Hnf1a (Mus musculus)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSMUSG00000029556 T212455_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Hnf1a
M00171_2.00		 Mus musculus
HTAAYYNN
NNRRTTAD		 PBM
Badis et al.(2009)
Tcf1_2666		 (Direct) (Direct)
Hnf1a
M00444_2.00		 Mus musculus
HTAAYYNNN
NNNRRTTAD		 PBM
Berger et al.(2008)
Tcf1_2666		 (Direct) (Direct)
Hnf1a
M09191_2.00		 Mus musculus
RGTTAATNWTTDMHN
NDKHAAWNATTAACY		 Misc
Kulakovskiy et al.(2013)
HNF1A_MOUSE.H11MO.0.A		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
HNF1A
M03150_2.00 		Homo sapiens
NGTTAATNATTAAYN
NRTTAATNATTAACN		 SELEX
Jolma et al.(2013)
HNF1A_1 		0.860 0.982
HNF1A
M09144_2.00 		Homo sapiens
DGTTAATKATTAACH
DGTTAATMATTAACH		 Misc
Kulakovskiy et al.(2013)
HNF1A_HUMAN.H11MO.0.C 		0.860 0.982
HNF1A
M10690_2.00 		Homo sapiens
RGTTAATDWTTRMHV
BDKYAAWHATTAACY		 Transfac
Matys et al.(2006)
V$HNF1_01 		0.860 0.982
HNF1A
M10691_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF1A_Q4 		0.860 0.982
HNF1A
M10692_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF1A_Q5 		0.860 0.982
HNF1A
M10693_2.00 		Homo sapiens
DGBTAATBAWTHAMYWM
KWRKTDAWTVATTAVCH		 Transfac
Matys et al.(2006)
V$HNF1_C 		0.860 0.982
Hnf1b
M00408_2.00 		Mus musculus
NNHWCNNN
NNNGWDNN		 PBM
Berger et al.(2008)
Tcf2_0913 		0.859 0.927
HNF1B
M03245_2.00 		Homo sapiens
GTTAATNATTAAY
RTTAATNATTAAC		 SELEX
Jolma et al.(2013)
HNF1B_1 		0.859 0.927
HNF1B
M03246_2.00 		Homo sapiens
NGTTAATNATTAAYN
NRTTAATNATTAACN		 SELEX
Jolma et al.(2013)
HNF1B_2 		0.859 0.927
HNF1B
M09168_2.00 		Homo sapiens
DGTTAATRATTAACH
DGTTAATYATTAACH		 Misc
Kulakovskiy et al.(2013)
HNF1B_HUMAN.H11MO.0.A 		0.859 0.927
Hnf1b
M09179_2.00 		Mus musculus
DGTTAATRATTAACH
DGTTAATYATTAACH		 Misc
Kulakovskiy et al.(2013)
HNF1B_MOUSE.H11MO.0.A 		0.859 0.927
HNF1B
M10758_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF1B_Q6_01 		0.859 0.927
HNF1B
M10759_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF1B_Q6 		0.859 0.927
HNF1B
M10760_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$LFA1_Q6 		0.859 0.927
Hmbox1
M00419_2.00 		Mus musculus
NNNGWNNN
NNNWCNNN		 PBM
Berger et al.(2008)
Hmbox1_2674 		0.638 0.382
HMBOX1
M03167_2.00 		Homo sapiens
BKTAACTARB
VYTAGTTAMV		 SELEX
Jolma et al.(2013)
HMBOX1_1 		0.638 0.382
HMBOX1
M05180_2.00 		Homo sapiens
BTAACYAGB
VCTRGTTAV		 SELEX
Yin et al.(2017)
HMBOX1_eDBD_HT-SELEX 		0.638 0.382
HMBOX1
M05181_2.00 		Homo sapiens
NTAACTAGB
VCTAGTTAN		 SELEX
Yin et al.(2017)
HMBOX1_eDBD_Methyl-HT-SELEX 		0.638 0.382
