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
YPR015C
M01540_2.00 		Saccharomyces cerevisiae
YTSBBBN
NVVVSAR		 PBM
Zhu et al.(2009)
Ypr015c 		0.776 0.848
YPR015C
M08546_2.00 		Saccharomyces cerevisiae
BNNNDVCGTAAATCMYNDHH
DDHNRKGATTTACGBHNNNV		 Misc
DeBoer et al.(2011)
YPR015C_871 		0.776 0.848
For this family, TFs with SR scores > 0.755 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00042_2.00 C2H2 ZF 51 73
M00042_2.00 C2H2 ZF 79 103
M01539_2.00 C2H2 ZF 254 276
M01539_2.00 C2H2 ZF 282 306

DNA Binding Domains

Protein ID Domain From To Sequence
YPR013C C2H2 ZF 254 276
YPR013C C2H2 ZF 282 306

Links

Other C2H2 ZF family TFs
Other Saccharomyces cerevisiae TFs

Invalid Input OrderBy

30 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action