IRX4 (Equus caballus)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSECAG00000017403 T209159_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Irx4
M00416_2.00
Mus musculus
NNNDAMAH

DTKTHNNN
PBM
Berger et al.(2008)
Irx4_2242
0.867 1.000
Irx6
M00456_2.00
Mus musculus
NNDAHWN

NWDTHNN
PBM
Berger et al.(2008)
Irx6_2623
0.790 0.929
ara
M06518_2.00
Drosophila melanogaster
WWACA

TGTWW
B1H
Mathelier et al.(2014)
MA0210.1
0.788 0.929
ara
M06313_2.00
Drosophila melanogaster
TGTWWWNN

NNWWWACA
B1H
Zhu et al.(2011)
Ara_Cell_FBgn0015904
0.788 0.929
ara
M06314_2.00
Drosophila melanogaster
DWWACA

TGTWWH
B1H
Zhu et al.(2011)
Ara_SOLEXA_FBgn0015904
0.788 0.929
caup
M06519_2.00
Drosophila melanogaster
WAACA

TGTTW
B1H
Mathelier et al.(2014)
MA0217.1
0.780 0.893
caup
M06315_2.00
Drosophila melanogaster
HWDWAACA

TGTTWHWD
B1H
Zhu et al.(2011)
Caup_Cell_FBgn0015919
0.780 0.893
caup
M06316_2.00
Drosophila melanogaster
NDDACA

TGTHHN
B1H
Zhu et al.(2011)
Caup_SOLEXA_FBgn0015919
0.780 0.893
Irx2
M00386_2.00
Mus musculus
NNDACAHNN

NNDTGTHNN
PBM
Berger et al.(2008)
Irx2_0900
0.780 0.893
Irx5
M00455_2.00
Mus musculus
NNNDACAHN

NDTGTHNNN
PBM
Berger et al.(2008)
Irx5_2385
0.780 0.893
IRX2
M03212_2.00
Homo sapiens
NDACAYRACAHN

NDTGTYRTGTHN
SELEX
Jolma et al.(2013)
IRX2_1
0.780 0.893
IRX5
M03222_2.00
Homo sapiens
NDACAYRACAHN

NDTGTYRTGTHN
SELEX
Jolma et al.(2013)
IRX5_1
0.780 0.893
IRX5
M05315_2.00
Homo sapiens
NBDTGTHNDACAYVN

NBRTGTHNDACAHVN
SELEX
Yin et al.(2017)
IRX5_eDBD_HT-SELEX
0.780 0.893
IRX5
M05316_2.00
Homo sapiens
WYRYGHHNHAYRYRY

RYRYRTDNDDCRYRW
SELEX
Yin et al.(2017)
IRX5_eDBD_Methyl-HT-SELEX
0.780 0.893
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSECAP00000015043 Homeodomain 142 200