For this family, TFs with SR scores > 0.599 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00171_2.00 Homeodomain 17 92
M00444_2.00 Homeodomain 17 92

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000031535 Homeodomain 200 275
ENSMUSP00000135678 Homeodomain 200 244

Links

Other Homeodomain family TFs
Other Mus musculus TFs

220 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSAMEG00000008387 Ailuropoda melanoleuca ENSAMEG00000008387 I 0.860
ENSAMXG00000004039 Astyanax mexicanus ENSAMXG00000004039 I 0.860
ENSAMXG00000005661 Astyanax mexicanus ENSAMXG00000005661 I 0.860
ENSAPLG00000002580 Anas platyrhynchos ENSAPLG00000002580 I 0.860
HNF1A Bos taurus ENSBTAG00000021795 I 0.860
HNF1A Canis familiaris ENSCAFG00000010502 I 0.860
HNF1A Cavia porcellus ENSCPOG00000007242 I 0.860
ENSCSAG00000002227 Chlorocebus sabaeus ENSCSAG00000002227 I 0.860
hnf1ba Danio rerio ENSDARG00000006615 I 0.860
HNF1A Dasypus novemcinctus ENSDNOG00000000374 I 0.860
Hnf1a Dipodomys ordii ENSDORG00000007676 I 0.860
HNF1A Equus caballus ENSECAG00000019954 I 0.860
HNF1B Erinaceus europaeus ENSEEUG00000004998 I 0.860
ENSFALG00000005101 Ficedula albicollis ENSFALG00000005101 I 0.860
ENSFALG00000007499 Ficedula albicollis ENSFALG00000007499 I 0.860
HNF1A Felis catus ENSFCAG00000009638 I 0.860
HNF1A Homo sapiens ENSG00000135100 D 0.860
hnf1ba Gasterosteus aculeatus ENSGACG00000011101 I 0.860
HNF1A Gallus gallus ENSGALG00000006968 I 0.860
HNF1A Gorilla gorilla ENSGGOG00000004329 I 0.860
ENSGMOG00000001038 Gadus morhua ENSGMOG00000001038 I 0.860
ENSGMOG00000016065 Gadus morhua ENSGMOG00000016065 I 0.860
ENSLACG00000012983 Latimeria chalumnae ENSLACG00000012983 I 0.860
ENSLACG00000017915 Latimeria chalumnae ENSLACG00000017915 I 0.860
HNF1A Loxodonta africana ENSLAFG00000017872 I 0.860
ENSLOCG00000002874 Lepisosteus oculatus ENSLOCG00000002874 I 0.860
ENSLOCG00000005942 Lepisosteus oculatus ENSLOCG00000005942 I 0.860
ENSMEUG00000004163 Macropus eugenii ENSMEUG00000004163 I 0.860
HNF1B Meleagris gallopavo ENSMGAG00000008126 I 0.860
HNF1A Meleagris gallopavo ENSMGAG00000008538 I 0.860
HNF1A Myotis lucifugus ENSMLUG00000009109 I 0.860
HNF1A Monodelphis domestica ENSMODG00000002966 I 0.860
ENSMPUG00000003290 Mustela putorius furo ENSMPUG00000003290 I 0.860
HNF1A Ornithorhynchus anatinus ENSOANG00000014646 I 0.860
ENSOARG00000013764 Ovis aries ENSOARG00000013764 I 0.860
HNF1A Otolemur garnettii ENSOGAG00000009071 I 0.860
ENSONIG00000013161 Oreochromis niloticus ENSONIG00000013161 I 0.860
HNF1A Ochotona princeps ENSOPRG00000001671 I 0.860
hnf1ba Oryzias latipes ENSORLG00000004564 I 0.860
