SMAD1 (Homo sapiens)
SMAD

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF03165 (MH1) IPR003619 ENSG00000170365 T324630_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
SMAD1
M11286_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD1_01		 (Direct) (Direct)
SMAD1
M11287_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD1_Q6		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Smad5
M11288_2.00 		Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD5_01 		0.974 0.974
SMAD5
M05743_2.00 		Homo sapiens
YGTCTAGACW
WGTCTAGACR		 SELEX
Yin et al.(2017)
SMAD5_eDBD_HT-SELEX 		0.966 0.966
Smad5
M11292_2.00 		Rattus norvegicus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD5_03 		0.974 0.974
SMAD9
M11274_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD8_01 		0.948 0.948
SMAD5
M11271_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD5_02 		0.966 0.966
Smad9
M11290_2.00 		Rattus norvegicus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD8_02 		0.939 0.939
Smad9
M11289_2.00 		Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD8_03 		0.951 0.951
SMAD5
M11272_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD5_Q5_01 		0.966 0.966
Mad
M06446_2.00 		Drosophila melanogaster
GYGHCGBCVS
SBGVCGDCRC		 B1H
Zhu et al.(2011)
Mad_FlyReg_FBgn0011648 		0.924 0.924
SMAD5
M11273_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD5_Q5 		0.966 0.966
Mad
M08427_2.00 		Drosophila melanogaster
SNGRCGMSRVSRBNS
SNVYSBYSKCGYCNS		 ChIP-chip
Mathelier et al.(2014)
MA0535.1 		0.924 0.924
SMAD5
M05744_2.00 		Homo sapiens
CGTCTAGACR
YGTCTAGACG		 SELEX
Yin et al.(2017)
SMAD5_eDBD_Methyl-HT-SELEX 		0.966 0.966
Mad
M09692_2.00 		Drosophila melanogaster
KCBGSHGKCGCSNC
GNSGCGMCDSCVGM		 Misc
Kulakovskiy et al.(2009)
Mad 		0.924 0.924
Mad
M11293_2.00 		Drosophila melanogaster Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
I$MAD_Q6 		0.935 0.935
Smad3
M00192_2.00 		Mus musculus
NNNNNMGMCN
NGKCKNNNNN		 PBM
Badis et al.(2009)
Smad3_3805 		0.701 0.701
SMAD3
M03482_2.00 		Homo sapiens
YGTCTAGACA
TGTCTAGACR		 SELEX
Jolma et al.(2013)
SMAD3_1 		0.701 0.701
SMAD3
M09380_2.00 		Homo sapiens
NBCTSHCWSCWB
VWGSWGDSAGVN		 Misc
Kulakovskiy et al.(2013)
SMAD3_HUMAN.H11MO.0.B 		0.701 0.701
Smad3
M09384_2.00 		Mus musculus
NBCTSHCWSCWB
VWGSWGDSAGVN		 Misc
Kulakovskiy et al.(2013)
SMAD3_MOUSE.H11MO.0.B 		0.701 0.701
Smad3
M09637_2.00 		Mus musculus
BYAGMCWN
NWGKCTRV		 Misc
Heinz et al.(2010)
NPC-Smad3_GSE36673 		0.701 0.701
SMAD3
M11283_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD3_Q6_01 		0.701 0.701
SMAD3
M11284_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD3_Q6_02 		0.701 0.701
SMAD3
M11285_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD3_Q6 		0.701 0.701
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000305769 SMAD 30 131
ENSP00000377652 SMAD 30 131
