CIS-BP Database: Catalog of Inferred Sequence Binding Preferences

TF Information

ISCW024267 *(Ixodes scapularis)* Homeodomain
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF00046 (Homeobox)	IPR001356	ISCW024267	T219754_2.00	Ensembl (2018-Dec-8)	Link out
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
CG11085 M03857_2.00	Drosophila melanogaster	BTAAWYGN	NCRWTTAV	SELEX Nitta et al.(2015) CG11085_1	0.674	0.788
CG11085 M03858_2.00	Drosophila melanogaster	NTAAWCGN	NCGWTTAN	SELEX Nitta et al.(2015) CG11085_2	0.674	0.788
CG11085 M06532_2.00	Drosophila melanogaster	TTAATDG	CHATTAA	B1H Mathelier et al.(2014) MA0171.1	0.674	0.788
CG11085 M06339_2.00	Drosophila melanogaster	NTTAATDGV	BCHATTAAN	B1H Zhu et al.(2011) CG11085_Cell_FBgn0030408	0.674	0.788
CG11085 M06340_2.00	Drosophila melanogaster	NHTAAWBRNN	NNYVWTTADN	B1H Zhu et al.(2011) CG11085_SOLEXA_FBgn0030408	0.674	0.788
Gbx2 M00462_2.00	Mus musculus	NNDAHNN	NNDTHNN	PBM Berger et al.(2008) Gbx2_3110	0.637	0.596
Gbx1 M00525_2.00	Mus musculus	NNTAATNR	YNATTANN	PBM Berger et al.(2008) Gbx1_2883	0.637	0.596
GBX1 M03193_2.00	Homo sapiens	NBTAATTRSB	VSYAATTAVN	SELEX Jolma et al.(2013) GBX1_1	0.637	0.596
GBX2 M03201_2.00	Homo sapiens	NNTAATTRNN	NNYAATTANN	SELEX Jolma et al.(2013) GBX2_1	0.637	0.596
GBX2 M03202_2.00	Homo sapiens	TAATTRVBCAATWA	TWATTGVBYAATTA	SELEX Jolma et al.(2013) GBX2_2	0.637	0.596
GBX2 M03203_2.00	Homo sapiens	NNTAATTRNN	NNYAATTANN	SELEX Jolma et al.(2013) GBX2_3	0.637	0.596
Gbx1 M03286_2.00	Mus musculus	NNTAATTRNN	NNYAATTANN	SELEX Jolma et al.(2013) Gbx1_1	0.637	0.596
Gbx2 M03268_2.00	Mus musculus	NNTAATTRNN	NNYAATTANN	SELEX Jolma et al.(2013) Gbx2_1	0.637	0.596
GBX2 M05265_2.00	Homo sapiens	NTAATTRN	NYAATTAN	SELEX Yin et al.(2017) GBX2_eDBD_HT-SELEX	0.637	0.596
GBX2 M05268_2.00	Homo sapiens	NTAATTRV	BYAATTAN	SELEX Yin et al.(2017) GBX2_FL_HT-SELEX	0.637	0.596
GBX2 M05266_2.00	Homo sapiens	HTAAYGAB	VTCRTTAD	SELEX Yin et al.(2017) GBX2_eDBD_Methyl-HT-SELEX_1	0.637	0.596
GBX2 M05267_2.00	Homo sapiens	NTAATTRN	NYAATTAN	SELEX Yin et al.(2017) GBX2_eDBD_Methyl-HT-SELEX_2	0.637	0.596
GBX2 M05269_2.00	Homo sapiens	NTAATTRN	NYAATTAN	SELEX Yin et al.(2017) GBX2_FL_Methyl-HT-SELEX_1	0.637	0.596
GBX2 M05270_2.00	Homo sapiens	NTAAYGAB	VTCRTTAN	SELEX Yin et al.(2017) GBX2_FL_Methyl-HT-SELEX_2	0.637	0.596
unpg M03836_2.00	Drosophila melanogaster	SSTAATYRVN	NBYRATTASS	SELEX Nitta et al.(2015) unpg_1	0.625	0.577