ENSPANG00000008728 Papio anubis ENSPANG00000008728 I 0.860
ENSPFOG00000009496 Poecilia formosa ENSPFOG00000009496 I 0.860
ENSPSIG00000013055 Pelodiscus sinensis ENSPSIG00000013055 I 0.860
HNF1A Pan troglodytes ENSPTRG00000005551 I 0.860
HNF1A Pteropus vampyrus ENSPVAG00000008044 I 0.860
Hnf1a Rattus norvegicus ENSRNOG00000001183 I 0.860
HNF1A Sus scrofa ENSSSCG00000009919 I 0.860
ENSSTOG00000004719 Ictidomys tridecemlineatus ENSSTOG00000004719 I 0.860
HNF1A Taeniopygia guttata ENSTGUG00000009673 I 0.860
hnf1ba Tetraodon nigroviridis ENSTNIG00000016225 I 0.860
hnf1ba Takifugu rubripes ENSTRUG00000003809 I 0.860
ENSXMAG00000011775 Xiphophorus maculatus ENSXMAG00000011775 I 0.860
Aan_R008292 Calypte anna Aan_R008292 I 0.860
Afo_R009049 Aptenodytes forsteri Afo_R009049 I 0.860
Alligator_sinensis_CCG014136.1 Alligator sinensis Alligator_sinensis_CCG014136.1 I 0.860
Brh_R011090 Buceros rhinoceros Brh_R011090 I 0.860
Cmyd_10005161 Chelonia mydas Cmyd_10005161 I 0.860
ENSBTAP00000029049-D1 Bos grunniens ENSBTAP00000029049-D1 I 0.860
ENSP00000257555 Macaca fascicularis ENSP00000257555 I 0.860
Gfo_R010877 Geospiza fortis Gfo_R010877 I 0.860
Gfo_R012758 Geospiza fortis Gfo_R012758 I 0.860
Myotis_brandtii_HNF1A_10028127 Myotis brandtii Myotis_brandtii_HNF1A_10028127 I 0.860
Ogr03456 Ophisaurus gracilis Ogr03456 I 0.860
Pvit_03697 Pogona vitticeps Pvit_03697 I 0.860
Tal_R010417 Tyto alba Tal_R010417 I 0.860
hnf1a Xenopus tropicalis XB-GENE-484117 I 0.860
hnf1a.S Xenopus laevis XB-GENE-865049 I 0.860
HNF1B Anolis carolinensis ENSACAG00000006458 I 0.859
ENSAMEG00000013125 Ailuropoda melanoleuca ENSAMEG00000013125 I 0.859
ENSAMXG00000024376 Astyanax mexicanus ENSAMXG00000024376 I 0.859
HNF1B Bos taurus ENSBTAG00000004710 I 0.859
HNF1B Canis familiaris ENSCAFG00000018150 I 0.859
HNF1B Choloepus hoffmanni ENSCHOG00000006010 I 0.859
HNF1B Callithrix jacchus ENSCJAG00000015174 I 0.859
HNF1B Cavia porcellus ENSCPOG00000001234 I 0.859
ENSCSAG00000006125 Chlorocebus sabaeus ENSCSAG00000006125 I 0.859
hnf1bb Danio rerio ENSDARG00000022295 I 0.859
HNF1B Dasypus novemcinctus ENSDNOG00000001586 I 0.859
Hnf1b Dipodomys ordii ENSDORG00000009669 I 0.859
HNF1B Equus caballus ENSECAG00000015854 I 0.859
HNF1B Felis catus ENSFCAG00000000241 I 0.859
HNF1B Homo sapiens ENSG00000275410 D 0.859
HNF1B Gallus gallus ENSGALG00000005504 I 0.859
HNF1B Gorilla gorilla ENSGGOG00000006322 I 0.859
HNF1B Loxodonta africana ENSLAFG00000002573 I 0.859
HNF1B Myotis lucifugus ENSMLUG00000012260 I 0.859
HNF1B Macaca mulatta ENSMMUG00000003431 I 0.859