ENSP00000422706 SMAD 30 58
ENSP00000424649 SMAD 30 95
ENSP00000424959 SMAD 30 106
ENSP00000425270 SMAD 30 112
ENSP00000426568 SMAD 30 131
ENSP00000427002 SMAD 30 131

Links

Other SMAD family TFs
Other Homo sapiens TFs

462 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
AAI70264 Xenopus laevis AAI70264 N
Aan_R012927 Calypte anna Aan_R012927 N
Afo_R001804 Aptenodytes forsteri Afo_R001804 N
Afo_R010888 Aptenodytes forsteri Afo_R010888 N
Brh_R002741 Buceros rhinoceros Brh_R002741 N
MYT1L Anolis carolinensis ENSACAG00000005667 N
MYT1 Anolis carolinensis ENSACAG00000006249 N
ST18 Anolis carolinensis ENSACAG00000017961 N
ENSAMEG00000002048 Ailuropoda melanoleuca ENSAMEG00000002048 N
ENSAMEG00000014764 Ailuropoda melanoleuca ENSAMEG00000014764 N
ENSAMEG00000015014 Ailuropoda melanoleuca ENSAMEG00000015014 I
ENSAMXG00000001873 Astyanax mexicanus ENSAMXG00000001873 N
ENSAMXG00000002473 Astyanax mexicanus ENSAMXG00000002473 N
ENSAMXG00000013383 Astyanax mexicanus ENSAMXG00000013383 N
ENSAPLG00000003822 Anas platyrhynchos ENSAPLG00000003822 N
ENSAPLG00000007386 Anas platyrhynchos ENSAPLG00000007386 N
ENSAPLG00000016052 Anas platyrhynchos ENSAPLG00000016052 N
ST18 Bos taurus ENSBTAG00000005560 N
MYT1 Bos taurus ENSBTAG00000006352 N
ENSBTAP00000038860-D1 Bos grunniens ENSBTAP00000038860-D1 N
MYT1L Canis familiaris ENSCAFG00000003240 N
ST18 Canis familiaris ENSCAFG00000006762 N
MYT1 Canis familiaris ENSCAFG00000013222 N
ST18 Choloepus hoffmanni ENSCHOG00000010565 N
MYT1L Callithrix jacchus ENSCJAG00000007286 N
ST18 Callithrix jacchus ENSCJAG00000014630 N
ST18 Cavia porcellus ENSCPOG00000005486 N
MYT1 Cavia porcellus ENSCPOG00000006790 N
ENSCSAG00000014731 Chlorocebus sabaeus ENSCSAG00000014731 N
ENSCSAG00000016796 Chlorocebus sabaeus ENSCSAG00000016796 N
myt1la Danio rerio ENSDARG00000008209 N
myt1a Danio rerio ENSDARG00000074030 N
myt1b Danio rerio ENSDARG00000102879 N
ST18 Dasypus novemcinctus ENSDNOG00000009682 N
MYT1 Dasypus novemcinctus ENSDNOG00000032037 N
St18 Dipodomys ordii ENSDORG00000002635 N
Myt1 Dipodomys ordii ENSDORG00000006425 N
ST18 Equus caballus ENSECAG00000011546 N
MYT1 Equus caballus ENSECAG00000013810 N
MYT1L Equus caballus ENSECAG00000014657 N
MYT1L Erinaceus europaeus ENSEEUG00000013615 N
ENSFALG00000010174 Ficedula albicollis ENSFALG00000010174 N
ENSFALG00000010354 Ficedula albicollis ENSFALG00000010354 N
MYT1 Felis catus ENSFCAG00000001189 N
ST18 Felis catus ENSFCAG00000008556 N
MYT1L Felis catus ENSFCAG00000013984 N
ST18 Homo sapiens ENSG00000147488 I
MYT1L Homo sapiens ENSG00000186487 I
MYT1 Homo sapiens ENSG00000196132 N
myt1b Gasterosteus aculeatus ENSGACG00000013224 N
ENSGACG00000013255 Gasterosteus aculeatus ENSGACG00000013255 N
ST18 Gasterosteus aculeatus ENSGACG00000017947 N
MYT1 Gallus gallus ENSGALG00000005932 N