unpg M06517_2.00	Drosophila melanogaster	BTAATTR	YAATTAV	B1H Mathelier et al.(2014) MA0251.1	0.625	0.577
unpg M06311_2.00	Drosophila melanogaster	NBTAATTR	YAATTAVN	B1H Zhu et al.(2011) Unpg_Cell_FBgn0015561	0.625	0.577
unpg M06312_2.00	Drosophila melanogaster	HTAATTR	YAATTAD	B1H Zhu et al.(2011) Unpg_SOLEXA_FBgn0015561	0.625	0.577
Nkx1-2 M00503_2.00	Mus musculus	NNTAAWNDN	NHNWTTANN	PBM Berger et al.(2008) Nkx1-2_3214	0.622	0.654
Nkx1-1 M00442_2.00	Mus musculus	NNTAATNDNN	NNHNATTANN	PBM Berger et al.(2008) Nkx1-1_3856	0.621	0.635
slou M00557_2.00	Drosophila melanogaster	NNTAATDRN	NYHATTANN	PBM Busser et al.(2012a) Slou	0.621	0.635
slou M03798_2.00	Drosophila melanogaster	VBTAATTRSB	VSYAATTAVB	SELEX Nitta et al.(2015) slou_1	0.621	0.635
slou M06494_2.00	Drosophila melanogaster	YTAATKR	YMATTAR	B1H Mathelier et al.(2014) MA0245.1	0.621	0.635
slou M06262_2.00	Drosophila melanogaster	BYTAATKR	YMATTARV	B1H Zhu et al.(2011) Slou_Cell_FBgn0002941	0.621	0.635
slou M06263_2.00	Drosophila melanogaster	HTAATKR	YMATTAD	B1H Zhu et al.(2011) Slou_SOLEXA_FBgn0002941	0.621	0.635
Mnx1 M00388_2.00	Mus musculus	NTAATBDNNN	NNNHVATTAN	PBM Berger et al.(2008) Hlxb9_3422	0.621	0.615
MNX1 M03143_2.00	Homo sapiens	NHTAATTRNH	DNYAATTADN	SELEX Jolma et al.(2013) MNX1_1	0.621	0.615
MNX1 M05126_2.00	Homo sapiens	NTAATTRN	NYAATTAN	SELEX Yin et al.(2017) MNX1_eDBD_HT-SELEX	0.621	0.615
MNX1 M05127_2.00	Homo sapiens	HTAAYGHB	VDCRTTAD	SELEX Yin et al.(2017) MNX1_eDBD_Methyl-HT-SELEX_1	0.621	0.615
MNX1 M05128_2.00	Homo sapiens	NTAATTRN	NYAATTAN	SELEX Yin et al.(2017) MNX1_eDBD_Methyl-HT-SELEX_2	0.621	0.615
exex M03871_2.00	Drosophila melanogaster	NNNNYAATTNNYDN	NHRNNAATTRNNNN	SELEX Nitta et al.(2015) exex_1	0.621	0.596
exex M06544_2.00	Drosophila melanogaster	BTAATTA	TAATTAV	B1H Mathelier et al.(2014) MA0224.1	0.621	0.596
exex M06364_2.00	Drosophila melanogaster	TAATTAV	BTAATTA	B1H Zhu et al.(2011) Exex_Cell_FBgn0041156	0.621	0.596
exex M06365_2.00	Drosophila melanogaster	TAATBR	YVATTA	B1H Zhu et al.(2011) Exex_SOLEXA_FBgn0041156	0.621	0.596
Barhl2 M00460_2.00	Mus musculus	NTAAWNRNN	NNYNWTTAN	PBM Berger et al.(2008) Barhl2_3868	0.617	0.654
BARHL2 M03157_2.00	Homo sapiens	NNTAAWYGNN	NNCRWTTANN	SELEX Jolma et al.(2013) BARHL2_1	0.617	0.654
BARHL2 M03158_2.00	Homo sapiens	NNTAAWBGNN	NNCVWTTANN	SELEX Jolma et al.(2013) BARHL2_2	0.617	0.654
BARHL2 M03159_2.00	Homo sapiens	TAAWYGNNNNTAAWYR	YRWTTANNNNCRWTTA	SELEX Jolma et al.(2013) BARHL2_3	0.617	0.654