Links

Other Homeodomain family TFs
Other Equus caballus TFs

389 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
AAEL013374 Aedes aegypti AAEL013374 N
AALB007335 Anopheles albimanus AALB007335 I 0.788
Aan_R002773 Calypte anna Aan_R002773 I 0.781
AARA003608 Anopheles arabiensis AARA003608 I 0.788
AATE000074 Anopheles atroparvus AATE000074 I 0.788
AAY89592 Xenopus tropicalis AAY89592 I 0.780
ACHR000365 Anopheles christyi ACHR000365 I 0.788
ACOM024408 Anopheles coluzzii ACOM024408 I 0.788
ACUA001765 Anopheles culicifacies ACUA001765 I 0.788
ADIR001596 Anopheles dirus ADIR001596 I 0.788
AEPI004232 Anopheles epiroticus AEPI004232 I 0.788
AEPI009424 Anopheles epiroticus AEPI009424 N
Afo_R008293 Aptenodytes forsteri Afo_R008293 I 0.624
Afo_R008294 Aptenodytes forsteri Afo_R008294 I 0.781
AFUN000312 Anopheles funestus AFUN000312 I 0.788
Alligator_sinensis_CCG008450.1 Alligator sinensis Alligator_sinensis_CCG008450.1 I 0.780
AMAM014362 Anopheles maculatus AMAM014362 N
AMAM019276 Anopheles maculatus AMAM019276 I 0.788
AMEC001747 Anopheles melas AMEC001747 I 0.788
AMEM004461 Anopheles merus AMEM004461 I 0.788
AMIN011494 Anopheles minimus AMIN011494 I 0.788
ANCCAN_18840 Ancylostoma caninum ANCCAN_18840 N
ANCDUO_15583 Ancylostoma duodenale ANCDUO_15583 N
AQUA009986 Anopheles quadriannulatus AQUA009986 I 0.788
ASTEI09300 Anopheles stephensi ASTEI09300 I 0.788
BGLB008222 Biomphalaria glabrata BGLB008222 N
Brh_R007203 Buceros rhinoceros Brh_R007203 I 0.779
BTMF_0001429901 Brugia timori BTMF_0001429901 N
BXY_0138900 Bursaphelenchus xylophilus BXY_0138900 I 0.748
BXY_1034900 Bursaphelenchus xylophilus BXY_1034900 I
BXY_1035000 Bursaphelenchus xylophilus BXY_1035000 N
CapteG168300 Capitella teleta CapteG168300 I 0.758
CapteG78125 Capitella teleta CapteG78125 N
Cflo_05544--XP_396292.3_APIME Camponotus floridanus Cflo_05544--XP_396292.3_APIME I 0.788
CLEC006296 Cimex lectularius CLEC006296 N
CLEC025387 Cimex lectularius CLEC025387 I 0.788
Cmyd_10013669 Chelonia mydas Cmyd_10013669 I 0.780
csin107852 Clonorchis sinensis csin107852 I 0.709
csin108827 Clonorchis sinensis csin108827 I 0.651
D917_04255 Trichinella nativa D917_04255 N
D917_07736 Trichinella nativa D917_07736 I 0.788
D918_00954 Trichuris suis D918_00954 N
D918_04764 Trichuris suis D918_04764 I 0.788
DAPPUDRAFT_28488 Daphnia pulex DAPPUDRAFT_28488 I 0.780
ECANG7_08582 Echinococcus canadensis ECANG7_08582 I 0.769
ECANG7_08640 Echinococcus canadensis ECANG7_08640 I 0.700
EFV51389 Trichinella spiralis EFV51389 I 0.788
EFV52039 Trichinella spiralis EFV52039 N
EmuJ_000784500 Echinococcus multilocularis EmuJ_000784500 I 0.769
IRX2 Anolis carolinensis ENSACAG00000000694 I 0.781
ENSAMEG00000013363 Ailuropoda melanoleuca ENSAMEG00000013363 I 0.780
ENSAMXG00000005721 Astyanax mexicanus ENSAMXG00000005721 I 0.780
ENSAPLG00000009168 Anas platyrhynchos ENSAPLG00000009168 I 0.781
IRX5 Bos taurus ENSBTAG00000004838 I 0.780
ENSBTAG00000047499 Bos taurus ENSBTAG00000047499 I 0.780