ST18 Gallus gallus ENSGALG00000015254 N
MYT1L Gallus gallus ENSGALG00000016384 N
ST18 Gorilla gorilla ENSGGOG00000001223 N
MYT1 Gorilla gorilla ENSGGOG00000006335 N
MYT1L Gorilla gorilla ENSGGOG00000026335 N
ENSLACG00000008399 Latimeria chalumnae ENSLACG00000008399 I
MYT1L Loxodonta africana ENSLAFG00000002751 N
MYT1 Loxodonta africana ENSLAFG00000022251 N
ENSLOCG00000005236 Lepisosteus oculatus ENSLOCG00000005236 N
ENSLOCG00000005847 Lepisosteus oculatus ENSLOCG00000005847 N
ENSLOCG00000017216 Lepisosteus oculatus ENSLOCG00000017216 N
MYT1L Meleagris gallopavo ENSMGAG00000013972 N
MYT1 Microcebus murinus ENSMICG00000003327 N
MYT1 Myotis lucifugus ENSMLUG00000007626 N
ST18 Myotis lucifugus ENSMLUG00000013211 N
MYT1 Macaca mulatta ENSMMUG00000002315 N
ST18 Macaca mulatta ENSMMUG00000008439 N
MYT1L Macaca mulatta ENSMMUG00000009310 I
ENSMMUP00000012198 Macaca fascicularis ENSMMUP00000012198 N
ST18 Monodelphis domestica ENSMODG00000009635 N
MYT1L Monodelphis domestica ENSMODG00000014378 N
MYT1 Monodelphis domestica ENSMODG00000017076 N
ENSMPUG00000006922 Mustela putorius furo ENSMPUG00000006922 N
ENSMPUG00000008741 Mustela putorius furo ENSMPUG00000008741 N
ENSMPUG00000012946 Mustela putorius furo ENSMPUG00000012946 N
Myt1 Mus musculus ENSMUSG00000010505 N
St18 Mus musculus ENSMUSG00000033740 N
Myt1l Mus musculus ENSMUSG00000061911 N
ENSNLEG00000000678 Nomascus leucogenys ENSNLEG00000000678 N
ENSNLEG00000008466 Nomascus leucogenys ENSNLEG00000008466 N
ENSNLEG00000010244 Nomascus leucogenys ENSNLEG00000010244 N
MYT1 Ornithorhynchus anatinus ENSOANG00000004914 N
ST18 Ornithorhynchus anatinus ENSOANG00000007275 N
ENSOANG00000009861 Ornithorhynchus anatinus ENSOANG00000009861 N
ENSOARG00000007966 Ovis aries ENSOARG00000007966 N
ENSOARG00000013407 Ovis aries ENSOARG00000013407 N
ST18 Oryctolagus cuniculus ENSOCUG00000013284 N
MYT1L Oryctolagus cuniculus ENSOCUG00000016764 N
MYT1 Oryctolagus cuniculus ENSOCUG00000024866 N
MYT1 Otolemur garnettii ENSOGAG00000011473 N
ST18 Otolemur garnettii ENSOGAG00000012050 N
ENSONIG00000000499 Oreochromis niloticus ENSONIG00000000499 N
ENSONIG00000009529 Oreochromis niloticus ENSONIG00000009529 N
ENSONIG00000018694 Oreochromis niloticus ENSONIG00000018694 N
ST18 Ochotona princeps ENSOPRG00000001335 N
MYT1 Ochotona princeps ENSOPRG00000015226 N
myt1b Oryzias latipes ENSORLG00000002252 N
myt1la Oryzias latipes ENSORLG00000018130 N
myt1a Oryzias latipes ENSORLG00000020139 N
ENSP00000276480 Macaca fascicularis ENSP00000276480 N
ENSP00000276480-D1 Bos grunniens ENSP00000276480-D1 N
ENSP00000327465 Macaca fascicularis ENSP00000327465 N
ENSPANG00000005639 Papio anubis ENSPANG00000005639 N
ENSPANG00000005908 Papio anubis ENSPANG00000005908 N
ENSPANG00000009233 Papio anubis ENSPANG00000009233 N
MYT1L Procavia capensis ENSPCAG00000015124 N