BARHL2 M03160_2.00	Homo sapiens	NNTAAWYGNH	DNCRWTTANN	SELEX Jolma et al.(2013) BARHL2_4	0.617	0.654
BARHL2 M03161_2.00	Homo sapiens	NNTAAWYGNN	NNCRWTTANN	SELEX Jolma et al.(2013) BARHL2_5	0.617	0.654
BARHL2 M03162_2.00	Homo sapiens	TAAWYGNYNHTAAWYG	CRWTTADNRNCRWTTA	SELEX Jolma et al.(2013) BARHL2_6	0.617	0.654
BARHL2 M05164_2.00	Homo sapiens	HTAAAYGNY	RNCRTTTAD	SELEX Yin et al.(2017) BARHL2_eDBD_HT-SELEX_1	0.617	0.654
BARHL2 M05165_2.00	Homo sapiens	NTAAWTGNB	VNCAWTTAN	SELEX Yin et al.(2017) BARHL2_eDBD_HT-SELEX_2	0.617	0.654
BARHL2 M05167_2.00	Homo sapiens	NTAAWYGN	NCRWTTAN	SELEX Yin et al.(2017) BARHL2_FL_HT-SELEX_1	0.617	0.654
BARHL2 M05168_2.00	Homo sapiens	NTAAWYGN	NCRWTTAN	SELEX Yin et al.(2017) BARHL2_FL_HT-SELEX_2	0.617	0.654
BARHL2 M05166_2.00	Homo sapiens	NTAAWTGNB	VNCAWTTAN	SELEX Yin et al.(2017) BARHL2_eDBD_Methyl-HT-SELEX	0.617	0.654
BARHL2 M05169_2.00	Homo sapiens	NTAAWTGN	NCAWTTAN	SELEX Yin et al.(2017) BARHL2_FL_Methyl-HT-SELEX	0.617	0.654
ENSTNIG00000006040 M02106_2.00	Tetraodon nigroviridis	NNNBTAAWHRBNN	NNVYDWTTAVNNN	PBM Weirauch et al.(2014) pTH6503	0.617	0.615
HOXA2 M02083_2.00	Homo sapiens	NNNDHHNNN	NNNDDHNNN	PBM Weirauch et al.(2014) pTH5887	0.616	0.538
Hoxa2 M00403_2.00	Mus musculus	NTAATKRNN	NNYMATTAN	PBM Berger et al.(2008) Hoxa2_3079	0.616	0.538
HOXA2 M03097_2.00	Homo sapiens	NBTAATKRNN	NNYMATTAVN	SELEX Jolma et al.(2013) HOXA2_1	0.616	0.538
HOXB2 M03213_2.00	Homo sapiens	NNTAATKRNN	NNYMATTANN	SELEX Jolma et al.(2013) HOXB2_1	0.616	0.538
Hoxa2 M03251_2.00	Mus musculus	NNTAATKRNN	NNYMATTANN	SELEX Jolma et al.(2013) Hoxa2_1	0.616	0.538
pb M03872_2.00	Drosophila melanogaster	NTRAYKRY	RYMRTYAN	SELEX Nitta et al.(2015) pb_1	0.616	0.538
HOXA2 M04962_2.00	Homo sapiens	NTAATKRV	BYMATTAN	SELEX Yin et al.(2017) HOXA2_eDBD_HT-SELEX	0.616	0.538
HOXA2 M04965_2.00	Homo sapiens	NTAATKAB	VTMATTAN	SELEX Yin et al.(2017) HOXA2_FL_HT-SELEX	0.616	0.538
HOXB2 M05292_2.00	Homo sapiens	BTAATKRV	BYMATTAV	SELEX Yin et al.(2017) HOXB2_eDBD_HT-SELEX	0.616	0.538
pb M06545_2.00	Drosophila melanogaster	YTAATKA	TMATTAR	B1H Mathelier et al.(2014) MA0238.1	0.616	0.538
pb M06366_2.00	Drosophila melanogaster	BYTAATKA	TMATTARV	B1H Zhu et al.(2011) Pb_Cell_FBgn0051481	0.616	0.538
pb M06367_2.00	Drosophila melanogaster	YTAATKA	TMATTAR	B1H Zhu et al.(2011) Pb_SOLEXA_FBgn0051481	0.616	0.538
Hoxa2 M09566_2.00	Mus musculus	DTGATKGATKDB	VHMATCMATCAH	Misc Heinz et al.(2010) mES-Hoxa2_Donaldson_et_al.	0.616	0.538