HNF1B Monodelphis domestica ENSMODG00000019108 I 0.859
ENSMPUG00000015004 Mustela putorius furo ENSMPUG00000015004 I 0.859
Hnf1b Mus musculus ENSMUSG00000020679 D 0.859
ENSNLEG00000002919 Nomascus leucogenys ENSNLEG00000002919 I 0.859
ENSOARG00000003338 Ovis aries ENSOARG00000003338 I 0.859
HNF1B Oryctolagus cuniculus ENSOCUG00000003682 I 0.859
HNF1B Otolemur garnettii ENSOGAG00000000869 I 0.859
HNF1B Ochotona princeps ENSOPRG00000003933 I 0.859
ENSPANG00000022102 Papio anubis ENSPANG00000022102 I 0.859
HNF1B Procavia capensis ENSPCAG00000008147 I 0.859
ENSPPYG00000008222 Pongo abelii ENSPPYG00000008222 I 0.859
ENSPSIG00000009511 Pelodiscus sinensis ENSPSIG00000009511 I 0.859
HNF1B Pan troglodytes ENSPTRG00000009059 I 0.859
HNF1B Pteropus vampyrus ENSPVAG00000010466 I 0.859
Hnf1b Rattus norvegicus ENSRNOG00000002598 I 0.859
HNF1B Sorex araneus ENSSARG00000007152 I 0.859
ENSSHAG00000005052 Sarcophilus harrisii ENSSHAG00000005052 I 0.859
HNF1B Sus scrofa ENSSSCG00000022417 I 0.859
ENSSTOG00000012440 Ictidomys tridecemlineatus ENSSTOG00000012440 I 0.859
ENSTSYG00000010701 Tarsius syrichta ENSTSYG00000010701 I 0.859
HNF1B Tursiops truncatus ENSTTRG00000015910 I 0.859
Aan_R014136 Calypte anna Aan_R014136 I 0.859
Afo_R013605 Aptenodytes forsteri Afo_R013605 I 0.859
Alligator_sinensis_CCG002074.1 Alligator sinensis Alligator_sinensis_CCG002074.1 I 0.859
Cmyd_10016186 Chelonia mydas Cmyd_10016186 I 0.859
ENSBTAP00000006184-D1 Bos grunniens ENSBTAP00000006184-D1 I 0.859
ENSP00000225893 Macaca fascicularis ENSP00000225893 I 0.859
Myotis_brandtii_HNF1B_10031016 Myotis brandtii Myotis_brandtii_HNF1B_10031016 I 0.859
Pvit_13545 Pogona vitticeps Pvit_13545 I 0.859
hnf1b.S Xenopus laevis XB-GENE-17330995 I 0.859
hnf1b Xenopus tropicalis XB-GENE-485652 I 0.859
hnf1b.L Xenopus laevis XB-GENE-485656 I 0.859
XP_002939680 Xenopus tropicalis XP_002939680 I 0.859
fgenesh2_kg.scaffold_157000001 Branchiostoma floridae fgenesh2_kg.scaffold_157000001 I 0.853
fgenesh2_kg.scaffold_214000001 Branchiostoma floridae fgenesh2_kg.scaffold_214000001 I 0.853
Sakowv30011728m.g Saccoglossus kowalevskii Sakowv30011728m.g I 0.849
SPU_010305 Strongylocentrotus purpuratus SPU_010305 I 0.837
SNAPOd2T00002150001 Oikopleura dioica SNAPOd2T00002150001 I 0.837
ENSCSAVG00000009827 Ciona savignyi ENSCSAVG00000009827 I 0.822
ENSCING00000007645 Ciona intestinalis ENSCING00000007645 I 0.821
hnf1a Danio rerio ENSDARG00000009470 I 0.815
ENSONIG00000011178 Oreochromis niloticus ENSONIG00000011178 I 0.815
ENSPFOG00000013053 Poecilia formosa ENSPFOG00000013053 I 0.815