ENSPFOG00000002613 Poecilia formosa ENSPFOG00000002613 N
ENSPFOG00000014046 Poecilia formosa ENSPFOG00000014046 N
ENSPFOG00000016047 Poecilia formosa ENSPFOG00000016047 N
ENSPPYG00000011263 Pongo abelii ENSPPYG00000011263 N
ENSPPYG00000012686 Pongo abelii ENSPPYG00000012686 N
ENSPSIG00000005126 Pelodiscus sinensis ENSPSIG00000005126 N
ENSPSIG00000010265 Pelodiscus sinensis ENSPSIG00000010265 N
ENSPSIG00000011125 Pelodiscus sinensis ENSPSIG00000011125 N
MYT1L Pan troglodytes ENSPTRG00000011611 N
ST18 Pan troglodytes ENSPTRG00000020245 N
MYT1 Pan troglodytes ENSPTRG00000032477 N
ST18 Pteropus vampyrus ENSPVAG00000013501 N
MYT1 Pteropus vampyrus ENSPVAG00000017398 N
Myt1l Rattus norvegicus ENSRNOG00000004269 N
St18 Rattus norvegicus ENSRNOG00000006200 N
Myt1 Rattus norvegicus ENSRNOG00000017346 N
MYT1L Sorex araneus ENSSARG00000012319 N
ENSSHAG00000012193 Sarcophilus harrisii ENSSHAG00000012193 N
ENSSHAG00000015142 Sarcophilus harrisii ENSSHAG00000015142 N
ST18 Sus scrofa ENSSSCG00000006266 N
MYT1L Sus scrofa ENSSSCG00000029334 N
ENSSTOG00000001345 Ictidomys tridecemlineatus ENSSTOG00000001345 N
ENSSTOG00000008133 Ictidomys tridecemlineatus ENSSTOG00000008133 N
ENSTGUG00000007315 Taeniopygia guttata ENSTGUG00000007315 N
ST18 Taeniopygia guttata ENSTGUG00000010944 N
ENSTGUG00000012971 Taeniopygia guttata ENSTGUG00000012971 N
myt1b Tetraodon nigroviridis ENSTNIG00000003105 N
ENSTNIG00000004354 Tetraodon nigroviridis ENSTNIG00000004354 N
ST18 Tetraodon nigroviridis ENSTNIG00000008501 N
myt1la Tetraodon nigroviridis ENSTNIG00000010716 N
MYT1 Takifugu rubripes ENSTRUG00000002124 N
MYT1L Takifugu rubripes ENSTRUG00000003414 N
ST18 Takifugu rubripes ENSTRUG00000006078 N
myt1a Takifugu rubripes ENSTRUG00000007068 N
myt1la Takifugu rubripes ENSTRUG00000015790 N
ENSTSYG00000006016 Tarsius syrichta ENSTSYG00000006016 N
ENSTSYG00000010425 Tarsius syrichta ENSTSYG00000010425 N
MYT1L Tursiops truncatus ENSTTRG00000008589 N
MYT1 Tursiops truncatus ENSTTRG00000013408 N
ST18 Tursiops truncatus ENSTTRG00000015387 N
ENSXMAG00000002367 Xiphophorus maculatus ENSXMAG00000002367 N
ENSXMAG00000012857 Xiphophorus maculatus ENSXMAG00000012857 N
ENSXMAG00000018975 Xiphophorus maculatus ENSXMAG00000018975 N
Gfo_R005271 Geospiza fortis Gfo_R005271 N
Gfo_R012653 Geospiza fortis Gfo_R012653 N
LotgiG162409 Lottia gigantea LotgiG162409 N
Myotis_brandtii_ST18_10012485 Myotis brandtii Myotis_brandtii_ST18_10012485 N
Ogr14932 Ophisaurus gracilis Ogr14932 N
Pvit_15314 Pogona vitticeps Pvit_15314 N
Pvit_18506 Pogona vitticeps Pvit_18506 N
Sakowv30043989m.g Saccoglossus kowalevskii Sakowv30043989m.g N
SPU_023941 Strongylocentrotus purpuratus SPU_023941 N
myt1.S Xenopus laevis XB-GENE-1009978 N
XP_002934158 Xenopus tropicalis XP_002934158 N
XP_002936343 Xenopus tropicalis XP_002936343 N
XP_002942428 Xenopus tropicalis XP_002942428 N