HOXA2 M04963_2.00	Homo sapiens	NTAATTAN	NTAATTAN	SELEX Yin et al.(2017) HOXA2_eDBD_Methyl-HT-SELEX_1	0.616	0.538
HOXA2 M04964_2.00	Homo sapiens	HTAAYGAB	VTCRTTAD	SELEX Yin et al.(2017) HOXA2_eDBD_Methyl-HT-SELEX_2	0.616	0.538
HOXA2 M04966_2.00	Homo sapiens	NTAATKAB	VTMATTAN	SELEX Yin et al.(2017) HOXA2_FL_Methyl-HT-SELEX_1	0.616	0.538
HOXA2 M04967_2.00	Homo sapiens	HTAAYGAB	VTCRTTAD	SELEX Yin et al.(2017) HOXA2_FL_Methyl-HT-SELEX_2	0.616	0.538
HOXB2 M05293_2.00	Homo sapiens	NTAATKRN	NYMATTAN	SELEX Yin et al.(2017) HOXB2_eDBD_Methyl-HT-SELEX_1	0.616	0.538
HOXB2 M05294_2.00	Homo sapiens	HTAAYGAB	VTCRTTAD	SELEX Yin et al.(2017) HOXB2_eDBD_Methyl-HT-SELEX_2	0.616	0.538
Barx2 M00457_2.00	Mus musculus	NTAABNDNN	NNHNVTTAN	PBM Berger et al.(2008) Barx2_3447	0.615	0.635
BARX2 M04915_2.00	Homo sapiens	NTAAYKRTTWWN	NWWAAYMRTTAN	SELEX Yin et al.(2017) BARX2_FL_HT-SELEX	0.615	0.635
BARX2 M04916_2.00	Homo sapiens	NTAAYKRTTWWN	NWWAAYMRTTAN	SELEX Yin et al.(2017) BARX2_FL_Methyl-HT-SELEX	0.615	0.635
Barx1 M00413_2.00	Mus musculus	NNTAAYBDNN	NNHVRTTANN	PBM Berger et al.(2008) Barx1_2877	0.615	0.615
barx1 M02107_2.00	Tetraodon nigroviridis	NTAAYNNNN	NNNNRTTAN	PBM Weirauch et al.(2014) pTH6449	0.615	0.615
BARX1 M03144_2.00	Homo sapiens	TAATBGNWWWTTAATBR	YVATTAAWWWNCVATTA	SELEX Jolma et al.(2013) BARX1_1	0.615	0.615
BARX1 M03145_2.00	Homo sapiens	NTAATBRN	NYVATTAN	SELEX Jolma et al.(2013) BARX1_2	0.615	0.615
Barx1 M09181_2.00	Mus musculus	NNWAAKKGYTWH	DWARCMMTTWNN	Misc Kulakovskiy et al.(2013) BARX1_MOUSE.H11MO.0.C	0.615	0.615
eve M00556_2.00	Drosophila melanogaster	NNTAATTARN	NYTAATTANN	PBM Busser et al.(2012a) Eve	0.611	0.481
eve M02115_2.00	Drosophila melanogaster	NTAATNDNN	NNHNATTAN	PBM Weirauch et al.(2014) pTH6436	0.611	0.481
eve M03794_2.00	Drosophila melanogaster	VYTAATKASN	NSTMATTARB	SELEX Nitta et al.(2015) eve_1	0.611	0.481
eve M06486_2.00	Drosophila melanogaster	YTAATKA	TMATTAR	B1H Mathelier et al.(2014) MA0221.1	0.611	0.481
eve M06240_2.00	Drosophila melanogaster	DYTAATKA	TMATTARH	B1H Zhu et al.(2011) Eve_Cell_FBgn0000606	0.611	0.481
eve M06241_2.00	Drosophila melanogaster	HKBTAAYNDTKY	RMAHNRTTAVMD	B1H Zhu et al.(2011) eve_FlyReg_FBgn0000606	0.611	0.481
eve M06242_2.00	Drosophila melanogaster	NYTAATKA	TMATTARN	B1H Zhu et al.(2011) Eve_SOLEXA_FBgn0000606	0.611	0.481
eve M09678_2.00	Drosophila melanogaster	NKHTAATKD	HMATTADMN	Misc Kulakovskiy et al.(2009) eve	0.611	0.481