ENSBTAP00000006356-D1 Bos grunniens ENSBTAP00000006356-D1 I 0.780
IRX5 Canis familiaris ENSCAFG00000009443 I 0.780
ENSCAFG00000010422 Canis familiaris ENSCAFG00000010422 I 0.485
IRX2 Canis familiaris ENSCAFG00000010427 I 0.780
ENSCING00000012537 Ciona intestinalis ENSCING00000012537 I 0.768
IRX2 Callithrix jacchus ENSCJAG00000008516 I 0.780
IRX5 Callithrix jacchus ENSCJAG00000012968 I 0.780
IRX2 Cavia porcellus ENSCPOG00000000858 I 0.781
IRX5 Cavia porcellus ENSCPOG00000011984 I 0.780
ENSCSAG00000005287 Chlorocebus sabaeus ENSCSAG00000005287 I 0.780
ENSCSAG00000017353 Chlorocebus sabaeus ENSCSAG00000017353 I 0.780
irx2a Danio rerio ENSDARG00000001785 I 0.781
irx5a Danio rerio ENSDARG00000034043 I 0.780
irx5b Danio rerio ENSDARG00000074070 I 0.772
ENSDNOG00000002196 Dasypus novemcinctus ENSDNOG00000002196 I 0.781
IRX2 Equus caballus ENSECAG00000015758 I 0.780
ENSECAG00000023545 Equus caballus ENSECAG00000023545 I 0.764
IRX5 Erinaceus europaeus ENSEEUG00000015645 I 0.765
ENSFALG00000005243 Ficedula albicollis ENSFALG00000005243 I 0.781
ENSFCAG00000023076 Felis catus ENSFCAG00000023076 I 0.780
IRX2 Homo sapiens ENSG00000170561 D 0.780
IRX5 Homo sapiens ENSG00000176842 D 0.780
irx2a Gasterosteus aculeatus ENSGACG00000006581 I 0.781
irx5b Gasterosteus aculeatus ENSGACG00000007829 I 0.780
irx5a Gasterosteus aculeatus ENSGACG00000016681 I 0.772
IRX2 Gallus gallus ENSGALG00000013193 I 0.781
IRX2 Gorilla gorilla ENSGGOG00000015712 I 0.780
IRX5 Gorilla gorilla ENSGGOG00000027776 I 0.780
ENSGMOG00000000641 Gadus morhua ENSGMOG00000000641 I 0.780
ENSGMOG00000004163 Gadus morhua ENSGMOG00000004163 I 0.780
ENSGMOG00000006674 Gadus morhua ENSGMOG00000006674 I 0.781
ENSLACG00000002708 Latimeria chalumnae ENSLACG00000002708 I 0.781
ENSLACG00000015837 Latimeria chalumnae ENSLACG00000015837 I 0.780
ENSLACG00000017763 Latimeria chalumnae ENSLACG00000017763 I 0.710
IRX5 Loxodonta africana ENSLAFG00000000090 I 0.780
IRX2 Loxodonta africana ENSLAFG00000031893 I 0.780
ENSLOCG00000006946 Lepisosteus oculatus ENSLOCG00000006946 I 0.702
ENSLOCG00000007105 Lepisosteus oculatus ENSLOCG00000007105 I 0.780
ENSLOCG00000008842 Lepisosteus oculatus ENSLOCG00000008842 I 0.781
ENSMEUG00000008376 Macropus eugenii ENSMEUG00000008376 I 0.780
ENSMEUG00000011565 Macropus eugenii ENSMEUG00000011565 I 0.781
ENSMEUG00000014864 Macropus eugenii ENSMEUG00000014864 I 0.716
ENSMICG00000002308 Microcebus murinus ENSMICG00000002308 I 0.780
IRX2 Microcebus murinus ENSMICG00000013531 I 0.780
IRX2 Myotis lucifugus ENSMLUG00000002364 I 0.780
IRX5 Myotis lucifugus ENSMLUG00000026571 I 0.780
IRX2 Macaca mulatta ENSMMUG00000005802 I 0.780
IRX5 Macaca mulatta ENSMMUG00000017440 I 0.780
ENSMMUP00000022960 Macaca fascicularis ENSMMUP00000022960 I 0.780
IRX2 Monodelphis domestica ENSMODG00000001446 I 0.781
IRX5 Monodelphis domestica ENSMODG00000013202 I 0.780
ENSMPUG00000003373 Mustela putorius furo ENSMPUG00000003373 I 0.780
ENSMPUG00000007638 Mustela putorius furo ENSMPUG00000007638 I 0.485