hnf1a Tetraodon nigroviridis ENSTNIG00000011468 I 0.815
hnf1a Takifugu rubripes ENSTRUG00000016222 I 0.815
ENSXMAG00000003472 Xiphophorus maculatus ENSXMAG00000003472 I 0.815
hnf1a Gasterosteus aculeatus ENSGACG00000012691 I 0.803
SPU_008196 Strongylocentrotus purpuratus SPU_008196 N 0.801
ENSORLG00000018971 Oryzias latipes ENSORLG00000018971 I 0.799
TriadG28952 Trichoplax adhaerens TriadG28952 I 0.764
EFV59137 Trichinella spiralis EFV59137 N 0.688
D918_03762 Trichuris suis D918_03762 N 0.688
TTRE_0000607501 Trichuris trichiura TTRE_0000607501 N 0.688
ENSAMXG00000011241 Astyanax mexicanus ENSAMXG00000011241 I 0.683
zgc:91944 Danio rerio ENSDARG00000035887 I 0.683
zgc:91944 Gasterosteus aculeatus ENSGACG00000009223 I 0.683
ENSGMOG00000004622 Gadus morhua ENSGMOG00000004622 I 0.683
ENSONIG00000007704 Oreochromis niloticus ENSONIG00000007704 I 0.683
zgc:91944 Oryzias latipes ENSORLG00000020883 I 0.683
ENSPFOG00000012263 Poecilia formosa ENSPFOG00000012263 I 0.683
zgc:91944 Tetraodon nigroviridis ENSTNIG00000014025 I 0.683
zgc:91944 Takifugu rubripes ENSTRUG00000012550 I 0.683
ENSXMAG00000005730 Xiphophorus maculatus ENSXMAG00000005730 I 0.683
SPU_002791 Strongylocentrotus purpuratus SPU_002791 I 0.675
SPU_022737 Strongylocentrotus purpuratus SPU_022737 I 0.675
Hmbox1 Dipodomys ordii ENSDORG00000015971 N 0.656
HMBOX1 Homo sapiens ENSG00000147421 D 0.656
ENSLACG00000003225 Latimeria chalumnae ENSLACG00000003225 N 0.656
HMBOX1 Microcebus murinus ENSMICG00000010422 N 0.656
Hmbox1 Mus musculus ENSMUSG00000021972 D 0.656
HMBOX1 Ochotona princeps ENSOPRG00000013613 N 0.656
HMBOX1 Sorex araneus ENSSARG00000009365 N 0.656
Ogr07758 Ophisaurus gracilis Ogr07758 N 0.656
HMBOX1 Anolis carolinensis ENSACAG00000010160 I 0.638
ENSAMEG00000016028 Ailuropoda melanoleuca ENSAMEG00000016028 I 0.638
ENSAMXG00000018539 Astyanax mexicanus ENSAMXG00000018539 I 0.638
ENSAPLG00000006003 Anas platyrhynchos ENSAPLG00000006003 I 0.638
HMBOX1 Bos taurus ENSBTAG00000010819 I 0.638
HMBOX1 Canis familiaris ENSCAFG00000008237 I 0.638
HMBOX1 Choloepus hoffmanni ENSCHOG00000005538 I 0.638
HMBOX1 Callithrix jacchus ENSCJAG00000015654 I 0.638
HMBOX1 Cavia porcellus ENSCPOG00000011124 I 0.638
ENSCSAG00000015894 Chlorocebus sabaeus ENSCSAG00000015894 I 0.638
hmbox1b Danio rerio ENSDARG00000018913 I 0.638
hmbox1a Danio rerio ENSDARG00000027082 I 0.638
HMBOX1 Dasypus novemcinctus ENSDNOG00000031840 I 0.638
HMBOX1 Equus caballus ENSECAG00000008240 I 0.638
ENSFALG00000010859 Ficedula albicollis ENSFALG00000010859 I 0.638
HMBOX1 Felis catus ENSFCAG00000022672 I 0.638