eve M10786_2.00	Drosophila melanogaster	Transfac license required	Transfac license required	Transfac Matys et al.(2006) I$EVE_Q6	0.611	0.481
Barhl1 M00433_2.00	Mus musculus	NTAAWNRNN	NNYNWTTAN	PBM Berger et al.(2008) Barhl1_2590	0.607	0.673
Barhl1 M03258_2.00	Mus musculus	NNTAAWYGNH	DNCRWTTANN	SELEX Jolma et al.(2013) Barhl1_1	0.607	0.673
Barhl1 M03259_2.00	Mus musculus	NNTAADNRNN	NNYNHTTANN	SELEX Jolma et al.(2013) Barhl1_2	0.607	0.673
Barhl1 M03260_2.00	Mus musculus	TAAWYGNYNNTAAWYG	CRWTTANNRNCRWTTA	SELEX Jolma et al.(2013) Barhl1_3	0.607	0.673
BARHL1 M05091_2.00	Homo sapiens	NTAAWYGN	NCRWTTAN	SELEX Yin et al.(2017) BARHL1_eDBD_HT-SELEX_1	0.607	0.673
BARHL1 M05092_2.00	Homo sapiens	NTAADBGN	NCVHTTAN	SELEX Yin et al.(2017) BARHL1_eDBD_HT-SELEX_2	0.607	0.673
BARHL1 M05093_2.00	Homo sapiens	NTAADKGN	NCMHTTAN	SELEX Yin et al.(2017) BARHL1_eDBD_Methyl-HT-SELEX	0.607	0.673
B-H2 M03810_2.00	Drosophila melanogaster	VNTAAAYGNH	DNCRTTTANB	SELEX Nitta et al.(2015) B-H2_1	0.606	0.615
B-H2 M03811_2.00	Drosophila melanogaster	SNTAADBGN	NCVHTTANS	SELEX Nitta et al.(2015) B-H2_2	0.606	0.615
B-H2 M06503_2.00	Drosophila melanogaster	WTAATTG	CAATTAW	B1H Mathelier et al.(2014) MA0169.1	0.606	0.615
B-H1 M03829_2.00	Drosophila melanogaster	VNTAAWYGNN	NNCRWTTANB	SELEX Nitta et al.(2015) B-H1_1	0.606	0.596
B-H1 M03830_2.00	Drosophila melanogaster	SNTAADBGN	NCVHTTANS	SELEX Nitta et al.(2015) B-H1_2	0.606	0.596
B-H1 M06512_2.00	Drosophila melanogaster	HTAAWYG	CRWTTAD	B1H Mathelier et al.(2014) MA0168.1	0.606	0.596
ESX1 M00292_2.00	Homo sapiens	NNTAATNDN	NHNATTANN	PBM Barrera et al.(2016) ESX1_REF	0.600	0.558
ESX1 M03137_2.00	Homo sapiens	NNTAATTRNN	NNYAATTANN	SELEX Jolma et al.(2013) ESX1_1	0.600	0.558
ESX1 M03138_2.00	Homo sapiens	NNTAATTRNN	NNYAATTANN	SELEX Jolma et al.(2013) ESX1_2	0.600	0.558
ESX1 M05087_2.00	Homo sapiens	NTAATTRV	BYAATTAN	SELEX Yin et al.(2017) ESX1_eDBD_HT-SELEX	0.600	0.558
ESX1 M05089_2.00	Homo sapiens	NTAATTRV	BYAATTAN	SELEX Yin et al.(2017) ESX1_FL_HT-SELEX	0.600	0.558
ESX1 M00291_2.00	Homo sapiens	NNTRATNRN	NYNATYANN	PBM Barrera et al.(2016) ESX1_K193R	0.600	0.558
ESX1 M05088_2.00	Homo sapiens	NTAATTRR	YYAATTAN	SELEX Yin et al.(2017) ESX1_eDBD_Methyl-HT-SELEX	0.600	0.558
ESX1 M05090_2.00	Homo sapiens	NTAATTRR	YYAATTAN	SELEX Yin et al.(2017) ESX1_FL_Methyl-HT-SELEX	0.600	0.558
For this family, TFs with SR scores > 0.599* will likely have a similar motif*