ENSMPUG00000007647 Mustela putorius furo ENSMPUG00000007647 I 0.780
Irx2 Mus musculus ENSMUSG00000001504 D 0.780
Irx5 Mus musculus ENSMUSG00000031737 D 0.780
ENSNLEG00000001190 Nomascus leucogenys ENSNLEG00000001190 I 0.780
ENSNLEG00000011219 Nomascus leucogenys ENSNLEG00000011219 I 0.780
ENSOANG00000001748 Ornithorhynchus anatinus ENSOANG00000001748 I 0.781
ENSOANG00000029378 Ornithorhynchus anatinus ENSOANG00000029378 I 0.485
ENSOARG00000011056 Ovis aries ENSOARG00000011056 I 0.765
IRX5 Oryctolagus cuniculus ENSOCUG00000003240 I 0.780
IRX2 Oryctolagus cuniculus ENSOCUG00000009172 I 0.780
IRX5 Otolemur garnettii ENSOGAG00000004133 I 0.780
IRX2 Otolemur garnettii ENSOGAG00000012910 I 0.780
ENSONIG00000002806 Oreochromis niloticus ENSONIG00000002806 I 0.780
ENSONIG00000007110 Oreochromis niloticus ENSONIG00000007110 I 0.781
ENSONIG00000016567 Oreochromis niloticus ENSONIG00000016567 I 0.714
IRX5 Ochotona princeps ENSOPRG00000003007 I 0.780
IRX2 Ochotona princeps ENSOPRG00000012917 I 0.780
irx2a Oryzias latipes ENSORLG00000005150 I 0.781
irx5a Oryzias latipes ENSORLG00000013711 I 0.780
ENSP00000372056 Macaca fascicularis ENSP00000372056 I 0.780
ENSPANG00000003730 Papio anubis ENSPANG00000003730 I 0.780
ENSPANG00000007155 Papio anubis ENSPANG00000007155 I 0.780
IRX5 Procavia capensis ENSPCAG00000003649 I 0.776
ENSPFOG00000016012 Poecilia formosa ENSPFOG00000016012 I 0.780
ENSPFOG00000016014 Poecilia formosa ENSPFOG00000016014 I 0.780
ENSPFOG00000016596 Poecilia formosa ENSPFOG00000016596 I 0.781
ENSPMAG00000002391 Petromyzon marinus ENSPMAG00000002391 I 0.778
ENSPPYG00000007355 Pongo abelii ENSPPYG00000007355 I 0.780
ENSPPYG00000015325 Pongo abelii ENSPPYG00000015325 I 0.780
ENSPSIG00000006956 Pelodiscus sinensis ENSPSIG00000006956 I 0.780
ENSPSIG00000016741 Pelodiscus sinensis ENSPSIG00000016741 I 0.780
IRX5 Pan troglodytes ENSPTRG00000008121 I 0.780
IRX2 Pan troglodytes ENSPTRG00000016708 I 0.780
IRX2 Pteropus vampyrus ENSPVAG00000001273 I 0.780
IRX5 Pteropus vampyrus ENSPVAG00000005731 I 0.780
Irx5 Rattus norvegicus ENSRNOG00000011180 I 0.780
Irx3 Rattus norvegicus ENSRNOG00000011533 I 0.485
Irx2 Rattus norvegicus ENSRNOG00000012742 I 0.780
ENSSHAG00000001675 Sarcophilus harrisii ENSSHAG00000001675 I 0.781
ENSSHAG00000006589 Sarcophilus harrisii ENSSHAG00000006589 I 0.780
ENSSTOG00000003533 Ictidomys tridecemlineatus ENSSTOG00000003533 I 0.780
ENSSTOG00000023408 Ictidomys tridecemlineatus ENSSTOG00000023408 I 0.780
IRX2 Taeniopygia guttata ENSTGUG00000008512 I 0.781
ENSTNIG00000000637 Tetraodon nigroviridis ENSTNIG00000000637 I 0.714
irx2a Tetraodon nigroviridis ENSTNIG00000007221 I 0.781
irx5a Tetraodon nigroviridis ENSTNIG00000013613 I 0.780
irx2a Takifugu rubripes ENSTRUG00000001420 I 0.781
irx2a Takifugu rubripes ENSTRUG00000007607 I 0.781
irx5a Takifugu rubripes ENSTRUG00000010063 I 0.780
IRX2 Tursiops truncatus ENSTTRG00000006214 I 0.778
ara Drosophila melanogaster FBgn0015904 D 0.788
caup Drosophila melanogaster FBgn0015919 D 0.780
