CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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pax-1
(
Caenorhabditis elegans
)
Paired box
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00292 (PAX)
IPR001523
WBGene00003937
T312107_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure development and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in epithelial cell and pharyngeal cell. Human ortholog(s) of this gene implicated in branchiootorenal syndrome and tooth agenesis. Orthologous to several human genes including PAX9 (paired box 9). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
No direct experiments
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
Poxm
M03944_2.00
Drosophila melanogaster
CAVTCAWGCGTGACR
YGTCACGCWTGABTG
SELEX
Nitta et al.(2015)
Poxm_1
0.752
0.752
Poxm
M03945_2.00
Drosophila melanogaster
NYSAWGCRTRACS
SGTYAYGCWTSRN
SELEX
Nitta et al.(2015)
Poxm_2
0.752
0.752
Poxm
M06436_2.00
Drosophila melanogaster
NNNNNNMVNHNRNSCRTGA
TCAYGSNYNDNBKNNNNNN
B1H
Zhu et al.(2011)
Poxm_SOLEXA_5_FBgn0003129
0.752
0.752
pax9
M11204_2.00
Danio rerio
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$PAX9_B
0.712
0.712
PAX1
M03442_2.00
Homo sapiens
DBCANTSAWGCGTGACS
SGTCACGCWTSANTGVH
SELEX
Jolma et al.(2013)
PAX1_1
0.704
0.704
PAX9
M03444_2.00
Homo sapiens
NKCANTSAWGCGTGACS
SGTCACGCWTSANTGMN
SELEX
Jolma et al.(2013)
PAX9_1
0.704
0.704
PAX1
M05687_2.00
Homo sapiens
BCRNTSRWGCGTGACSN
NSGTCACGCWYSANYGV
SELEX
Yin et al.(2017)
PAX1_eDBD_HT-SELEX
0.704
0.704
PAX9
M05689_2.00
Homo sapiens
BHRNYSRDSCGTRACSN
NSGTYACGSHYSRNYDV
SELEX
Yin et al.(2017)
PAX9_eDBD_HT-SELEX
0.704
0.704
PAX1
M11207_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$PAX1_B
0.704
0.704
PAX1
M05688_2.00
Homo sapiens
BCRNTSAWGCGTGACSN
NSGTCACGCWTSANYGV
SELEX
Yin et al.(2017)
PAX1_eDBD_Methyl-HT-SELEX
0.704
0.704
PAX9
M05690_2.00
Homo sapiens
BCRNTSAWSCGYGACNN
NNGTCRCGSWTSANYGV
SELEX
Yin et al.(2017)
PAX9_eDBD_Methyl-HT-SELEX
0.704
0.704
For this family, TFs with SR scores >
0.700
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
K07C11.1
Paired box
61
185
KTAEVNQLGGVFVNGRPLPFEMRCKIVELSRQGTRPCDISRQLKISHGCVSKILTRFSENGTIMPGTIGGSRPRVTTPKVVEYIRSLKRSDPGIFAWEIRDRLISADICDRANLPSVSSISRILR
Links
Other
Paired box
family TFs
Other
Caenorhabditis elegans
TFs
221 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy