HNF1A (Homo sapiens)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSG00000135100 T209844_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
HNF1A
M03150_2.00		 Homo sapiens
NGTTAATNATTAAYN
NRTTAATNATTAACN		 SELEX
Jolma et al.(2013)
HNF1A_1		 (Direct) (Direct)
HNF1A
M09144_2.00		 Homo sapiens
DGTTAATKATTAACH
DGTTAATMATTAACH		 Misc
Kulakovskiy et al.(2013)
HNF1A_HUMAN.H11MO.0.C		 (Direct) (Direct)
HNF1A
M10690_2.00		 Homo sapiens
RGTTAATDWTTRMHV
BDKYAAWHATTAACY		 Transfac
Matys et al.(2006)
V$HNF1_01		 (Direct) (Direct)
HNF1A
M10691_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF1A_Q4		 (Direct) (Direct)
HNF1A
M10692_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF1A_Q5		 (Direct) (Direct)
HNF1A
M10693_2.00		 Homo sapiens
DGBTAATBAWTHAMYWM
KWRKTDAWTVATTAVCH		 Transfac
Matys et al.(2006)
V$HNF1_C		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Hnf1b
M00408_2.00 		Mus musculus
NNHWCNNN
NNNGWDNN		 PBM
Berger et al.(2008)
Tcf2_0913 		0.866 0.945
HNF1B
M03245_2.00 		Homo sapiens
GTTAATNATTAAY
RTTAATNATTAAC		 SELEX
Jolma et al.(2013)
HNF1B_1 		0.866 0.945
HNF1B
M03246_2.00 		Homo sapiens
NGTTAATNATTAAYN
NRTTAATNATTAACN		 SELEX
Jolma et al.(2013)
HNF1B_2 		0.866 0.945
HNF1B
M09168_2.00 		Homo sapiens
DGTTAATRATTAACH
DGTTAATYATTAACH		 Misc
Kulakovskiy et al.(2013)
HNF1B_HUMAN.H11MO.0.A 		0.866 0.945
Hnf1b
M09179_2.00 		Mus musculus
DGTTAATRATTAACH
DGTTAATYATTAACH		 Misc
Kulakovskiy et al.(2013)
HNF1B_MOUSE.H11MO.0.A 		0.866 0.945
HNF1B
M10758_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF1B_Q6_01 		0.866 0.945
HNF1B
M10759_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF1B_Q6 		0.866 0.945
HNF1B
M10760_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$LFA1_Q6 		0.866 0.945
Hnf1a
M00171_2.00 		Mus musculus
HTAAYYNN
NNRRTTAD		 PBM
Badis et al.(2009)
Tcf1_2666 		0.860 0.982
Hnf1a
M00444_2.00 		Mus musculus
HTAAYYNNN
NNNRRTTAD		 PBM
Berger et al.(2008)
Tcf1_2666 		0.860 0.982
Hnf1a
M09191_2.00 		Mus musculus
RGTTAATNWTTDMHN
NDKHAAWNATTAACY		 Misc
Kulakovskiy et al.(2013)
HNF1A_MOUSE.H11MO.0.A 		0.860 0.982
Hmbox1
M00419_2.00 		Mus musculus
NNNGWNNN
NNNWCNNN		 PBM
Berger et al.(2008)
Hmbox1_2674 		0.638 0.382
HMBOX1
M03167_2.00 		Homo sapiens
BKTAACTARB
VYTAGTTAMV		 SELEX
Jolma et al.(2013)
HMBOX1_1 		0.638 0.382
HMBOX1
M05180_2.00 		Homo sapiens
BTAACYAGB
VCTRGTTAV		 SELEX
Yin et al.(2017)
HMBOX1_eDBD_HT-SELEX 		0.638 0.382
HMBOX1
M05181_2.00 		Homo sapiens
NTAACTAGB
VCTAGTTAN		 SELEX
Yin et al.(2017)
HMBOX1_eDBD_Methyl-HT-SELEX 		0.638 0.382
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000257555 Homeodomain 200 275
ENSP00000438804 Homeodomain 200 275
ENSP00000440361 Homeodomain 200 238
ENSP00000443112 Homeodomain 200 275
ENSP00000453965 Homeodomain 248 294
ENSP00000476181 Homeodomain 200 275