GA10403 Drosophila pseudoobscura FBgn0070460 I 0.788
GA10434 Drosophila pseudoobscura FBgn0070491 I 0.780
GF17143 Drosophila ananassae FBgn0094162 N
GF17175 Drosophila ananassae FBgn0094193 N
GF24688 Drosophila ananassae FBgn0101681 I 0.788
GF24689 Drosophila ananassae FBgn0101682 I 0.780
GG15584 Drosophila erecta FBgn0107830 I 0.788
GG15585 Drosophila erecta FBgn0107831 I 0.780
GH12158 Drosophila grimshawi FBgn0119637 N
GH14715 Drosophila grimshawi FBgn0122191 I 0.788
GH14716 Drosophila grimshawi FBgn0122192 I 0.780
GI10902 Drosophila mojavensis FBgn0133665 N
GI12261 Drosophila mojavensis FBgn0135018 I 0.788
GI12262 Drosophila mojavensis FBgn0135019 I 0.780
GL25202 Drosophila persimilis FBgn0162786 I 0.788
GL25204 Drosophila persimilis FBgn0162788 I 0.780
GM25355 Drosophila sechellia FBgn0180213 I 0.788
GM25358 Drosophila sechellia FBgn0180216 I 0.780
GD14388 Drosophila simulans FBgn0186071 I 0.788
GD14390 Drosophila simulans FBgn0186073 I 0.780
GJ11492 Drosophila virilis FBgn0198750 I 0.788
GJ11493 Drosophila virilis FBgn0198751 I 0.780
GJ18548 Drosophila virilis FBgn0205706 N
GK10560 Drosophila willistoni FBgn0212575 I 0.788
GK10562 Drosophila willistoni FBgn0212577 I 0.780
GE21912 Drosophila yakuba FBgn0239150 I 0.788
GE21913 Drosophila yakuba FBgn0239151 I 0.780
GB55196 Apis mellifera GB55196 I 0.788
Hba_07323 Heterorhabditis bacteriophora Hba_07323 N
HCOI00051800 Haemonchus contortus HCOI00051800 N
HDID_0000776001 Hymenolepis diminuta HDID_0000776001 I 0.700
HDID_0000922001 Hymenolepis diminuta HDID_0000922001 I 0.781
HelroG74370 Helobdella robusta HelroG74370 I 0.743
HHAL001513-PA Halyomorpha halys HHAL001513-PA N
HHAL007381-PA Halyomorpha halys HHAL007381-PA I 0.788
HMEL008471 Heliconius melpomene HMEL008471 I 0.788
HMEL014400 Heliconius melpomene HMEL014400 N
HmN_000285700 Hymenolepis microstoma HmN_000285700 I 0.781
HmN_000708300 Hymenolepis microstoma HmN_000708300 I 0.688
HNAJ_0000146901 Hymenolepis nana HNAJ_0000146901 I 0.688
HNAJ_0000526401 Hymenolepis nana HNAJ_0000526401 I 0.781
HPBE_0000946001 Heligmosomoides bakeri HPBE_0000946001 N
Hsal_07613--XP_396292.3_APIME Harpegnathos saltator Hsal_07613--XP_396292.3_APIME I 0.788
ISCW012614 Ixodes scapularis ISCW012614 I 0.615
ISCW018372 Ixodes scapularis ISCW018372 N
KGM_15162 Danaus plexippus KGM_15162 I 0.788
KGM_20032 Danaus plexippus KGM_20032 N
L596_g21741 Steinernema carpocapsae L596_g21741 I 0.762
L798_06794 Zootermopsis nevadensis L798_06794 I 0.788
L889_g7581 Steinernema feltiae L889_g7581 I 0.762
L892_g27267 Steinernema scapterisci L892_g27267 I 0.762
L898_g6461 Steinernema monticolum L898_g6461 I 0.762
LCUP009247 Lucilia cuprina LCUP009247 N
LCUP015174 Lucilia cuprina LCUP015174 I 0.788
LCUP015460 Lucilia cuprina LCUP015460 I 0.788
LCUP015462 Lucilia cuprina LCUP015462 I 0.788
LDEC015753 Leptinotarsa decemlineata LDEC015753 I 0.788
MCINX001662 Melitaea cinxia MCINX001662 I 0.788
MCINX008008 Melitaea cinxia MCINX008008 N