hmbox1b Gasterosteus aculeatus ENSGACG00000004391 I 0.638
HMBOX1 Gallus gallus ENSGALG00000016633 I 0.638
HMBOX1 Gorilla gorilla ENSGGOG00000000860 I 0.638
ENSGMOG00000002742 Gadus morhua ENSGMOG00000002742 I 0.638
ENSGMOG00000006872 Gadus morhua ENSGMOG00000006872 I 0.638
ENSLACG00000011304 Latimeria chalumnae ENSLACG00000011304 I 0.638
HMBOX1 Loxodonta africana ENSLAFG00000032318 I 0.638
ENSLOCG00000001916 Lepisosteus oculatus ENSLOCG00000001916 I 0.638
ENSLOCG00000015994 Lepisosteus oculatus ENSLOCG00000015994 I 0.638
ENSMEUG00000015023 Macropus eugenii ENSMEUG00000015023 I 0.638
HMBOX1 Myotis lucifugus ENSMLUG00000007478 I 0.638
HMBOX1 Macaca mulatta ENSMMUG00000014981 I 0.638
HMBOX1 Monodelphis domestica ENSMODG00000008788 I 0.638
ENSMPUG00000001070 Mustela putorius furo ENSMPUG00000001070 I 0.638
ENSNLEG00000016701 Nomascus leucogenys ENSNLEG00000016701 I 0.638
ENSOARG00000015036 Ovis aries ENSOARG00000015036 I 0.638
HMBOX1 Oryctolagus cuniculus ENSOCUG00000017211 I 0.638
HMBOX1 Otolemur garnettii ENSOGAG00000001381 I 0.638
ENSONIG00000001328 Oreochromis niloticus ENSONIG00000001328 I 0.638
hmbox1b Oryzias latipes ENSORLG00000016242 I 0.638
ENSPANG00000014537 Papio anubis ENSPANG00000014537 I 0.638
HMBOX1 Procavia capensis ENSPCAG00000012005 I 0.638
ENSPFOG00000000843 Poecilia formosa ENSPFOG00000000843 I 0.638
ENSPPYG00000018480 Pongo abelii ENSPPYG00000018480 I 0.638
ENSPSIG00000016826 Pelodiscus sinensis ENSPSIG00000016826 I 0.638
HMBOX1 Pan troglodytes ENSPTRG00000020127 I 0.638
Hmbox1 Rattus norvegicus ENSRNOG00000013326 I 0.638
ENSSHAG00000016211 Sarcophilus harrisii ENSSHAG00000016211 I 0.638
HMBOX1 Sus scrofa ENSSSCG00000009682 I 0.638
HMBOX1 Taeniopygia guttata ENSTGUG00000013324 I 0.638
hmbox1b Takifugu rubripes ENSTRUG00000004378 I 0.638
ENSTSYG00000001109 Tarsius syrichta ENSTSYG00000001109 I 0.638
HMBOX1 Tursiops truncatus ENSTTRG00000015467 I 0.638
ENSXMAG00000001795 Xiphophorus maculatus ENSXMAG00000001795 I 0.638
Aan_R010756 Calypte anna Aan_R010756 I 0.638
Afo_R011837 Aptenodytes forsteri Afo_R011837 I 0.638
Brh_R012838 Buceros rhinoceros Brh_R012838 I 0.638
Cmyd_10005786 Chelonia mydas Cmyd_10005786 I 0.638
ENSP00000401769-D1 Bos grunniens ENSP00000401769-D1 I 0.638
ENSP00000401769 Macaca fascicularis ENSP00000401769 I 0.638
Gfo_R008926 Geospiza fortis Gfo_R008926 I 0.638
Myotis_brandtii_HMBOX1_10012332 Myotis brandtii Myotis_brandtii_HMBOX1_10012332 I 0.638
hmbox1.S Xenopus laevis XB-GENE-6078482 I 0.638
CapteG124171 Capitella teleta CapteG124171 I 0.631
HelroG166133 Helobdella robusta HelroG166133 I 0.631