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
ISCW024267-PA	Homeodomain	24	75	RRRRTAFTQSQLAFLENKFRYQKYLSVSDRGSVAEALHLTETQVKTWYQNRR

Links
Other Homeodomain family TFs
Other *Ixodes scapularis* TFs

1373 Related TFs

Name	Species	Gene ID	Motif Evidence	SR Score	Action
ENSAMEG00000006680	Ailuropoda melanoleuca	ENSAMEG00000006680	I
ZNF12	Bos taurus	ENSBTAG00000039782	I
ZNF12	Canis familiaris	ENSCAFG00000015948	I
ZNF12	Choloepus hoffmanni	ENSCHOG00000013201	I
ZNF12	Callithrix jacchus	ENSCJAG00000015557	I
ENSCSAG00000017682	Chlorocebus sabaeus	ENSCSAG00000017682	I
ZNF12	Dasypus novemcinctus	ENSDNOG00000037946	I
Zfp12	Dipodomys ordii	ENSDORG00000005742	I
ZNF12	Equus caballus	ENSECAG00000016420	I
ZNF12	Felis catus	ENSFCAG00000008342	I
ZNF12	Homo sapiens	ENSG00000164631	D
ZNF12	Microcebus murinus	ENSMICG00000008171	I
ZNF12	Macaca mulatta	ENSMMUG00000012343	I
ENSMPUG00000016596	Mustela putorius furo	ENSMPUG00000016596	I
Zfp12	Mus musculus	ENSMUSG00000029587	I
ENSNLEG00000015586	Nomascus leucogenys	ENSNLEG00000015586	I
ENSOARG00000002550	Ovis aries	ENSOARG00000002550	I
ZNF12	Oryctolagus cuniculus	ENSOCUG00000008958	I
ZNF12	Otolemur garnettii	ENSOGAG00000028373	I
ENSP00000409597-D73	Bos grunniens	ENSP00000409597-D73	I
ENSPANG00000021731	Papio anubis	ENSPANG00000021731	I
ENSPPYG00000017356	Pongo abelii	ENSPPYG00000017356	I
ZNF12	Pan troglodytes	ENSPTRG00000018919	I
ZNF84	Pteropus vampyrus	ENSPVAG00000001565	I
Zfp12	Rattus norvegicus	ENSRNOG00000006958	I
ZNF12	Sorex araneus	ENSSARG00000012430	I
ENSSSCG00000030445	Sus scrofa	ENSSSCG00000030445	I
ENSSTOG00000022132	Ictidomys tridecemlineatus	ENSSTOG00000022132	I
ENSTSYG00000010296	Tarsius syrichta	ENSTSYG00000010296	I
ZNF12	Tursiops truncatus	ENSTTRG00000005007	I
Myotis_brandtii_ZNF12_10024232	Myotis brandtii	Myotis_brandtii_ZNF12_10024232	I

ISCW024267 (Ixodes scapularis) Homeodomain

TF Information

Directly determined binding motifs

Motifs from related TFs

DNA Binding Domains

Links

1373 Related TFs

ISCW024267 **(Ixodes scapularis)
Homeodomain**