MCOS_0000014901 Mesocestoides corti MCOS_0000014901 I 0.638
MDOA003906 Musca domestica MDOA003906 I 0.788
MDOA004752 Musca domestica MDOA004752 I 0.788
MDOA010514 Musca domestica MDOA010514 N
MDOA012478 Musca domestica MDOA012478 I 0.788
MESCA003747 Megaselia scalaris MESCA003747 I 0.788
MESCA007831 Megaselia scalaris MESCA007831 I 0.780
MhA1_Contig488.frz3.gene7 Meloidogyne hapla MhA1_Contig488.frz3.gene7 I 0.754
Minc05254 Meloidogyne incognita Minc05254 N
Minc12099 Meloidogyne incognita Minc12099 I 0.746
Myotis_brandtii_Irx1_10035798 Myotis brandtii Myotis_brandtii_Irx1_10035798 I 0.485
Myotis_brandtii_IRX2_10035801 Myotis brandtii Myotis_brandtii_IRX2_10035801 I 0.780
Myotis_brandtii_IRX5_10004763 Myotis brandtii Myotis_brandtii_IRX5_10004763 I 0.780
NECAME_09957 Necator americanus NECAME_09957 N
nRc.2.0.1.g39124 Romanomermis culicivorax nRc.2.0.1.g39124 N
NV13312 Nasonia vitripennis NV13312 I 0.788
Ocbimv22017187m.g Octopus bimaculoides Ocbimv22017187m.g I 0.788
Ocbimv22021956m.g Octopus bimaculoides Ocbimv22021956m.g I 0.788
Ocbimv22027669m.g Octopus bimaculoides Ocbimv22027669m.g I 0.788
Ogr18478 Ophisaurus gracilis Ogr18478 I 0.485
Ogr18480 Ophisaurus gracilis Ogr18480 I 0.781
PHUM403340 Pediculus humanus PHUM403340 I 0.788
PHUM562240 Pediculus humanus PHUM562240 I 0.788
PPAI010026 Phlebotomus papatasi PPAI010026 I 0.788
PTRK_0001274900 Parastrongyloides trichosuri PTRK_0001274900 N
Pvit_14760 Pogona vitticeps Pvit_14760 I 0.781
Pvit_18667 Pogona vitticeps Pvit_18667 I 0.780
RPRC002305 Rhodnius prolixus RPRC002305 I 0.788
RPRC004296 Rhodnius prolixus RPRC004296 N
SINV10244 Solenopsis invicta SINV10244 I 0.788
Sjc_0031820 Schistosoma japonicum Sjc_0031820 I 0.678
Sjc_0031830 Schistosoma japonicum Sjc_0031830 I 0.678
SMAR007687 Strigamia maritima SMAR007687 I 0.485
Smp_149230 Schistosoma mansoni Smp_149230 I 0.679
SMTD_0002243001 Schistosoma mattheei SMTD_0002243001 I 0.485
SNAPOd2T00027338001 Oikopleura dioica SNAPOd2T00027338001 I 0.649
SSLN_0000725901 Schistocephalus solidus SSLN_0000725901 I 0.739
SVUK_0000102101 Strongylus vulgaris SVUK_0000102101 N
T265_13435 Opisthorchis viverrini T265_13435 I 0.709
TASK_0000023001 Taenia asiatica TASK_0000023001 I 0.700
TASK_0000435901 Taenia asiatica TASK_0000435901 I 0.740
TC001693 Tribolium castaneum TC001693 N
TC003632 Tribolium castaneum TC003632 I 0.788
tetur05g03220 Tetranychus urticae tetur05g03220 I 0.786
TMUE_s0040004400 Trichuris muris TMUE_s0040004400 I 0.788
TsM_000262600 Taenia solium TsM_000262600 I 0.700
TsM_000636600 Taenia solium TsM_000636600 I 0.740
TTAC_0000065401 Hydatigera taeniaeformis TTAC_0000065401 I 0.700
TTRE_0000475501 Trichuris trichiura TTRE_0000475501 I 0.788
TTRE_0000574401 Trichuris trichiura TTRE_0000574401 N
irx6 Xenopus tropicalis XB-GENE-479932 I 0.777
irx2 Xenopus tropicalis XB-GENE-480618 I 0.781
irx2.L Xenopus laevis XB-GENE-865393 I 0.781
irx1.L Xenopus laevis XB-GENE-865648 I 0.727
XP_002166749.1 Hydra magnipapillata XP_002166749.1 I 0.786