Links

Other Homeodomain family TFs
Other Homo sapiens TFs

221 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Aan_R007397 Calypte anna Aan_R007397 I 0.000
Afo_R006360 Aptenodytes forsteri Afo_R006360 I 0.000
Alligator_sinensis_CCG006744.1 Alligator sinensis Alligator_sinensis_CCG006744.1 I 0.000
Brh_R013202 Buceros rhinoceros Brh_R013202 I 0.000
LCORL Anolis carolinensis ENSACAG00000002012 I 0.000
ENSAMEG00000000192 Ailuropoda melanoleuca ENSAMEG00000000192 I 0.000
ENSAPLG00000006384 Anas platyrhynchos ENSAPLG00000006384 I 0.000
LCORL Bos taurus ENSBTAG00000046561 I 0.000
LCORL Canis familiaris ENSCAFG00000016672 I 0.000
LCORL Callithrix jacchus ENSCJAG00000012800 I 0.000
ENSCPOG00000003269 Cavia porcellus ENSCPOG00000003269 I 0.000
ENSCSAG00000016522 Chlorocebus sabaeus ENSCSAG00000016522 I 0.000
lcorl Danio rerio ENSDARG00000070098 I 0.000
LCORL Dasypus novemcinctus ENSDNOG00000001545 I 0.000
ENSDORG00000003797 Dipodomys ordii ENSDORG00000003797 I 0.000
LCORL Equus caballus ENSECAG00000000648 I 0.000
LCORL Erinaceus europaeus ENSEEUG00000000419 I 0.000
ENSFALG00000009227 Ficedula albicollis ENSFALG00000009227 I 0.000
LCORL Felis catus ENSFCAG00000029474 I 0.000
LCORL Homo sapiens ENSG00000178177 D 0.000
LCORL Gallus gallus ENSGALG00000014421 I 0.000
LCORL Gorilla gorilla ENSGGOG00000014894 I 0.000
ENSLACG00000017771 Latimeria chalumnae ENSLACG00000017771 I 0.000
LCORL Loxodonta africana ENSLAFG00000009691 I 0.000
LCORL Meleagris gallopavo ENSMGAG00000012554 I 0.000
ENSMICG00000008878 Microcebus murinus ENSMICG00000008878 I 0.000
LCORL Myotis lucifugus ENSMLUG00000013781 I 0.000
LCORL Monodelphis domestica ENSMODG00000000757 I 0.000
ENSMPUG00000002301 Mustela putorius furo ENSMPUG00000002301 I 0.000
Lcorl Mus musculus ENSMUSG00000015882 I 0.000
ENSNLEG00000016679 Nomascus leucogenys ENSNLEG00000016679 I 0.000
LCORL Oryctolagus cuniculus ENSOCUG00000006802 I 0.000
LCORL Otolemur garnettii ENSOGAG00000005593 I 0.000
ENSP00000371661 Macaca fascicularis ENSP00000371661 I 0.000
ENSP00000371661-D1 Bos grunniens ENSP00000371661-D1 I 0.000
ENSPANG00000024022 Papio anubis ENSPANG00000024022 I 0.000
LCORL Procavia capensis ENSPCAG00000007105 I 0.000
ENSPSIG00000017051 Pelodiscus sinensis ENSPSIG00000017051 I 0.000
LCORL Pan troglodytes ENSPTRG00000015943 I 0.000
LCORL Pteropus vampyrus ENSPVAG00000013601 I 0.000
ENSSHAG00000015746 Sarcophilus harrisii ENSSHAG00000015746 I 0.000
LCORL Sus scrofa ENSSSCG00000008748 I 0.000
ENSSTOG00000000960 Ictidomys tridecemlineatus ENSSTOG00000000960 I 0.000
LCORL Taeniopygia guttata ENSTGUG00000009625 I 0.000
ENSTSYG00000014055 Tarsius syrichta ENSTSYG00000014055 I 0.000
LCORL Tursiops truncatus ENSTTRG00000016951 I 0.000
LCORL Vicugna pacos ENSVPAG00000010356 I 0.000
Gfo_R010322 Geospiza fortis Gfo_R010322 I 0.000
Myotis_brandtii_LCORL_10024397 Myotis brandtii Myotis_brandtii_LCORL_10024397 I 0.000
Ogr00836 Ophisaurus gracilis Ogr00836 I 0.000
Pvit_18026 Pogona vitticeps Pvit_18026 I 0.000
Tal_R001804 Tyto alba Tal_R001804 I 0.000